Optimal antagonism of GPIIb/IIIa favors platelet adhesion by inhibiting thrombus growth: An ex vivo capillary perfusion chamber study in the guinea pig

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 16, Issue 1, 1996, Pages 56-63

  André, Patrick ^a,b   Arbeille, Brigitte ^a,c   Drouet, Valérie ^a   Hainaud, Patricia ^a   Sollier, Claire Bal Dit ^a   Caen, Jacques P ^a   Drouet, Ludovic O ^a,b,d  

^a Institut des Vaisseaux et du Sang   (France)

^b INSERM   (France)

^c UNIVERSITÉ DE TOURS   (France)

^d HÔPITAL LARIBOISIÈRE   (France)

Author keywords

adhesion; capillary; GPIIb IIIa antagonist; guinea pig; thrombus

Indexed keywords

COLLAGEN; FIBRINOGEN RECEPTOR ANTAGONIST; LAMIFIBAN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COMPUTER ASSISTED DIAGNOSIS; CONTROLLED STUDY; GUINEA PIG; MORPHOMETRICS; NONHUMAN; PRIORITY JOURNAL; THROMBOCYTE ACTIVATION; THROMBOCYTE ADHESION; THROMBOGENESIS;

EID: 0030067990     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.ATV.16.1.56     Document Type: Article

References (54)

