Molecular dissection of the prototype foamy virus (pfv) RNA 5'-utr identifies essential elements of a ribosomal shunt

Nucleic Acids Research

Volumn 37, Issue 17, 2009, Pages 5838-5847

  Schepetilnikov, Mikhail ^a   Schott, Gregory ^a   Katsarou, Konstantina ^a   Thiébeauld, Odon ^a   Keller, Mario ^a   Ryabova, LLyubov A ^a  

^a UNIVERSITÉ DE STRASBOURG   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CHLORAMPHENICOL ACETYLTRANSFERASE; GAG PROTEIN; GENOMIC RNA; SHORT HAIRPIN RNA;

5' UNTRANSLATED REGION; ARTICLE; CAULIFLOWER MOSAIC VIRUS; CODON; CONTROLLED STUDY; DOWN REGULATION; DOWNSTREAM PROCESSING; GENE INSERTION; NONHUMAN; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; PRIORITY JOURNAL; PROTEIN EXPRESSION; REPORTER GENE; RNA SPLICING; SPUMA VIRUS; STRUCTURAL GENOMICS; TRANSLATION INITIATION;

CAULIFLOWER MOSAIC VIRUS; HUMAN SPUMARETROVIRUS; MAMMALIA; PRIMATES;

EID: 73049096732     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkp609     Document Type: Article

References (38)

