POP levels in breast milk and maternal serum and thyroid hormone levels in mother-child pairs from Uppsala, Sweden

Environment International

Volumn 36, Issue 2, 2010, Pages 180-187

  Darnerud, P O ^a   Lignell, S ^a   Glynn, A ^a   Aune, M ^a   Tornkvist A ^a   Stridsberg, Mats ^b  

^a NATIONAL FOOD ADMINISTRATION   (Sweden)

^b UPPSALA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

DDE; Dioxins; PCB; T3; T4; Thyroid hormone; TSH

Indexed keywords

BLOOD; BODY FLUIDS; HORMONES; POLLUTION; POLYCHLORINATED BIPHENYLS; REGRESSION ANALYSIS;

DIOXINS; EPIDEMIOLOGICAL STUDIES; PERSISTENT ORGANIC POLLUTANTS; PERSONAL CHARACTERISTICS; REFERENCE RANGE; SIMPLE REGRESSION ANALYSIS; THYROID HORMONES; THYROID STIMULATING HORMONES;

ORGANIC POLLUTANTS;

1,1 DICHLORO 2,2 BIS(4 CHLOROPHENYL)ETHYLENE; CB 153; LIOTHYRONINE; ORGANOCHLORINE DERIVATIVE; POLYCHLORINATED BIPHENYL; POLYCHLORINATED DIBENZODIOXIN; THYROID HORMONE; THYROTROPIN; THYROXINE; UNCLASSIFIED DRUG;

BLOOD; BREASTFEEDING; CHILD HEALTH; DDE; DIOXIN; EXPERIMENTAL STUDY; HEALTH IMPACT; HORMONE; MILK; ORGANIC POLLUTANT; PCB; POLLUTION EFFECT; POLLUTION EXPOSURE; POLLUTION MONITORING; REGRESSION ANALYSIS;

ADULT; ARTICLE; BLOOD LEVEL; BLOOD SAMPLING; CHEMICAL ANALYSIS; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; ENVIRONMENTAL EXPOSURE; FEMALE; FREE THYROXINE INDEX; HORMONE DETERMINATION; HUMAN; INFANT; MALE; MATERNAL BLOOD; MILK LEVEL; PRIMIPARA; PRIORITY JOURNAL; SWEDEN; TOXICITY TESTING;

SWEDEN; UPPSALA [SWEDEN];

EID: 73249131220     PISSN: 01604120     EISSN: 18736750     Source Type: Journal    
DOI: 10.1016/j.envint.2009.11.001     Document Type: Article

References (65)

