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Volumn 81, Issue 5, 2009, Pages 956-965

Aromatase promoter I.f is regulated by estrogen receptor alpha (ESR1) in mouse hypothalamic neuronal cell lines

Author keywords

Aromatase; Brain; c Jun; Estradiol; Estradiol receptor; Estrogen receptor 1; Hypothalamus; Mechanisms of hormone action; Neuron; Promoter I.f

Indexed keywords

AROMATASE; ESTROGEN RECEPTOR ALPHA; MESSENGER RNA; MUTANT PROTEIN; NUCLEOTIDE; PROTEIN C JUN; TRANSCRIPTION FACTOR AP 1; ANTIESTROGEN; DRUG DERIVATIVE; ESTRADIOL; ESTROGEN; FULVESTRANT; PROTEIN C FOS; SMALL INTERFERING RNA;

EID: 73349116878     PISSN: 00063363     EISSN: 15297268     Source Type: Journal    
DOI: 10.1095/biolreprod.109.077206     Document Type: Article
Times cited : (43)

References (53)
  • 1
    • 0033005046 scopus 로고    scopus 로고
    • Estrogen and the developing mammalian brain
    • Beyer C. Estrogen and the developing mammalian brain. Anat Embryol (Berl) 1999; 199:379-390.
    • (1999) Anat Embryol (Berl) , vol.199 , pp. 379-390
    • Beyer, C.1
  • 2
    • 17444423677 scopus 로고    scopus 로고
    • Estrogen and brain: Synthesis, function and diseases
    • Li R, Shen Y. Estrogen and brain: synthesis, function and diseases. Front Biosci 2005; 10:257-267.
    • (2005) Front Biosci , vol.10 , pp. 257-267
    • Li, R.1    Shen, Y.2
  • 5
    • 0034749898 scopus 로고    scopus 로고
    • Minireview: Aromatase and the regulation of estrogen biosynthesis - some new perspectives
    • Simpson ER, Davis SR. Minireview: aromatase and the regulation of estrogen biosynthesis - some new perspectives. Endocrinology 2001; 142:4589-4594.
    • (2001) Endocrinology , vol.142 , pp. 4589-4594
    • Simpson, E.R.1    Davis, S.R.2
  • 7
    • 1942453880 scopus 로고    scopus 로고
    • Models of aromatase insufficiency
    • Simpson ER. Models of aromatase insufficiency. Semin Reprod Med 2004; 22:25-30.
    • (2004) Semin Reprod Med , vol.22 , pp. 25-30
    • Simpson, E.R.1
  • 9
    • 0037369735 scopus 로고    scopus 로고
    • Three different promoters control expression of the aromatase cytochrome p450 gene (cyp19) in mouse gonads and brain
    • Golovine K, Schwerin M, Vanselow J. Three different promoters control expression of the aromatase cytochrome p450 gene (cyp19) in mouse gonads and brain. Biol Reprod 2003; 68:978-984.
    • (2003) Biol Reprod , vol.68 , pp. 978-984
    • Golovine, K.1    Schwerin, M.2    Vanselow, J.3
  • 10
    • 0030051126 scopus 로고    scopus 로고
    • The alternative exons 1 of the mouse aromatase cytochrome P-450 gene
    • Honda S, Harada N, Takagi Y. The alternative exons 1 of the mouse aromatase cytochrome P-450 gene. Biochim Biophys Acta 1996; 1305:145-150.
    • (1996) Biochim Biophys Acta , vol.1305 , pp. 145-150
    • Honda, S.1    Harada, N.2    Takagi, Y.3
  • 11
    • 16244385227 scopus 로고    scopus 로고
    • National Center for Biotechnology Information, U.S. National Library of Medicine, Bethesda. Maryland. World Wide Web, February 2008
    • Basic Local Alignment Search Tool (BLAST), National Center for Biotechnology Information, U.S. National Library of Medicine, Bethesda. Maryland. World Wide Web (http://www.ncbi.nlm.nih.gov/BLAST/). (February 2008).
