Optimal treatment strategy for intracranial germ cell tumors: A single institution analysis - Clinical article

Journal of Neurosurgery: Pediatrics

Volumn 4, Issue 6, 2009, Pages 506-514

  Kanamori, Masayuki ^a   Kumabe, Toshihiro ^a   Saito, Ryuta ^a   Yamashita, Yoji ^a   Sonoda, Yukihiko ^a   Ariga, Hisanori ^a   Takai, Yoshihiro ^a   Tominaga, Teiji ^a  

^a TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Chemotherapy; Germinoma; Intracranial germ cell tumor; Reduced dose radiation therapy; Salvage therapy

Indexed keywords

BLEOMYCIN; CARBOPLATIN; CHORIONIC GONADOTROPIN BETA SUBUNIT; CISPLATIN; ETOPOSIDE; IFOSFAMIDE;

ADOLESCENT; ADULT; ARTICLE; BRAIN RADIATION; BRAIN TUMOR; CANCER CHEMOTHERAPY; CANCER RADIOTHERAPY; CHILD; FEMALE; GERM CELL TUMOR; HISTOLOGY; HUMAN; MAJOR CLINICAL STUDY; MALE; MEDICAL RECORD REVIEW; MULTIPLE CYCLE TREATMENT; NEUROSURGERY; OVERALL SURVIVAL; PRIORITY JOURNAL; PROGNOSIS; PROGRESSION FREE SURVIVAL; RADIATION DOSE; RETROSPECTIVE STUDY; SALVAGE THERAPY; TREATMENT OUTCOME; TUMOR DIAGNOSIS; TUMOR RECURRENCE; ADJUVANT THERAPY; DISEASE FREE SURVIVAL; FOLLOW UP; INFANT; KAPLAN MEIER METHOD; LONGITUDINAL STUDY; MIDDLE AGED; MULTIMODALITY CANCER THERAPY; NEOPLASM; NUCLEAR MAGNETIC RESONANCE IMAGING; PRESCHOOL CHILD;

ADOLESCENT; ADULT; BRAIN NEOPLASMS; CHILD; CHILD, PRESCHOOL; COMBINED MODALITY THERAPY; DISEASE-FREE SURVIVAL; FEMALE; FOLLOW-UP STUDIES; GERMINOMA; HUMANS; INFANT; KAPLAN-MEIERS ESTIMATE; LONGITUDINAL STUDIES; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; NEOPLASMS, GERM CELL AND EMBRYONAL; NEUROSURGICAL PROCEDURES; RADIATION DOSAGE; RADIOTHERAPY, ADJUVANT; RETROSPECTIVE STUDIES; TREATMENT OUTCOME; YOUNG ADULT;

EID: 73349085937     PISSN: 19330707     EISSN: 19330715     Source Type: Journal    
DOI: 10.3171/2009.7.PEDS08288     Document Type: Article

References (39)

