Serum levels of ghrelin, tumor necrosis factor-α and interleukin-6 in infants and children with congenital heart disease

Journal of Tropical Pediatrics

Volumn 55, Issue 6, 2009, Pages 388-392

  Afify, Mohamed Farouk ^a   Mohamed, Gamal B ^a   El maboud, Mohamed Abd ^a   Abdel latif, Esmat A ^a  

^a MINIA UNIVERSITY   (Egypt)

Author keywords

Children; Congenital heart disease; Cytokines; Ghrelin

Indexed keywords

GHRELIN; INTERLEUKIN 6; TUMOR NECROSIS FACTOR ALPHA;

ANTHROPOMETRY; ARTERIAL TRUNK; ARTICLE; BODY MASS; CONGENITAL HEART DISEASE; CONTROLLED STUDY; CYANOSIS; CYTOKINE PRODUCTION; FALLOT TETRALOGY; FEMALE; GREAT VESSELS TRANSPOSITION; HEART ATRIUM SEPTUM DEFECT; HEART VENTRICLE SEPTUM DEFECT; HUMAN; MAJOR CLINICAL STUDY; MALE; PATENT DUCTUS ARTERIOSUS; TRICUSPID VALVE ATRESIA;

ANOXIA; CASE-CONTROL STUDIES; CHILD; CHILD, PRESCHOOL; CYANOSIS; EGYPT; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; GHRELIN; GROWTH DISORDERS; HEART DEFECTS, CONGENITAL; HUMANS; INFANT; INTERLEUKIN-6; MALE; MALNUTRITION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 73049098067     PISSN: 01426338     EISSN: 14653664     Source Type: Journal    
DOI: 10.1093/tropej/fmp036     Document Type: Article

References (33)

