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Volumn 59, Issue 3, 2010, Pages 419-429

Hematopoietic progenitor kinase 1 is a critical component of prostaglandin E2-mediated suppression of the anti-tumor immune response

Author keywords

Immunosuppression; Lung cancer; Prostaglandin E2; T cell; Tumor immunology

Indexed keywords

CYCLOOXYGENASE 2 INHIBITOR; HEMATOPOIETIC PROGENITOR KINASE 1; INTERLEUKIN 2; PROSTAGLANDIN E2; PROTEIN SERINE THREONINE KINASE; SC 791; UNCLASSIFIED DRUG;

EID: 73349091816     PISSN: 03407004     EISSN: 14320851     Source Type: Journal    
DOI: 10.1007/s00262-009-0761-0     Document Type: Article
Times cited : (52)

References (43)
  • 1
    • 14844348835 scopus 로고    scopus 로고
    • Activation of hematopoietic progenitor kinase 1 involves relocation, autophosphorylation, and transphosphorylation by protein kinase D1
    • DOI 10.1128/MCB.25.6.2364-2383.2005
    • R Arnold IM Patzak B Neuhaus S Vancauwenbergh A Veillette J Van Lint F Kiefer 2005 Activation of hematopoietic progenitor kinase 1 involves relocation, autophosphorylation, and transphosphorylation by protein kinase D1 Mol Cell Biol 25 2364 2383 10.1128/MCB.25.6.2364-2383.2005 1:CAS:528:DC%2BD2MXisVOiur0%3D 15743830 (Pubitemid 40354631)
    • (2005) Molecular and Cellular Biology , vol.25 , Issue.6 , pp. 2364-2383
    • Arnold, R.1    Patzak, I.M.2    Neuhaus, B.3    Vancauwenbergh, S.4    Veillette, A.5    Van Lint, J.6    Kiefer, F.7
  • 2
    • 0027362823 scopus 로고
    • B70 antigen is a second ligand for CTLA-4 and CD28
    • DOI 10.1038/366076a0
    • M Azuma D Ito H Yagita K Okumura JH Phillips LL Lanier C Somoza 1993 B70 antigen is a second ligand for CTLA-4 and CD28 Nature 366 76 79 10.1038/366076a0 1:CAS:528:DyaK2cXivVymtQ%3D%3D 7694153 (Pubitemid 23345240)
    • (1993) Nature , vol.366 , Issue.6450 , pp. 76-79
    • Azuma, M.1    Ito, D.2    Yagita, H.3    Okumura, K.4    Phillips, J.H.5    Lanier, L.L.6    Somoza, C.7
  • 3
    • 0033233214 scopus 로고    scopus 로고
    • LPS and TNFα induce SOCS3 mRNA and inhibit IL-6-induced activation of STAT3 in macrophages
    • DOI 10.1016/S0014-5793(99)01662-2, PII S0014579399016622
    • JG Bode A Nimmesgern J Schmitz F Schaper M Schmitt W Frisch D Haussinger PC Heinrich L Graeve 1999 LPS and TNFalpha induce SOCS3 mRNA and inhibit IL-6-induced activation of STAT3 in macrophages FEBS Lett 463 365 370 10.1016/S0014-5793(99)01662-2 1:CAS:528:DyaK1MXnvFemtLo%3D 10606755 (Pubitemid 30001952)
    • (1999) FEBS Letters , vol.463 , Issue.3 , pp. 365-370
    • Bode, J.G.1    Nimmesgern, A.2    Schmitz, J.3    Schaper, F.4    Schmitt, M.5    Frisch, W.6    Haussinger, D.7    Heinrich, P.C.8    Graeve, L.9
  • 4
    • 37049019709 scopus 로고    scopus 로고
    • Caspase-cleaved HPK1 induces CD95L-independent activation-induced cell death in T and B lymphocytes
    • DOI 10.1182/blood-2007-01-071167