1. Aoyama H, Shirato H, Ikeda J, Fujieda K, Miyasaka K, Sawamura Y: Induction chemotherapy followed by low-dose involved-field radiotherapy for intracranial germ cell tumors. J Clin Oncol 20:857-865, 2002
2. Balmaceda C, Heller G, Rosenblum M, Diez B, Villablanca JG, Kellie S, et al: Chemotherapy without irradiation-A novel approach for newly diagnosed CNS germ cell tumors: results of an international cooperative trial. The First International Central Nervous System Germ Cell Tumor Study. J Clin Oncol 14:2908-2915, 1996
3. Bamberg M, Kortmann RD, Calaminus G, Becker G, Meisner C, Harms D, et al: Radiation therapy for intracranial germinoma: results of the German cooperative prospective trials MAKEI 83/86/89. J Clin Oncol 17:2585-2592, 1999
4. Baranzelli MC, Patte C, Bouffet E, Couanet D, Habrand JL, Portas M, et al: Nonmetastatic intracranial germinoma: the experience of the French Society of Pediatric Oncology. Cancer 80:1792-1797, 1997
5. Committee of Brain Tumor Registry of Japan: Report of Brain Tumor Registry of Japan (1969-1996). Neurol Med Chir (Tokyo) 43 Suppl:1-111, 2003
6. Endo T, Kumabe T, Ikeda H, Shirane R, Yoshimoto T: Neurohypophyseal germinoma histologically misidentified as granulomatous hypophysitis. Acta Neurochir (Wien) 144:1233-1237, 2002
7. Haas-Kogan DA, Missett BT, Wara WM, Donaldson SS, Lamborn KR, Prados MD, et al: Radiation therapy for intracranial germ cell tumors. Int J Radiat Oncol Biol Phys 56:511-518, 2003
8. Jabbour SK, Zhang Z, Arnold D, Wharam MD: Risk of second tumor in intracranial germinoma patients treated with radiation therapy: the Johns Hopkins experience. J Neurooncol 91:227-232, 2009
9. Jennings MT, Gelman R, Hochberg F: Intracranial germ-cell tumors: natural history and pathogenesis. J Neurosurg 63: 155-167, 1985
10. Kamoshima Y, Sawamura Y, Ikeda J, Shirato H, Aoyama H: Late recurrence and salvage therapy of CNS germinomas. J Neurooncol 90:205-211, 2008
11. Kanamori M, Kumabe T, Tominaga T: Is histological diagnosis necessary to start treatment for germ cell tumours in the pineal region? J Clin Neurosci 15:978-987, 2008
12. Kawabata Y, Takahashi JA, Arakawa Y, Shirahata M, Hashimoto N: Long term outcomes in patients with intracranial germinomas: a single institution experience of irradiation with or without chemotherapy. J Neurooncol 88:161-167, 2008
13. Kellie SJ, Boyce H, Dunkel IJ, Diez B, Rosenblum M, Brualdi L, et al: Intensive cisplatin and cyclophosphamide-based chemotherapy without radiotherapy for intracranial germinomas: failure of a primary chemotherapy approach. Pediatr Blood Cancer 43:126-133, 2004
14. Kersh CR, Constable WC, Eisert DR, Spaulding CA, Hahn SS, Jenrette JM III, et al: Primary central nervous system germ cell tumors: effect of histologic confirmation on radiotherapy. Cancer 61:2148-2152, 1988
15. Kochi M, Itoyama Y, Shiraishi S, Kitamura I, Marubayashi T, Ushio Y: Successful treatment of intracranial nongerminomatous germ cell tumors by administering neoadjuvant chemotherapy and radiation before excision of residual tumors. J Neurosurg 99:106-114, 2003
16. Kon H, Kumabe T, Jokura H, Shirane R: Recurrent intracranial germinoma outside the initial radiation field with progressive malignant transformation. Acta Neurochir (Wien) 144: 611-616, 2002
17. Kumabe T, Kusaka Y, Jokura H, Ikeda H, Shirane R, Yoshimoto T: [Recurrence of intracranial germinoma initially treated with chemotherapy only.] No Shinkei Geka 30:935-942, 2002 (Jpn)
18. Louis DN, Ohgaki H, Wiestler OD, et al (eds): WHO Classification of Tumours of the Central Nervous System, ed 4. Lyon: IARC Press, 2007
19. Matsutani M: Combined chemotherapy and radiation therapy for CNS germ cell tumors. The Japanese experience. J Neurooncol 54:311-316, 2001
20. Matsutani M: Clinical management of primary central nervous system germ cell tumors. Semin Oncol 31:676-683, 2004
