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Volumn 26, Issue 7, 2009, Pages 675-690

Omacor® (prescription omega-3-acid ethyl esters 90): From severe rhythm disorders to hypertriglyceridemia

Author keywords

Heart failure; Hypertriglyceridemia; Implantable cardioverter defibrillator; Myocardial infarction; Omacor ; Omega 3 fatty acids; Sudden death

Indexed keywords

ANGIOTENSIN RECEPTOR ANTAGONIST; ANTITHROMBOCYTIC AGENT; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; DIURETIC AGENT; DOCOSAHEXAENOIC ACID; HYPOCHOLESTEROLEMIC AGENT; ICOSAPENTAENOIC ACID; NON PRESCRIPTION DRUG; OLIVE OIL; OMEGA 3 FATTY ACID; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; SIMVASTATIN; SPIRONOLACTONE; STEROL REGULATORY ELEMENT BINDING PROTEIN 1C; VERY LOW DENSITY LIPOPROTEIN CHOLESTEROL; ANTIARRHYTHMIC AGENT; ANTIDIABETIC AGENT;

EID: 73349122930     PISSN: 0741238X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12325-009-0045-2     Document Type: Review
Times cited : (34)

References (67)
  • 2
    • 11244328984 scopus 로고    scopus 로고
    • Risk stratification by the "EPA+DHA level" and the "EPA/AA ratio": Focus on anti-inflammatory and antiarrhythmogenic effects of long-chain omega-3 fatty acids
    • DOI 10.1007/s00059-004-2602-4
    • H. Rupp D. Wagner T. Rupp L.M. Schulte B. Maisch 2004 Risk stratification by the "EPA+DHA level" and the "EPA/AA ratio" focus on anti-inflammatory and antiarrhythmogenic effects of long-chain omega-3 fatty acids Herz 29 673 685 15580322 10.1007/s00059-004-2602-4 (Pubitemid 40064639)
    • (2004) Herz , vol.29 , Issue.7 , pp. 673-685
    • Rupp, H.1    Wagner, D.2    Rupp, T.3    Schulte, L.-M.4    Maisch, B.5
  • 3
    • 0023947256 scopus 로고
    • Human absorption of fish oil fatty acids as triacylglycerols, free acids, or ethyl esters
    • 3358766 10.1016/S0006-291X(88)80718-6 1:CAS:528:DyaL1cXkt1aju7s%3D
    • L.D. Lawson B.G. Hughes 1988 Human absorption of fish oil fatty acids as triacylglycerols, free acids, or ethyl esters Biochem Biophys Res Commun 152 328 335 3358766 10.1016/S0006-291X(88)80718-6 1:CAS:528:DyaL1cXkt1aju7s%3D
    • (1988) Biochem Biophys Res Commun , vol.152 , pp. 328-335
    • Lawson, L.D.1    Hughes, B.G.2
  • 4
    • 0023576197 scopus 로고
    • Enteral absorption in man of eicosapentaenoic acid in different chemical forms
    • 2828810 10.1007/BF02533970 1:CAS:528:DyaL1cXjs1KgsA%3D%3D
    • S. el Boustani C. Colette L. Monnier B. Descomps A. Crastes de Paulet F. Mendy 1987 Enteral absorption in man of eicosapentaenoic acid in different chemical forms Lipids 22 711 714 2828810 10.1007/BF02533970 1:CAS:528: DyaL1cXjs1KgsA%3D%3D
    • (1987) Lipids , vol.22 , pp. 711-714
    • El Boustani, S.1    Colette, C.2    Monnier, L.3    Descomps, B.4    Crastes De Paulet, A.5    Mendy, F.6
  • 5
    • 0343642322 scopus 로고
    • Bioavailability of omega-3 fatty acids: Ethylester preparations are as suitable as triglyceride preparations
    • C. Luley H. Wieland J. Grünwald 1990 Bioavailability of omega-3 fatty acids: ethylester preparations are as suitable as triglyceride preparations Akt Ernähr Med 15 123 125
    • (1990) Akt Ernähr Med , vol.15 , pp. 123-125
    • Luley, C.1    Wieland, H.2    Grünwald, J.3
  • 6
    • 0027411287 scopus 로고
    • Lymphatic transport of eicosapentaenoic and docosahexaenoic acids as triglyceride, ethyl ester and free acid, and their effect on cholesterol transport in rats
    • DOI 10.1016/0024-3205(93)90172-Y
    • I. Ikeda Y. Imasato H. Nagao 1993 Lymphatic transport of eicosapentaenoic and docosahexaenoic acids as triglyceride, ethyl ester and free acid, and their effect on cholesterol transport in rats Life Sci 52 1371 1379 8464336 10.1016/0024-3205(93)90172-Y 1:CAS:528:DyaK3sXitV2qs7Y%3D (Pubitemid 223040463)
    • (1993) Life Sciences , vol.52 , Issue.16 , pp. 1371-1379
    • Ikeda, I.1    Imasato, Y.2    Nagao, H.3    Sasaki, E.4    Sugano, M.5    Imaizumi, K.6    Yazawa, K.7
  • 7
    • 0037137299 scopus 로고    scopus 로고
    • Fish consumption, fish oil, omega-3 fatty acids, and cardiovascular disease
    • DOI 10.1161/01.CIR.0000038493.65177.94
    • P.M. Kris-Etherton W.S. Harris L.J. Appel 2002 Fish consumption, fish oil, omega-3 fatty acids, and cardiovascular disease Circulation 106 2747 2757 12438303 10.1161/01.CIR.0000038493.65177.94 (Pubitemid 35364932)