1. Asawasinsopon R., Prapamontol T., Prakobvitayakit O., Vaneesorn Y., Mangklabruks A., and Hock B. The association between organochlorine and thyroid hormone levels in cord serum: a study from northern Thailand. Environ Int 32 4 (2006) 554-559
2. Atuma S.S., and Aune M. Method for the determination of PCB congeners and chlorinated pesticides in human blood serum. Bull Environ Contam Toxicol 62 1 (1999) 8-15
3. Aune M., Atuma S., Darnerud P.O., Wicklund-Glynn A., and Cnattingius S. Analysis of organochlorine compounds in human milk. Organohalog Compd 40 (1999) 87-90
4. Belin R.M., Astor B.C., Powe N.R., and Ladenson P.W. Smoke exposure is associated with a lower prevalence of serum thyroid autoantibodies and thyrotropin concentration elevation and a higher prevalence of mild thyrotropin concentration suppression in the third National Health and Nutrition Examination Survey (NHANES III). J Clin Endocrinol Metab 89 12 (2004) 6077-6086
5. Bignert A., Olsson M., Persson W., Jensen S., Zakrisson S., Litzen K., et al. Temporal trends of organochlorines in Northern Europe, 1967-1995. Relation to global fractionation, leakage from sediments and international measures. Environ Pollut 99 2 (1998) 177-198
6. Bjerselius R., Darnerud P.O., Aune M., Atuma S., Lind Y., and Glynn A. Significant changes of serum concentrations of lipid and PCB during pregnancy and nursing. Organohalog Compd 52 (2001) 189-191
7. Branchi I., Capone F., Vitalone A., Madia F., Santucci D., Alleva E., et al. Early developmental exposure to BDE 99 or Aroclor 1254 affects neurobehavioural profile: interference from the administration route. Neurotoxicology 26 2 (2005) 183-192
8. Brouwer A., Blaner W.S., Kukler A., and Van den Berg K.J. Study on the mechanism of interference of 3, 4, 3′, 4′-tetrachlorobiphenyl with the plasma retinol-binding proteins in rodents. Chem Biol Interact 68 3-4 (1988) 203-217
9. Brouwer A., Morse D.C., Lans M.C., Schuur A.G., Murk A.J., Klasson-Wehler E., et al. Interactions of persistent environmental organohalogens with the thyroid hormone system: mechanisms and possible consequences for animal and human health. Toxicol Ind Health 14 1-2 (1998) 59-84
10. Calvert G.M., Sweeney M.H., Deddens J., and Wall D.K. Evaluation of diabetes mellitus, serum glucose, and thyroid function among United States workers exposed to 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin. Occup Environ Med 56 4 (1999) 270-276
11. Chevrier J., Eskenazi B., Bradman A., Fenster L., and Barr D.B. Associations between prenatal exposure to polychlorinated biphenyls and neonatal thyroid-stimulating hormone levels in a Mexican-American population, Salinas Valley, California. Environ Health Perspect 115 10 (2007) 1490-1496
12. Clausson B., Granath F., Ekbom A., Lundgren S., Nordmark A., Signorello L.B., et al. Effect of caffeine exposure during pregnancy on birth weight and gestational age. Am J Epidemiol 155 5 (2002) 429-436
13. Consonni D., Pesatori A.C., Zocchetti C., Sindaco R., D'Oro L.C., Rubagotti M., et al. Mortality in a population exposed to dioxin after the Seveso, Italy, accident in 1976: 25 years of follow-up. Am J Epidemiol 167 7 (2008) 847-858
14. Covaci A., Jorens P., Jacquemyn Y., and Schepens P. Distribution of PCBs and organochlorine pesticides in umbilical cord and maternal serum. Sci Total Environ 298 1-3 (2002) 45-53
15. Dallaire R., Dewailly E., Ayotte P., Muckle G., Laliberte C., and Bruneau S. Effects of prenatal exposure to organochlorines on thyroid hormone status in newborns from two remote coastal regions in Quebec, Canada. Environ Res 108 3 (2008) 387-392
16. Dorea J.G. Iodine nutrition and breast feeding. J Trace Elem Med Biol 16 4 (2002) 207-220
17. Dussault J.H., and Ruel J. Thyroid hormones and brain development. Annu Rev Physiol 49 (1987) 321-334
