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Volumn 10, Issue , 2009, Pages

Characterisation of CYP2C8, CYP2C9 and CYP2C19 polymorphisms in a Ghanaian population

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450 2C19; CYTOCHROME P450 2C8; CYTOCHROME P450 2C9; CYP2C19 PROTEIN, HUMAN; CYP2C8 PROTEIN, HUMAN; CYP2C9 PROTEIN, HUMAN; UNSPECIFIC MONOOXYGENASE;

EID: 73149102765     PISSN: None     EISSN: 14712350     Source Type: Journal    
DOI: 10.1186/1471-2350-10-124     Document Type: Article
Times cited : (64)

References (43)
  • 1
    • 0036219998 scopus 로고    scopus 로고
    • Common allelic variants of cytochrome P4503A4 and their prevalence in different populations
    • 10.1097/00008571-200203000-00006, 11875366
    • Lamba JK, Lin YS, Thummel K, Daly A, Watkins PB, Strom S, Zhang J, Schuetz EG. Common allelic variants of cytochrome P4503A4 and their prevalence in different populations. Pharmacogenetics 2002, 12(2):121-132. 10.1097/00008571-200203000-00006, 11875366.
    • (2002) Pharmacogenetics , vol.12 , Issue.2 , pp. 121-132
    • Lamba, J.K.1    Lin, Y.S.2    Thummel, K.3    Daly, A.4    Watkins, P.B.5    Strom, S.6    Zhang, J.7    Schuetz, E.G.8
  • 2
    • 33646205301 scopus 로고    scopus 로고
    • Interethnic and intraethnic variability of CYP2C8 and CYP2C9 polymorphisms in healthy individuals
    • Garcia-Martin E, Martinez C, Ladero JM, Agundez JA. Interethnic and intraethnic variability of CYP2C8 and CYP2C9 polymorphisms in healthy individuals. Mol Diagn Ther 2006, 10(1):29-40.
    • (2006) Mol Diagn Ther , vol.10 , Issue.1 , pp. 29-40
    • Garcia-Martin, E.1    Martinez, C.2    Ladero, J.M.3    Agundez, J.A.4
  • 3
    • 0034792584 scopus 로고    scopus 로고
    • Clinical relevance of genetic polymorphisms in the human CYP2C subfamily
    • 10.1046/j.0306-5251.2001.01499.x, 2014584, 11678778
    • Goldstein JA. Clinical relevance of genetic polymorphisms in the human CYP2C subfamily. Br J Clin Pharmacol 2001, 52(4):349-355. 10.1046/j.0306-5251.2001.01499.x, 2014584, 11678778.
    • (2001) Br J Clin Pharmacol , vol.52 , Issue.4 , pp. 349-355
    • Goldstein, J.A.1
  • 4
    • 0141791128 scopus 로고    scopus 로고
    • Cytochrome P450 enzyme polymorphisms and adverse drug reactions
    • 10.1016/S0300-483X(03)00247-6, 14511900
    • Pirmohamed M, Park BK. Cytochrome P450 enzyme polymorphisms and adverse drug reactions. Toxicology 2003, 192(1):23-32. 10.1016/S0300-483X(03)00247-6, 14511900.
    • (2003) Toxicology , vol.192 , Issue.1 , pp. 23-32
    • Pirmohamed, M.1    Park, B.K.2
  • 6
    • 0034791777 scopus 로고    scopus 로고
    • Polymorphisms in human CYP2C8 decrease metabolism of the anticancer drug paclitaxel and arachidonic acid
    • 10.1097/00008571-200110000-00006, 11668219
    • Dai D, Zeldin DC, Blaisdell JA, Chanas B, Coulter SJ, Ghanayem BI, Goldstein JA. Polymorphisms in human CYP2C8 decrease metabolism of the anticancer drug paclitaxel and arachidonic acid. Pharmacogenetics 2001, 11(7):597-607. 10.1097/00008571-200110000-00006, 11668219.
