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Volumn 51, Issue 6, 2010, Pages 970-973

Preparation of 2,4,5-trisubstituted pyrazolo[4,3-c]quinolin-3-ones

Author keywords

Pyrazolo 4,3 c quinolinone; Pyrazolone; Quinolinone

Indexed keywords

PYRAZOLE DERIVATIVE; QUINOLINE DERIVATIVE;

EID: 73249117087     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2009.12.054     Document Type: Article
Times cited : (9)

References (14)
  • 8
    • 73249131714 scopus 로고    scopus 로고
    • note
    • A screening of solvents (tetrahydrofuran, N,N-dimethylformamide, acetonitrile) and bases (potassium carbonate, sodium hydride, cesium carbonate, sodium hydroxide) did not lead to a significant alteration of N5- versus N1-alkylation products. In addition, we have observed in a limited number of cases the formation of O-alkylated materials{A figure is presented}.
  • 12
    • 73249128741 scopus 로고    scopus 로고
    • note
    • During the course of these studies, it was observed that prolonged reaction times at elevated temperatures led to gradual decomposition of the reaction mixture. Shorter reaction times at higher temperatures provided cleaner reaction mixtures and provided compounds in equal to or greater isolated yield.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.