18. Eriksson P., Fischer C., and Fredriksson A. Polybrominated diphenyl ethers, a group of brominated flame retardants, can interact with polychlorinated biphenyls in enhancing developmental neurobehavioral defects. Toxicol Sci 94 2 (2006) 302-309
19. Ganong W.F. Review of medical physiology (2005), Appleton and Lange, USA 928 pp.
20. Glynn A.W., Atuma S., Aune M., Darnerud P.O., and Cnattingius S. Polychlorinated biphenyl congeners as markers of toxic equivalents of polychlorinated biphenyls, dibenzo-p-dioxins and dibenzofurans in breast milk. Environ Res 86 3 (2001) 217-228
21. Glynn A., Aune M., Darnerud P.O., Cnattingius S., Bjerselius R., Becker W., et al. Determinants of serum concentrations of organochlorine compounds in Swedish pregnant women: a cross-sectional study. Environ Health 6 (2007) 2
22. Grandjean P., Bellinger D., Bergman A., Cordier S., Davey-Smith G., Eskenazi B., et al. The faroes statement: human health effects of developmental exposure to chemicals in our environment. Basic Clin Pharmacol Toxicol 102 2 (2008) 73-75
23. Hagmar L. Polychlorinated biphenyls and thyroid status in humans: a review. Thyroid 13 11 (2003) 1021-1028
24. Hallgren S., Sinjari T., Hakansson H., and Darnerud P.O. Effects of polybrominated diphenyl ethers (PBDEs) and polychlorinated biphenyls (PCBs) on thyroid hormone and vitamin A levels in rats and mice. Arch Toxicol 75 4 (2001) 200-208
25. Herbstman J.B., Sjodin A., Apelberg B.J., Witter F.R., Halden R.U., Patterson D.G., et al. Birth delivery mode modifies the associations between prenatal polychlorinated biphenyl (PCB) and polybrominated diphenyl ether (PBDE) and neonatal thyroid hormone levels. Environ Health Perspect 116 10 (2008) 1376-1382
26. Hryhorczuk D.O., Wallace W.H., Persky V., Furner S., Webster Jr. J.R., Oleske D., et al. A morbidity study of former pentachlorophenol-production workers. Environ Health Perspect 106 7 (1998) 401-408
27. Johansson N., Hanberg A., Wingfors H., and Tysklind M. PCB in building sealant is influencing PCB levels in blood of residents. Organohalog Compd 63 (2003) 381-384
28. Johnson E., Shorter C., Bestervelt L., Patterson D., Needham L., Piper W., et al. Serum hormone levels in humans with low serum concentrations of 2, 3, 7, 8-TCDD. Toxicol Ind Health 17 4 (2001) 105-112
29. Jones M.K., Weisenburger W.P., Sipes I.G., and Russell D.H. Circadian alterations in prolactin, corticosterone, and thyroid hormone levels and down-regulation of prolactin receptor activity by 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin. Toxicol Appl Pharmacol 87 2 (1987) 337-350
30. Kabuto M., Sone H., Imai H., Kurokawa Y., and Yonemoto J. Dioxins in milk or blood in relation to thyroid hormones and other possible biomarkers among people in a highly polluted area in Japan. Organohalog Compd 48 (2000) 9-12
31. Koopman-Esseboom C., Morse D.C., Weisglas-Kuperus N., Lutkeschipholt I.J., Van der Paauw C.G., Tuinstra L.G., et al. Effects of dioxins and polychlorinated biphenyls on thyroid hormone status of pregnant women and their infants. Pediatr Res 36 4 (1994) 468-473
32. LaKind J.S., Berlin C.M., Park C.N., Naiman D.Q., and Gudka N.J. Methodology for characterizing distributions of incremental body burdens of 2, 3, 7, 8-TCDD and DDE from breast milk in North American nursing infants. J Toxicol Environ Health A 59 8 (2000) 605-639
33. Langer P., Kocan A., Tajtakova M., Koska J., Radikova Z., Ksinantova L., et al. Increased thyroid volume, prevalence of thyroid antibodies and impaired fasting glucose in young adults from organochlorine cocktail polluted area: outcome of transgenerational transmission?. Chemosphere 73 7 (2008) 1145-1150