    • Basic Local Alignment Search Tool (BLAST)
  • 12
    • 0033586395 scopus 로고    scopus 로고
    • Identification of cis-acting elements in the proximal promoter region for brain-specific exon 1 of the mouse aromatase gene
    • Honda S, Harada N, Abe-Dohmae S, Takagi Y. Identification of cis-acting elements in the proximal promoter region for brain-specific exon 1 of the mouse aromatase gene. Brain Res Mol Brain Res 1999; 66:122-132.
    • (1999) Brain Res Mol Brain Res , vol.66 , pp. 122-132
    • Honda, S.1    Harada, N.2    Abe-Dohmae, S.3    Takagi, Y.4
  • 13
    • 0031120101 scopus 로고    scopus 로고
    • Molecular aspects of brain aromatase cytochrome P450
    • Lephart ED. Molecular aspects of brain aromatase cytochrome P450. J Steroid Biochem Mol Biol 1997; 61:375-380.
    • (1997) J Steroid Biochem Mol Biol , vol.61 , pp. 375-380
    • Lephart, E.D.1
  • 14
    • 0030174660 scopus 로고    scopus 로고
    • A review of brain aromatase cytochrome P450
    • Lephart ED. A review of brain aromatase cytochrome P450. Brain Res Brain Res Rev 1996; 22:1-26.
    • (1996) Brain Res Brain Res Rev , vol.22 , pp. 1-26
    • Lephart, E.D.1
  • 15
    • 26244450018 scopus 로고    scopus 로고
    • Aromatase is presynaptic and sexually dimorphic in the adult zebra finch brain
    • Peterson RS, Yarram L, Schlinger BA, Saldanha CJ. Aromatase is presynaptic and sexually dimorphic in the adult zebra finch brain. Proc Biol Sci 2005; 272:2089-2096.
    • (2005) Proc Biol Sci , vol.272 , pp. 2089-2096
    • Peterson, R.S.1    Yarram, L.2    Schlinger, B.A.3    Saldanha, C.J.4
  • 16
    • 33847355544 scopus 로고    scopus 로고
    • Neuroanatomical specificity of sex differences in expression of aromatase mRNA in the quail brain
    • Voigt C, Ball GF, Balthazart J. Neuroanatomical specificity of sex differences in expression of aromatase mRNA in the quail brain. J Chem Neuroanat 2007; 33:75-86.
    • (2007) J Chem Neuroanat , vol.33 , pp. 75-86
    • Voigt, C.1    Ball, G.F.2    Balthazart, J.3
  • 17
    • 33846945029 scopus 로고    scopus 로고
    • Region-specific expression and sex-steroidal regulation on aromatase and its mRNA in the male rat brain: Immunohistochemical and in situ hybridization analyses
    • Zhao C, Fujinaga R, Tanaka M, Yanai A, Nakahama K, Shinoda K. Region-specific expression and sex-steroidal regulation on aromatase and its mRNA in the male rat brain: immunohistochemical and in situ hybridization analyses. J Comp Neurol 2007; 500:557-573.
    • (2007) J Comp Neurol , vol.500 , pp. 557-573
    • Zhao, C.1    Fujinaga, R.2    Tanaka, M.3    Yanai, A.4    Nakahama, K.5    Shinoda, K.6
  • 18
    • 0032499704 scopus 로고    scopus 로고
    • Characterization of mice deficient in aromatase (ArKO) because of targeted disruption of the cyp19 gene
    • Fisher CR, Graves KH, Parlow AF, Simpson ER. Characterization of mice deficient in aromatase (ArKO) because of targeted disruption of the cyp19 gene. Proc Natl Acad Sci U S A 1998; 95:6965-6970.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 6965-6970
    • Fisher, C.R.1    Graves, K.H.2    Parlow, A.F.3    Simpson, E.R.4
  • 19
    • 2942521779 scopus 로고    scopus 로고
    • Relationships between aromatase activity in the brain and gonads and behavioural deficits in homozygous and heterozygous aromatase knockout mice
    • Bakker J, Baillien M, Honda S, Harada N, Balthazart J. Relationships between aromatase activity in the brain and gonads and behavioural deficits in homozygous and heterozygous aromatase knockout mice. J Neuroendocrinol 2004; 16:483-490.