    • D Brenner A Golks M Becker W Muller CR Frey R Novak D Melamed F Kiefer PH Krammer R Arnold 2007 Caspase-cleaved HPK1 induces CD95L-independent activation-induced cell death in T and B lymphocytes Blood 110 3968 3977 10.1182/blood-2007-01-071167 1:CAS:528:DC%2BD2sXhtl2qsb7F 17712048 (Pubitemid 350248452)
    • (2007) Blood , vol.110 , Issue.12 , pp. 3968-3977
    • Brenner, D.1    Golks, A.2    Becker, M.3    Muller, W.4    Frey, C.R.5    Novak, R.6    Melamed, D.7    Kiefer, F.8    Krammer, P.H.9    Arnold, R.10
  • 5
    • 29244440885 scopus 로고    scopus 로고
    • Activation or suppression of NFκB by HPK1 determines sensitivity to activation-induced cell death
    • DOI 10.1038/sj.emboj.7600894
    • D Brenner A Golks F Kiefer PH Krammer R Arnold 2005 Activation or suppression of NFkappaB by HPK1 determines sensitivity to activation-induced cell death EMBO J 24 4279 4290 10.1038/sj.emboj.7600894 1:CAS:528: DC%2BD2MXhtlanu7zE 16341093 (Pubitemid 41828903)
    • (2005) EMBO Journal , vol.24 , Issue.24 , pp. 4279-4290
    • Brenner, D.1    Golks, A.2    Kiefer, F.3    Krammer, P.H.4    Arnold, R.5
  • 6
    • 33747028253 scopus 로고    scopus 로고
    • Mediators of PGE2 synthesis and signalling downstream of COX-2 represent potential targets for the prevention/treatment of colorectal cancer
    • 1:CAS:528:DC%2BD28XotVyru74%3D 16859832
    • S Chell A Kaidi AC Williams C Paraskeva 2006 Mediators of PGE2 synthesis and signalling downstream of COX-2 represent potential targets for the prevention/treatment of colorectal cancer Biochim Biophys Acta 1766 104 119 1:CAS:528:DC%2BD28XotVyru74%3D 16859832
    • (2006) Biochim Biophys Acta , vol.1766 , pp. 104-119
    • Chell, S.1    Kaidi, A.2    Williams, A.C.3    Paraskeva, C.4
  • 7
    • 34147150656 scopus 로고    scopus 로고
    • Ablation of Cbl-b provides protection against transplanted and spontaneous tumors
    • DOI 10.1172/JCI29472
    • JY Chiang IK Jang R Hodes H Gu 2007 Ablation of Cbl-b provides protection against transplanted and spontaneous tumors J Clin Invest 117 1029 1036 10.1172/JCI29472 1:CAS:528:DC%2BD2sXktVOitrc%3D 17364027 (Pubitemid 46556759)
    • (2007) Journal of Clinical Investigation , vol.117 , Issue.4 , pp. 1029-1036
    • Chiang, J.Y.1    Ihn, K.J.2    Hodes, R.3    Gu, H.4
  • 8
    • 0022385214 scopus 로고
    • Prostaglandin E2 acts at two distinct pathways of T-lymphocyte activation: Inhibition of interleukin 2 production and down-regulation of transferrin receptor expression
    • 1:CAS:528:DyaL2MXltFKqurw%3D 2989362
    • S Chouaib K Welte R Mertelsmann B Dupont 1985 Prostaglandin E2 acts at two distinct pathways of T-lymphocyte activation: inhibition of interleukin 2 production and down-regulation of transferrin receptor expression J Immunol 135 1172 1179 1:CAS:528:DyaL2MXltFKqurw%3D 2989362
    • (1985) J Immunol , vol.135 , pp. 1172-1179
    • Chouaib, S.1    Welte, K.2    Mertelsmann, R.3    Dupont, B.4
  • 9
    • 4143141823 scopus 로고    scopus 로고