    • (2001) Pharmacogenetics , vol.11 , Issue.7 , pp. 597-607
    • Dai, D.1    Zeldin, D.C.2    Blaisdell, J.A.3    Chanas, B.4    Coulter, S.J.5    Ghanayem, B.I.6    Goldstein, J.A.7
  • 7
    • 1842558550 scopus 로고    scopus 로고
    • Allelic variants of cytochromes P450 2C modify the risk for acute myocardial infarction
    • 10.1097/00008571-200312000-00002, 14646690
    • Yasar U, Bennet AM, Eliasson E, Lundgren S, Wiman B, De Faire U, Rane A. Allelic variants of cytochromes P450 2C modify the risk for acute myocardial infarction. Pharmacogenetics 2003, 13(12):715-720. 10.1097/00008571-200312000-00002, 14646690.
    • (2003) Pharmacogenetics , vol.13 , Issue.12 , pp. 715-720
    • Yasar, U.1    Bennet, A.M.2    Eliasson, E.3    Lundgren, S.4    Wiman, B.5    De Faire, U.6    Rane, A.7
  • 8
    • 0031841377 scopus 로고    scopus 로고
    • Cytochrome P4502C9: an enzyme of major importance in human drug metabolism
    • 10.1046/j.1365-2125.1998.00721.x, 1873650, 9663807
    • Miners JO, Birkett DJ. Cytochrome P4502C9: an enzyme of major importance in human drug metabolism. Br J Clin Pharmacol 1998, 45(6):525-538. 10.1046/j.1365-2125.1998.00721.x, 1873650, 9663807.
    • (1998) Br J Clin Pharmacol , vol.45 , Issue.6 , pp. 525-538
    • Miners, J.O.1    Birkett, D.J.2
  • 9
    • 0037131892 scopus 로고    scopus 로고
    • CYP2C9 allelic variants: ethnic distribution and functional significance
    • 10.1016/S0169-409X(02)00076-5, 12406644
    • Xie HG, Prasad HC, Kim RB, Stein CM. CYP2C9 allelic variants: ethnic distribution and functional significance. Adv Drug Deliv Rev 2002, 54(10):1257-1270. 10.1016/S0169-409X(02)00076-5, 12406644.
    • (2002) Adv Drug Deliv Rev , vol.54 , Issue.10 , pp. 1257-1270
    • Xie, H.G.1    Prasad, H.C.2    Kim, R.B.3    Stein, C.M.4
  • 11
    • 13844315559 scopus 로고    scopus 로고
    • CYP2C9 gene variants, drug dose, and bleeding risk in warfarin-treated patients: a HuGEnet systematic review and meta-analysis
    • 10.1002/ajmg.a.30391, 15714076
    • Sanderson S, Emery J, Higgins J. CYP2C9 gene variants, drug dose, and bleeding risk in warfarin-treated patients: a HuGEnet systematic review and meta-analysis. Genet Med 2005, 7(2):97-104. 10.1002/ajmg.a.30391, 15714076.
    • (2005) Genet Med , vol.7 , Issue.2 , pp. 97-104
    • Sanderson, S.1    Emery, J.2    Higgins, J.3
  • 12
    • 0034978572 scopus 로고    scopus 로고
    • The effect of genetic polymorphism of cytochrome P450 CYP2C9 on phenytoin dose requirement
    • 10.1097/00008571-200106000-00002, 11434505
    • Weide J, Steijns LS, van Weelden MJ, de Haan K. The effect of genetic polymorphism of cytochrome P450 CYP2C9 on phenytoin dose requirement. Pharmacogenetics 2001, 11(4):287-291. 10.1097/00008571-200106000-00002, 11434505.