    • (2004) J Neuroendocrinol , vol.16 , pp. 483-490
    • Bakker, J.1    Baillien, M.2    Honda, S.3    Harada, N.4    Balthazart, J.5
  • 20
    • 2942594757 scopus 로고    scopus 로고
    • Restoration of male sexual behavior by adult exogenous estrogens in male aromatase knockout mice
    • Bakker J, Honda S, Harada N, Balthazart J. Restoration of male sexual behavior by adult exogenous estrogens in male aromatase knockout mice. Horm Behav 2004; 46:1-10.
    • (2004) Horm Behav , vol.46 , pp. 1-10
    • Bakker, J.1    Honda, S.2    Harada, N.3    Balthazart, J.4
  • 21
    • 0035710923 scopus 로고    scopus 로고
    • Phosphorylation processes mediate rapid changes of brain aromatase activity
    • Balthazart J, Baillien M, Ball GF. Phosphorylation processes mediate rapid changes of brain aromatase activity. J Steroid Biochem Mol Biol 2001; 79:261-277.
    • (2001) J Steroid Biochem Mol Biol , vol.79 , pp. 261-277
    • Balthazart, J.1    Baillien, M.2    Ball, G.F.3
  • 22
    • 32044462486 scopus 로고    scopus 로고
    • Sex differences, developmental changes, response to injury and cAMP regulation of the mRNA levels of steroidogenic acute regulatory protein, cytochrome p450scc, and aromatase in the olivocerebellar system
    • Lavaque E, Mayen A, Azcoitia I, Tena-Sempere M, Garcia-Segura LM. Sex differences, developmental changes, response to injury and cAMP regulation of the mRNA levels of steroidogenic acute regulatory protein, cytochrome p450scc, and aromatase in the olivocerebellar system. J Neurobiol 2006; 66:308-318.
    • (2006) J Neurobiol , vol.66 , pp. 308-318
    • Lavaque, E.1    Mayen, A.2    Azcoitia, I.3    Tena-Sempere, M.4    Garcia-Segura, L.M.5
  • 24
    • 0027051421 scopus 로고
    • Brain aromatase cytochrome P-450 messenger RNA levels and enzyme activity during prenatal and perinatal development in the rat
    • Lephart ED, Simpson ER, McPhaul MJ, Kilgore MW, Wilson JD, Ojeda SR. Brain aromatase cytochrome P-450 messenger RNA levels and enzyme activity during prenatal and perinatal development in the rat. Brain Res Mol Brain Res 1992; 16:187-192.
    • (1992) Brain Res Mol Brain Res , vol.16 , pp. 187-192
    • Lephart, E.D.1    Simpson, E.R.2    McPhaul, M.J.3    Kilgore, M.W.4    Wilson, J.D.5    Ojeda, S.R.6
  • 25
    • 0035912873 scopus 로고    scopus 로고
    • Aromatase expression and activity in male and female cultured rat hypothalamic neurons: Effect of androgens
    • Negri-Cesi P, Colciago A, Motta M, Martini L, Celotti F. Aromatase expression and activity in male and female cultured rat hypothalamic neurons: effect of androgens. Mol Cell Endocrinol 2001; 178:1-10.
    • (2001) Mol Cell Endocrinol , vol.178 , pp. 1-10
    • Negri-Cesi, P.1    Colciago, A.2    Motta, M.3    Martini, L.4    Celotti, F.5
  • 26
    • 0030726669 scopus 로고    scopus 로고
    • Regulation of aromatase gene expression in the adult rat brain
    • Roselli CE, Abdelgadir SE, Resko JA. Regulation of aromatase gene expression in the adult rat brain. Brain Res Bull 1997; 44:351-357.
