Ultra scale-down approaches for clarification of mammalian cell culture broths in disc-stack centrifuges

Biotechnology Progress

Volumn 25, Issue 6, 2009, Pages 1709-1716

  Zaman, Ferhana ^a   Allan, Corey M ^a   Ho, Sa V ^a  

^a PFIZER INC   (United States)

Author keywords

Centrifuge; Clarification; Filtration; Monoclonal antibody; Scale down

Indexed keywords

CELL LINES; CLARIFICATION PERFORMANCE; FLOWTHROUGH; HIGH SPEED ROTATION; MAMMALIAN CELL CULTURE; NARROW CHANNEL; SCALE DOWN; SHEAR DEVICES; SHEAR EFFECT; SHEAR RESPONSE; THERAPEUTIC MONOCLONAL ANTIBODIES; ULTRA SCALE-DOWN; UNIVERSITY COLLEGE LONDON;

ALLERGIES; ANIMAL CELL CULTURE; CENTRIFUGATION; CENTRIFUGES; CLARIFICATION; CLARIFIERS; MAMMALS; MERGERS AND ACQUISITIONS; MONOCLONAL ANTIBODIES; PARTICLE SIZE ANALYSIS; SURFACE PLASMON RESONANCE;

CELL CULTURE;

MONOCLONAL ANTIBODY;

ANIMAL; ARTICLE; BIOSYNTHESIS; CELL LINE; CENTRIFUGATION; CHO CELL; CRICETULUS; CULTURE TECHNIQUE; FILTRATION; HAMSTER; METHODOLOGY; PARTICLE SIZE; PILOT STUDY; SHEAR STRENGTH;

ANIMALS; ANTIBODIES, MONOCLONAL; CELL CULTURE TECHNIQUES; CELL LINE; CENTRIFUGATION; CHO CELLS; CRICETINAE; CRICETULUS; FILTRATION; PARTICLE SIZE; PILOT PROJECTS; SHEAR STRENGTH;

MAMMALIA;

EID: 73249147912     PISSN: 87567938     EISSN: None     Source Type: Journal    
DOI: 10.1002/btpr.275     Document Type: Article

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