X-ray microcomputed tomography as a tool for the investigation of the biodistribution of magnetic nanoparticles

Nanomedicine

Volumn 4, Issue 8, 2009, Pages 981-990

  Rahn, H ^a   Odenbach, S ^a  

^a DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

Author keywords

Computed tomography; CT; Ferrofluid; Magnetic nanoparticle; Microcomputed tomography; Minimal invasive cancer treatment; X ray; CT

Indexed keywords

MAGNETIC NANOPARTICLE; MITOXANTRONE; NANOPARTICLE;

ALGORITHM; ARTICLE; ATTENUATION; COMPUTER ASSISTED TOMOGRAPHY; DRUG DISTRIBUTION; HYPERTHERMIA; MAGNETIC FIELD; MINIMALLY INVASIVE PROCEDURE; NONHUMAN; PRIORITY JOURNAL; PROCESS DESIGN; RADIATION; SCINTILLATION; SYNCHROTRON; X RAY DIFFRACTION; X RAY TUBE;

EID: 73349118483     PISSN: 17435889     EISSN: None     Source Type: Journal    
DOI: 10.2217/nnm.09.82     Document Type: Article

References (58)

1. Roentgen WC: Eine neue Art von Strahlen, Sitzungsberichte der Physikalisch-Medicinisch Gesellschaft zu Würzburg, 132-141 (1895). ■■ Introduction of x-ray as a new kind of radiation.
2. Radon J: Berichte der Sächsischen Akademie der Wissenschaften. Leipzig, Germany (1917).
3. Kak AC, Slaney M: Principles of Computerized Tomographic Imaging. O'Malley RE Jr (Ed.). IEEE Press, NY, USA, 56-60 (1999).
4. Hounsfield GN: Nobel Award address. Computed medical imaging. Med. Phys. 7(4), 283-290 (1980). ■■ Describes the very basics of computed tomography.
5. Cormack AM: Nobel Award address. Early two-dimensional reconstruction and recent topics stemming from it. Med. Phys. 7(4), 277-282 (1980).
6. Kalender WA: Computed Tomography. Publicis Corporate Publishing, Erlangen, Germany, 37-38 (2006).
7. Stenner P, Kachelries M: Dual energy control (DEEC) for computional tomography: algorithm and simulation study. Med. Phys. 35(11), 5054-5060, (2008)
8. Elliott JC, Dover SD: X-ray microtomography. J. Microscopy 126, 211-213 (1982). ■■ Presentation of first microtomographic images.
9. Feldkamp LA, David L, Kress J: Practical cone beam algorithm. J. Opt. Soc. Am. 1, 612-619 (1984).
10. Als-Nielsen J, McMorrow D: Elements of Modern X-ray Physics. John Wiley & Sons Ltd, NY, USA, 30-40 (2000).
11. Hasse B, Rahn H, Odenbach S, Beckmann F, Reimers W: First results of the DITO-experiment at the HARWI II Beamline at GKSS/DESY. Mater. Sci. Forum 571-572, 201-209 (2008).
12. Johns HE, Cunningham JR: Physics of Radiology. Thomas CC (Ed.). Springfield, IL, USA (1983).
13. Hsieh J: Computed Tomography: Principles, Design, Artifacts, and Recent Advances. SPIE Press, Bellingham, WA, USA (2003).
14. Brooks AR, Di Chiro G: Beam hardening in x-ray reconstructive tomography. Phys. Med. Biol. 21(3), 390-398 (1976).
15. Herman GT: Correction for beam hardening in computed tomography. Phys. Med. Biol. 24(1), 81-106 (1979).
16. So A, Hsieh J, Li JY, Lee TY: Beam hardening correction in CT myocardial perfusion measurement. Phys. Med. Biol. 54, 3031-3050 (2009).
17. Kneller E: Ferromagnetismus. Springer, Berlin, Germany (1962).
18. Odenbach S: Recent progress in magnetic fluid research, J. Phys. Condens. Matter. 16, R1135-R1150, (2004).
19. Gordon RT, Hines JR, Gordon DA: Biophysical approach to cancer treatment via intracellular temperature and biophyisical alterations. Med. Hypotheses 5, 83-102 (1979).
20. Hergt R, Hiergeist R, Zeisberger M et al.: Magnetic properties of bacterial magnetosomes as potential diagnostic and therapeutic tools. J. Magn. Magn. Mater. 293, 80-86 (2005).
21. Hergt R, Andrä W: Magnetic hyperthermia and thermoablation. In: Magnetism in Medicine (2nd Edition). Andrä W, Nowak H (Eds). WILEY-VCH Verlag, Weinheim, Germany, 550-570 (2007).