34. Lanting C.I., Fidler V., Huisman M., and Boersma E.R. Determinants of polychlorinated biphenyl levels in plasma from 42-month-old children. Arch Environ Contam Toxicol 35 1 (1998) 135-139
35. Lundqvist C., Zuurbier M., Leijs M., Johansson C., Ceccatelli S., Saunders M., et al. The effects of PCBs and dioxins on child health. Acta Paediatr Suppl 95 453 (2006) 55-64
36. MacLusky N.J., Brown T.J., Schantz S., Seo B.W., and Peterson R.E. Hormonal interactions in the effects of halogenated aromatic hydrocarbons on the developing brain. Toxicol Ind Health 14 1-2 (1998) 185-208
37. Maervoet J., Vermeir G., Covaci A., Van Larebeke N., Koppen G., Schoeters G., et al. Association of thyroid hormone concentrations with levels of organochlorine compounds in cord blood of neonates. Environ Health Perspect 115 12 (2007) 1780-1786
38. Makepeace A.E., Bremner A.P., O'Leary P., Leedman P.J., Feddema P., Michelangeli V., et al. Significant inverse relationship between serum free T4 concentration and body mass index in euthyroid subjects: differences between smokers and nonsmokers. Clin Endocrinol (Oxf) 69 4 (2008) 648-652
39. Matsuura N., Uchiyama T., Tada H., Nakamura Y., Kondo N., Morita M., et al. Effects of dioxins and polychlorinated biphenyls (PCBs) on thyroid function in infants born in Japan-the second report from research on environmental health. Chemosphere 45 8 (2001) 1167-1171
40. Meijer L., Weiss J., Van Velzen M., Brouwer A., Bergman A., and Sauer P.J. Serum concentrations of neutral and phenolic organohalogens in pregnant women and some of their infants in The Netherlands. Environ Sci Technol 42 9 (2008) 3428-3433
41. Nagayama J., Okamura K., Nakagawa R., Iida T., Tsuju H., Hasegawa M., et al. Perinatal exposure to organochlorine pesticides on thyroid hormone status in Japanese breast-fed infants. Organohalog Compd 37 (1998) 235-239
42. Nagayama J., Okamura K., Iida T., Hirakawa H., Matsueda T., Tsuji H., et al. Postnatal exposure to chlorinated dioxins and related chemicals on thyroid hormone status in Japanese breast-fed infants. Chemosphere 37 9-12 (1998) 1789-1793
43. Nagayama J., Iida T., Nakagawa R., Matsueda T., Hirakawa H., Astuti E., et al. Condition of thyroid hormone system in 10-month-old Japanese infants perinatally exposed to organochlorine pesticides, PCBs and dioxins. Organohalog Compd 48 (2000) 236-239
44. Nakamura T., Nakai K., Matsumura T., Suzuki S., Saito Y., and Satoh H. Determination of dioxins and polychlorinated biphenyls in breast milk, maternal blood and cord blood from residents of Tohoku, Japan. Sci Total Environ 394 1 (2008) 39-51
45. Otake T., Yoshinaga J., Enomoto T., Matsuda M., Wakimoto T., Ikegami M., et al. Thyroid hormone status of newborns in relation to in utero exposure to PCBs and hydroxylated PCB metabolites. Environ Res 105 2 (2007) 240-246
46. Ott M.G., Zober A., and Germann C. Laboratory results for selected target organs in 138 individuals occupationally exposed to TCDD. Chemosphere 29 9-11 (1994) 2423-2437
47. Pluim H.J., de Vijlder J.J., Olie K., Kok J.H., Vulsma T., van Tijn D.A., et al. Effects of pre- and postnatal exposure to chlorinated dioxins and furans on human neonatal thyroid hormone concentrations. Environ Health Perspect 101 6 (1993) 504-508
48. Pohjanvirta R., Kulju T., Morselt A.F., Tuominen R., Juvonen R., Rozman K., et al. Target tissue morphology and serum biochemistry following 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin (TCDD) exposure in a TCDD-susceptible and a TCDD-resistant rat strain. Fundam Appl Toxicol 12 4 (1989) 698-712
49. Potter C.L., Sipes I.G., and Russell D.H. Hypothyroxinemia and hypothermia in rats in response to 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin administration. Toxicol Appl Pharmacol 69 1 (1983) 89-95
