Cellular uptake of magnetic fluid particles and their effects on human adenocarcinoma cells exposed to AC magnetic fields in vitro

International Journal of Hyperthermia

Volumn 12, Issue 6, 1996, Pages 705-722

  Jordan, A ^a   Wust, P ^a   Scholz, R ^a   Tesche, B ^b   Fahling H ^a   Mitrovics, T ^a   Vogl, T ^a   Cervos Navarro J ^a   Felix, R ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b MAX PLANCK INSTITUT FÜR KOHLENFORSCHUNG   (Germany)

Author keywords

Cancer therapy; Inductive heating; Interstitial; Magnetic fluid hyperthermia; Magnetic fluids

Indexed keywords

DEXTRAN MAGNETITE; FERRITE;

ABSORPTION; ADENOCARCINOMA; ARTICLE; BIOACCUMULATION; CARCINOMA CELL; CONTROLLED STUDY; ELECTRON MICROSCOPY; HUMAN; HUMAN CELL; HYPERTHERMIC THERAPY; MAGNETIC FIELD; SPECTROSCOPY; SUSPENDED PARTICULATE MATTER;

EID: 0029803597     PISSN: 02656736     EISSN: None     Source Type: Journal    
DOI: 10.3109/02656739609027678     Document Type: Article

References (32)