    • The immunobiology of cancer immunosurveillance and immunoediting
    • DOI 10.1016/j.immuni.2004.07.017, PII S1074761304002092
    • GP Dunn LJ Old RD Schreiber 2004 The immunobiology of cancer immunosurveillance and immunoediting Immunity 21 137 148 10.1016/j.immuni.2004. 07.017 1:CAS:528:DC%2BD2cXnsVKltrY%3D 15308095 (Pubitemid 39094044)
    • (2004) Immunity , vol.21 , Issue.2 , pp. 137-148
    • Dunn, G.P.1    Old, L.J.2    Schreiber, R.D.3
  • 10
    • 0017658218 scopus 로고
    • Suppression of human T-cell mitogenesis by prostaglandin. Existence of a prostaglandin-producing suppressor cell
    • 10.1084/jem.146.6.1719 1:CAS:528:DyaE1cXksFeguw%3D%3D 411876
    • JS Goodwin AD Bankhurst RP Messner 1977 Suppression of human T-cell mitogenesis by prostaglandin. Existence of a prostaglandin-producing suppressor cell J Exp Med 146 1719 1734 10.1084/jem.146.6.1719 1:CAS:528: DyaE1cXksFeguw%3D%3D 411876
    • (1977) J Exp Med , vol.146 , pp. 1719-1734
    • Goodwin, J.S.1    Bankhurst, A.D.2    Messner, R.P.3
  • 12
    • 0034646688 scopus 로고    scopus 로고
    • The cyclooxygenase-2 inhibitor celecoxib induces apoptosis by blocking Akt activation in human prostate cancer cells independently of Bcl-2
    • DOI 10.1074/jbc.275.15.11397
    • AL Hsu TT Ching DS Wang X Song VM Rangnekar CS Chen 2000 The cyclooxygenase-2 inhibitor celecoxib induces apoptosis by blocking Akt activation in human prostate cancer cells independently of Bcl-2 J Biol Chem 275 11397 11403 10.1074/jbc.275.15.11397 1:CAS:528:DC%2BD3cXislShu70%3D 10753955 (Pubitemid 30212792)
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.15 , pp. 11397-11403
    • Hsu, A.-L.1    Ching, T.-T.2    Wang, D.-S.3    Song, X.4    Rangnekar, V.M.5    Chen, C.-S.6
  • 13
    • 0032521401 scopus 로고    scopus 로고
    • Non-small cell lung cancer cyclooxygenase-2-dependent regulation of cytokine balance in lymphocytes and macrophages: Up-regulation of interleukin 10 and down-regulation of interleukin 12 production
    • 1:CAS:528:DyaK1cXhvV2rs7w%3D 9515807
    • M Huang M Stolina S Sharma JT Mao L Zhu PW Miller J Wollman H Herschman SM Dubinett 1998 Non-small cell lung cancer cyclooxygenase-2-dependent regulation of cytokine balance in lymphocytes and macrophages: up-regulation of interleukin 10 and down-regulation of interleukin 12 production Cancer Res 58 1208 1216 1:CAS:528:DyaK1cXhvV2rs7w%3D 9515807
    • (1998) Cancer Res , vol.58 , pp. 1208-1216
    • Huang, M.1    Stolina, M.2    Sharma, S.3    Mao, J.T.4    Zhu, L.5    Miller, P.W.6    Wollman, J.7    Herschman, H.8    Dubinett, S.M.9
  • 14
    • 0037126021 scopus 로고    scopus 로고
    • Involvement of PD-L1 on tumor cells in the escape from host immune system and tumor immunotherapy by PD-L1 blockade
    • 10.1073/pnas.192461099 1:CAS:528:DC%2BD38XntlCksL8%3D 12218188