    • (2001) Pharmacogenetics , vol.11 , Issue.4 , pp. 287-291
    • Weide, J.1    Steijns, L.S.2    van Weelden, M.J.3    de Haan, K.4
  • 13
    • 77955382935 scopus 로고    scopus 로고
    • Whatman FTA Protocol
    • Whatman FTA Protocol. , http://www.kirkhousetrust.org/Docs/FTAProtocolBD08.pdf
  • 14
    • 0036889666 scopus 로고    scopus 로고
    • CYP2C8 polymorphisms in Caucasians and their relationship with paclitaxel 6alpha-hydroxylase activity in human liver microsomes
    • 10.1016/S0006-2952(02)01354-0, 12429347
    • Bahadur N, Leathart JB, Mutch E, Steimel-Crespi D, Dunn SA, Gilissen R, Houdt JV, Hendrickx J, Mannens G, Bohets H. CYP2C8 polymorphisms in Caucasians and their relationship with paclitaxel 6alpha-hydroxylase activity in human liver microsomes. Biochem Pharmacol 2002, 64(11):1579-1589. 10.1016/S0006-2952(02)01354-0, 12429347.
    • (2002) Biochem Pharmacol , vol.64 , Issue.11 , pp. 1579-1589
    • Bahadur, N.1    Leathart, J.B.2    Mutch, E.3    Steimel-Crespi, D.4    Dunn, S.A.5    Gilissen, R.6    Houdt, J.V.7    Hendrickx, J.8    Mannens, G.9    Bohets, H.10
  • 15
    • 0344512432 scopus 로고    scopus 로고
    • Genetic polymorphisms of CYP2C9 and CYP2C19 in the Beninese and Belgian populations
    • 10.1046/j.1365-2125.2003.01937.x, 1884305, 14616425
    • Allabi AC, Gala JL, Desager JP, Heusterspreute M, Horsmans Y. Genetic polymorphisms of CYP2C9 and CYP2C19 in the Beninese and Belgian populations. Br J Clin Pharmacol 2003, 56(6):653-657. 10.1046/j.1365-2125.2003.01937.x, 1884305, 14616425.
    • (2003) Br J Clin Pharmacol , vol.56 , Issue.6 , pp. 653-657
    • Allabi, A.C.1    Gala, J.L.2    Desager, J.P.3    Heusterspreute, M.4    Horsmans, Y.5
  • 16
    • 0035064871 scopus 로고    scopus 로고
    • Two single-tube tetra-primer assays to detect the CYP2C19*2 and *3 alleles of S-mephenytoin hydroxylase
    • Hersberger M, Marti-Jaun J, Rentsch K, Hanseler E. Two single-tube tetra-primer assays to detect the CYP2C19*2 and *3 alleles of S-mephenytoin hydroxylase. Clin Chem 2001, 47(4):772-774.
    • (2001) Clin Chem , vol.47 , Issue.4 , pp. 772-774
    • Hersberger, M.1    Marti-Jaun, J.2    Rentsch, K.3    Hanseler, E.4
  • 18
    • 25844438367 scopus 로고    scopus 로고
    • The Prevalence of CYP2C8, 2C9, 2J2, and soluble epoxide hydrolase polymorphisms in African Americans with hypertension
    • 10.1016/j.amjhyper.2005.04.019, 16202848
    • Dreisbach AW, Japa S, Sigel A, Parenti MB, Hess AE, Srinouanprachanh SL, Rettie AE, Kim H, Farin FM, Hamm LL. The Prevalence of CYP2C8, 2C9, 2J2, and soluble epoxide hydrolase polymorphisms in African Americans with hypertension. Am J Hypertens 2005, 18(10):1276-1281. 10.1016/j.amjhyper.2005.04.019, 16202848.
    • (2005) Am J Hypertens , vol.18 , Issue.10 , pp. 1276-1281
    • Dreisbach, A.W.1    Japa, S.2    Sigel, A.3    Parenti, M.B.4    Hess, A.E.5    Srinouanprachanh, S.L.6    Rettie, A.E.7    Kim, H.8    Farin, F.M.9    Hamm, L.L.10
  • 19
    • 34447569316 scopus 로고    scopus 로고
    • Amodiaquine metabolism is impaired by common polymorphisms in CYP2C8: implications for malaria treatment in Africa
    • 10.1038/sj.clpt.6100122, 17361129
    • Parikh S, Ouedraogo JB, Goldstein JA, Rosenthal PJ, Kroetz DL. Amodiaquine metabolism is impaired by common polymorphisms in CYP2C8: implications for malaria treatment in Africa. Clin Pharmacol Ther 2007, 82(2):197-203. 10.1038/sj.clpt.6100122, 17361129.