50. Reed H.L. Circannual changes in thyroid hormone physiology: the role of cold environmental temperatures. Arctic Med Res 54 Suppl 2 (1995) 9-15
51. Sandau C.D., Ayotte P., Dewailly E., Duffe J., and Norstrom R.J. Pentachlorophenol and hydroxylated polychlorinated biphenyl metabolites in umbilical cord plasma of neonates from coastal populations in Quebec. Environ Health Perspect 110 4 (2002) 411-417
52. Schantz S.L., Widholm J.J., and Rice D.C. Effects of PCB exposure on neuropsychological function in children. Environ Health Perspect 111 3 (2003) 357-576
53. Surks M.I., and Hollowell J.G. Age-specific distribution of serum thyrotropin and antithyroid antibodies in the US population: implications for the prevalence of subclinical hypothyroidism. J Clin Endocrinol Metab 92 12 (2007) 4575-4582
54. Takser L., Mergler D., Baldwin M., de Grosbois S., Smargiassi A., and Lafond J. Thyroid hormones in pregnancy in relation to environmental exposure to organochlorine compounds and mercury. Environ Health Perspect 113 8 (2005) 1039-1045
55. Thuresson K., Hoglund P., Hagmar L., Sjodin A., Bergman A., and Jakobsson K. Apparent half-lives of hepta- to decabrominated diphenyl ethers in human serum as determined in occupationally exposed workers. Environ Health Perspect 114 2 (2006) 176-181
56. Triebig G., Werle E., Papke O., Heim G., Broding C., and Ludwig H. Effects of dioxins and furans on liver enzymes, lipid parameters, and thyroid hormones in former thermal metal recycling workers. Environ Health Perspect 106 Suppl 2 (1998) 697-700
57. Van Birgelen A.P., Van der Kolk J., Fase K.M., Bol I., Poiger H., Brouwer A., et al. Subchronic dose-response study of 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin in female Sprague-Dawley rats. Toxicol Appl Pharmacol 132 1 (1995) 1-13
58. Van den Berg M., Birnbaum L., Bosveld A.T., Brunstrom B., Cook P., Feeley M., et al. Toxic equivalency factors (TEFs) for PCBs, PCDDs, PCDFs for humans and wildlife. Environ Health Perspect 106 12 (1998) 775-792
59. Van den Berg M., Birnbaum L.S., Denison M., De Vito M., Farland W., Feeley M., et al. The 2005 World Health Organization reevaluation of human and Mammalian toxic equivalency factors for dioxins and dioxin-like compounds. Toxicol Sci 93 2 (2006) 223-241
60. van der Velde E.G., Marsman J.A., de Jong A.P.J.M., Hoogerbrugge R., and Liem A.K.D. Analysis and occurrence of toxic planar PCBs, PCDDs and PCDFs in milk by use of carbosphere activated carbon. Chemosphere 28 (1994) 693-702
61. Viberg H., Fredriksson A., and Eriksson P. Neonatal exposure to polybrominated diphenyl ether (PBDE 153) disrupts spontaneous behaviour, impairs learning and memory, and decreases hippocampal cholinergic receptors in adult mice. Toxicol Appl Pharmacol 192 2 (2003) 95-106
62. Vreugdenhil H.J., Lanting C.I., Mulder P.G., Boersma E.R., and Weisglas-Kuperus N. Effects of prenatal PCB and dioxin background exposure on cognitive and motor abilities in Dutch children at school age. J Pediatr 140 1 (2002) 48-56
63. Wang S.L., Su P.H., Jong S.B., Guo Y.L., Chou W.L., and Papke O. In utero exposure to dioxins and polychlorinated biphenyls and its relations to thyroid function and growth hormone in newborns. Environ Health Perspect 113 11 (2005) 1645-1650
64. Wilhelm M., Wittsiepe J., Lemm F., Ranft U., Kramer U., Furst P., et al. The Duisburg birth cohort study: influence of the prenatal exposure to PCDD/Fs and dioxin-like PCBs on thyroid hormone status in newborns and neurodevelopment of infants until the age of 24 months. Mutat Res 659 1-2 (2008) 83-92
65. Zhou T., Ross D.G., DeVito M.J., and Crofton K.M. Effects of short-term in vivo exposure to polybrominated diphenyl ethers on thyroid hormones and hepatic enzyme activities in weanling rats. Toxicol Sci 61 1 (2001) 76-82