The long-term release of antibiotics from monolithic nonporous polymer implants for use as tympanostomy tubes

Colloids and Surfaces A: Physicochemical and Engineering Aspects

Volumn 354, Issue 1-3, 2010, Pages 331-337

  Labib, Mohamed E ^a   Brumlik, Charles J ^a   Stoodley, Paul ^b   Dukhin, Stanislav S ^a   Davidson, Theodore ^a   Tabani, Yacoob ^a  

^a Novaflux Technologies   (United States)

^b UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

Author keywords

Drug dissolution rate; Drug particle aggregation; Drug particle size; Drug release; Extrusion; Monolithic nonporous polymer implants; Otitis media; Tympanostomy tube

Indexed keywords

ANTIBIOTICS; BIOLOGICAL MEMBRANES; BLENDING; DIFFUSION; DISSOLUTION; EXTRUSION; PARTICLE SIZE; POLYMER MELTS; TUBES (COMPONENTS);

DRUG DISSOLUTION; DRUG PARTICLE AGGREGATION; DRUG RELEASE; OTITIS MEDIA; PARTICLE AGGREGATION; POLYMER IMPLANTS;

AGGLOMERATION;

ANTIBIOTIC AGENT; CIPROFLOXACIN; ETHYLENE VINYL ACETATE COPOLYMER; POLY(HEXAMETHYLENEBIGUANIDE); POLYMER; POLYURETHAN; USNIC ACID;

ARTICLE; BACTERIAL GROWTH; BIOFILM; CONTROLLED DRUG RELEASE; CONTROLLED STUDY; DIFFUSION; DRUG ACCUMULATION; DRUG SOLUBILITY; HAEMOPHILUS INFLUENZAE; IN VITRO STUDY; MIDDLE EAR IMPLANT; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; OTITIS MEDIA; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA; RECURRENT INFECTION; STAPHYLOCOCCUS AUREUS; STEADY STATE; STREPTOCOCCUS PNEUMONIAE; TRANSPORT KINETICS; TYMPANOSTOMY TUBE;

EID: 73249132185     PISSN: 09277757     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.colsurfa.2009.10.028     Document Type: Article

References (27)

1. Frontiers in Formulation Science, Selected Papers from 5th International Conference on Formulation Technology, November 2007, Potsdam, Germany, Colloids. Surf. A 331, 2008.
2. Park K., and Stowell J.G. Controlled Drug-Delivery Systems (2004), Stipes Publishing, LLC Champaign, IL
3. Crank J. The Mathematics of Diffusion. 2nd ed. (1979), Clarendon Press, Oxford
4. Higuchi T. J. Soc. Cosmet. Chem. 11 (1960) 85-97
5. Higuchi T. J. Pharm. Sci. 50 (1961) 874-875
6. Paul D.R., and McSpadden S.K. J. Membr. Sci. 1 (1976) 33-48
7. Lee P.I. J. Membr. Sci. 7 (1980) 255-275
8. Bunge A.L. J. Control. Rel. 52 (1998) 141-148
9. Bunge A.L., and Miller R.L. Chemical Engineering Education Fall (1997) 254-259
10. Chamarthy S.P., and Pinal R. Colloids Surf. A 331 (2008) 25-30
11. Levich V.G. Physico-chemical Hydrodynamics (1962), Prentice Hall, Englewood Cliffs, NJ
12. Lyklema J. Fundamentals of Interface and Colloid Science vol. 1 (1991), Academic Press, London, New York (Chapter 6)
13. Roseman T.J., and Higuchi W. J. Pharm. Sci. 59 (1970) 353-357
14. Tojo K. J. Pharm. Sci. 74 (1985) 685-687
15. Zhou Y., and Wu X.Y. J. Control. Rel. 84 (2002) 1-13
16. Abdekhodaie M.J., and Cheng Y.-L. J. Control. Rel. 43 (1997) 175-182
17. Zheng F. J. Control. Rel. 55 (1998) 99
18. Hall-Stoodley L., Hu F.Z., Gieseke A., Nistico L., Nguyen D., Hayes J., Forbes M., Greenberg D.P., Dice B., Burrows A., Wackym P.A., Stoodley P., Post J.C., Ehrlich G.D., and Kerschner J.E. JAMA 296 2 (2006) 202-211
19. Lelah M.D., and Cooper S.L. Polyurethanes in Medicine (1986), CRC Press (Chapters 4 and 5)
20. Website: http://www.dow.com/footwear/products/pellethane.htm.
21. Uhrich K.E., Cannizzaro S.M., Langer R.S., and Shakesheff K.M. Chem. Rev. 99 (1999) 3181-3198
22. Ross D.L., and Riley C.M. Int. J. Pharm. 63 (1990) 237-250
23. Hidalgo M.E., Bascunan L., Quilhot W., Fernandez E., and Rubio C. Photochem. Photobiol. 81 6 (2005) 1447-1449
24. Francolini I., Norris P., Piozzi A., Donelli G., and Stoodley P. Antimicrob. Agents Chemother. 48 11 (2004) 4360-4365
25. Ayres J.W., and Lindstrom F.T. J. Pharm. Sci. 66 (1977) 654-662
26. Lindstrom F.T., and Ayres J.W. J. Pharm. Sci. 66 (1977) 662-668
27. Frenning G. J. Control. Rel. 92 (2003) 331-339