Treatment of elderly primary insomnia patients with EVT 201 improves sleep initiation, sleep maintenance, and daytime sleepiness

Sleep Medicine

Volumn 11, Issue 1, 2010, Pages 23-30

  Walsh, James K ^a   Salkeld, Lynette ^b   Knowles, Lisa J ^c   Tasker, Tim ^c   Hunneyball, Ian M ^c  

^a ST LUKE S HOSPITAL   (United States)

^b Constella Group Ltd ^*  (United Kingdom)

^c Evotec Neurosciences GmbH   (Germany)

Author keywords

Elderly; EVT 201; Hypnotic; Partial GABAA agonist; Primary insomnia; Sleepiness

Indexed keywords

BENZODIAZEPINE; EVT 201; PLACEBO; UNCLASSIFIED DRUG;

AGED; ARTICLE; BALANCE DISORDER; BEDTIME DOSAGE; CLINICAL ASSESSMENT; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; COUGHING; DAYTIME SOMNOLENCE; DIAGNOSTIC AND STATISTICAL MANUAL OF MENTAL DISORDERS; DIARRHEA; DIZZINESS; DOSE RESPONSE; DOUBLE BLIND PROCEDURE; DRUG DOSE COMPARISON; DRUG DOSE REDUCTION; DRUG EFFICACY; DRUG ELIMINATION; DRUG HALF LIFE; FEMALE; GAIT DISORDER; HEADACHE; HUMAN; INSOMNIA; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; POLYSOMNOGRAPHY; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SLEEP PATTERN; SLEEP TIME; SLEEP WAKING CYCLE; SOMNOLENCE;

AGED; AGED, 80 AND OVER; BENZODIAZEPINES; CIRCADIAN RHYTHM; DOSE-RESPONSE RELATIONSHIP, DRUG; DOUBLE-BLIND METHOD; FEMALE; HUMANS; HYPNOTICS AND SEDATIVES; MALE; NEUROPSYCHOLOGICAL TESTS; POLYSOMNOGRAPHY; RECEPTORS, GABA-A; SLEEP INITIATION AND MAINTENANCE DISORDERS; TREATMENT OUTCOME; WAKEFULNESS;

EID: 73149114630     PISSN: 13899457     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.sleep.2009.07.012     Document Type: Article

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