    • (2002) Circulation , vol.106 , Issue.21 , pp. 2747-2757
    • Kris-Etherton, P.M.1    Harris, W.S.2    Appel, L.J.3
  • 8
    • 34447280131 scopus 로고    scopus 로고
    • Microdetermination of fatty acids by gas chromatography and cardiovascular risk stratification by the "ePA+DHA level"
    • 17575804
    • H. Rupp T.P. Rupp D. Wagner P. Alter B. Maisch 2006 Microdetermination of fatty acids by gas chromatography and cardiovascular risk stratification by the "EPA+DHA level" Herz 31 suppl.3 30 49 17575804
    • (2006) Herz , vol.31 , Issue.SUPPL.3 , pp. 30-49
    • Rupp, H.1    Rupp, T.P.2    Wagner, D.3    Alter, P.4    Maisch, B.5
  • 9
    • 73449089123 scopus 로고
    • Die Nationale Verzehrsstudie: Materialien zur Gesundheitsforschung. Wirtschaftsverlag NW Bremerhaven
    • Die Nationale Verzehrsstudie: Materialien zur Gesundheitsforschung (Band 18) [The National Consumption Study: Materials for Health Research]. Bremerhaven: Wirtschaftsverlag NW; 1991.
    • (1991) [The National Consumption Study: Materials for Health Research]
  • 10
    • 0345109256 scopus 로고    scopus 로고
    • Dietary supplementation with N-3 polyunsaturated fatty acids and vitamin E after myocardial infarction: Results of the GISSI-Prevenzione trial
    • DOI 10.1016/S0140-6736(99)07072-5
    • GISSI-Prevenzione Investigators. 1999 Dietary supplementation with n-3 polyunsaturated fatty acids and vitamin E after myocardial infarction: results of the GISSI-Prevenzione trial. Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto miocardico Lancet 354 447 455 10.1016/S0140-6736(99) 07072-5 (Pubitemid 29368922)
    • (1999) Lancet , vol.354 , Issue.9177 , pp. 447-455
    • Marchioli, R.1
  • 14
    • 55349135709 scopus 로고    scopus 로고
    • Differences between dietary supplement and prescription drug omega-3 fatty acid formulations: A legislative and regulatory perspective
    • 19155425 1:CAS:528:DC%2BD1MXislOis7s%3D
    • N. Collins A.P. Tighe S.A. Brunton P.M. Kris-Etherton 2008 Differences between dietary supplement and prescription drug omega-3 fatty acid formulations: a legislative and regulatory perspective J Am Coll Nutr 27 659 666 19155425 1:CAS:528:DC%2BD1MXislOis7s%3D
    • (2008) J Am Coll Nutr , vol.27 , pp. 659-666
    • Collins, N.1    Tighe, A.P.2    Brunton, S.A.3    Kris-Etherton, P.M.4
  • 15
    • 33746796799 scopus 로고    scopus 로고
    • Are the health benefits of fish oils limited by products of oxidation?
    • DOI 10.1079/NRR2006117
    • R. Turner C.H. McLean K.M. Silvers 2006 Are the health benefits of fish oils limited by products of oxidation? Nutr Res Rev 19 53 62 19079875 10.1079/NRR2006117 1:CAS:528:DC%2BD28XoslWls7g%3D (Pubitemid 44174293)
    • (2006) Nutrition Research Reviews , vol.19 , Issue.1 , pp. 53-62
    • Turner, R.1    McLean, C.H.2    Silvers, K.M.3
  • 16
    • 53049110571 scopus 로고    scopus 로고
    • Effect of n-3 polyunsaturated fatty acids in patients with chronic heart failure (the GISSI-HF trial): A randomised, double-blind, placebo-controlled trial
    • GISSI-HF Investigators. 10.1016/S0140-6736(08)61239-8 1:CAS:528:DC%2BD1cXhtF2ku7jF
    • GISSI-HF Investigators. 2008 Effect of n-3 polyunsaturated fatty acids in patients with chronic heart failure (the GISSI-HF trial): a randomised, double-blind, placebo-controlled trial Lancet 372 1223 1230 10.1016/S0140- 6736(08)61239-8 1:CAS:528:DC%2BD1cXhtF2ku7jF
    • (2008) Lancet , vol.372 , pp. 1223-1230
  • 17
    • 57349189353 scopus 로고    scopus 로고
    • Management of acute myocardial infarction in patients presenting with persistent ST-segment elevation: The Task Force on the Management of ST-Segment Elevation Acute Myocardial Infarction of the European Society of Cardiology
    • 19004841 10.1093/eurheartj/ehn416 1:CAS:528:DC%2BD1MXmtl2hsw%3D%3D
    • F. Van de Werf J. Bax A. Betriu 2008 Management of acute myocardial infarction in patients presenting with persistent ST-segment elevation: the Task Force on the Management of ST-Segment Elevation Acute Myocardial Infarction of the European Society of Cardiology Eur Heart J 29 2909 2945 19004841 10.1093/eurheartj/ehn416 1:CAS:528:DC%2BD1MXmtl2hsw%3D%3D
    • (2008) Eur Heart J , vol.29 , pp. 2909-2945
    • Van De Werf, F.1    Bax, J.2    Betriu, A.3
  • 19
    • 0028344229 scopus 로고
    • Prevention of ischemia-induced ventricular fibrillation by omega 3 fatty acids