1. Kozak, M. (1999) Initiation of translation in prokaryotes and eukaryotes. Gene, 234, 187-208.
2. Pestova, T., Lorsch, J.R. and Hellen, C.U.T. (2007) The mechanism of translation initiation in eukaryotes. In Mathews, M.B., Sonenberg, N. and Hershey, J.W.B (eds), Translational Control in Biology and Medicine. Cold Spring Harbor, NY, pp. 87-128.
3. Jackson, R. (2005) Alternative mechanisms of initiating translation of mammalian mRNAs. Biochem. Soc. Trans., 33, 1231-1241.
4. Balvay, L., Lopez, L.M., Sargueil, B., Darlix, J.L. and Ohlmann, T. (2007) Translational control of retroviruses. Nat. Rev. Microbiol., 5, 128-140.
5. Ryabova, L.A., Pooggin, M.M. and Hohn, T. (2006) Translation reinitiation and leaky scanning in plant viruses. Virus Res., 119, 52-62.
6. Yueh, A. and Schneider, R.J. (2000) Translation by ribosome shunting on adenovirus and hsp70 mRNAs facilitated by complementarity to 18S rRNA. Genes Dev., 14, 414-421.
7. Xi, Q., Cuesta, R. and Schneider, R.J. (2004) Tethering of eIF4G to adenoviral mRNAs by viral 100k protein drives ribosome shunting. Genes Dev., 18, 1997-2009.
8. de Breyne, S., Simonet, V., Pelet, T. and Curran, J. (2003) Identification of a cis-acting element required for shunt-mediated translational initiation of the Sendai virus Y proteins. Nucleic Acids Res., 31, 608-618.
9. Remm, M., Remm, A. and Ustav, M. (1999) Human papillomavirus type 18 E1 protein is translated from polycistronic mRNA by a discontinuous scanning mechanism. J. Virol., 73, 3062-3070.
10. Sen, N., Cao, F. and Tavis, J.E. (2004) Translation of duck hepatitis B virus reverse transcriptase by ribosomal shunting. J. Virol., 78, 11751-11757.
11. Sherrill, K.W. and Lloyd, R.E. (2008) Translation of cIAP2 mRNA is mediated exclusively by a stress-modulated ribosome shunt. Mol. Cell Biol., 28, 2011-2022.
12. Fütterer, J., Kiss-László, Z. and Hohn, T. (1993) Nonlinear ribosome migration on cauliflower mosaic virus 35S RNA. Cell, 73, 789-802.
13. Fütterer, J., Potrykus, I., Bao, Y., Li, L., Burns, T.M., Hull, R. and Hohn, T. (1996) Position-dependent ATT initiation during plant pararetrovirus rice tungro bacilliform virus translation. J. Virol., 70, 2999-3010.
14. Dominguez, D.I., Ryabova, L.A., Pooggin, M.M., Schmidt-Puchta, W., Fütterer, J. and Hohn, T. (1998) Ribosome shunting in cauliflower mosaic virus. Identification of an essential and sufficient structural element. J. Biol. Chem., 273, 3669-3678.
15. Pooggin, M.M., Hohn, T. and Fütterer, J. (2000) Role of a short open reading frame in ribosome shunt on the cauliflower mosaic virus RNA leader. J. Biol. Chem., 275, 17288-17296.
16. Ryabova, L.A. and Hohn, T. (2000) Ribosome shunting in the cauliflower mosaic virus 35S RNA leader is a special case of reinitiation of translation functioning in plant and animal systems. Genes Dev., 14, 817-829.
17. Murray, S.M. and Linial, M.L. (2006) Foamy virus infection in primates. J. Med. Primatol., 35, 225-235.
18. Rethwilm, A. (2007) Foamy virus vectors: an awaited alternative to gammaretro-and lentiviral vectors. Curr. Gene Ther., 7, 261-271.
19. Yu, S.F., Sullivan, M.D. and Linial, M.L. (1999) Evidence that the human foamy virus genome is DNA. J. Virol., 73, 1565-1572.
20. Roy, J., Rudolph, W., Juretzek, T., Gärtner, K., Bock, M., Herchenröder, O., Lindemann, D., Heinkelein, M. and Rethwilm, A. (2003) Feline foamy virus genome and replication strategy. J. Virol., 77, 11324-11331.
21. Moebes, A., Enssle, J., Bieniasz, P.D., Heinkelein, M., Lindemann, D., Bock, M., McClure, M.O. and Rethwilm, A. (1997) Human foamy virus reverse transcription that occurs late in the viral replication cycle. J. Virol., 71, 7305-7311.
22. Löchelt, M., Flügel, R.M. and Aboud, M. (1994) The human foamy virus internal promoter directs the expression of the functional Bel 1 transactivator and Bet protein early after infection. J. Virol., 68, 638-645.
23. Muranyi, W. and Flügel, R.M. (1991) Analysis of splicing patterns of human spumavirus by polymerase chain reaction reveals complex RNA structures. J. Virol., 65, 727-735.
24. Park, J. and Mergia, A. (2000) Mutational analysis of the 5' leader region of simian foamy virus type 1. Virology, 274, 203-212.
25. Green, S., Issemann, I. and Sheer, E. (1988) A versatile in vivo and in vitro eukaryotic expression vector for protein engineering. Nucleic Acids Res., 16, 369.
26. Schmidt, M., Herchenröder, O., Heeney, J. and Rethwilm, A. (1997) Long terminal repeat U3 length polymorphism of human foamy virus. Virology, 230, 167-178.
27. Fütterer, J., Gordon, K., Sanfaçon, H., Bonneville, J.M. and Hohn, T. (1990) Positive and negative control of translation by the leader sequence of cauliflower mosaic virus pregenomic 35S RNA. EMBO J., 9, 1697-1707.
28. Schmidt-Puchta, W., Dominguez, D., Lewetag, D. and Hohn, T. (1997) Plant ribosome shunting in vitro. Nucleic Acids Res., 25, 2854-2860.
29. Kozak, M. (1986) Bifunctional messenger RNAs in eukaryotes. Cell, 47, 481-483.
30. Raney, A., Law, G.L., Mize, G.J. and Morris, D.R. (2002) Regulated translation termination at the upstream open reading frame in s-adenosylmethionine decarboxylase mRNA. J. Biol. Chem., 277, 5988-5994.
31. Mize, G.J., Ruan, H., Low, J.J. and Morris, D.R. (1998) The inhibitory upstream open reading frame from mammalian S-adenosylmethionine decarboxylase mRNA has a strict sequence specificity in critical positions. J. Biol. Chem., 273, 32500-32505.
32. Ryabova, L.A., Pooggin, M.M., Dominguez, D.I. and Hohn, T. (2000) Continuous and discontinuous ribosome scanning on the cauliflower mosaic virus 35 S RNA leader is controlled by short open reading frames. J. Biol. Chem., 275, 37278-37284.
33. Pöyry, T.A., Kaminski, A. and Jackson, R.J. (2004) What determines whether mammalian ribosomes resume scanning after translation of a short upstream open reading frame? Genes Dev., 18, 62-75
34. Paraskeva, E., Gray, N.K., Schlager, B., Wehr, K. and Hentze, M.W. (1999) Ribosomal pausing and scanning arrest as mechanisms of translation regulation from cap-distal iron-responsive elements. Mol. Cell Biol., 19, 807-816.
35. Linial, M.L. (1999) Foamy viruses are unconventional retroviruses. J. Virol., 73, 1747-1755.
36. Russell, R.A., Zeng, Y., Erlwein, O., Cullen, B.R. and McClure, M.O. (2001) The R region found in the human foamy virus long terminal repeat is critical for both Gag and Pol protein expression. J. Virol., 75, 6817-6824.
37. Wiktorowicz, T., Peters, K., Armbruster, N., Steinert, A.F. and Rethwilm, A. (2009) Generation of an improved foamy virus vector by dissection of cis-acting sequences. J. Gen. Virol., 90, 481-487.
38. Guerra-Peraza, O., de Tapia, M., Hohn, T. and Hemmings-Mieszczak, M. (2000) Interaction of the cauliflower mosaic virus coat protein with the pregenomic RNA leader. J. Virol., 74, 2067 2072.