    • Y Iwai M Ishida Y Tanaka T Okazaki T Honjo N Minato 2002 Involvement of PD-L1 on tumor cells in the escape from host immune system and tumor immunotherapy by PD-L1 blockade Proc Natl Acad Sci USA 99 12293 12297 10.1073/pnas.192461099 1:CAS:528:DC%2BD38XntlCksL8%3D 12218188
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 12293-12297
    • Iwai, Y.1    Ishida, M.2    Tanaka, Y.3    Okazaki, T.4    Honjo, T.5    Minato, N.6
  • 16
    • 33744471666 scopus 로고    scopus 로고
    • The potential and rationale for COX-2 inhibitors in lung cancer
    • 10.2174/187152006776930882 1:CAS:528:DC%2BD28XkvFKkur8%3D 16712449
    • K Krysan KL Reckamp S Sharma SM Dubinett 2006 The potential and rationale for COX-2 inhibitors in lung cancer Anticancer Agents Med Chem 6 209 220 10.2174/187152006776930882 1:CAS:528:DC%2BD28XkvFKkur8%3D 16712449
    • (2006) Anticancer Agents Med Chem , vol.6 , pp. 209-220
    • Krysan, K.1    Reckamp, K.L.2    Sharma, S.3    Dubinett, S.M.4
  • 17
    • 2442461214 scopus 로고    scopus 로고
    • Recruitment of the Actin-binding Protein HIP-55 to the Immunological Synapse Regulates T Cell Receptor Signaling and Endocytosis
    • DOI 10.1074/jbc.M312659200
    • S Le Bras I Foucault A Foussat C Brignone O Acuto M Deckert 2004 Recruitment of the actin-binding protein HIP-55 to the immunological synapse regulates T cell receptor signaling and endocytosis J Biol Chem 279 15550 15560 10.1074/jbc.M312659200 1:CAS:528:DC%2BD2cXivVKgt7k%3D 14729663 (Pubitemid 38618956)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.15 , pp. 15550-15560
    • Le Bras, S.1    Foucault, I.2    Foussat, A.3    Brignone, C.4    Acuto, O.5    Deckert, M.6
  • 18
    • 0029947568 scopus 로고    scopus 로고
    • Enhancement of antitumor immunity by CTLA-4 blockade
    • 10.1126/science.271.5256.1734 1:CAS:528:DyaK28XhvVWmsLk%3D 8596936
    • DR Leach MF Krummel JP Allison 1996 Enhancement of antitumor immunity by CTLA-4 blockade Science 271 1734 1736 10.1126/science.271.5256.1734 1:CAS:528:DyaK28XhvVWmsLk%3D 8596936
    • (1996) Science , vol.271 , pp. 1734-1736
    • Leach, D.R.1    Krummel, M.F.2    Allison, J.P.3
  • 19
    • 0033711185 scopus 로고    scopus 로고
    • HPK1 is activated by lymphocyte antigen receptors and negatively regulates AP-1
    • 10.1016/S1074-7613(00)80192-2 1:CAS:528:DC%2BD3cXivFyrsb0%3D 10795738
    • J Liou F Kiefer A Dang A Hashimoto MH Cobb T Kurosaki A Weiss 2000 HPK1 is activated by lymphocyte antigen receptors and negatively regulates AP-1 Immunity 12 399 408 10.1016/S1074-7613(00)80192-2 1:CAS:528:DC%2BD3cXivFyrsb0%3D 10795738
    • (2000) Immunity , vol.12 , pp. 399-408
    • Liou, J.1    Kiefer, F.2    Dang, A.3    Hashimoto, A.4    Cobb, M.H.5    Kurosaki, T.6    Weiss, A.7
  • 20
    • 0035947709 scopus 로고    scopus 로고
    • Overexpression of cyclooxygenase-2 is sufficient to induce tumorigenesis in transgenic mice
    • 10.1074/jbc.M010787200 1:CAS:528:DC%2BD3MXktFWmtbc%3D 11278747