1. Baumgartner HR. The role of blood flow in platelet adhesion, fibrin deposition and formation of mural thrombi. Microvasc Res. 1973;5:167-179.
2. Turitto VT, Baumgartner HR. Effect of physical factors on platelet adherence to subendothelium. Thromb Diath Haemorrh. 1974;60(suppl):17-24.
3. Baumgartner HR. Effect of anticoagulation on the interaction of human platelets with subendothelium in flowing blood. Schweiz Med Wochenschr. 1976;106:1367-1368.
4. Muggli R, Baumgartner HR, Tschopp TB, Keller H. Automated microdensitometry and protein assays as a measure for platelet adhesion and aggregation on collagen-coated slides under controlled flow conditions. J Lab Clin Med. 1980;95:195-207.
5. Sakariassen KS, Aarts PAMM, de Groot PG, Houdijk WPM, Sixma JJ. A perfusion chamber developed to investigate platelet interaction in flowing blood with human vessel wall cells, their extracellular matrix, and purified components. J Lab Clin Med. 1983;102:522-535.
6. Sakariassen KS, Joss R, Muggli R, Kuhn H, Tschopp TB, Sage H, Baumgartner HR. Collagen type III induced ex vivo thrombogenesis in humans: role of platelets and leukocytes in deposition of fibrin. Arteriosclerosis. 1990;10:276-284.
7. Cazenave JP, Mulvihill JN, Huisman JG, van Aken WG. The use of monoclonal antibodies against platelet membrane glycoproteins to measure platelet accumulation on artificial surfaces. In: Jolles G, Legrand Y, Nurden A, eds. Biology and Pathology of the Platelet: Vessel Wall Interactions. New York, NY: Academic Press;1987:375-381.
8. Badimon L, Turitto V, Rosemark JA, Badimon JJ, Fuster V. Characterization of tubular flow chamber for studying platelet interaction with biologic and prosthetic materials: deposition of Indium 111-labeled platelets on collagen, subendothelium, and expanded polytetrafluoroethylene. J Lab Clin Med. 1987;110:706-718.
9. Foot A, Beugelin T, Cazenave JP, Bantjes A, van Aken WG. Platelet deposition in a capillary perfusion model: quantitative and morphological aspects. Biomaterials. 1988;9:126-132.
10. Cadroy Y, Horbett TA, Hanson SR. Discrimination between platelet-mediated and coagulation-mediated mechanisms in a model of complex thrombus formation in vivo. J Lab Clin Med. 1989;113:436-448.
11. Kupinski JM, Miller JL. Identification of receptors for fibrinogen and von Willebrand factor mediating aggregation in guinea pig platelets. Thromb Res. 1986;43:335-344.
12. Kupinski JM, Miller JL. Synthesis by guinea pig megakaryocytes of platelet glycoprotein receptors for fibrinogen and von Willebrand factor. Thromb Res. 1986;43:345-352.
13. Burke SE, Lefer AM, Nicolaou KC, Smith GM, Smith B. Responsiveness of platelets and coronary arteries from different species to synthetic thromboxane and prostaglandin endoperoxide analogues. Br J Pharmacol. 1983;78:287-292.
14. Roux S, Carteaux JP, Hess P, Favilene L, Clozel JP. Experimental carotid thrombosis in the guinea pig. Thromb Haemost. 1994;71:252-256.
15. 2 in reocclusion after thrombolysis. Thromb Haemost. 1995;73:683-688.
16. Alig L, Edenhofer A, Hadvary P, Huerzeler M, Knopp D, Mueller M, Steiner B, Trzeciak A, Weller T. Low molecular weight, nonpeptidic fibrinogen receptor antagonists. J Med Chem. 1992;35:4393-4407.
17. Hill RJ, Harper E. Quantitation of type I and III collagens in human tissue samples and cell culture by cyanogen bromide peptide analysis. Anal Biochem. 1984;141:83-93.
18. Bruns RR, Gross J. High resolution analysis of the quarter stagger model of the collagen fibril. Biopolymers. 1977;13:931-941.
19. 125I-containing acylating agent. Biochem J. 1973;133:529-539.
20. Dowell EMM, Trump BJ. Histological fixatives suitable for diagnostic light and electron microscopy. Arch Pathol Lab Med. 1976;100:405-414.
21. Sakariassen KS, Kuhn H, Muggli R, Baumgartner HR. Growth and stability of thrombi in flowing citrated blood: assessment of plateletsurface interactions with computer-assisted morphometry. Thromb Haemost. 1988;60:392-398.
22. Bergqvist D, Arfors KE. Growth rate and volume of haemostatic plugs in the mesentery of normal and thrombocytopenic rabbits. Thromb Res. 1974;4:77-87.
23. Arfors KE, Bergqvist D. Influence of blood flow velocity on experimental haemostatic plug formation. Thromb Res. 1974;4:454-461.
24. Sakariassen KS, Bolhuis PA, Sixma JJ. Human blood platelet adhesion to artery subendothelium is mediated by factor VIII-von Willebrand factor bound to the subendothelium. Nature. 1979;279:636-638.
25. Houdijk WPM, Sakariassen KS, Nievelstein PFEM, Sixma JJ. Role of factor VIII-von Willebrand factor and fibronectin in the interaction of platelets in flowing blood with monomeric and fibrillar human collagen types I and III. J Clin Invest. 1985;75:531-540.
26. Weiss HJ, Turitto VT, Baumgartner HR. Platelet adhesion and thrombus formation on subendothelium in platelets deficient in glycoproteins IIb/IIIa, Ib, and storage granules. Blood. 1986;67:322-330.
27. Fressinaud E, Baruch D, Girma JP, Sakariassen KS, Baumgartner HR, Meyer D. von Willebrand factor-mediated platelet adhesion to collagen involves platelet membrane glycoprotein IIb/IIIa as well as glycoprotein Ib. J Lab Clin Med. 1988;112:58-67.