22. Bruners PH, Braunschweig T, Hodenius M et al.: Thermoablation of malignant kidney tumors using magnetic nanoparticles: an in vivo feasibility study in a rabbit model. Cardiovasc. Intervent. Radiol. (2009) (Epub ahead of print).
23. Hilger I, Andrä W, Bähring R, Daum A, Hergt R, Kaiser WA: Evaluation of temperature increase with different amounts of magnetite in liver tissue samples. Invest. Radiol. 32, 705-712 (1997).
24. Hilger I, Hergt R, Kaiser WA: Effects of magnetic thermoablation in muscle tissue using iron oxide particles: an in vitro study. Invest. Radiol. 35, 170-179 (2000).
25. Hilger I, Andrä W, Hergt R, Hiergeist R, Schubert H, Kaiser WA: Electromagnetic heating of breast tumors in interventional radiology: in vitro and in vivo studies in human cadavers and mice. J. Radiol. 218(2), 570-575 (2001).
26. Hilger I, Dietmar E, Linß W et al.: Developments for the minimally invasive treatment of tumors by targeted magnetic heating. J. Phys. Condens. Matter 18(38), S2951-S2958 (2006).
27. Johannsen M, Jordan A, Scholz R et al.: Evaluation of magnetic fluid hyperthermia in a standard rat model of prostate cancer. J. Endourol. 18(5), 495-500 (2004).
28. Johannsen M, Gneveckow U, Eckelt L et al.: Clinical hyperthermia of prostate cancer using magnetic nanoparticles: presentation of a new interstitial technique. Int. J. Hyperthermia 21(1), 1-11 (2005).
29. Jordan A, Scholza R, Maier-Hauff K et al.: Presentation of a new magnetic field therapy system for the treatment of human solid tumors with magnetic fluid hyperthermia. J. Magn. Magn. Mater. 225(1-2), 118-126 (2001).
30. Jordan A, Scholz R, Wust P et al.: Endocytosis of dextran and silan-coated magnetite nanoparticles and the effect of intracellular hyperthermia on human mammary carcinoma cell in vitro. J. Magn. Magn. Mater. 194, 185-196 (1999).
31. Jordan A, Scholz R, Wust P, Hähling H, Felix R: Magnetic fluid hyperthermia (MFH): cancer treatment with AC magnetic field induced excitation of biocompatible superparamagnetic nanoparticles. J. Magn. Magn. Mater. 201, 413-419 (1999).
32. Hergt R, Hiergeist R, Zeisberger M et al.: Enhancement of AC-losses of magnetic nanoparticles for heating applications. J. Magn. Magn. Mater. 280, 358-368 (2004).
33. Hergt R, Hiergeist R, Hilger I et al.: Maghemite nanoparticles with very high AC-losses for application in RF-magnetic hyperthermia. J. Magn. Magn. Mater. 270, 345-357 (2004).
34. Jordan A, Wust P, Scholz R et al.: Cellular uptake of magnetic fluid particles and their effects on human adenocarcinoma cells exposed to AC magnetic fields in vivo. Int. J. Hyperthermia 12, 705-722 (1996).
35. Jordan A, Scholz R, Wust P et al.: Effects of magnetic fluid hyperthermia (MFH) on C3H mammary carcinoma in vivo. Int. J. Hyperther. 13, 587-605 (1997).
36. Brunke O, Odenbach S, Jurgons R, Alexiou C, Hilger I, Beckmann F: Determination of the magnetic particle distribution in tumor tissue by means of x-ray tomography. J. Phys. Condens. Matter 18, S2903-S2917 (2006).
37. Brunke O, Odenbach S, Fritsche C et al.: Determination of magnetic particle distribution in biomedical applications by x-ray microtomography. J. Magn. Magn. Mater. 289, 2903-2917 (2005).
38. Rahn H, Gomez-Morilla I, Jurgons R, Alexiou Ch, Odenbach S: Micro computed tomography ana lysis of ferrofluids used for cancer treatment. J. Phys. Condens. Matter 20, 204152 (4pp) (2008).
39. Jurgons R, Seliger C, Hilpert A et al.: Drug loaded magnetic nanoparticles for cancer therapy. J. Phys. Condens. Matter 18(38), S2893-S2902 (2006).
40. Seliger CH, Jurgonsa R, Wiekhorst F et al.: In vitro investigation of the behaviour of magnetic particles by a circulating artery model. J. Magn. Magn. Mater. 311(1), 358-362 (2007).