1. BORENFREUND, E., and BORRERO, O., 1984, In vitro cytotoxicity assays: potential alternatives to the draize occular irritancy test. Cell Biology and Toxicology, 1, 1-7.
2. CABUIL, V., NEVEU, S., and ROSENSWEIG, R. E., 1993, Introduction to the magnetic fluids bibliography (with bibliography 1989-1992), Journal of Magnetism and Magnetic Materials, Proceedings of the 6th International Conference on Magnetic Fluids, Vol. 122, edited by A. J. Freeman (North-Holland: Elsevier, pp. 439-482.
3. CHAN, D. C. F., KIRPOTIN, D. B., BAERJEE, A., and BUNN, P.A., 1992, The use of ferromagnetic colloids for radiofrequency induced ferromagnetic hyperthermia: in vitro studies. Proceedings of the 6th International Congress on Hyperthermic Oncology (ICHO) 367 pp.
4. CHAN, D. C. F., KIRPOTIN, D. B., and BUNN, P. A., 1993, Synthesis and evaluation of colloidal magnetic iron oxides for the site-specific radiofrequency-induced hyperthermia of cancer. Journal of Magnetism and Magnetic Materials, 122, 374-378.
5. FREEMAN, M. L., SPITZ, D. R., and MEREDITH, M. J., 1990, Does heat shock enhance oxidative stress? Studies with ferrous and ferric iron. Radiation Research, 124, 288-293.
6. GILCHRIST, R. K., MEDAL, R., SHOREY, W. D., HANSELMAN, R. C., PARROTT, J. C., and TAYLOR, C. B., 1957, Selective inductive heating of lymph nodes. Annals of Surgery, 146, 596-606.
7. GILCHRIST, R. K., SHOREY, W. D., HANSELMAN, R. C, DEPEYSTER, F. A., YANG, J., and MEDAL, R., 1965, Effects of electromagnetic heating on internal viscera: a preliminary to the treatment of human tumors. Annals of Surgery, 161, 890-896.
8. GORDON, R. T., 1988a, Treating cancer cells in vivo - by alteration electric and magnetic dipoles intracellularly by introduction of minute particles. US patent No. 4767611.
9. GORDON, R. T., 1988b. Diagnostic and therapeutic comparisons - containing metal transferrin dextran particles have high target cell selectively especially for treating cancer by inductive heating. US Patent No. 4735796.
10. GORDON, R. T., 1987a, Use of magnetic susceptibility probes in the treatment of cancer. US Patent No. 4662359.
11. GORDON, R. T., 1987b, Selective treatment of cancer cells - using minute particles which can be inductively heated as magnetic susceptibility probes. US Patent No. 4662359.
12. GORDON, R. T., HALPERIN, W. P., GORDON, D., and FREEMAN, A. J., 1986, Alterations in magnetic characteristics produced by intra-cellular particles. Journal of Biological Physics, 14, 77-79.
13. GORDON, R. T., 1980, Cancer-treating composition containing inductively-heatable particles. UK Patent Application 2024007.
14. GORDON, R. T., HINES, J. R., and GORDON, D., 1979, Intracellular hyperthermia. A biophysical approach to cancer treatment via intracellular temperature and biophysical alterations. Medical Hypothesis, 5, 83-102.
15. HARRISON, P. M., ARTYMIUK, P. J., FORD, G. C., LAWSON, D. M., SMITH, J. M. A., TREFFRY, A., and WHITE, J. L., 1989, Ferritin: funktion and structural design of an iron-storage protein, Biomineralization. Chemical and biochemical perspectives (Weinheim, Germany: VCH Verlagsgesellschaft), edited by S. Mann, J. Webb, R. J. P. Williams, pp. 257-259.
16. JORDAN, A., 1993, Magnetfeld-Ferrit-Hyperthermie (MFH): Physikalische und biologische Untersuchungen zur Evaluation von Magnetflüssigkeiten für die Behandlung maligner Geshwülste. Thesis of the Fachbereich Biologie (in German), Freie Universität Berlin, Berlin, Germany.
17. JORDAN, A., WUST, P., FÄHLING, H., JOHN, W., HINZ, A., and FELIX, R., 1993, Inductive heating of ferrimagnetic particles and magnetic fluids: physical evaluation of their potential for hyperthermia. International Journal of Hyperthermia, 9 (1), 51-68.
18. JOY, D. C., ROMIG, A. D., and GOLDSTEIN, J. I. (Eds), 1986, Principles of analytical electron microscopy, (Plenum Press: New York, London).
19. KOUICHIRO, O., TAKASHI, N., TAKAO, Y., MASAHIRO, H., MITSUYUKI, A., YUKIHIRO, E., TADASHI, K., and MASANORI, O., 1991, A bioactive, ferromagnetic glass-ceramic for hyperthermia. Materials in Sciences Monograph, 69, (Ceram. Substitutive Reconstr. Surg.) 131-136.
20. MELDRUM, F. C., HEYWOOD, B. R., and MANN, S., 1992, Magnetoferritin: in vitro synthesis of a novel magnetic protein. Science, 257, 522-523.
21. MITSUMORI, M., HIRAOKA, M., SHIBATA, T., OKUNO, Y., MASUNAGA, S., KOISHI, M., OKAJIMA, K., NAGATA, Y., NISHIMURA, Y., ABE, M., OHURA, K., HASEGAWA, M., NAGAE, H., and EBISAWA, Y., 1994, Development of intra-arterial hyperthermia using a dextran-magnetite complex. International Journal of Hyperthermia, 10 (6), 785-793.
22. MUIR, A. R., and GOLBERG, L., 1961, Observations on subcutaneous macrophages. Phagocytosis of iron-dextran and ferritin synthesis. Quarterly Journal of Experimental Physiology, 66 (4), 289-298.
23. PUCK, T. T, and MARCUS, P. I., 1955, A rapid method for viable cell titration and clone production with HeLa cells in tissue culture: the use of X-irradiated cells to supply conditioning factors. Proceedings of The National Academy of Sciences USA, 41, 432-437.
24. REAL, F. X., EGEA, G., FRANCI, C., SCHUSSLER, M. H., XU, M., WELT, S., 1991, Mucin production by colon cancer cells cultured in serum-free medium. International Journal of Cancer, 49, 787-795.
25. ROIZIN-TOWLE, L., and PIRRO, J., 1988, Thermotolerance in human cells of normal and neoplastic origin. International Journal of Hyperthermia, 4, 665-675.
26. SAKO, M., MORITA, M., OHTSUKI, S., ADACHI, S., WATANABE, H., HASEGAWA, M., SHIMIZU, T., IWASAWA, Y., OKUDA, K., FUJII, M., and KIMURA, S., 1984, Studies on selective embolohyperthermic therapy of tumours by using ferromagnetic particles. Journal of the National Japanese Society of Cancer Therapy, 2168-2171.
27. TAZAWA, K., TAKEMORI, S., YAMASHITA, I., SAITO, M., YAMAMOTO, K., KATO, H., KASAGI, T., SUZUKI, Y., MAEDA, M., and HONDA, T., 1987, Intracellular hyperthermia: effects of intracellular submicron particles exciting in induction field of 500 kHz (Meeting Abstract). Proceedings of the Annual Meeting of the Japan Cancer Association, 46, 498.
28. TAZAWA, K., TAKEMORI, S., NAGAE, H., YAMASHITA, I., KATO, H., OKAMOTO, M., KASAGI, T., MAEDA, M., HONDA, T., and FUJIMAKI, M., 1990, Intracellular hyperthermia by dextran magnetite (A biophysical approach to VX2 cancer), (meeting abstract), Proceedings of the Annual Meeting of the Japan Cancer Association, 49, 437.
29. TAZAWA, K., TAKEMORI, S., NAGAE, H., SHIMIZU, T., KATO, H., OKAMOTO, M., MASUKO, Y., MAEDA, M., and HONDA, T., 1992, A study of inductive heating for cancer with use of dextran magnetite (DM): characteristics of dextran magnetite. Proceedings of the 6th International Congress on Hyperthermic Oncology (ICHO), 153 pp.
30. TOMASOVIC, S. P., BARTA, M., and KLOSTERGAARD, J., 1989, Neutral red uptake and clonogenic survival assays of the hyperthermic sensitization of tumour cells to tumour necrosis factor. Radiation Research, 119, 325-337.
31. WUST, P., STAHL, H., LÖFFEL, J., SEEBASS, M., RIESS, H., and FELIX, R., 1995, Clinical, physiological and anatomical determinants for radiofrequency hyperthermia. International Journal of Hyperthermia, 11, 151-167.
32. YEH, T., ZHANG, W., ILDSTAD, S. T., and Ho, C., 1993, Intracellular labeling of T-cells with superparamagnetic contrast agents. Magnetic Resonance in Medicine, 30, 617-625.