    • (1997) Brain Res Bull , vol.44 , pp. 351-357
    • Roselli, C.E.1    Abdelgadir, S.E.2    Resko, J.A.3
  • 28
    • 31144444671 scopus 로고    scopus 로고
    • Effects of estradiol on spatial learning, hippocampal cytochrome P450 19, and estrogen alpha and beta mRNA levels in ovariectomized female mice
    • Iivonen S, Heikkinen T, Puolivali J, Helisalmi S, Hiltunen M, Soininen H, Tanila H. Effects of estradiol on spatial learning, hippocampal cytochrome P450 19, and estrogen alpha and beta mRNA levels in ovariectomized female mice. Neuroscience 2006; 137:1143-1152.
    • (2006) Neuroscience , vol.137 , pp. 1143-1152
    • Iivonen, S.1    Heikkinen, T.2    Puolivali, J.3    Helisalmi, S.4    Hiltunen, M.5    Soininen, H.6    Tanila, H.7
  • 29
    • 0347717868 scopus 로고    scopus 로고
    • Generation of a phenotypic array of hypothalamic neuronal cell models to study complex neuroendocrine disorders
    • Belsham DD, Cai F, Cui H, Smukler SR, Salapatek AM, Shkreta L. Generation of a phenotypic array of hypothalamic neuronal cell models to study complex neuroendocrine disorders. Endocrinology 2004; 145:393-400.
    • (2004) Endocrinology , vol.145 , pp. 393-400
    • Belsham, D.D.1    Cai, F.2    Cui, H.3    Smukler, S.R.4    Salapatek, A.M.5    Shkreta, L.6
  • 32
    • 33749053405 scopus 로고    scopus 로고
    • SP1 and SP3 mediate progesterone-dependent induction of the 17beta hydroxysteroid dehydrogenase type 2 gene in human endometrium
    • Cheng YH, Imir A, Suzuki T, Fenkci V, Yilmaz B, Sasano H, Bulun SE. SP1 and SP3 mediate progesterone-dependent induction of the 17beta hydroxysteroid dehydrogenase type 2 gene in human endometrium. Biol Reprod 2006; 75:605-614.
    • (2006) Biol Reprod , vol.75 , pp. 605-614
    • Cheng, Y.H.1    Imir, A.2    Suzuki, T.3    Fenkci, V.4    Yilmaz, B.5    Sasano, H.6    Bulun, S.E.7
  • 33
    • 0035215015 scopus 로고    scopus 로고
    • Stromal PRs mediate induction of 17beta-hydroxysteroid dehydrogenase type 2 expression in human endometrial epithelium: A paracrine mechanism for inactivation of E2
    • Yang S, Fang Z, Gurates B, Tamura M, Miller J, Ferrer K, Bulun SE. Stromal PRs mediate induction of 17beta-hydroxysteroid dehydrogenase type 2 expression in human endometrial epithelium: a paracrine mechanism for inactivation of E2. Mol Endocrinol 2001; 15:2093-2105.
    • (2001) Mol Endocrinol , vol.15 , pp. 2093-2105
    • Yang, S.1    Fang, Z.2    Gurates, B.3    Tamura, M.4    Miller, J.5    Ferrer, K.6    Bulun, S.E.7
  • 34
  • 35
    • 33744928608 scopus 로고    scopus 로고
    • Role of the AP-1 transcription factor c-Jun in developing, adult and injured brain
    • Raivich G, Behrens A. Role of the AP-1 transcription factor c-Jun in developing, adult and injured brain. Prog Neurobiol 2006; 78:347-363.
    • (2006) Prog Neurobiol , vol.78 , pp. 347-363
    • Raivich, G.1    Behrens, A.2
  • 36
    • 0037109763 scopus 로고    scopus 로고
    • The aromatase knock-out mouse provides new evidence that estradiol is required during development in the female for the expression of sociosexual behaviors in adulthood
    • Bakker J, Honda S, Harada N, Balthazart J. The aromatase knock-out mouse provides new evidence that estradiol is required during development in the female for the expression of sociosexual behaviors in adulthood. J Neurosci 2002; 22:9104-9112.