    • 8183925 10.1073/pnas.91.10.4427 1:CAS:528:DyaK2cXktVOqu74%3D
    • G.E. Billman H. Hallaq A. Leaf 1994 Prevention of ischemia-induced ventricular fibrillation by omega 3 fatty acids Proc Natl Acad Sci U S A 91 4427 4430 8183925 10.1073/pnas.91.10.4427 1:CAS:528:DyaK2cXktVOqu74%3D
    • (1994) Proc Natl Acad Sci U S A , vol.91 , pp. 4427-4430
    • Billman, G.E.1    Hallaq, H.2    Leaf, A.3
  • 20
    • 9844268409 scopus 로고
    • No obvious influence of dietary fatty acid intake on cardiac sodium current of the rat
    • R. Eickhorn H. Isensee R. Jacob H. Antoni 1992 No obvious influence of dietary fatty acid intake on cardiac sodium current of the rat Pflugers Arch 420 suppl.1 334
    • (1992) Pflugers Arch , vol.420 , Issue.SUPPL.1 , pp. 334
    • Eickhorn, R.1    Isensee, H.2    Jacob, R.3    Antoni, H.4
  • 21
    • 27844607043 scopus 로고    scopus 로고
    • Prevention of fatal arrhythmias in high-risk subjects by fish oil n-3 fatty acid intake
    • DOI 10.1161/CIRCULATIONAHA.105.549527
    • A. Leaf C.M. Albert M. Josephson 2005 Prevention of fatal arrhythmias in high-risk subjects by fish oil n-3 fatty acid intake Circulation 112 2762 2768 16267249 10.1161/CIRCULATIONAHA.105.549527 1:CAS:528:DC%2BD2MXhtFCru7bK (Pubitemid 41641669)
    • (2005) Circulation , vol.112 , Issue.18 , pp. 2762-2768
    • Leaf, A.1    Albert, C.M.2    Josephson, M.3    Steinhaus, D.4    Kluger, J.5    Kang, J.X.6    Cox, B.7    Zhang, H.8    Schoenfeld, D.9
  • 22
    • 33746263858 scopus 로고    scopus 로고
    • The bioavailability and pharmacodynamics of different concentrations of omega-3 acid ethyl esters
    • DOI 10.1016/j.plefa.2006.04.003, PII S0952327806000536
    • M. Bryhn H. Hansteen T. Schanche S.E. Aakre 2006 The bioavailability and pharmacodynamics of different concentrations of omega-3 acid ethyl esters Prostaglandins Leukot Essent Fatty Acids 75 19 24 16806871 10.1016/j.plefa.2006. 04.003 1:CAS:528:DC%2BD28XntlCrurw%3D (Pubitemid 44096989)
    • (2006) Prostaglandins Leukotrienes and Essential Fatty Acids , vol.75 , Issue.1 , pp. 19-24
    • Bryhn, M.1    Hansteen, H.2    Schanche, T.3    Aakre, S.E.4
  • 23
    • 32044449624 scopus 로고    scopus 로고
    • Membrane effects of the n-3 fish oil fatty acids, which prevent fatal ventricular arrhythmias
    • DOI 10.1007/s00232-005-0789-9
    • A. Leaf Y.F. Xiao J.X. Kang G.E. Billman 2005 Membrane effects of the n-3 fish oil fatty acids, which prevent fatal ventricular arrhythmias J Membr Biol 206 129 139 16456723 10.1007/s00232-005-0789-9 1:CAS:528:DC%2BD28XhtFWmt7k%3D (Pubitemid 43199146)
    • (2005) Journal of Membrane Biology , vol.206 , Issue.2 , pp. 129-139
    • Leaf, A.1    Xiao, Y.-F.2    Kang, J.X.3    Billman, G.E.4
  • 24
    • 0035702594 scopus 로고    scopus 로고
    • Myocardial membrane fatty acids and the antiarrhythmic actions of dietary fish oil in animal models
    • 11837983 10.1007/s11745-001-0692-x 1:CAS:528:DC%2BD38XovVSmtg%3D%3D
    • P.L. McLennan 2001 Myocardial membrane fatty acids and the antiarrhythmic actions of dietary fish oil in animal models Lipids 36 suppl.1 S111 S114 11837983 10.1007/s11745-001-0692-x 1:CAS:528:DC%2BD38XovVSmtg%3D%3D
    • (2001) Lipids , vol.36 , Issue.SUPPL.1
    • McLennan, P.L.1
  • 25
    • 11844304908 scopus 로고    scopus 로고
    • Measurement of organochlorines in commercial over-the-counter fish oil preparations: Implications for dietary and therapeutic recommendations for omega-3 fatty acids and a review of the literature
    • 15628911 1:CAS:528:DC%2BD2MXhtVSksbk%3D
    • S.F. Melanson E.L. Lewandrowski J.G. Flood K.B. Lewandrowski 2005 Measurement of organochlorines in commercial over-the-counter fish oil preparations: implications for dietary and therapeutic recommendations for omega-3 fatty acids and a review of the literature Arch Pathol Lab Med 129 74 77 15628911 1:CAS:528:DC%2BD2MXhtVSksbk%3D
    • (2005) Arch Pathol Lab Med , vol.129 , pp. 74-77
    • Melanson, S.F.1    Lewandrowski, E.L.2    Flood, J.G.3    Lewandrowski, K.B.4
  • 26
    • 73449119986 scopus 로고    scopus 로고
    • Food Standards Agency web site. June 2002. Available at
    • Dioxins and dioxin-like PCBs in fish oil supplements. Food Standards Agency web site. June 2002. Available at: http://www.food.gov.uk/multimedia/ pdfs/26diox.pdf. Last accessed June 2009.