    • (2007) Clin Pharmacol Ther , vol.82 , Issue.2 , pp. 197-203
    • Parikh, S.1    Ouedraogo, J.B.2    Goldstein, J.A.3    Rosenthal, P.J.4    Kroetz, D.L.5
  • 22
    • 1842636202 scopus 로고    scopus 로고
    • Development and evaluation of a rapid and reliable method for cytochrome P450 2C8 genotyping
    • Weise A, Grundler S, Zaumsegel D, Klotzek M, Grondahl B, Forst T, Pfutzner A. Development and evaluation of a rapid and reliable method for cytochrome P450 2C8 genotyping. Clin Lab 2004, 50(3-4):141-148.
    • (2004) Clin Lab , vol.50 , Issue.3-4 , pp. 141-148
    • Weise, A.1    Grundler, S.2    Zaumsegel, D.3    Klotzek, M.4    Grondahl, B.5    Forst, T.6    Pfutzner, A.7
  • 24
    • 0034799608 scopus 로고    scopus 로고
    • Genetic polymorphism of cytochrome P450 2C9 in a Caucasian and a black African population
    • 10.1046/j.0306-5251.2001.01460.x, 2014581, 11678789
    • Scordo MG, Aklillu E, Yasar U, Dahl ML, Spina E, Ingelman-Sundberg M. Genetic polymorphism of cytochrome P450 2C9 in a Caucasian and a black African population. Br J Clin Pharmacol 2001, 52(4):447-450. 10.1046/j.0306-5251.2001.01460.x, 2014581, 11678789.
    • (2001) Br J Clin Pharmacol , vol.52 , Issue.4 , pp. 447-450
    • Scordo, M.G.1    Aklillu, E.2    Yasar, U.3    Dahl, M.L.4    Spina, E.5    Ingelman-Sundberg, M.6
  • 25
    • 0030858832 scopus 로고    scopus 로고
    • The R144C change in the CYP2C9*2 allele alters interaction of the cytochrome P450 with NADPH:cytochrome P450 oxidoreductase
    • 10.1097/00008571-199706000-00005, 9241660
    • Crespi CL, Miller VP. The R144C change in the CYP2C9*2 allele alters interaction of the cytochrome P450 with NADPH:cytochrome P450 oxidoreductase. Pharmacogenetics 1997, 7(3):203-210. 10.1097/00008571-199706000-00005, 9241660.
    • (1997) Pharmacogenetics , vol.7 , Issue.3 , pp. 203-210
    • Crespi, C.L.1    Miller, V.P.2
  • 26
    • 0034150775 scopus 로고    scopus 로고
    • CYP2C9 Ile359 and Leu359 variants: enzyme kinetic study with seven substrates
    • 10.1097/00008571-200003000-00001, 10761997
    • Takanashi K, Tainaka H, Kobayashi K, Yasumori T, Hosakawa M, Chiba K. CYP2C9 Ile359 and Leu359 variants: enzyme kinetic study with seven substrates. Pharmacogenetics 2000, 10(2):95-104. 10.1097/00008571-200003000-00001, 10761997.
    • (2000) Pharmacogenetics , vol.10 , Issue.2 , pp. 95-104
    • Takanashi, K.1    Tainaka, H.2    Kobayashi, K.3    Yasumori, T.4    Hosakawa, M.5    Chiba, K.6
  • 27
    • 0242543259 scopus 로고    scopus 로고
    • Clinical relevance of genetic polymorphisms in the human CYP2C9 gene
    • 10.1046/j.1365-2362.33.s2.6.x, 14641553
    • Schwarz UI. Clinical relevance of genetic polymorphisms in the human CYP2C9 gene. Eur J Clin Invest 2003, 33(Suppl 2):23-30. 10.1046/j.1365-2362.33.s2.6.x, 14641553.