28. Ruggeri ZM, Bader R, De Marco L. Glanzmann thrombasthenia: deficient binding of von Willebrand factor to thrombin-stimulated platelets. Proc Natl Acad Sci USA. 1982;79:6038-6041.
29. Pischel KD, Hemler ME, Huang C, Bluestein HG, Woods VL. Use of the monoclonal antibody 12F1 to characterize the differentiation antigen VLA-2. J Immunol. 1987;138:226-233.
30. Pischel KD, Bluestein HG, Woods VL Jr. Platelet glycoproteins Ia, Ic, and IIa are physicochemically indistinguishable from the very late activation antigens adhesion-related proteins of lymphocytes and other cell types. J Clin Invest. 1988;81:505-513.
31. Gralnick HR, McKeown LP, Williams SB, Lawrence JB, Shafer BC, Kramer WS, Hansmann KE, Vail ML, Magruder LE. A murinc monoclonal antibody that identifies a 157/130 kDa platelet-collagen receptor. Circulation. 1988;78(suppl II):308. Abstract.
32. ++-dependent adhesion of platelets to collagen. J Cell Biol. 1989;108:1917-1924.
33. Nieuwenhuis HK, Akkerman JW, Houdijk WPM, Sixma JJ. Human blood platelets showing no response to collagen fail to express surface glycoprotein Ia. Nature. 1985;318:470-472.
34. Nieuwenhuis HK, Sakariassen KS, Houdijk WPM, Nievelstein PFEM, Sixma JJ. Deficiency of platelet membrane glycoprotein la associated with a decreased platelet adhesion to subendothelium: a defect in platelet spreading. Blood. 1986;68:692-695.
35. Coller BS, Beer JH, Scudder LE, Steinberg MH. Collagen-platelet interactions: evidence for a direct interaction of collagen with platelet GPIa/IIa and an interaction with platelet GPIIb/IIIa mediated by adhesive proteins. Blood. 1989;74:182-192.
36. 1-Integrin). Blood. 1994;83:1244-1250.
37. Weiss HJ, Turitto VT, Baumgartner HR. Effect of shear rate on platelet interaction with subendothelium in citrated and native blood: shear-dependent decrease of adhesion in von Willebrand's disease and the Bernard-Soulier syndrome. J Lab Clin Med. 1978;92:750-764.
38. Weiss HJ. Role of von Willebrand factor in platelet adhesion. In: Zimmerman TS, Ruggeri ZM, eds. Coagulation and Bleeding Disorders: the Role of Factor VIII and von Willebrand Factor. New York, NY: Marcel Dekker Inc; 1989:195-213.
39. Weiss HJ. von Willebrand factor and platelet function. Ann NY Acad Sci. 1991;614:125-137.
40. 3) mediated by fibrinogen and glycoprotein Ib-von Willebrand factor. J Biol Chem. 1992;267:11300-11306.
41. Kroll MH, Harris TS, Moake JL, Handin RI, Schafer AI. von Willebrand factor binding to platelet GPIb initiates signals for platelet activation. J Clin Invest. 1991;88:1568-1573.
42. Coller BS, Peerschke EI, Scudder LE, Sullivan CA. A murine monoclonal antibody that completely blocks the binding of fibrinogen to platelets produces a thrombasthenic-like state in normal platelets and binds to glycoproteins IIb and/or IIIa. J Clin Invest. 1983;72:325-338.
43. 2 fragments of a monoclonal antibody to the platelet glycoprotein IIb/IIIa receptor. Blood. 1985;66:1456-1459.
44. Sakariassen KS, Baumgartner HR. Axial dependence of plateletcollagen interactions in flowing blood: upstream thrombus growth impairs downstream platelet adhesion. Arteriosclerosis. 1989;9:33-42.
45. Badimon L, Lassila R, Badimon J, Vallabhalosula S, Chesebro J, Fuster V. Residual thrombus is more thrombogenic than severely damaged vessel wall. Circulation. 1988;78(suppl II):II-119. Abstract.
46. Azzam K, Garfinkel LI, Bal dit Sollier C, Cisse-Thiam M, Drouet L. Antithrombotic effect of a recombinant von Willebrand factor, VCL, on nitrogen laser-induced thrombus formation in guinea pig mesenteric arteries. Thromb Haemost. 1995;73:318-323.
47. Turner NA, Moake JL, Kamat SG, Schafer AI, Kleiman NS, Jordan R, McIntire LV. Comparative real-time effects on platelet adhesion and aggregation under flowing conditions of in vivo aspirin, heparin, and monoclonal antibody fragment against glycoprotein IIb-IIIa. Circulation. 1995;91:1354-1362.
48. Roald HE, Sakariassen KS. Axial dependence of collagen-induced thrombus formation in flowing non-anticoagulated human blood: anti-platelet drugs impair thrombus growth and increase plateletcollagen adhesion. Thromb Haemost. 1995;73:126-131.
49. Weiss HJ, Turitto VT, Baumgartner HR. Further evidence that glycoprotein IIb-IIIa mediates platelet spreading on subendothelium. Thromb Haemost. 1991;65:202-205.
50. Lawrence JB, Gralnick HR. Monoclonal antibodies to the glycoprotein IIb-IIIa epitopes involved in adhesive protein binding: effects on platelet spreading and ultrastructure on human arterial subendothelium. J Lab Clin Med. 1987;109:495-503.
51. EPIC Investigators. Use of a monoclonal antibody directed against the platelet glycoprotein IIb/IIIa receptor in high-risk coronary angioplasty. N Engl J Med. 1994;330:956-961.
52. Bird RB, Stewart WE, Lightfoot EN. Transport Phenomena. New York, NY: John Wiley & Sons; 1960.
53. Goldsmith HL, Turitto VT. Rheological aspects of thrombosis and haemostasis: basic principles and applications. Thromb Haemost. 1986;55:415-435.
54. 2+ antagonist. Nippon Yakurigaku Zasshi. 1992;100:109-116.