    • Dioxins and Dioxin-like PCBs in Fish Oil Supplements
  • 28
    • 34548319692 scopus 로고    scopus 로고
    • Efficacy and tolerability of adding prescription Omega-3 fatty acids 4 g/d to Simvastatin 40 mg/d in hypertriglyceridemic patients: An 8-week, randomized, double-blind, placebo-controlled study
    • DOI 10.1016/j.clinthera.2007.07.018, PII S014929180700210X
    • M.H. Davidson E.A. Stein H.E. Bays 2007 Efficacy and tolerability of adding prescription omega-3 fatty acids 4 g/d to simvastatin 40 mg/d in hypertriglyceridemic patients: an 8-week, randomized, double-blind, placebo-controlled study Clin Ther 29 1354 1367 17825687 10.1016/j.clinthera. 2007.07.018 1:CAS:528:DC%2BD2sXhtVemurjN (Pubitemid 47348116)
    • (2007) Clinical Therapeutics , vol.29 , Issue.7 , pp. 1354-1367
    • Davidson, M.H.1    Stein, E.A.2    Bays, H.E.3    Maki, K.C.4    Doyle, R.T.5    Shalwitz, R.A.6    Ballantyne, C.M.7    Ginsberg, H.N.8
  • 29
    • 33747203207 scopus 로고    scopus 로고
    • A multi-country health economic evaluation of highly concentrated N-3 polyunsaturated fatty acids in secondary prevention after myocardial infarction
    • DOI 10.2165/00019053-200624080-00005
    • M. Lamotte L. Annemans P. Kawalec Y. Zoellner 2006 A multi-country health-economic evaluation of highly concentrated n-3 polyunsaturated fatty acids in the secondary prevention after myocardial infarction Pharmacoeconomics 24 783 795 16898848 10.2165/00019053-200624080-00005 (Pubitemid 44232106)
    • (2006) PharmacoEconomics , vol.24 , Issue.8 , pp. 783-795
    • Lamotte, M.1    Annemans, L.2    Kawalec, P.3    Zoellner, Y.4
  • 30
    • 33746137198 scopus 로고    scopus 로고
    • A cost-effectiveness analysis of n-3 PUFA (Omacor®) treatment in post-MI patients
    • DOI 10.1111/j.1742-1241.2006.01009.x
    • S. Quilici M. Martin A. McGuire Y. Zoellner 2006 A cost-effectiveness analysis of n-3 PUFA (Omacor) treatment in post-MI patients Int J Clin Pract 60 922 932 16893435 10.1111/j.1742-1241.2006.01009.x 1:CAS:528:DC%2BD28XpvVemsb4%3D (Pubitemid 44082283)
    • (2006) International Journal of Clinical Practice , vol.60 , Issue.8 , pp. 922-932
    • Quilici, S.1    Martin, M.2    McGuire, A.3    Zoellner, Y.4
  • 32
    • 0028855987 scopus 로고
    • Dietary intake and cell membrane levels of long-chain n-3 polyunsaturated fatty acids and the risk of primary cardiac arrest
    • 7563561 10.1001/jama.274.17.1363 1:CAS:528:DyaK2MXpsl2ksL0%3D
    • D.S. Siscovick T.E. Raghunathan I. King 1995 Dietary intake and cell membrane levels of long-chain n-3 polyunsaturated fatty acids and the risk of primary cardiac arrest JAMA 274 1363 1367 7563561 10.1001/jama.274.17.1363 1:CAS:528:DyaK2MXpsl2ksL0%3D
    • (1995) JAMA , vol.274 , pp. 1363-1367
    • Siscovick, D.S.1    Raghunathan, T.E.2    King, I.3
  • 33
    • 2942724415 scopus 로고    scopus 로고
    • The Omega-3 Index: A new risk factor for death from coronary heart disease?
