Intensive cisplatin and cyclophosphamide-based chemotherapy without radiotherapy for intracranial germinomas: Failure of a primary chemotherapy approach

Pediatric Blood and Cancer

Volumn 43, Issue 2, 2004, Pages 126-133

  Kellie, Stewart J ^a   Boyce, Hayden ^b   Dunkel, Ira J ^b   Diez, Blanca ^b   Rosenblum, Marc ^b   Brualdi, Lynette ^b   Finlay, Jonathan L ^b  

^a CHILDREN S HOSPITAL AT WESTMEAD   (Australia)

^b NONE

Author keywords

Brain tumor; Chemotherapy; CNS germinomas; Germ cell tumors

Indexed keywords

BLEOMYCIN; CARBOPLATIN; CISPLATIN; CYCLOPHOSPHAMIDE; ETOPOSIDE; IFOSFAMIDE; VANCOMYCIN;

ADOLESCENT; ADULT; ANTINEOPLASTIC ACTIVITY; ARTICLE; BONE MARROW SUPPRESSION; BRAIN HEMORRHAGE; BRAIN TUMOR; CANCER CHEMOTHERAPY; CANCER LOCALIZATION; CANCER RADIOTHERAPY; CANCER SURVIVAL; CHILD; CLINICAL ARTICLE; DIABETES INSIPIDUS; DISEASE ASSOCIATION; DOSE TIME EFFECT RELATION; DRUG DOSE REGIMEN; FEBRILE NEUTROPENIA; FEMALE; GERM CELL TUMOR; GRAND MAL EPILEPSY; HEARING IMPAIRMENT; HEMORRHAGIC CYSTITIS; HUMAN; KIDNEY FAILURE; LEUKOENCEPHALOPATHY; LUNG DISEASE; MALE; MORTALITY; NEUTROPENIA; OLIGURIA; OTOTOXICITY; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; REMISSION; SIDE EFFECT; SURVIVAL TIME; THROMBOCYTOPENIA; THROMBOTIC THROMBOCYTOPENIC PURPURA; TREATMENT OUTCOME;

ADOLESCENT; ADULT; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; AUSTRALIA; BRAIN NEOPLASMS; CHILD; CHILD, PRESCHOOL; CISPLATIN; CYCLOPHOSPHAMIDE; DISEASE-FREE SURVIVAL; FEMALE; GERMINOMA; HUMANS; INFANT; MALE; SURVIVAL RATE;

EID: 3042716684     PISSN: 15455009     EISSN: None     Source Type: Journal    
DOI: 10.1002/pbc.20026     Document Type: Article

References (34)