41. Alexiou C, Arnold W, Klein RJ et al.: Locoregional cancer treatment with magnetic drug targeting. Cancer Res. 60(23), 6641-6648 (2000). ■■ Local cancer treatment: selective targeting of drugs into the respective tumor region.
42. Kidd JG, Rous PA: Transplantable rabbit carcinoma originating in a virus-induced papilloma and containing the virus in masked or altered form. J. Exp. Med. 71, 813-838 (1940).
43. Alexiou C, Jurgons R, Schmid RJ et al.: Magnetic drug targeting - biodistribution of the magnetic carrier and the chemotherapeutic agent mitoxantrone after locoregional cancer treatment. J. Drug Target. 11(3), 139-149 (2003).
44. Alexiou CH, Arnolda W, Hulin P et al.: Magnetic mitoxantrone nanoparticle detection by histology, x-ray and MRI after magnetic tumor targeting. J. Magn. Magn. Mater. 225(1-2), 187-193 (2001).
45. Alexiou C, Jurgons R, Schmid R et al.: Magnetic drug targeting - a new approach in locoregional tumor therapy with chemotherapeutic agents. Experimental animal studies. HNO 53(7), 618-622 (2005).
46. Alexiou C, Schmid RJ, Jurgons R et al.: Targeting cancer cells: magnetic nanoparticles as drug carriers. Eur. Biophys. J. 35, 446-450 (2006).
47. Alexiou C, Jurgons R, Seliger C, Iro H: Medical applications of magnetic nanoparticles. J. Nanosci. Nanotechnol. 6(9-10), 2762-2768 (2006).
48. Alexiou C, Jurgons R, Seliger C, Brunke O, Iro H, Odenbach S: Delivery of superparamagnetic nanoparticles for local chemotherapy after intraarterial infusion and magnetic drug targeting. Anticancer Res. 27(4A), 2019-2022 (2007).
49. Wiekhorst F, Seliger C, Jurgons R et al.: Quantification of magnetic nanoparticles by magnetorelaxometry and comparison to histology after magnetic drug targeting. J. Nanosci. Nanotechnol. 6(9-10), 3222-3225 (2006). ■ Proper comparison of a quantitative and semiquantitative technique to study the biodistribution of magnetic nanoparticles after magnetic drug targeting.
50. Rahn H, Gomez-Morilla I, Jurgons R, Alexiou CH, Eberbeck D, Odenbach S: Tomographic examinations of magnetic nanoparticles used as drug carriers. J. Magn. Magn. Mater. 321(10), 1517-1520 (2009).
51. Kim KG, Kim JH, Ryu JH, Min JH, Kim KW, Yoon K-H: Nano x-ray computed tomography system. Presented at: World Congress on Medical Physics and Biomedical Engineering. Seoul, Korea, 27 August-1 September 2007. ■ One of the publications representing the trend for nanoscale spatial resolution in microcomputed tomographic imaging.
52. Mayo S, Miller P, Gao D, Sheffield-Parker J: Software image alignment for x-ray microtomography with submicrometre resolution using a SEM-based x-ray microscope. J. Microscopy 228(3), 257-263 (2007).
53. Wang Y, de Carlo F. Foster I et al.: Quasi-real-time x-ray microtomography system at the advanced photon source. Proc. SPIE 3772, 318-327 (1999).
54. Ritman EL: Micro-computed tomography - current status and developments. Annu. Rev. Biomed. Eng. 6, 185-208 (2004). ■ Good overview of microtomographic imaging.
55. Schneider P, Stauber M, Voide R, Stampanoni M, Donahue LR, Müller R: Ultrastructural properties in cortical bone vary greatly in two inbred strains of mice as assessed by synchrotron light based micro- and nano-CT. J. Bone Miner. Res. 22, 1557-1570 (2007).
56. Eberbeck D, Bergemann CH, Wiekhosrt F, Steinhoff U, Trahms L: Quantification of specific bindings of biomolecules by magnetorelaxometry. J. Nanobiotechnol. 6, 4 (2008).
57. Ludwig F: Magnetorelaxometry of magnetic nanoparticles for the quantitative and specific analysis of biomolecules. Technisches Messen 73(4), 217-222 (2006).
58. Heim E, Harling S, Ludwig F, Menzel F, Schilling M: Fluxgate magnetorelaxometry for characterization of hydrogel polymerization kinetics and physical entrapment capacity. J. Phys. Condens. Matter 20, 204106 (5 pp) (2008).