    • (2002) J Neurosci , vol.22 , pp. 9104-9112
    • Bakker, J.1    Honda, S.2    Harada, N.3    Balthazart, J.4
  • 37
    • 1342287977 scopus 로고    scopus 로고
    • The aromatase knockout (ArKO) mouse provides new evidence that estrogens are required for the development of the female brain
    • Bakker J, Honda S, Harada N, Balthazart J. The aromatase knockout (ArKO) mouse provides new evidence that estrogens are required for the development of the female brain. Ann N Y Acad Sci 2003; 1007:251-262.
    • (2003) Ann N Y Acad Sci , vol.1007 , pp. 251-262
    • Bakker, J.1    Honda, S.2    Harada, N.3    Balthazart, J.4
  • 38
    • 0242626137 scopus 로고    scopus 로고
    • Neurological effects of aromatase deficiency in the mouse
    • Matsumoto T, Honda S, Harada N. Neurological effects of aromatase deficiency in the mouse. J Steroid Biochem Mol Biol 2003; 86:357-365.
    • (2003) J Steroid Biochem Mol Biol , vol.86 , pp. 357-365
    • Matsumoto, T.1    Honda, S.2    Harada, N.3
  • 39
    • 0038302043 scopus 로고    scopus 로고
    • Alteration in sex-specific behaviors in male mice lacking the aromatase gene
    • Matsumoto T, Honda S, Harada N. Alteration in sex-specific behaviors in male mice lacking the aromatase gene. Neuroendocrinology 2003; 77:416-424.
    • (2003) Neuroendocrinology , vol.77 , pp. 416-424
    • Matsumoto, T.1    Honda, S.2    Harada, N.3
  • 40
    • 33644552762 scopus 로고    scopus 로고
    • Roles of estrogen receptors alpha and beta in differentiation of mouse sexual behavior
    • Kudwa AE, Michopoulos V, Gatewood JD, Rissman EF. Roles of estrogen receptors alpha and beta in differentiation of mouse sexual behavior. Neuroscience 2006; 138:921-928.
    • (2006) Neuroscience , vol.138 , pp. 921-928
    • Kudwa, A.E.1    Michopoulos, V.2    Gatewood, J.D.3    Rissman, E.F.4
  • 41
    • 0031724077 scopus 로고    scopus 로고
    • Roles of estrogen receptor-alpha gene expression in reproduction-related behaviors in female mice
    • Ogawa S, Eng V, Taylor J, Lubahn DB, Korach KS, Pfaff DW. Roles of estrogen receptor-alpha gene expression in reproduction-related behaviors in female mice. Endocrinology 1998; 139:5070-5081.
    • (1998) Endocrinology , vol.139 , pp. 5070-5081
    • Ogawa, S.1    Eng, V.2    Taylor, J.3    Lubahn, D.B.4    Korach, K.S.5    Pfaff, D.W.6
  • 43
    • 34249277392 scopus 로고    scopus 로고
    • The ram as a model for behavioral neuroendocrinology
    • Perkins A, Roselli CE. The ram as a model for behavioral neuroendocrinology. Horm Behav 2007; 52:70-77.
    • (2007) Horm Behav , vol.52 , pp. 70-77
    • Perkins, A.1    Roselli, C.E.2
  • 44
    • 0023905889 scopus 로고
    • Changes in brain aromatase and 5 alpha-reductase activities correlate significantly with seasonal reproductive cycles in goldfish (Carassius auratus)
    • Pasmanik M, Callard GV. Changes in brain aromatase and 5 alpha-reductase activities correlate significantly with seasonal reproductive cycles in goldfish (Carassius auratus). Endocrinology 1988; 122:1349-1356.
