The partial positive allosteric GABAA receptor modulator EVT 201 is efficacious and safe in the treatment of adult primary insomnia patients

Sleep Medicine

Volumn 10, Issue 8, 2009, Pages 859-864

  Walsh, James K ^a   Thacker, Steve ^b   Knowles, Lisa J ^c   Tasker, Tim ^c   Hunneyball, Ian M ^c  

^a ST LUKE S HOSPITAL   (United States)

^b Constella Group Ltd ^*  (United Kingdom)

^c EVOTEC UK LTD   (United Kingdom)

Author keywords

EVT 201; Hypnotic medication; Partial GABAA agonist; Primary insomnia; Sleep latency; Sleep maintenance

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR STIMULATING AGENT; EVT 201; PLACEBO; UNCLASSIFIED DRUG;

ADULT; ALERTNESS; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DIAGNOSTIC AND STATISTICAL MANUAL OF MENTAL DISORDERS; DIZZINESS; DOUBLE BLIND PROCEDURE; DRUG DOSE COMPARISON; DRUG EFFICACY; DRUG SAFETY; DRUG WITHDRAWAL; ELECTROCARDIOGRAPHY; FEMALE; HEADACHE; HEALTH CARE FACILITY; HUMAN; INFECTION; INSOMNIA; LABORATORY TEST; LATENT PERIOD; LATIN SQUARE DESIGN; MAJOR CLINICAL STUDY; MALE; MEDICAL DOCUMENTATION; MULTICENTER STUDY; NEUTROPENIA; PHASE 2 CLINICAL TRIAL; PHYSICAL EXAMINATION; POLYSOMNOGRAPHY; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SEDATION; SELF REPORT; SIDE EFFECT; SLEEP STAGE; SLEEP TIME; SLEEP WAKING CYCLE; SOMNOLENCE; TREATMENT OUTCOME; UNITED STATES;

ADULT; CROSS-OVER STUDIES; FEMALE; GABA MODULATORS; HUMANS; MALE; MIDDLE AGED; PATIENT SATISFACTION; POLYSOMNOGRAPHY; SLEEP; SLEEP INITIATION AND MAINTENANCE DISORDERS;

EID: 68749110579     PISSN: 13899457     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.sleep.2008.10.005     Document Type: Article

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