    • (2003) Eur J Clin Invest , vol.33 , Issue.SUPPL 2 , pp. 23-30
    • Schwarz, U.I.1
  • 28
    • 0036263813 scopus 로고    scopus 로고
    • Cytochrome P450 2C9 polymorphisms: a comprehensive review of the in-vitro and human data
    • 10.1097/00008571-200204000-00010, 11927841
    • Lee CR, Goldstein JA, Pieper JA. Cytochrome P450 2C9 polymorphisms: a comprehensive review of the in-vitro and human data. Pharmacogenetics 2002, 12(3):251-263. 10.1097/00008571-200204000-00010, 11927841.
    • (2002) Pharmacogenetics , vol.12 , Issue.3 , pp. 251-263
    • Lee, C.R.1    Goldstein, J.A.2    Pieper, J.A.3
  • 29
    • 0029949970 scopus 로고    scopus 로고
    • Individual sulfonylureas and serious hypoglycemia in older people
    • Shorr RI, Ray WA, Daugherty JR, Griffin MR. Individual sulfonylureas and serious hypoglycemia in older people. J Am Geriatr Soc 1996, 44(7):751-755.
    • (1996) J Am Geriatr Soc , vol.44 , Issue.7 , pp. 751-755
    • Shorr, R.I.1    Ray, W.A.2    Daugherty, J.R.3    Griffin, M.R.4
  • 30
    • 0033230718 scopus 로고    scopus 로고
    • Major bleeding after hospitalization for deep-venous thrombosis
    • 10.1016/S0002-9343(99)00267-3, 10569295
    • White RH, Beyth RJ, Zhou H, Romano PS. Major bleeding after hospitalization for deep-venous thrombosis. Am J Med 1999, 107(5):414-424. 10.1016/S0002-9343(99)00267-3, 10569295.
    • (1999) Am J Med , vol.107 , Issue.5 , pp. 414-424
    • White, R.H.1    Beyth, R.J.2    Zhou, H.3    Romano, P.S.4
  • 31
    • 0028044085 scopus 로고
    • Identification of a new genetic defect responsible for the polymorphism of (S)-mephenytoin metabolism in Japanese
    • De Morais SM, Wilkinson GR, Blaisdell J, Meyer UA, Nakamura K, Goldstein JA. Identification of a new genetic defect responsible for the polymorphism of (S)-mephenytoin metabolism in Japanese. Mol Pharmacol 1994, 46(4):594-598.
    • (1994) Mol Pharmacol , vol.46 , Issue.4 , pp. 594-598
    • De Morais, S.M.1    Wilkinson, G.R.2    Blaisdell, J.3    Meyer, U.A.4    Nakamura, K.5    Goldstein, J.A.6
  • 32
    • 0028260641 scopus 로고
    • The major genetic defect responsible for the polymorphism of S-mephenytoin metabolism in humans
    • de Morais SM, Wilkinson GR, Blaisdell J, Nakamura K, Meyer UA, Goldstein JA. The major genetic defect responsible for the polymorphism of S-mephenytoin metabolism in humans. J Biol Chem 1994, 269(22):15419-15422.
    • (1994) J Biol Chem , vol.269 , Issue.22 , pp. 15419-15422
    • de Morais, S.M.1    Wilkinson, G.R.2    Blaisdell, J.3    Nakamura, K.4    Meyer, U.A.5    Goldstein, J.A.6
  • 33
    • 0030904031 scopus 로고    scopus 로고
    • Frequencies of the defective CYP2C19 alleles responsible for the mephenytoin poor metabolizer phenotype in various Oriental, Caucasian, Saudi Arabian and American black populations
    • 10.1097/00008571-199702000-00008, 9110363
    • Goldstein JA, Ishizaki T, Chiba K, de Morais SM, Bell D, Krahn PM, Evans DA. Frequencies of the defective CYP2C19 alleles responsible for the mephenytoin poor metabolizer phenotype in various Oriental, Caucasian, Saudi Arabian and American black populations. Pharmacogenetics 1997, 7(1):59-64. 10.1097/00008571-199702000-00008, 9110363.
