Incidence and risk factors for cardiovascular events and death in pediatric renal transplant patients: A single center long-term outcome study

Pediatric Transplantation

Volumn 13, Issue 8, 2009, Pages 1027-1033

  Koshy, Susan M ^a,b,c,d   Guttmann, Astrid ^a,c,d   Hebert, Diane ^a   Parkes, Robert K ^b   Logan, Alexander G ^b,d,e  

^a HOSPITAL FOR SICK CHILDREN   (Canada)

^b MOUNT SINAI HOSPITAL   (Canada)

^c SUNNYBROOK RESEARCH INSTITUTE   (Canada)

^d UNIVERSITY OF TORONTO   (Canada)

^e UNIVERSITY HEALTH NETWORK   (Canada)

Author keywords

Adolescents; Children; Diabetes; Kidney transplant; Longitudinal; Outcomes

Indexed keywords

AZATHIOPRINE; CYCLOSPORIN A; DACLIZUMAB; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; POLYCLONAL ANTIBODY; PREDNISONE; TACROLIMUS;

ADOLESCENT; ADULT; ARTICLE; CARDIOVASCULAR DISEASE; CARDIOVASCULAR RISK; CHILD; COHORT ANALYSIS; CONGESTIVE HEART FAILURE; CONTROLLED STUDY; DATA BASE; DIABETES MELLITUS; DISEASE ASSOCIATION; DISEASE COURSE; FEMALE; FOLLOW UP; GLOMERULUS FILTRATION RATE; HEALTH CARE SYSTEM; HEART ARREST; HEART DEATH; HEART INFARCTION; HUMAN; INCIDENCE; KIDNEY GRAFT REJECTION; KIDNEY TRANSPLANTATION; MAJOR CLINICAL STUDY; MALE; MEDICAL RECORD REVIEW; OUTCOME ASSESSMENT; PEDIATRIC SURGERY; PERIPHERAL VASCULAR DISEASE; POSTOPERATIVE COMPLICATION; RETROSPECTIVE STUDY; RISK FACTOR; SCHOOL CHILD; SURGICAL MORTALITY; TRANSIENT ISCHEMIC ATTACK;

ADOLESCENT; CARDIOVASCULAR DISEASES; CHILD; CONFIDENCE INTERVALS; FEMALE; HUMANS; IMMUNOSUPPRESSION; INCIDENCE; KIDNEY TRANSPLANTATION; LONGITUDINAL STUDIES; MALE; PREDICTIVE VALUE OF TESTS; RETROSPECTIVE STUDIES; RISK FACTORS; SURVIVAL RATE;

EID: 73349104422     PISSN: 13973142     EISSN: 13993046     Source Type: Journal    
DOI: 10.1111/j.1399-3046.2008.01111.x     Document Type: Article

References (29)