    • DOI 10.1016/j.ypmed.2004.02.030, PII S0091743504000878
    • W.S. Harris C. von Schacky 2004 The Omega-3 Index: a new risk factor for death from coronary heart disease? Prev Med 39 212 220 15208005 10.1016/j.ypmed.2004.02.030 1:CAS:528:DC%2BD2cXltVCisL4%3D (Pubitemid 38797975)
    • (2004) Preventive Medicine , vol.39 , Issue.1 , pp. 212-220
    • Harris, W.S.1    Von Schacky, C.2
  • 34
    • 33747105864 scopus 로고    scopus 로고
    • Tissue omega-6/omega-3 fatty acid ratio and risk for coronary artery disease
    • DOI 10.1016/j.amjcard.2005.12.023, PII S0002914905021867
    • W.S. Harris B. Assaad W.C. Poston 2006 Tissue omega-6/omega-3 fatty acid ratio and risk for coronary artery disease Am J Cardiol 98 19i 26i 16919513 10.1016/j.amjcard.2005.12.023 1:CAS:528:DC%2BD28XpslWitbg%3D (Pubitemid 44223361)
    • (2006) American Journal of Cardiology , vol.98 , Issue.4 SUPPL. 1 , pp. 19-26
    • Harris, W.S.1    Assaad, B.2    Poston, W.C.3
  • 35
    • 2942532780 scopus 로고    scopus 로고
    • Early modifications of fatty acid composition in plasma phospholipids, platelets and mononucleates of healthy volunteers after low doses of n-3 polyunsaturated fatty acids
    • DOI 10.1007/s00228-004-0758-8
    • D. Di Stasi R. Bernasconi R. Marchioli 2004 Early modifications of fatty acid composition in plasma phospholipids, platelets and mononucleates of healthy volunteers after low doses of n-3 polyunsaturated fatty acids Eur J Clin Pharmacol 60 183 190 15069592 10.1007/s00228-004-0758-8 1:CAS:528: DC%2BD2cXjvFKnt7c%3D (Pubitemid 38757129)
    • (2004) European Journal of Clinical Pharmacology , vol.60 , Issue.3 , pp. 183-190
    • Di Stasi, D.1    Bernasconi, R.2    Marchioli, R.3    Marfisi, R.M.4    Rossi, G.5    Tognoni, G.6    Tacconi, M.T.7
  • 36
    • 58749095701 scopus 로고    scopus 로고
    • N-3 polyunsaturated fatty acids and statins in heart failure
    • 19186263 10.1016/S0140-6736(09)60127-6
    • H. Rupp T.P. Rupp P. Alter B. Maisch 2009 N-3 polyunsaturated fatty acids and statins in heart failure Lancet 373 378 379 19186263 10.1016/S0140-6736(09) 60127-6
    • (2009) Lancet , vol.373 , pp. 378-379
    • Rupp, H.1    Rupp, T.P.2    Alter, P.3    Maisch, B.4
  • 38
    • 53049102746 scopus 로고    scopus 로고
    • Statins and n-3 fatty acid supplementation in heart failure
    • 18757087 10.1016/S0140-6736(08)61241-6
    • G.C. Fonarow 2008 Statins and n-3 fatty acid supplementation in heart failure Lancet 372 1195 1196 18757087 10.1016/S0140-6736(08)61241-6
    • (2008) Lancet , vol.372 , pp. 1195-1196
    • Fonarow, G.C.1
  • 41
    • 73449140163 scopus 로고    scopus 로고
    • Randomized trial of omega-3 fatty acids on top of modern therapy after acute myocardial infarction: The OMEGA-trial
    • March 30 Orlando, FL, USA
    • Senges J. Randomized trial of omega-3 fatty acids on top of modern therapy after acute myocardial infarction: the OMEGA-trial. Presented at American College of Cardiology annual meeting; March 30, 2009; Orlando, FL, USA. Available at: http://www.cardiosource.com/rapidnewssummaries/acc09.asp. Last accessed June 2009.
    • (2009) Presented at American College of Cardiology Annual Meeting
    • Senges, J.1
  • 43
    • 73449089122 scopus 로고    scopus 로고
    • Heart Rhythm Society [press release]. Boston, MA; May 14 Available at
    • Heart Rhythm Society. Late-breaking clinical trial results announced at Heart Rhythm 2009: MADITII trial [press release]. Boston, MA; May 14, 2009. Available at: http://www.hrsonline.org/News/Media/press-releases/MADIT-II- trial09.cfm. Last accessed June 2009.
    • (2009) Late-breaking Clinical Trial Results Announced at Heart Rhythm 2009: MADITII Trial
  • 45
    • 10044271050 scopus 로고    scopus 로고
    • Prophylactic implantable cardioverter-defibrillators after myocardial infarction - Not for everyone
    • DOI 10.1056/NEJMe048230
    • A.M. Gillis 2004 Prophylactic implantable cardioverter-defibrillators after myocardial infarction-not for everyone N Engl J Med 351 2540 2542 15590957 10.1056/NEJMe048230 1:CAS:528:DC%2BD2cXhtVGksbbJ (Pubitemid 39603159)
    • (2004) New England Journal of Medicine , vol.351 , Issue.24 , pp. 2540-2542
    • Gillis, A.M.1
  • 46
    • 73449111997 scopus 로고    scopus 로고
    • American College of Cardiology web site. Available at
    • ACC.09/i2 Summit clinical trial summary slides. American College of Cardiology web site. Available at: http://www.cardiosource.com/img/ACC09- Compilation.ppt. Last accessed June 2009.