    • (1988) Endocrinology , vol.122 , pp. 1349-1356
    • Pasmanik, M.1    Callard, G.V.2
  • 45
    • 0015579408 scopus 로고
    • Aromatization in the central nervous system of rabbits: Effects of castration and hormone treatment
    • Reddy VV, Naftolin F, Ryan KJ. Aromatization in the central nervous system of rabbits: effects of castration and hormone treatment. Endocrinology 1973; 92:589-594.
    • (1973) Endocrinology , vol.92 , pp. 589-594
    • Reddy, V.V.1    Naftolin, F.2    Ryan, K.J.3
  • 47
    • 0037275211 scopus 로고    scopus 로고
    • Para/autocrine regulation of estrogen receptors in hippocampal neurons
    • Prange-Kiel J, Wehrenberg U, Jarry H, Rune GM. Para/autocrine regulation of estrogen receptors in hippocampal neurons. Hippocampus 2003; 13:226-234.
    • (2003) Hippocampus , vol.13 , pp. 226-234
    • Prange-Kiel, J.1    Wehrenberg, U.2    Jarry, H.3    Rune, G.M.4
  • 48
    • 33646082698 scopus 로고    scopus 로고
    • Synaptic plasticity in the hippocampus: Effects of estrogen from the gonads or hippocampus?
    • Rune GM, Lohse C, Prange-Kiel J, Fester L, Frotscher M. Synaptic plasticity in the hippocampus: effects of estrogen from the gonads or hippocampus? Neurochem Res 2006; 31:145-155.
    • (2006) Neurochem Res , vol.31 , pp. 145-155
    • Rune, G.M.1    Lohse, C.2    Prange-Kiel, J.3    Fester, L.4    Frotscher, M.5
  • 49
    • 0037008453 scopus 로고    scopus 로고
    • Estrogen up-regulates estrogen receptor alpha and synaptophysin in slice cultures of rat hippocampus
    • Rune GM, Wehrenberg U, Prange-Kiel J, Zhou L, Adelmann G, Frotscher M. Estrogen up-regulates estrogen receptor alpha and synaptophysin in slice cultures of rat hippocampus. Neuroscience 2002; 113:167-175.
    • (2002) Neuroscience , vol.113 , pp. 167-175
    • Rune, G.M.1    Wehrenberg, U.2    Prange-Kiel, J.3    Zhou, L.4    Adelmann, G.5    Frotscher, M.6
  • 50
    • 28844450653 scopus 로고    scopus 로고
    • Neurosteroid synthesis in the hippocampus: Role in synaptic plasticity
    • Rune GM, Frotscher M. Neurosteroid synthesis in the hippocampus: role in synaptic plasticity. Neuroscience 2005; 136:833-842.
    • (2005) Neuroscience , vol.136 , pp. 833-842
    • Rune, G.M.1    Frotscher, M.2
  • 51
    • 0029099199 scopus 로고
    • Presence of estrogen receptors in aromatase-immunoreactive neurons in the mouse brain
    • Tsuruo Y, Ishimura K, Osawa Y. Presence of estrogen receptors in aromatase-immunoreactive neurons in the mouse brain. Neurosci Lett 1995; 195:49-52.
    • (1995) Neurosci Lett , vol.195 , pp. 49-52
    • Tsuruo, Y.1    Ishimura, K.2    Osawa, Y.3
  • 52
    • 33846425002 scopus 로고    scopus 로고
    • 0.2kb promoter sequence of the murine Cyp19 gene target beta-galactosidase expression to specific brain areas of transgenic mice
    • Nausch N, Manteuffel G, Vanselow J. 0.2kb promoter sequence of the murine Cyp19 gene target beta-galactosidase expression to specific brain areas of transgenic mice. J Steroid Biochem Mol Biol 2007; 103:119-128.
    • (2007) J Steroid Biochem Mol Biol , vol.103 , pp. 119-128
    • Nausch, N.1    Manteuffel, G.2    Vanselow, J.3


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