1. Bartosh SM, Leverson G, Robillard D, Sollinger HW. Long-term outcomes in pediatric renal transplant recipients who survive into adulthood. Transplantation 2003 : 76 : 1195 1200.
2. McDonald SP, Craig JC. Long-term survival of children with end-stage renal disease. N Engl J Med 2004 : 350 : 2654 2662.
3. Groothoff JW, Cransberg K, Offringa M, et al. Long-term follow-up of renal transplantation in children: A Dutch cohort study. Transplantation 2004 : 78 : 453 460.
4. Parekh RS, Carroll CE, Wolfe RA, Port FK. Cardiovascular mortality in children and young adults with end-stage kidney disease. J Pediatr 2002 : 141 : 191 197.
5. Statistics Canada. Downloaded from Statistics Canada website on May 16, 2007, http://www40.statcan.ca
6. Austin PC, Daly PA, Tu JV. A multicenter study of the coding accuracy of hospital discharge administrative data for patients admitted to cardiac care units in Ontario. Am Heart J 2002 : 144 : 290 296.
7. Tu JV, Austin PC, Filate WA, et al. Outcomes of acute myocardial infarction in Canada. Can J Cardiol 2003 : 19 : 893 901.
8. Faris PD, Grant FC, Galbraith PD, Gong Y, Ghali WA. Diagnostic cardiac catheterization and revascularization rates for coronary heart disease. Can J Cardiol 2004 : 20 : 391 397.
9. Jamal SM, Shrive FM, Ghali WA, Knudtson ML, Eisenberg MJ. In-hospital outcomes after percutaneous coronary intervention in Canada: 1992/93 to 2000/01. Can J Cardiol 2003 : 19 : 782 789.
10. Kokotailo RA, Hill MD. Coding of stroke and stroke risk factors using international classification of diseases, revisions 9 and 10. Stroke 2005 : 36 : 1776 1781.
11. Lee DS, Tran C, Flintoft V, Grant FC, Liu PP, Tu JV. CCORT/CCS quality indicators for congestive heart failure care. Can J Cardiol 2003 : 19 : 357 364. (Pubitemid 36603500)
12. Schwartz GJ, Haycock GB, Edelmann CM Jr., Spitzer A. A simple estimate of glomerular filtration rate in children derived from body length and plasma creatinine. Pediatrics 1976 : 58 : 259 263.
13. Schwartz GJ, Gauthier B. A simple estimate of glomerular filtration rate in adolescent boys. J Pediatr 1985 : 106 : 522 526.
14. Schwartz GJ, Feld LG, Langford DJ. A simple estimate of glomerular filtration rate in full-term infants during the first year of life. J Pediatr 1984 : 104 : 849 854.
15. Hux JE, Ivis F, Flintoft V, Bica A. Diabetes in Ontario: Determination of prevalence and incidence using a validated administrative data algorithm. Diabetes Care 2002 : 25 : 512 516.
16. Wijeysundera DN, Karkouti K, Dupuis JY, et al. Derivation and validation of a simplified predictive index for renal replacement therapy after cardiac surgery. JAMA 2007 : 297 : 1801 1809.
17. Statistics Canada. http://www40.statcan.ca, accessed date: Jan 17, 2008.
18. Hwang SW. Mortality among men using homeless shelters in Toronto, Ontario. JAMA 2000 : 283 : 2152 2157.
19. Cheung AM, Hwang SW. Risk of death among homeless women: A cohort study and review of the literature. CMAJ 2004 : 170 : 1243 1247.
20. Al-Uzri A, Stablein DM, R AC. Posttransplant diabetes mellitus in pediatric renal transplant recipients: A report of the North American Pediatric Renal Transplant Cooperative Study (NAPRTCS). Transplantation 2001 : 72 : 1020 1024.
21. Vanrenterghem YF, Claes K, Montagnino G, et al. Risk factors for cardiovascular events after successful renal transplantation. Transplantation 2008 : 85 : 209 216.
22. Wilkinson A, Davidson J, Dotta F, et al. Guidelines for the treatment and management of new-onset diabetes after transplantation. Clin Transplant 2005 : 19 : 291 298.
23. Benhamou PY, Penfornis A. Natural history, prognosis, and management of transplantation-induced diabetes mellitus. Diabetes Metab 2002 : 28 : 166 175.
24. Kasiske BL, Snyder JJ, Gilbertson D, Matas AJ. Diabetes mellitus after kidney transplantation in the United States. Am J Transplant 2003 : 3 : 178 185.
25. Imoagene-Oyedeji AE, Rosas SE, Doyle AM, Goral S, Bloom RD. Posttransplantation anemia at 12 months in kidney recipients treated with mycophenolate mofetil: Risk factors and implications for mortality. J Am Soc Nephrol 2006 : 17 : 3240 3247.
26. Meier-Kriesche HU, Baliga R, Kaplan B. Decreased renal function is a strong risk factor for cardiovascular death after renal transplantation. Transplantation 2003 : 75 : 1291 1295.
27. Kasiske BL, Chakkera HA, Roel J. Explained and unexplained ischemic heart disease risk after renal transplantation. J Am Soc Nephrol 2000 : 11 : 1735 1743.
28. Kasiske BL. Ischemic heart disease after renal transplantation. Kidney Int 2002 : 61 : 356 369.
29. Mitsnefes MM, Khoury PR, McEnery PT. Early posttransplantation hypertension and poor long-term renal allograft survival in pediatric patients. J Pediatr 2003 : 143 : 98 103.