    • ACC.09/i2 Summit Clinical Trial Summary Slides
  • 47
    • 71549155496 scopus 로고    scopus 로고
    • A new method to assess ventricular wall stress in patients with heart failure and its relation to heart rate variability
    • Oct 24 [Epub ahead of print]
    • Alter P, Rupp H, Rominger MB, et al. A new method to assess ventricular wall stress in patients with heart failure and its relation to heart rate variability. Int J Cardiol. 2008; Oct 24 [Epub ahead of print].
    • (2008) Int J Cardiol
    • Alter, P.1    Rupp, H.2    Rominger, M.B.3
  • 48
    • 60849097566 scopus 로고    scopus 로고
    • Depression of heart rate variability in patients with increased ventricular wall stress
    • 19250107 10.1111/j.1540-8159.2008.02223.x
    • P. Alter H. Rupp M.B. Rominger 2009 Depression of heart rate variability in patients with increased ventricular wall stress Pacing Clin Electrophysiol 32 suppl.1 S26 S31 19250107 10.1111/j.1540-8159.2008.02223.x
    • (2009) Pacing Clin Electrophysiol , vol.32 , Issue.SUPPL.1
    • Alter, P.1    Rupp, H.2    Rominger, M.B.3
  • 49
    • 36348950386 scopus 로고    scopus 로고
    • A new methodological approach to assess cardiac work by pressure-volume and stress-length relations in patients with aortic valve stenosis and dilated cardiomyopathy
    • DOI 10.1007/s00424-007-0323-2
    • P. Alter H. Rupp M.B. Rominger K.J. Klose B. Maisch 2008 A new methodological approach to assess cardiac work by pressure-volume and stress-length relations in patients with aortic valve stenosis and dilated cardiomyopathy Pflugers Arch 455 627 636 17721708 10.1007/s00424-007-0323-2 1:CAS:528:DC%2BD2sXhtlCgt7%2FF (Pubitemid 350160477)
    • (2008) Pflugers Archiv European Journal of Physiology , vol.455 , Issue.4 , pp. 627-636
    • Alter, P.1    Rupp, H.2    Rominger, M.B.3    Klose, K.J.4    Maisch, B.5
  • 50
    • 36348932124 scopus 로고    scopus 로고
    • Relation of B-type natriuretic peptide to left ventricular wall stress as assessed by cardiac magnetic resonance imaging in patients with dilated cardiomyopathy
    • DOI 10.1139/Y07-076
    • P. Alter H. Rupp M.B. Rominger 2007 Relation of B-type natriuretic peptide to left ventricular wall stress as assessed by cardiac magnetic resonance imaging in patients with dilated cardiomyopathy Can J Physiol Pharmacol 85 790 799 17901889 10.1139/Y07-076 1:CAS:528:DC%2BD2sXht1ajtbfI (Pubitemid 350144739)
    • (2007) Canadian Journal of Physiology and Pharmacology , vol.85 , Issue.8 , pp. 790-799
    • Alter, P.1    Rupp, H.2    Rominger, M.B.3    Vollrath, A.4    Czerny, F.5    Klose, K.J.6    Maisch, B.7
  • 51
    • 45449096279 scopus 로고    scopus 로고
    • B-type natriuretic peptide and wall stress in dilated human heart
    • 18461428 10.1007/s11010-008-9779-4 1:CAS:528:DC%2BD1cXntFKnu7c%3D
    • P. Alter H. Rupp M.B. Rominger 2008 B-type natriuretic peptide and wall stress in dilated human heart Mol Cell Biochem 314 179 191 18461428 10.1007/s11010-008-9779-4 1:CAS:528:DC%2BD1cXntFKnu7c%3D
    • (2008) Mol Cell Biochem , vol.314 , pp. 179-191
    • Alter, P.1    Rupp, H.2    Rominger, M.B.3
  • 53
    • 42549108293 scopus 로고    scopus 로고
    • Omega-3 fatty acid supplementation reduces one-year risk of atrial fibrillation in patients hospitalized with myocardial infarction
    • 18309477 10.1007/s00228-008-0464-z 1:CAS:528:DC%2BD1cXkvFymurk%3D
    • A. Macchia S. Monte F. Pellegrini 2008 Omega-3 fatty acid supplementation reduces one-year risk of atrial fibrillation in patients hospitalized with myocardial infarction Eur J Clin Pharmacol 64 627 634 18309477 10.1007/s00228-008-0464-z 1:CAS:528:DC%2BD1cXkvFymurk%3D
    • (2008) Eur J Clin Pharmacol , vol.64 , pp. 627-634
    • MacChia, A.1    Monte, S.2    Pellegrini, F.3
  • 54
    • 84950170723 scopus 로고    scopus 로고
    • Dietary fish oil protects against stretch-induced vulnerability to atrial fibrillation in a rabbit model
    • DOI 10.1111/j.1540-8167.2005.50007.x