    • CH Liu SH Chang K Narko OC Trifan MT Wu E Smith C Haudenschild TF Lane T Hla 2001 Overexpression of cyclooxygenase-2 is sufficient to induce tumorigenesis in transgenic mice J Biol Chem 276 18563 18569 10.1074/jbc.M010787200 1:CAS:528:DC%2BD3MXktFWmtbc%3D 11278747
    • (2001) J Biol Chem , vol.276 , pp. 18563-18569
    • Liu, C.H.1    Chang, S.H.2    Narko, K.3    Trifan, O.C.4    Wu, M.T.5    Smith, E.6    Haudenschild, C.7    Lane, T.F.8    Hla, T.9
  • 22
    • 0021894586 scopus 로고
    • Prostaglandin E2 inhibits the activation of cloned T cell hybridomas
    • 1:CAS:528:DyaL2MXhs1Wit74%3D 2857750
    • GT Makoul DR Robinson AK Bhalla LH Glimcher 1985 Prostaglandin E2 inhibits the activation of cloned T cell hybridomas J Immunol 134 2645 2650 1:CAS:528:DyaL2MXhs1Wit74%3D 2857750
    • (1985) J Immunol , vol.134 , pp. 2645-2650
    • Makoul, G.T.1    Robinson, D.R.2    Bhalla, A.K.3    Glimcher, L.H.4
  • 23
    • 0028326766 scopus 로고
    • CTL induction by a tumour-associated antigen octapeptide derived from a murine lung carcinoma
    • DOI 10.1038/369067a0
    • O Mandelboim G Berke M Fridkin M Feldman M Eisenstein L Eisenbach 1994 CTL induction by a tumour-associated antigen octapeptide derived from a murine lung carcinoma Nature 369 67 71 10.1038/369067a0 1:STN:280:DyaK2c3hslyisw%3D%3D 8164742 (Pubitemid 24144356)
    • (1994) Nature , vol.369 , Issue.6475 , pp. 67-71
    • Mandelbolm, O.1    Berke, G.2    Fridkin, M.3    Feldman, M.4    Eisenstein, M.5    Eisenbach, L.6
  • 25
    • 0025024913 scopus 로고
    • Agents that elevate cAMP stimulate DNA fragmentation in thymocytes
    • 1:CAS:528:DyaK3cXlslSht78%3D 2166110
    • DJ McConkey S Orrenius M Jondal 1990 Agents that elevate cAMP stimulate DNA fragmentation in thymocytes J Immunol 145 1227 1230 1:CAS:528: DyaK3cXlslSht78%3D 2166110
    • (1990) J Immunol , vol.145 , pp. 1227-1230
    • McConkey, D.J.1    Orrenius, S.2    Jondal, M.3
  • 26
    • 0034783581 scopus 로고    scopus 로고
    • Receptors for prostaglandin E2 that regulate cellular immune responses in the mouse
    • 1:CAS:528:DC%2BD3MXns1ChsLk%3D 11602631
    • C Nataraj DW Thomas SL Tilley M Nguyen R Mannon BH Koller TM Coffman 2001 Receptors for prostaglandin E2 that regulate cellular immune responses in the mouse J Clin Invest 108 1229 1235 1:CAS:528:DC%2BD3MXns1ChsLk%3D 11602631
    • (2001) J Clin Invest , vol.108 , pp. 1229-1235
    • Nataraj, C.1    Thomas, D.W.2    Tilley, S.L.3    Nguyen, M.4    Mannon, R.5    Koller, B.H.6    Coffman, T.M.7
  • 27
    • 0028845788 scopus 로고
    • Molecular mechanisms of diverse actions of prostanoid receptors
    • 10.1016/0005-2760(95)00146-4
    • M Negishi Y Sugimoto A Ichikawa 1995 Molecular mechanisms of diverse actions of prostanoid receptors Biochim Biophys Acta (BBA)-Lipids Lipid Metab 1259 109 119 10.1016/0005-2760(95)00146-4
    • (1995) Biochim Biophys Acta (BBA)-Lipids Lipid Metab , vol.1259 , pp. 109-119
    • Negishi, M.1    Sugimoto, Y.2    Ichikawa, A.3