21. Matsutani M, Sano K, Takakura K, Fujimaki T, Nakamura O, Funata N, et al: Primary intracranial germ cell tumors: a clinical analysis of 153 histologically verified cases. J Neurosurg 86:446-455, 1997
22. Nakajima T, Kumabe T, Jokura H, Yoshimoto T: Recurrent germinoma in the optic nerve: report of two cases. Neurosurgery 48:214-218, 2001
23. Nakamura T, Kanamori M, Sonoda Y, Watanabe M, Kumabe T, Tominaga T: [Primary yolk sac tumor in the cerebellar vermis. Case report.] No Shinkei Geka 37:173-177, 2009 (Jpn)
24. Nguyen QN, Chang EL, Allen PK, Maor MH, Ater JL, Mahajan A, et al: Focal and craniospinal irradiation for patients with germinoma and pattern of failure. Cancer 107:2228-2236, 2006
25. Ogawa K, Shikama N, Toita T, Nakamura K, Uno T, Onishi H, et al: Long-term results of radiotherapy for intracranial germinoma: a multi-institutional retrospective review of 126 patients. Int J Radiat Oncol Biol Phys 58:705-713, 2004
26. Ogawa K, Toita T, Nakamura K, Uno T, Onishi H, Itami J, et al: Treatment and prognosis of patients with intracranial nongerminomatous malignant germ cell tumors: a multiinstitutional retrospective analysis of 41 patients. Cancer 98:369-376, 2003
27. Ogino H, Shibamoto Y, Takanaka T, Suzuki K, Ishihara S, Yamada T, et al: CNS germinoma with elevated serum human chorionic gonadotropin level: clinical characteristics and treatment outcome. Int J Radiat Oncol Biol Phys 62:803-808, 2005
28. Oka H, Kawano N, Tanaka T, Utsuki S, Kobayashi I, Maezawa H, et al: Long-term functional outcome of suprasellar germinomas: usefulness and limitations of radiotherapy. J Neurooncol 40:185-190, 1998
29. Sawamura Y, Shirato H, Ikeda J, Tada M, Ishii N, Kato T, et al: Induction chemotherapy followed by reduced-volume radiation therapy for newly diagnosed central nervous system germinoma. J Neurosurg 88:66-72, 1998
30. Shibamoto Y, Takahashi M, Sasai K: Prognosis of intracranial germinoma with syncytiotrophoblastic giant cells treated by radiation therapy. Int J Radiat Oncol Biol Phys 37:505-510, 1997
31. Shikama N, Ogawa K, Tanaka S, Toita T, Nakamura K, Uno T, et al: Lack of benefit of spinal irradiation in the primary treatment of intracranial germinoma. A multiinstitutional retrospective review of 180 patients. Cancer 104:126-134, 2005
32. Shim KW, Kim TG, Suh CO, Cho JH, Yoo CJ, Choi JU, et al: Treatment failure in intracranial primary germinomas. Childs Nerv Syst 23:1155-1161, 2007
33. Shirato H, Nishio M, Sawamura Y, Myojin M, Kitahara T, Nishioka T, et al: Analysis of long-term treatment of intracranial germinoma. Int J Radiat Oncol Biol Phys 37:511-515, 1997
34. Sonoda Y, Kumabe T, Sugiyama S, Kanamori M, Yamashita Y, Saito R, et al: Germ cell tumors in the basal ganglia: problems of early diagnosis and treatment. J Neurosurg Pediatr 2:118-124, 2008
35. Sugiyama S, Kumabe T, Mino M, Fujimura M, Fujiwara I, Tominaga T: [Precocious puberty caused by hCG-producing germinoma involving the bilateral basal ganglia and cerebral white matter without typical radiologic findings: case report.] No Shinkei Geka 34:619-624, 2006 (Jpn)
36. Syndikus I, Tait D, Ashley S, Jannoun L: Long-term follow-up of young children with brain tumors after irradiation. Int J Radiat Oncol Biol Phys 30:781-787, 1994
37. Tian C, Pu C, Wu W, Huang X, Lang S, Yu S, et al: Is biopsy needed to guide management for all patients with presumed intracranial ectopic germinomas? J Neurooncol 92:37-44, 2009
38. Weiner HL, Lichtenbaum RA, Wisoff JH, Snow RB, Souweidane MM, Bruce JN, et al: Delayed surgical resection of central nervous system germ cell tumors. Neurosurgery 50: 727-734, 2002
39. Wolden SL, Wara WM, Larson DA, Prados MD, Edwards MS, Sneed PK: Radiation therapy for primary intracranial germ-cell tumors. Int J Radiat Oncol Biol Phys 32:943-949, 1995