    • (1997) Pharmacogenetics , vol.7 , Issue.1 , pp. 59-64
    • Goldstein, J.A.1    Ishizaki, T.2    Chiba, K.3    de Morais, S.M.4    Bell, D.5    Krahn, P.M.6    Evans, D.A.7
  • 34
    • 0035039209 scopus 로고    scopus 로고
    • Genetic polymorphism of CYP2D6 and CYP2C19 in east- and southern African populations including psychiatric patients
    • 10.1007/s002280100282, 11372584
    • Dandara C, Masimirembwa CM, Magimba A, Sayi J, Kaaya S, Sommers DK, Snyman JR, Hasler JA. Genetic polymorphism of CYP2D6 and CYP2C19 in east- and southern African populations including psychiatric patients. Eur J Clin Pharmacol 2001, 57(1):11-17. 10.1007/s002280100282, 11372584.
    • (2001) Eur J Clin Pharmacol , vol.57 , Issue.1 , pp. 11-17
    • Dandara, C.1    Masimirembwa, C.M.2    Magimba, A.3    Sayi, J.4    Kaaya, S.5    Sommers, D.K.6    Snyman, J.R.7    Hasler, J.A.8
  • 35
    • 0041410075 scopus 로고    scopus 로고
    • Polymorphisms of drug-metabolizing enzymes CYP2C9, CYP2C19, CYP2D6, CYP1A1, NAT2 and of P-glycoprotein in a Russian population
    • 10.1007/s00228-003-0606-2, 12879168
    • Gaikovitch EA, Cascorbi I, Mrozikiewicz PM, Brockmoller J, Frotschl R, Kopke K, Gerloff T, Chernov JN, Roots I. Polymorphisms of drug-metabolizing enzymes CYP2C9, CYP2C19, CYP2D6, CYP1A1, NAT2 and of P-glycoprotein in a Russian population. Eur J Clin Pharmacol 2003, 59(4):303-312. 10.1007/s00228-003-0606-2, 12879168.
    • (2003) Eur J Clin Pharmacol , vol.59 , Issue.4 , pp. 303-312
    • Gaikovitch, E.A.1    Cascorbi, I.2    Mrozikiewicz, P.M.3    Brockmoller, J.4    Frotschl, R.5    Kopke, K.6    Gerloff, T.7    Chernov, J.N.8    Roots, I.9
  • 36
    • 0028590127 scopus 로고
    • Biochemistry and molecular biology of the human CYP2C subfamily
    • 10.1097/00008571-199412000-00001, 7704034
    • Goldstein JA, de Morais SM. Biochemistry and molecular biology of the human CYP2C subfamily. Pharmacogenetics 1994, 4(6):285-299. 10.1097/00008571-199412000-00001, 7704034.
    • (1994) Pharmacogenetics , vol.4 , Issue.6 , pp. 285-299
    • Goldstein, J.A.1    de Morais, S.M.2
  • 38
    • 0037330517 scopus 로고    scopus 로고
    • Genetic polymorphisms in MDR1 and CYP3A4 genes in Asians and the influence of MDR1 haplotypes on cyclosporin disposition in heart transplant recipients
    • 10.1097/00008571-200302000-00005, 12563178
    • Chowbay B, Cumaraswamy S, Cheung YB, Zhou Q, Lee EJ. Genetic polymorphisms in MDR1 and CYP3A4 genes in Asians and the influence of MDR1 haplotypes on cyclosporin disposition in heart transplant recipients. Pharmacogenetics 2003, 13(2):89-95. 10.1097/00008571-200302000-00005, 12563178.