    • D.M. Ninio K.J. Murphy P.R. Howe D.A. Saint 2005 Dietary fish oil protects against stretch-induced vulnerability to atrial fibrillation in a rabbit model J Cardiovasc Electrophysiol 16 1189 1194 16302902 10.1111/j.1540-8167.2005.50007.x (Pubitemid 43920007)
    • (2005) Journal of Cardiovascular Electrophysiology , vol.16 , Issue.11 , pp. 1189-1194
    • Ninio, D.M.1    Murphy, K.J.2    Howe, P.R.3    Saint, D.A.4
  • 55
    • 58449121898 scopus 로고    scopus 로고
    • Omega-3 polyunsaturated fatty acids inhibit transient outward and ultra-rapid delayed rectifier K+currents and Na+current in human atrial myocytes
    • 19029136 10.1093/cvr/cvn322 1:CAS:528:DC%2BD1MXntVOjtw%3D%3D
    • G.R. Li H.Y. Sun X.H. Zhang 2009 Omega-3 polyunsaturated fatty acids inhibit transient outward and ultra-rapid delayed rectifier K+currents and Na+current in human atrial myocytes Cardiovasc Res 81 286 293 19029136 10.1093/cvr/cvn322 1:CAS:528:DC%2BD1MXntVOjtw%3D%3D
    • (2009) Cardiovasc Res , vol.81 , pp. 286-293
    • Li, G.R.1    Sun, H.Y.2    Zhang, X.H.3
  • 56
    • 43449128895 scopus 로고    scopus 로고
    • Rationale for prescription omega-3-acid ethyl ester therapy for hypertriglyceridemia: A primer for clinicians
    • DOI 10.1358/dot.2008.44.3.1166387
    • H. Bays 2008 Rationale for prescription omega-3-acid ethyl ester therapy for hypertriglyceridemia: a primer for clinicians Drugs Today (Barc) 44 205 246 10.1358/dot.2008.44.3.1166387 1:CAS:528:DC%2BD1cXmtlSntbY%3D (Pubitemid 351669107)
    • (2008) Drugs of Today , vol.44 , Issue.3 , pp. 205-246
    • Bays, H.1
  • 57
    • 0026546031 scopus 로고
    • Influence of diet and carnitine palmitoyltransferase i inhibition on myosin and sarcoplasmic reticulum
    • 1537736 1:CAS:528:DyaK38XitFensbk%3D
    • H. Rupp R. Wahl M. Hansen 1992 Influence of diet and carnitine palmitoyltransferase I inhibition on myosin and sarcoplasmic reticulum J Appl Physiol 72 352 360 1537736 1:CAS:528:DyaK38XitFensbk%3D
    • (1992) J Appl Physiol , vol.72 , pp. 352-360
    • Rupp, H.1    Wahl, R.2    Hansen, M.3
  • 58
    • 33747188960 scopus 로고    scopus 로고
    • Antiatherosclerotic and antithrombotic effects of omega-3 fatty acids
    • 16919516 10.1016/j.amjcard.2005.12.026 1:CAS:528:DC%2BD28XpslWitbc%3D
    • J.G. Robinson N.J. Stone 2006 Antiatherosclerotic and antithrombotic effects of omega-3 fatty acids Am J Cardiol 98 39i 49i 16919516 10.1016/j.amjcard.2005.12.026 1:CAS:528:DC%2BD28XpslWitbc%3D
    • (2006) Am J Cardiol , vol.98
    • Robinson, J.G.1    Stone, N.J.2
  • 59
    • 33747128489 scopus 로고    scopus 로고
    • Mechanisms for the hypotriglyceridemic effect of marine omega-3 fatty acids
    • DOI 10.1016/j.amjcard.2005.12.024, PII S0002914905021879
    • M.H. Davidson 2006 Mechanisms for the hypotriglyceridemic effect of marine omega-3 fatty acids Am J Cardiol 98 27i 33i 16919514 10.1016/j.amjcard. 2005.12.024 1:CAS:528:DC%2BD28XpslWitbk%3D (Pubitemid 44223362)
    • (2006) American Journal of Cardiology , vol.98 , Issue.4 SUPPL. 1 , pp. 27-33
    • Davidson, M.H.1
  • 60
    • 0033214097 scopus 로고    scopus 로고
    • In contrast with docosahexaenoic acid, eicosapentaenoic acid and hypolipidaemic derivatives decrease hepatic synthesis and secretion of triacylglycerol by decreased diacylglycerol acyltransferase activity and stimulation of fatty acid oxidation
    • DOI 10.1042/0264-6021:3430191
    • R.K. Berge L. Madsen H. Vaagenes K.J. Tronstad M. Gottlicher A.C. Rustan 1999 In contrast with docosahexaenoic acid, eicosapentaenoic acid and hypolipidaemic derivatives decrease hepatic synthesis and secretion of triacylglycerol by decreased diacylglycerol acyltransferase activity and stimulation of fatty acid oxidation Biochem J 343 191 197 10493929 10.1042/0264-6021:3430191 1:CAS:528:DyaK1MXmvVyju7k%3D (Pubitemid 29473895)
    • (1999) Biochemical Journal , vol.343 , Issue.1 , pp. 191-197
    • Berge, R.K.1    Madsen, L.2    Vaagenes, H.3    Tronstad, K.J.4    Gottlicher, M.5    Rustan, A.C.6
  • 61
    • 64749095070 scopus 로고    scopus 로고
