Quinolone-resistant Salmonella Typhi in South Africa, 2003-2007

Epidemiology and Infection

Volumn 138, Issue 1, 2010, Pages 86-90

  Smith, A M ^a,b   Govender, N ^a   Keddy, K H ^a,b  

^a NATIONAL INSTITUTE FOR COMMUNICABLE DISEASES   (South Africa)

^b UNIVERSITY OF THE WITWATERSRAND   (South Africa)

Author keywords

Africa; Quinolone resistance; Salmonella typhi

Indexed keywords

CIPROFLOXACIN; DNA TOPOISOMERASE (ATP HYDROLYSING) A; DNA TOPOISOMERASE (ATP HYDROLYSING) B; NALIDIXIC ACID; PROTEIN PARC; PROTEIN PARE; QUINOLINE DERIVED ANTIINFECTIVE AGENT; DNA TOPOISOMERASE (ATP HYDROLYSING); DNA TOPOISOMERASE IV;

ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL CELL; BACTERIUM ISOLATE; CONTROLLED STUDY; GENE MUTATION; GENETIC VARIABILITY; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; POLYMERASE CHAIN REACTION; PULSED FIELD GEL ELECTROPHORESIS; SALMONELLA TYPHI; SOUTH AFRICA; TANDEM REPEAT; DRUG EFFECT; GENETICS; GENOTYPE; HUMAN; ISOLATION AND PURIFICATION; METABOLISM; MICROBIOLOGICAL EXAMINATION; MICROBIOLOGY; MULTIDRUG RESISTANCE; PHYSIOLOGY; PREVALENCE; TYPHOID FEVER;

CIPROFLOXACIN; DNA GYRASE; DNA TOPOISOMERASE IV; DRUG RESISTANCE, MULTIPLE, BACTERIAL; GENOTYPE; HUMANS; MICROBIAL SENSITIVITY TESTS; NALIDIXIC ACID; PREVALENCE; SALMONELLA TYPHI; SOUTH AFRICA; TYPHOID FEVER;

EID: 73349098216     PISSN: 09502688     EISSN: 14694409     Source Type: Journal    
DOI: 10.1017/S0950268809990331     Document Type: Article

References (15)

1. Crump JA, Luby SP, Mintz ED. The global burden of typhoid fever. Bulletin of the World Health Organisation 2004; 82: 346-353.
2. Aarestrup FM, et al. Is it time to change fluoroquinolone breakpoints for Salmonella spp.? Antimicrobial Agents and Chemotherapy 2003; 47: 827-829.
3. Jacoby GA. Mechanisms of resistance to quinolones. Clinical Infectious Diseases 2005; 41 (Suppl. 2): S120-S126.
4. Jacoby GA, Chow N, Waites KB. Prevalence of plasmid- mediated quinolone resistance. Antimicrobial Agents and Chemotherapy 2003; 47: 559-562.
5. Kariuki S, et al. Characterization of multidrug-resistant typhoid outbreaks in Kenya. Journal of Clinical Microbiology 2004; 42: 1477-1482.
6. Akinyemi KO, Coker AO. Trends of antibiotic resistance in Salmonella enterica serovar typhi isolated from hospitalized patients from 1997 to 2004 in Lagos, Nigeria. Indian Journal of Medical Microbiology 2007; 25: 436-437.
7. Nkemngu NJ, Asonganyi ED, Njunda AL. Treatment failure in a typhoid patient infected with nalidixic acid resistant S. enterica serovar Typhi with reduced susceptibility to ciprofloxacin: a case report from Cameroon. BMC Infectious Diseases 2005; 5: 49.
8. Liu Y, et al. Molecular typing of Salmonella enterica serovar typhi isolates from various countries in Asia by a multiplex PCR assay on variable-number tandem repeats. Journal of Clinical Microbiology 2003; 41: 4388-4394.
9. Eaves DJ, et al. Prevalence of mutations within the quinolone resistance-determining region of gyrA, gyrB, parC, and parE and association with antibiotic resistance in quinolone-resistant Salmonella enterica. Antimicrobial Agents and Chemotherapy 2004; 48: 4012-4015.
10. Jacoby GA, et al. qnrB, another plasmid-mediated gene for quinolone resistance. Antimicrobial Agents and Chemotherapy 2006; 50: 1178-1182.
11. Hopkins KL, et al. Plasmid-mediated quinolone resistance determinant qnrS1 found in Salmonella enterica strains isolated in the UK. Journal of Antimicrobial Chemotherapy 2007; 59: 1071-1075.
12. Baucheron S, et al. The AcrB multidrug transporter plays a major role in high-level fluoroquinolone resistance in Salmonella enterica serovar typhimurium phage type DT204. Microbial Drug Resistance 2002; 8: 281-289.
13. Baucheron S, et al. AcrAB-TolC directs efflux-mediated multidrug resistance in Salmonella enterica serovar typhimurium DT104. Antimicrobial Agents and Chemotherapy 2004; 48: 3729-3735.
14. Ling JM, et al. Mutations in topoisomerase genes of fluoroquinolone- resistant Salmonellae in Hong Kong. Antimicrobial Agents and Chemotherapy 2003; 47: 3567-3573.
15. Griggs DJ, Gensberg K, Piddock LJ. Mutations in gyrA gene of quinolone-resistant Salmonella serotypes isolated from humans and animals. Antimicrobial Agents and Chemotherapy 1996; 40: 1009-1013.