The increased expression of matrix metalloproteinase-9 messenger RNA in the non-lesional skin of patients with large plaque psoriasis vulgaris

Annals of Dermatology

Volumn 21, Issue 1, 2009, Pages 27-34

  Lee, Sang Eun ^a   Lew, Wook ^a  

^a Yonsei University College of Medicine   (South Korea)

Author keywords

Large plaque type; Matrix metalloproteinase 9; Psoriasis vulgaris; Small plaque type

Indexed keywords

EID: 73249146515     PISSN: 10139087     EISSN: None     Source Type: Journal    
DOI: 10.5021/ad.2009.21.1.27     Document Type: Article

References (44)

1. Lowes MA, Bowcock AM, Krueger JG. Pathogenesis and therapy of psoriasis. Nature 2007;445:866-873.
2. Austin LM, Ozawa M, Kikuchi T, Walters IB, Krueger JG. The majority of epidermal T cells in Psoriasis vulgaris lesions can produce type 1 cytokines, interferon-gamma, interleu-kin-2, and tumor necrosis factor-alpha, defining TC1 (cytotoxic T lymphocyte) and TH1 effector populations: a type 1 differentiation bias is also measured in circulating blood T cells in psoriatic patients. J Invest Dermatol 1999; 113:752-759.
3. Jariwala SP. The role of dendritic cells in the immuno-pathogenesis of psoriasis. Arch Dermatol Res 2007;299:359-366.
4. Terui T, Ozawa M, Tagami H. Role of neutrophils in induction of acute inflammation in T-cell-mediated immune dermatosis, psoriasis: a neutrophil-associated inflammation-boosting loop. Exp Dermatol 2000;9:1-10.
5. Nickoloff BJ. Characterization of lymphocyte-dependent angiogenesis using a SCID mouse: human skin model of psoriasis. J Investig Dermatol Symp Proc 2000;5:67-73.
6. Bowcock AM, Shannon W, Du F, Duncan J, Cao K, Aftergut K, et al. Insights into psoriasis and other inflammatory diseases from large-scale gene expression studies. Hum Mol Genet 2001;10:1793-1805.
7. Rottman J.B., Smith T.L., Ganley K.G., Kikuchi T., Krueger J.G. Potential role of the chemokine receptors CXCR3, CCR4, and the integrin alphaEbeta7 in the pathogenesis of psoriasis vulgaris. Lab Invest 2001;81:335-347.
8. Lew W, Bowcock AM, Krueger JG. Psoriasis vulgaris: cutaneous lymphoid tissue supports T-cell activation and "Type 1" inflammatory gene expression. Trends Immunol 2004;25:295-305.
9. Lew W, Lee E, Krueger JG. Psoriasis genomics: analysis of proinflammatory (type 1) gene expression in large plaque (Western) and small plaque (Asian) psoriasis vulgaris. Br J Dermatol 2004;150:668-676.
10. Dinarello CA. lnterleukin-1 beta, interleukin-18, and the interleukin-1 beta converting enzyme. Ann N Y Acad Sci 1998;856:1-11.
11. Abraham M, Shapiro S, Lahat N, Miller A. The role of IL-18 and IL-12 in the modulation of matrix metalloproteinases and their tissue inhibitors in monocytic cells. Int Immunol 2002;14:1449-1457.
12. Zhang B, Wu KF, Cao ZY, Rao Q, Ma XT, Zheng GG, et al. IL-18 increases invasiveness of HL-60 myeloid leukemia cells: up-regulation of matrix metalloproteinases-9 (MMP-9) expression. Leuk Res 2004;28:91-95.
13. Tamai K, Ishikawa H, Mauviel A, Uitto J. Interferon-gamma coordinately upregulates matrix metalloprotease (MMP)-1 and MMP-3, but not tissue inhibitor of metalloproteases (TIMP), expression in cultured keratinocytes. J Invest Dermatol 1995;104:384-390.