    • (2003) Pharmacogenetics , vol.13 , Issue.2 , pp. 89-95
    • Chowbay, B.1    Cumaraswamy, S.2    Cheung, Y.B.3    Zhou, Q.4    Lee, E.J.5
  • 39
    • 19244365359 scopus 로고    scopus 로고
    • Impact of polymorphisms of cytochrome-P450 isoenzymes 2C9, 2C19 and 2D6 on plasma concentrations and clinical effects of antidepressants in a naturalistic clinical setting
    • 10.1007/s00228-004-0766-8, 15168101
    • Grasmader K, Verwohlt PL, Rietschel M, Dragicevic A, Muller M, Hiemke C, Freymann N, Zobel A, Maier W, Rao ML. Impact of polymorphisms of cytochrome-P450 isoenzymes 2C9, 2C19 and 2D6 on plasma concentrations and clinical effects of antidepressants in a naturalistic clinical setting. Eur J Clin Pharmacol 2004, 60(5):329-336. 10.1007/s00228-004-0766-8, 15168101.
    • (2004) Eur J Clin Pharmacol , vol.60 , Issue.5 , pp. 329-336
    • Grasmader, K.1    Verwohlt, P.L.2    Rietschel, M.3    Dragicevic, A.4    Muller, M.5    Hiemke, C.6    Freymann, N.7    Zobel, A.8    Maier, W.9    Rao, M.L.10
  • 40
    • 0027248271 scopus 로고
    • Drug-related hospital admissions
    • Einarson TR. Drug-related hospital admissions. Ann Pharmacother 1993, 27(7-8):832-840.
    • (1993) Ann Pharmacother , vol.27 , Issue.7-8 , pp. 832-840
    • Einarson, T.R.1
  • 41
    • 0032522873 scopus 로고    scopus 로고
    • Incidence of adverse drug reactions in hospitalized patients: a meta-analysis of prospective studies
    • 10.1001/jama.279.15.1200, 9555760
    • Lazarou J, Pomeranz BH, Corey PN. Incidence of adverse drug reactions in hospitalized patients: a meta-analysis of prospective studies. Jama 1998, 279(15):1200-1205. 10.1001/jama.279.15.1200, 9555760.
    • (1998) Jama , vol.279 , Issue.15 , pp. 1200-1205
    • Lazarou, J.1    Pomeranz, B.H.2    Corey, P.N.3
  • 42
    • 33745674710 scopus 로고    scopus 로고
    • Pharmacogenetic screening for polymorphisms in drug-metabolizing enzymes and drug transporters in a Dutch population
    • Bosch TM, Doodeman VD, Smits PH, Meijerman I, Schellens JH, Beijnen JH. Pharmacogenetic screening for polymorphisms in drug-metabolizing enzymes and drug transporters in a Dutch population. Mol Diagn Ther 2006, 10(3):175-185.
    • (2006) Mol Diagn Ther , vol.10 , Issue.3 , pp. 175-185
    • Bosch, T.M.1    Doodeman, V.D.2    Smits, P.H.3    Meijerman, I.4    Schellens, J.H.5    Beijnen, J.H.6
  • 43
    • 0042318858 scopus 로고    scopus 로고
    • Allele and genotype frequency of CYP2C19 in a Tamilian population
    • 10.1046/j.1365-2125.2003.01883.x, 1884356, 12919183
    • Adithan C, Gerard N, Vasu S, Rosemary J, Shashindran CH, Krishnamoorthy R. Allele and genotype frequency of CYP2C19 in a Tamilian population. Br J Clin Pharmacol 2003, 56(3):331-333. 10.1046/j.1365-2125.2003.01883.x, 1884356, 12919183.
    • (2003) Br J Clin Pharmacol , vol.56 , Issue.3 , pp. 331-333
    • Adithan, C.1    Gerard, N.2    Vasu, S.3    Rosemary, J.4    Shashindran, C.H.5    Krishnamoorthy, R.6


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