    • Effects of fenofibrate treatment on cardiovascular disease risk in 9,795 individuals with type 2 diabetes and various components of the metabolic syndrome: The Fenofibrate Intervention and Event Lowering in Diabetes (FIELD) study
    • 18984774 10.2337/dc08-1543 1:CAS:528:DC%2BD1MXjvVyqt7s%3D
    • R. Scott R. O'Brien G. Fulcher 2009 Effects of fenofibrate treatment on cardiovascular disease risk in 9,795 individuals with type 2 diabetes and various components of the metabolic syndrome: the Fenofibrate Intervention and Event Lowering in Diabetes (FIELD) study Diabetes Care 32 493 498 18984774 10.2337/dc08-1543 1:CAS:528:DC%2BD1MXjvVyqt7s%3D
    • (2009) Diabetes Care , vol.32 , pp. 493-498
    • Scott, R.1    O'Brien, R.2    Fulcher, G.3
  • 62
    • 67449108376 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-alpha (PPARalpha): At the crossroads of obesity, diabetes and cardiovascular disease
    • 19386311 10.1016/j.atherosclerosis.2009.03.008 1:CAS:528: DC%2BD1MXnsFags70%3D
    • J.C. Fruchart 2009 Peroxisome proliferator-activated receptor-alpha (PPARalpha): at the crossroads of obesity, diabetes and cardiovascular disease Atherosclerosis 205 1 8 19386311 10.1016/j.atherosclerosis.2009.03.008 1:CAS:528:DC%2BD1MXnsFags70%3D
    • (2009) Atherosclerosis , vol.205 , pp. 1-8
    • Fruchart, J.C.1
  • 63
    • 0035082655 scopus 로고    scopus 로고
    • A randomized trial of high-dose compared with low-dose omega-3 fatty acids in severe IgA nephropathy
    • 11274240 1:CAS:528:DC%2BD3MXjtVWgt78%3D
    • J.V. Donadio Jr. T.S. Larson E.J. Bergstralh J.P. Grande 2001 A randomized trial of high-dose compared with low-dose omega-3 fatty acids in severe IgA nephropathy J Am Soc Nephrol 12 791 799 11274240 1:CAS:528: DC%2BD3MXjtVWgt78%3D
    • (2001) J Am Soc Nephrol , vol.12 , pp. 791-799
    • Donadio, Jr.J.V.1    Larson, T.S.2    Bergstralh, E.J.3    Grande, J.P.4
  • 64
    • 34248196075 scopus 로고    scopus 로고
    • Secondary prevention of CHD in UK men: The diet and reinfarction trial and its sequel
    • DOI 10.1017/S0029665107005241, PII S0029665107005241
    • M.L. Burr 2007 Secondary prevention of CHD in UK men: the Diet and Reinfarction Trial and its sequel Proc Nutr Soc 66 9 15 17343767 10.1017/S0029665107005241 (Pubitemid 46748239)
    • (2007) Proceedings of the Nutrition Society , vol.66 , Issue.1 , pp. 9-15
    • Burr, M.L.1
  • 65
    • 19444364923 scopus 로고    scopus 로고
    • Fatty acid oxidation inhibition with PPARα activation (FOXIB/PPARα) for normalizing gene expression in heart failure?
    • DOI 10.1016/j.cardiores.2005.03.023, PII S0008636305001719
    • H. Rupp T.P. Rupp B. Maisch 2005 Fatty acid oxidation inhibition with PPARalpha activation (FOXIB/PPARalpha) for normalizing gene expression in heart failure? Cardiovasc Res 66 423 426 15914105 10.1016/j.cardiores.2005.03.023 1:CAS:528:DC%2BD2MXks1antbg%3D (Pubitemid 40725753)
    • (2005) Cardiovascular Research , vol.66 , Issue.3 , pp. 423-426
    • Rupp, H.1    Rupp, T.P.2    Maisch, B.3
  • 66
    • 33845575790 scopus 로고    scopus 로고
    • Acute heart failure - Basic pathomechanism and new drug targets
    • DOI 10.1007/s00059-006-2911-x
    • H. Rupp T.P. Rupp P. Alter B. Maisch 2006 Acute heart failure- basic pathomechanism and new drug targets Herz 31 727 735 17149674 10.1007/s00059-006-2911-x (Pubitemid 44934645)
    • (2006) Herz , vol.31 , Issue.8 , pp. 727-735
    • Rupp, H.1    Rupp, T.P.2    Alter, P.3    Maisch, B.4
  • 67
    • 0034687149 scopus 로고    scopus 로고
    • Lisinopril-mediated regression of myocardial fibrosis in patients with hypertensive heart disease
    • 10993857 1:CAS:528:DC%2BD3cXntFKksbY%3D
    • C.G. Brilla R.C. Funck H. Rupp 2000 Lisinopril-mediated regression of myocardial fibrosis in patients with hypertensive heart disease Circulation 102 1388 1393 10993857 1:CAS:528:DC%2BD3cXntFKksbY%3D
    • (2000) Circulation , vol.102 , pp. 1388-1393
    • Brilla, C.G.1    Funck, R.C.2    Rupp, H.3


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