A possible mechanism for the decrease in serum thyroxine level by a 2,3,7,8-tetrachlorodibenzo-p-dioxin-like polychlorinated biphenyl congener, 3,3′,4,4′,5-pentachlorobiphenyl in mice

Drug Metabolism and Disposition

Volumn 38, Issue 1, 2010, Pages 150-156

  Kato, Yoshihisa ^a   Haraguchi, Koichi ^b   Kubota, Makiko ^c   Seto, Yoshiki ^c   Okura, Takashi ^d   Ikushiro, Shin Ichi ^e   Koga, Nobuyuki ^f   Yamada, Shizuo ^c   Degawa, Masakuni ^c  

^a TOKUSHIMA BUNRI UNIVERSITY   (Japan)

^b DAIICHI UNIVERSITY OF PHARMACY   (Japan)

^c UNIVERSITY OF SHIZUOKA   (Japan)

^d TEIKYO UNIVERSITY   (Japan)

^e TOYAMA PREFECTURAL UNIVERSITY   (Japan)

^f NAKAMURA GAKUEN UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; 3,3',4,4',5 PENTACHLOROBIPHENYL; GLUCURONIDE; GLUCURONOSYLTRANSFERASE; THYROXINE; URIDINE DIPHOSPHATE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG STRUCTURE; GLUCURONIDATION; LIVER HYPERTROPHY; LIVER WEIGHT; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; THYROXINE BLOOD LEVEL;

ANIMALS; BILE; BLOOD PROTEINS; CYTOCHROME P-450 ENZYME SYSTEM; ENZYME INDUCTION; ESTROGEN ANTAGONISTS; GLUCURONIC ACID; GLUCURONOSYLTRANSFERASE; ISOENZYMES; LIVER; MICE; MICE, INBRED C57BL; MICE, INBRED DBA; MICROSOMES, LIVER; ORGAN SIZE; POLYCHLORINATED BIPHENYLS; PROTEIN BINDING; TETRACHLORODIBENZODIOXIN; THYROTROPIN; THYROXINE; TISSUE DISTRIBUTION;

MUS;

EID: 73149105082     PISSN: 00909556     EISSN: 1521009X     Source Type: Journal    
DOI: 10.1124/dmd.109.029348     Document Type: Article

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