14. Hebenstreit D, Wirnsberger G, Horejs-Hoeck J, Duschl A. Signaling mechanisms, interaction partners, and target genes of STAT6. Cytokine Growth Factor Rev 2006;17:173-188.
15. Kruse N, Pette M, Toyka K, Rieckmann P. Quantification of cytokine mRNA expression by RT. PCR in samples of previously frozen blood. J Immunol Methods 1997;210: 195-203.
16. Heid CA, Stevens J, 'iivak KJ, Williams PM. Real time quantitative PCR. Genome Res 1996;6:986-994.
17. van Ruissen F, Le ́ Carroll JM, van der Valk PG, Schalkwijk J. Differential effects of detergents on keratinocyte gene expression. J Invest Dermatol 1998;110:358-363.
18. Mauviel A. Cytokine regulation of metalloproteinase gene expression. J Cell Biochem 1993;53:288-295.
19. Saren P, Welgus HG, Kovanen PT. TNF-alpha and IL-lbeta selectively induce expression of 92-kDa gelatinase by human macrophages. J Immunol 1996;157:4159-4165.
20. Lavigne MC, Thakker P, Gunn J, Wong A, Miyashiro JS, Wasserman AM, et al. Human bronchial epithelial cells express and secrete MMP-12. Biochem Biophys Res Com- mun 2004;324:534-546.
21. Wolk K, Witte E, Wallace E, Docke WD, Kunz S, Asadullah K, et al. IL-22 regulates the expression of genes responsible for antimicrobial defense, cellular differentiation, and mobility in keratinocytes: a potential role in psoriasis. Eur J Immunol 2006;36:1309-1323.
22. Opdenakker G, Van den Steen PE, Van Damme J. Gelatinase B: a tuner and amplifier of immune functions. Trends Immunol 2001;22:571-579.
23. Fleischmajer R, Kuroda K, Hazan R, Gordon RE, Lebwohl MG, Sapadin AN, et al. Basement membrane alterations in psoriasis are accompanied by epidermal overexpression of MMP-2 and its inhibitor TIMP-2. J Invest Dermatol 2000; 115:771-777.
24. Suomela S, Kariniemi AL, Snellman E, Saarialho-Kere U. Metalloelastase (MMP-12) and 92-kDa gelatinase (MMP-9) as well as their inhibitors, TIMP-1 and -3, are expressed in psoriatic lesions. Exp Dermatol 2001;10:175-183.
25. Thewes M, Worret Wl, Engst R, Ring J. Stromelysin-3 (ST-3): Immunohistochemical characterization of the matrix me talloproteinase (MMP)-11 in benign and malignant skin tumours and other skin disorders. Clin Exp Dermatol 1999;24:122-126.
26. Suomela S, Kariniemi AL, Impola U, Karvonen SL, Snellman E, Uurasmaa T, et al. Matrix metalloproteinase-19 is expressed by keratinocytes in psoriasis. Acta Derm Venereol 2003;83:108-114.
27. Nestle FO, Conrad C, Tun-Kyi A, Homey B, Gombert M, Boyman O, et al. Plasmacytoid predendritic cells initiate psoriasis through interferon-alpha production. J Exp Med 2005;202:135-143.
28. Nestle FO, Gilliet M. Defining upstream elements of psoriasis pathogenesis: an emerging role for interferon alpha. J Invest Dermatol 2005;125:14-15.
29. Ninomiya T, Yoon S, Nagano H, Kumon Y, Seo Y, Kasuga M, et al. Significance of serum matrix metalloproteinases and their inhibitors on the antifibrogenetic effect of inter- feron-alfa in chronic hepatitis C patients. Intervirology 2001;44:227-231.
30. Flisiak I, Porebski P, Chodynicka B. Effect of psoriasis activity on metalloproteinase-1 and tissue inhibitor of metallopro-teinase-1 in plasma and lesional scales. Acta Derm Venereol 2006;86:17-21.