  • 28
    • 0027331414 scopus 로고
    • 2 and other cyclic AMP elevating agents inhibit interleukin 2 gene transcription by counteracting calcineurin-dependent pathways
    • DOI 10.1084/jem.178.5.1813
    • F Paliogianni RL Kincaid DT Boumpas 1993 Prostaglandin E2 and other cyclic AMP elevating agents inhibit interleukin 2 gene transcription by counteracting calcineurin-dependent pathways J Exp Med 178 1813 1817 10.1084/jem.178.5.1813 1:CAS:528:DyaK3sXlvFKntbY%3D 7693857 (Pubitemid 23318463)
    • (1993) Journal of Experimental Medicine , vol.178 , Issue.5 , pp. 1813-1817
    • Paliogianni, F.1    Kincaid, R.L.2    Boumpas, D.T.3
  • 29
    • 0030302508 scopus 로고    scopus 로고
    • Prostaglandin E2 induces apoptosis in resting immature and mature human lymphocytes: A c-Myc-dependent and Bcl-2-independent associated pathway
    • 1:CAS:528:DyaK28XjslGksrY%3D 8667251
    • F Pica O Franzese C D'Onofrio E Bonmassar C Favalli E Garaci 1996 Prostaglandin E2 induces apoptosis in resting immature and mature human lymphocytes: a c-Myc-dependent and Bcl-2-independent associated pathway J Pharmacol Exp Ther 277 1793 1800 1:CAS:528:DyaK28XjslGksrY%3D 8667251
    • (1996) J Pharmacol Exp Ther , vol.277 , pp. 1793-1800
    • Pica, F.1    Franzese, O.2    D'Onofrio, C.3    Bonmassar, E.4    Favalli, C.5    Garaci, E.6
  • 30
    • 33745851479 scopus 로고    scopus 로고
    • CTLA4 blockade and GM-CSF combination immunotherapy alters the intratumor balance of effector and regulatory T cells
    • DOI 10.1172/JCI27745
    • SA Quezada KS Peggs MA Curran JP Allison 2006 CTLA4 blockade and GM-CSF combination immunotherapy alters the intratumor balance of effector and regulatory T cells J Clin Invest 116 1935 1945 10.1172/JCI27745 1:CAS:528:DC%2BD28XmvV2lurw%3D 16778987 (Pubitemid 44033317)
    • (2006) Journal of Clinical Investigation , vol.116 , Issue.7 , pp. 1935-1945
    • Quezada, S.A.1    Peggs, K.S.2    Curran, M.A.3    Allison, J.P.4
  • 31
    • 0020061358 scopus 로고
    • Prostaglandin e inhibits the production of human interleukin 2
    • 10.1084/jem.155.3.943 1:CAS:528:DyaL38XhtlKrtrw%3D 6977613
    • RS Rappaport GR Dodge 1982 Prostaglandin E inhibits the production of human interleukin 2 J Exp Med 155 943 948 10.1084/jem.155.3.943 1:CAS:528:DyaL38XhtlKrtrw%3D 6977613
    • (1982) J Exp Med , vol.155 , pp. 943-948
    • Rappaport, R.S.1    Dodge, G.R.2
  • 32
    • 0035976905 scopus 로고    scopus 로고
    • Hematopoietic progenitor kinase 1 associates physically and functionally with the adaptor proteins B cell linker protein and SLP-76 in lymphocytes
    • 10.1074/jbc.M106811200 1:CAS:528:DC%2BD3MXovFensLY%3D 11487585
    • K Sauer J Liou SB Singh D Yablonski A Weiss RM Perlmutter 2001 Hematopoietic progenitor kinase 1 associates physically and functionally with the adaptor proteins B cell linker protein and SLP-76 in lymphocytes J Biol Chem 276 45207 45216 10.1074/jbc.M106811200 1:CAS:528:DC%2BD3MXovFensLY%3D 11487585