1. Shibamoto Y, Mitsuyuki A, Yamashita J, et al. Treatment results of intracranial germinoma as a function of irradiated volume. Int J Radiat Oncol Biol Phys 1988;15:285-290.
2. Calaminus G, Bamberg M, Baranzelli MC, et al. Intracranial germ-cell tumors: A comprehensive update of the European data. Neuropediatrics 1994;25:26-32.
3. Hoffman HJ, Otsubo H, Hendrick EB, et al. Intracranial germ-cell tumors in children. J Neurosurg 1991;74:545-551.
4. Dearnaley DP, Ahern BS, Whittaker S, et al. Pineal and CNS germ cell tumours: Royal Marsden Hospital experience 1962-1987. Int J Radiat Oncol Biol Phys 1988;18:773-781.
5. Fields JN, Fulling KH, Thomas PRM, et al. Suprasellar germinoma: Radiation therapy. Radiology 1987;164:247-249.
6. Rich TA, Cassady JR, Strand RD, et al. Radiation therapy for pineal and suprasellar germ cell tumors. Cancer 1985;55:932-940.
7. Balmaceda C, Heller G, Rosenblum M, et al. Chemotherapy without irradiation-a novel approach for newly diagnosed CNS germ cell tumors: Results of an international cooperative trial. J Clin Oncol 1996;14:2908-2915.
8. Dean AG, Dean JA, Coulombier D, et al. Epilnfo, version 6: A word processing, database, and statistics program for epidemiology on microcomputers. Centers for Disease Control and Prevention, Atlanta, Georgia, USA, 1994.
9. Peto R, Peto J. Asymptotically efficient rank invariant test procedures. J R Stat Soc A 1972;135:185-206.
10. Einhorn LH. Clinical trials in testicular cancer. Cancer 1993;71:3182-3184.
11. Nichols CR, Williams SD, Loehrer PJ, et al. Randomized study of cisplatin dose intensity in advanced germ cell tumors: A Southeastern and Southwest Oncology Group protocol. J Clin Oncol 1991;9:1163-1172.
12. Ozols RF, Ihde DC, Linehan WM, et al. A randomized trial of standard chemotherapy vs a high dose chemotherapy regimen in treatment of poor prognosis non-seminomatous germ cell tumors. J Clin Oncol 1988;6:1031-1040.
13. Peckham MJ, Horwich A, Hendry WI. Advanced seminoma treatment with cisplatin-based chemotherapy or carboplatin.
14. Pinkerton CR, Broadbent V, Horwich A, et al. 'JEB'-a carboplatin based regimen for malignant germ cell tumors in children. Br J Cancer 1990;62:257-262.
15. Bajorin DF, Sarasody MF, Pfister DG, et al. Randomized trial of etoposide and cisplatin versus etoposide and carboplatin in patients with good-risk germ cell tumors: A multiinstitutional study. J Clin Oncol 1993;11:598-606.
16. Lindstadt D, Wara WM, Edwards MSB, et al. Radiotherapy of primary intracranial germinomas: The case against routine craniospinal irradiation. Int J Radiat Oncol Biol Phys 1988;15:291-297.
17. Jenkin D, Berry M, Chan H, et al. Pineal region germinomas in childhood. Treatment considerations. Int J Radiat Oncol Biol Phys 1990;18:541-545.
18. Shibamoto Y, Takahashi M, Abe M. Reduction of radiation dose for intracranial germinoma: A prospective study. Br J Cancer 1994;70:984-989.
19. Wolden SL, Wara WM, Larson DA, et al. Radiation therapy for primary intracranial germ-cell tumors. Int J Radiat Oncol Biol Phys 1995;32:943-949.
20. Bamberg M, Kortmann R-D, Calaminus G, et al. Radiation therapy for intracranial germinoma: Results of the German Cooperative Prospective trials MAKEI 83/86/89. J Clin Oncol 1999;17:2585-2592.
21. Hardenbergh PH, Golden J, Billet A, et al. Intracranial germinoma: The case for lower dose radiation therapy. Int J Radiat Oncol Biol Phys 1997;39:419-426.
22. Bouffet E, Baranzelli MC, Patte C, et al. Combined treatment modality for intracranial germinomas: Results of a multicentre SFOP experience. Eur J Cancer 1999;79:1199-1204.
23. Copeland DR, Fletcher JM, Pfefferbaum-Levine B, et al. Neuropsychological sequelae of childhood cancer in long-term survivors. Pediatrics 1985;75:745-753.
24. Constine LS, Woolf PD, Cann D, et al. Hypothalamic-pituitary dysfunction after radiation for brain tumors. N Engl J Med 1993;328:87-94.
25. Duffner PK, Cohen ME, Thomas PR, et al. The long-term effects of cranial irradiation on the central nervous system. Cancer 1985;56:1841-1846.
26. Lannering B, Marky I, Lundberg A, et al. Long-term sequelae after pediatric brain tumors: Their effect on disability and quality of life. Med Pediatr Oncol 1990;18:304-310.
27. Mulhern R, Kepner JL, Thomas PR, et al. Neuropsychologic functioning of survivors of childhood medulloblastoma randomized to receive conventional or reduced-dose craniospinal irradiation: A Pediatric Oncology Group study. J Clin Oncol 1998;16:1723-1728.
28. Radcliffe J, Packer RJ, Atkins TE, et al. Three- and four-year cognitive outcome in children with noncortical brain tumors treated with whole brain radiotherapy. Ann Neurol 1992;32:551-554.
29. Crossen JR, Garwood D, Glatstein E, et al. Neurobehavioural sequelae of cranial irradiation in adults: A review of radiation-induced encephalopathy. J Clin Oncol 1994;12:627-642.
30. Li FP, Cassady JR, Jaffe N. Risk of second tumors in survivors of childhood cancer. Cancer 1975;35:1230-1235.
31. Bosl GJ, Dmitrovsky E, Reuter VE, et al. Isochromosome of chromosome 12: Clinically useful marker for male germ cell tumors. JNCI 1989;81:1874.
32. Oosterhuis JW, Castedo SMMJ, deJong B, et al. Ploidy of subtypes of primary germ cell tumors of the testis. Pathogenetic and clinical relevance. Lab Invest 1989;60:14-21.
33. Oosterhuis JW, Rammeloo RHU, Cornelisse CJ, et al. Ploidy of malignant mediastinal germ cell tumors. Hum Pathol 1990;21:729-732.
34. Sands SA, Kellie SJ, Davidow AL, et al. Long-term quality of life and neuropsychologic functioning for patients with CNS germ-cell tumors: From the First International CNS Germ Cell Tumor Study. Neurol Oncol 2001;3:174-183.