31. Flisiak I, Mysliwiec H, Chodynicka B. Effect of psoriasis treatment on plasma concentrations of metalloproteinase-1 and tissue inhibitor of metalloproteinases-1. J Eur Acad Dermatol Venereol 2005;19:418-421. (Pubitemid 40946092)
32. Feliciani C, Vitullo P, D'Orazi G, Palmirotta R, Amerio P, Pour SM, et al. The 72-kDa and the 92-kDa gelatinases, but not their inhibitors TIMP-1 and TIMP-2, are expressed in early psoriatic lesions. Exp Dermatol 1997;6:321-327.
33. Nickoloff BJ, Karabin GD, Barker JN, Griffiths CE, Sarma V, Mitra RS, et al. Cellular localization of interleukin-8 and its inducer, tumor necrosis factor-alpha in psoriasis. Am J Pathol 1991;138:129-140.
34. Ettehadi P, Greaves MW, Wallach D, Aderka D, Camp RD. Elevated tumour necrosis factor-alpha (TNF-alpha) biological activity in psoriatic skin lesions. Clin Exp Immunol 1994;96:146-151.
35. Uyemura K, Yamamura M, Fivenson DF, Modlin RL, Nickoloff BJ. The cytokine network in lesional and lesion-free psoriatic skin is characterized by a T-helper type 1 cell-mediated response. J Invest Dermatol 1993;101:701-705.
36. Schlaak JF, Buslau M, Jochum W, Hermann E, Girndt M, Gallati H, et al. T cells involved in psoriasis vulgaris belong totheThl subset. J Invest Dermatol 1994;102:145-149.
37. Nickoloff BJ. Role of interferon-gamma in cutaneous trafficking of lymphocytes with emphasis on molecular and cellular adhesion events. Arch Dermatol 1988;124:1835-1843.
38. Szabo SK, Hammerberg C, Yoshida Y, Bata-Csorgo Z, Cooper KD. Identification and quantitation of interferon-gamma producing T cells in psoriatic lesions: Localization to both CD4+ and CD8+ subsets. J Invest Dermatol 1998;111:1072-1078.
39. Giannelli G, Brassard J, Foti C, Stetler-Stevenson WG, Falk-Marzillier J, Zambonin-Zallone A, et al. Altered expression of basement membrane proteins and their integrin receptors in lichen planus: possible pathogenetic role of gelatinases A and B. Lab Invest 1996;74:1091-1104.
40. Niimi Y, Pawankar R, Kawana S. Increased expression of matrix metalloproteinase-2, matrix metalloproteinase-9 and matrix metalloproteinase-13 in lesional skin of bullous pemphigoid. Int Arch Allergy Immunol 2006;139:104-113.
41. ordiali-Fei P, Trento E, D'Agosto G, Bordignon V, Mussi A, Ardigo M, et al. Decreased levels of metalloproteinase-9 and angiogenic factors in skin lesions of patients with psoriatic arthritis after therapy with anti-TNF-alpha. J Autoimmune Dis 2006;3:5.
42. Cordiali-Fei P, Trento E, D'Agosto G, Bordignon V, Mussi A, Ardigo M, et al. Effective therapy with anti-TNF-alpha in patients with psoriatic arthritis is associated with decreased levels of metalloproteinases and angiogenic cytokines in the sera and skin lesions. Ann N Y Acad Sci 2007;1110:578-589.
43. Papathoma AS, Zoumpourlis V, Balmain A, Pintzas A. Role of matrix metalloproteinase-9 in progression of mouse skin carcinogenesis. Mol Carcinog 2001;31:74-82.
44. Itoh T, Tanioka M, Matsuda H, Nishimoto H, Yoshioka T, Suzuki R, et al. Experimental metastasis is suppressed in MMP-9-deficient mice. Clin Exp Metastasis 1999;17:177-181.