    • (2001) J Biol Chem , vol.276 , pp. 45207-45216
    • Sauer, K.1    Liou, J.2    Singh, S.B.3    Yablonski, D.4    Weiss, A.5    Perlmutter, R.M.6
  • 33
    • 36849085818 scopus 로고    scopus 로고
    • 2 activates HPK1 kinase activity via a PKA-dependent pathway
    • DOI 10.1074/jbc.M707425200
    • S Sawasdikosol S Pyarajan S Alzabin G Matejovic SJ Burakoff 2007 Prostaglandin E2 activates HPK1 kinase activity via a PKA-dependent pathway J Biol Chem 282 34693 34699 10.1074/jbc.M707425200 1:CAS:528:DC%2BD2sXhtlCrtrjL 17895239 (Pubitemid 350232471)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.48 , pp. 34693-34699
    • Sawasdikosol, S.1    Pyarajan, S.2    Alzabin, S.3    Matejovic, G.4    Burakoff, S.J.5
  • 34
    • 0038542822 scopus 로고    scopus 로고
    • 2-induced fos gene transcription
    • DOI 10.1182/blood-2002-07-2316
    • S Sawasdikosol KM Russo SJ Burakoff 2003 Hematopoietic progenitor kinase 1 (HPK1) negatively regulates prostaglandin E2-induced fos gene transcription Blood 101 3687 3689 10.1182/blood-2002-07-2316 1:CAS:528:DC%2BD3sXjs1aqt7k%3D 12522005 (Pubitemid 36857960)
    • (2003) Blood , vol.101 , Issue.9 , pp. 3687-3689
    • Sawasdikosol, S.1    Russo, K.M.2    Burakoff, S.J.3
  • 35
    • 0024405219 scopus 로고
    • Regulation of monokine gene expression: Prostaglandin E2 suppresses tumor necrosis factor but not interleukin-1 alpha or beta-mRNA and cell-associated bioactivity
    • 1:CAS:528:DyaL1MXktVWnt7s%3D 2651547
    • WE Scales SW Chensue I Otterness SL Kunkel 1989 Regulation of monokine gene expression: prostaglandin E2 suppresses tumor necrosis factor but not interleukin-1 alpha or beta-mRNA and cell-associated bioactivity J Leukoc Biol 45 416 421 1:CAS:528:DyaL1MXktVWnt7s%3D 2651547
    • (1989) J Leukoc Biol , vol.45 , pp. 416-421
    • Scales, W.E.1    Chensue, S.W.2    Otterness, I.3    Kunkel, S.L.4
  • 36
    • 0036682941 scopus 로고    scopus 로고
    • Hematopoietic progenitor kinase 1 supports apoptosis of T lymphocytes
    • DOI 10.1182/blood-2002-01-0089
    • J Schulze-Luehrmann B Santner-Nanan MK Jha A Schimpl A Avots E Serfling 2002 Hematopoietic progenitor kinase 1 supports apoptosis of T lymphocytes Blood 100 954 960 10.1182/blood-2002-01-0089 1:CAS:528:DC%2BD38XlvVCltb4%3D 12130508 (Pubitemid 34832623)
    • (2002) Blood , vol.100 , Issue.3 , pp. 954-960
    • Schulze-Luehrmann, J.1    Santner-Nanan, B.2    Jha, M.K.3    Schimpl, A.4    Avots, A.5    Serfling, E.6
  • 37
    • 1842837878 scopus 로고    scopus 로고
    • Cyclooxygenase 2-dependent regulation of antitumor immunity in lung cancer
    • 1:CAS:528:DC%2BD38XovVWksb0%3D 12407775
    • S Sharma M Huang M Dohadwala M Pold RK Batra SM Dubinett 2003 Cyclooxygenase 2-dependent regulation of antitumor immunity in lung cancer Methods Mol Med 75 723 736 1:CAS:528:DC%2BD38XovVWksb0%3D 12407775
    • (2003) Methods Mol Med , vol.75 , pp. 723-736