1. Van der Lely A, Tschop M, Heiman E. Biological, physiological, pathophysiological, and pharmacological aspects of ghrelin. Endocr Rev 2004;25:426-57.
2. Zou CC, Hung K, Liang K. Polymorphisms of the ghrelin/obestatin gene and ghrelin levels in Chinese children with short stature. Clin Endocrinol 2008;8:67-88.
3. Cummings DE, Shannon M. Roles for ghrelin in the regulation of appetite and body weight. Arch Surg 2003;138:389-96.
4. Ueno H, Yamaguchi H, Kangawa K. Ghrelin: a gastric peptide that regulates food intake and energy homeostasis. Regul Pept 2005;126:11-9.
5. Beutler B, Cerami A. Cachectin (tumor necrosis factor): a macrophage hormone governing cellular metabolism and inflammatory response. Endocr Rev 1988;9:57-66.
6. Tracey KJ, Cerami A. Tumor necrosis factor: a pleiotropic cytokine and therapeutic target. Ann Rev Med 1994;45:491-503.
7. Le J, Vilcek J. Interleukin 6: a multifunctional cytokine regulating immune reactions and the acute phase protein response. Lab Invest 1989;61:588-602.
8. Forchielli L, McColl R. Children with congenital heart disease: a nutrition challenge. Nutr Rev 1994;52: 348-53.
9. Nydegger A, Bines JE. Energy metabolism in infants with congenital heart disease. Nutrition 2006;22: 697-704.
10. Gingell RL, Hornung MG. Growth problems associated with congenital heart disease in infancy. In: Lebenthal E (ed). Textbook of Gastroenterology and Nutrition in Infancy. New York, NY, USA: Raven Press, 1989, 639-49.
11. da Silva VM, de Oliveira Lopes MV, de Araujo TL. Feeding difficulties and growth delay in children with hypoplastic left heart syndrome versus d-transposition of the great arteries. Pediatr Cardiol 2008;29:328-33.
12. El-Naggar M. Clinical assessment of growth and development. In: Pediatric Clinical Diagnosis, 5th edn. Cairo, Egypt: University Book Center, 2007, 56-8.
13. Krieger I. Growth failure and congenital heart disease. Am J Dis Child 1970;120:497-502.
14. Gilger M, Jensen C, Kessler B. Nutrition, growth, and the gastrointestinal system: basic knowledge for the pediatric cardiologist. In: Ganson A, Bricker JT, McNamara PG (eds). The Science and Practice of Pediatric Cardiology. Philadelphia: Lea & Febiger, 1990, 2354-70.
15. Unger R, DeKleermaeker M, Gidding SS. Improved weight gain with dietary intervention in congenital heart disease. Am J Dis Child 1992;146:1078-84.
16. Abad-Sinden A, Sutphen JL. Growth and nutrition. In: Allan DH, Gutgesell HP, Clark EB, et al. (eds). Moss and Adams' Heart Disease in Infants, Children, and Adolescents. Philadelphia, PA, USA: Lippincott Williams & Wilkins, 2001, 325-32.
17. Varan B, Tokel K, Yilmaz G. Malnutrition and growth failure in cyanotic and acyanotic congenital heart disease with and without pulmonary hypertension. Arch Dis Child 1999;81:49-52.
18. Cameron JW, Rosenthal A, Olson AD. Malnutrition in hospitalized children with congenital heart disease. Arch Pediatr Adolesc Med 1995;149:1098-102.
19. Leite HP, deCamargo Carvalho AC, Fisberg M. Nutritional status of children with congenital heart disease and left-to-right shunt: the importance of the presence of pulmonary hypertension. Arq Bras Cardiol 1995;65:403-7.
20. Linde LM, Dunn OJ, Schireson R. Growth in children with congenital heart disease. J Pediatr 1967;70:413-19.
21. Salzer HR, Haschke F, Wimmer M. Growth and nutritional intake of infants with congenital heart disease. Pediatr Cardiol 1989;10:17-23.
22. Soriano-Guillén L, Barrios V, Argente J. Physiopathological features and diagnostic utility of ghrelin protein in pediatrics. Anales de Pediatria 2004;61:5-7.
23. Whatmore AJ, Hall CM, Jones J. Ghrelin concentrations in healthy children and adolescents. Clin Endocrinol 2003;59:649-54.
24. Haqq AM, Farooqi IS, O'Rahilly S. Serum ghrelin levels are inversely correlated with body mass index, age, and insulin concentrations in normal children and are markedly increased in Prader-Willi syndrome. J Clin Endocrinol Metab 2003;88:174-8.
25. Baum D, Beck RQ, Haskell WL. Growth and tissue abnormalities in young people with cyanotic congenital heart disease receiving systemic-pulmonary artery shunts. Am J Cardiol 1983;52:349-52.
26. Dinleyici EC, Kilic Z, Buyukkaragoz B. Serum IGF-1, IGFBP-3 and growth hormone levels in children with congenital heart disease: relationship with nutritional status, cyanosis and left ventricular functions. Neuro Endocrinol Lett 2007;28:279-83.
27. Inui A. Cancer anorexia-cachexia syndrome: are neuropeptides the key? Cancer Res 1999;59:4493-501.
28. Kotler DP. Cachexia. Ann Intern Med 2000; 133:622-34.
29. Freeman LM, Roubenoff R. The nutritional implications of cardiac cachexia. Nutr Rev 1994;52:340-7.
30. Morrison WL, Edwards RHT. Cardiac cachexia. Br Med J 1991;302:301-2.
31. Rosenthal A. Nutritional considerations in the treatment of children with congenital heart disease. In: Suskind RM, Levinter-Suskind L (eds). Textbook of Pediatric Nutrition. New York, NY, USA: Raven Press, 1993, 383-91.
32. McMurray J, Abdullah I, Dargie HJ. Increased concentrations of tumor necrosis factor in 'cachectic' patients with severe chronic heart failure. Br Heart J 1991;66:356-8.
33. Nagaya N, Uematsu M, Kojima M. Elevated circulating level of ghrelin in cachexia associated with chronic heart failure: relationships between ghrelin and anabolic/catabolic factors. Circulation 2001;104:2034-8.