    • Sharma, S.1    Huang, M.2    Dohadwala, M.3    Pold, M.4    Batra, R.K.5    Dubinett, S.M.6
  • 38
    • 33846969931 scopus 로고    scopus 로고
    • Hematopoietic progenitor kinase 1 negatively regulates T cell receptor signaling and T cell-mediated immune responses
    • DOI 10.1038/ni1416, PII NI1416
    • JW Shui JS Boomer J Han J Xu GA Dement G Zhou TH Tan 2007 Hematopoietic progenitor kinase 1 negatively regulates T cell receptor signaling and T cell-mediated immune responses Nat Immunol 8 84 91 10.1038/ni1416 1:CAS:528:DC%2BD28XhtlaqsL7P 17115060 (Pubitemid 46242362)
    • (2007) Nature Immunology , vol.8 , Issue.1 , pp. 84-91
    • Shui, J.-W.1    Boomer, J.S.2    Han, J.3    Xu, J.4    Dement, G.A.5    Zhou, G.6    Tan, T.-H.7
  • 40
    • 0028109394 scopus 로고
    • 2
    • DOI 10.1084/jem.180.6.2365
    • G Strassmann V Patil-Koota F Finkelman M Fong T Kambayashi 1994 Evidence for the involvement of interleukin 10 in the differential deactivation of murine peritoneal macrophages by prostaglandin E2 J Exp Med 180 2365 2370 10.1084/jem.180.6.2365 1:CAS:528:DyaK2cXmsVKqtrk%3D 7525853 (Pubitemid 24351620)
    • (1994) Journal of Experimental Medicine , vol.180 , Issue.6 , pp. 2365-2370
    • Strassmann, G.1    Patil-Koota, V.2    Finkelman, F.3    Fong, M.4    Kambayashi, T.5
  • 41
    • 0025731576 scopus 로고
    • Modulation of thymocyte apoptosis by isoproterenol and prostaglandin E2
    • 10.1016/0008-8749(91)90346-D 1:CAS:528:DyaK3MXltFamtb4%3D 1849462
    • K Suzuki T Tadakuma H Kizaki 1991 Modulation of thymocyte apoptosis by isoproterenol and prostaglandin E2 Cell Immunol 134 235 240 10.1016/0008- 8749(91)90346-D 1:CAS:528:DyaK3MXltFamtb4%3D 1849462
    • (1991) Cell Immunol , vol.134 , pp. 235-240
    • Suzuki, K.1    Tadakuma, T.2    Kizaki, H.3
  • 42
    • 0028803728 scopus 로고
    • Alterations in cellular adhesion and apoptosis in epithelial cells overexpressing prostaglandin endoperoxide synthase 2
    • 10.1016/0092-8674(95)90127-2 1:CAS:528:DyaK2MXpt1Olt7w%3D 8521479
    • M Tsujii RN DuBois 1995 Alterations in cellular adhesion and apoptosis in epithelial cells overexpressing prostaglandin endoperoxide synthase 2 Cell 83 493 501 10.1016/0092-8674(95)90127-2 1:CAS:528:DyaK2MXpt1Olt7w%3D 8521479
    • (1995) Cell , vol.83 , pp. 493-501
    • Tsujii, M.1    Dubois, R.N.2
  • 43
    • 0003504049 scopus 로고    scopus 로고
    • Cyclooxygenase regulates angiogenesis induced by colon cancer cells
    • DOI 10.1016/S0092-8674(00)81433-6
    • M Tsujii S Kawano S Tsuji H Sawaoka M Hori RN DuBois 1998 Cyclooxygenase regulates angiogenesis induced by colon cancer cells Cell 93 705 716 10.1016/S0092-8674(00)81433-6 1:CAS:528:DyaK1cXjsl2ksbw%3D 9630216 (Pubitemid 28257578)
    • (1998) Cell , vol.93 , Issue.5 , pp. 705-716
    • Tsujii, M.1    Kawano, S.2    Tsuji, S.3    Sawaoka, H.4    Hori, M.5    DuBois, R.N.6


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