Comorbidity between epilepsy and depression: Role of hippocampal interleukin-1β

Neurobiology of Disease

Volumn 37, Issue 2, 2010, Pages 461-467

  Mazarati, Andrey M ^a   Pineda, Eduardo ^a   Shin, Don ^a   Tio, Delia ^a   Taylor, Anna N ^a   Sankar, Raman ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Brain inflammation; Comorbidity; Depression; Hippocampus; Interleukin 1 ; Temporal lobe epilepsy

Indexed keywords

DIAZEPAM; INTERLEUKIN 1 RECEPTOR; INTERLEUKIN 1BETA; PHENYTOIN; PILOCARPINE; RECOMBINANT INTERLEUKIN 1 RECEPTOR BLOCKING AGENT;

ANHEDONIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; COMORBIDITY; CONTROLLED STUDY; DEPRESSION; DRUG MECHANISM; EPILEPTIC STATE; HIPPOCAMPUS; HOPELESSNESS; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR BLOCKING; SEIZURE; SEROTONINERGIC TRANSMISSION; SIGNAL TRANSDUCTION; TEMPORAL LOBE EPILEPSY; WISTAR RAT;

ANIMALS; ANTIDEPRESSIVE AGENTS; BEHAVIOR, ANIMAL; COMORBIDITY; CONVULSANTS; DEPRESSIVE DISORDER; DISEASE MODELS, ANIMAL; EPILEPSY; HIPPOCAMPUS; HYPOTHALAMO-HYPOPHYSEAL SYSTEM; INTERLEUKIN 1 RECEPTOR ANTAGONIST PROTEIN; INTERLEUKIN-1BETA; MALE; NEURAL PATHWAYS; PILOCARPINE; PITUITARY-ADRENAL SYSTEM; RAPHE NUCLEI; RATS; RATS, WISTAR; RECEPTORS, INTERLEUKIN-1; STATUS EPILEPTICUS;

EID: 73049083333     PISSN: 09699961     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nbd.2009.11.001     Document Type: Article

References (57)

1. Aghajanian G.K., Sprouse J.S., Sheldon P., and Rasmussen K. Electrophysiology of the central serotonin system: receptor subtypes and transducer mechanisms. Ann. N. Y. Acad. Sci. 600 (1990) 93-103 discussion 103
2. Barbui C., Hotopf M., and Garattini S. Fluoxetine dose and outcome in antidepressant drug trials. Eur. J. Clin. Pharmacol. 58 (2002) 379-386
3. Bartfai T., Sanchez-Alavez M., Andell-Jonsson S., Schultzberg M., Vezzani A., Danielsson E., and Conti B. Interleukin-1 system in CNS stress: seizures, fever, and neurotrauma. Ann. N.Y. Acad. Sci. 1113 (2007) 173-177
4. Bellido I., Hansson A.C., Gomez-Luque A.J., Andbjer B., Agnati L.F., and Fuxe K. Corticosterone strongly increases the affinity of dorsal raphe 5-HT1A receptors. Neuroreport 15 (2004) 1457-1459
5. Boldrini M., Underwood M.D., Mann J.J., and Arango V. Serotonin-1A autoreceptor binding in the dorsal raphe nucleus of depressed suicides. J. Psychiatr. Res. 42 (2008) 433-442
6. Bunin M.A., and Wightman R.M. Quantitative evaluation of 5-hydroxytryptamine (serotonin) neuronal release and uptake: an investigation of extrasynaptic transmission. J. Neurosci. 18 (1998) 4854-4860
7. Capuron L., and Dantzer R. Cytokines and depression: the need for a new paradigm. Brain Behav. Immun. 17 Suppl. 1 (2003) S119-S124
8. Chaput Y., de Montigny C., and Blier P. Effects of a selective 5-HT reuptake blocker, citalopram, on the sensitivity of 5-HT autoreceptors: electrophysiological studies in the rat brain. Naunyn. Schmiedebergs Arch. Pharmacol. 333 (1986) 342-348
9. De Kloet E.R., and Reul J.M. Feedback action and tonic influence of corticosteroids on brain function: a concept arising from the heterogeneity of brain receptor systems. Psychoneuroendocrinology 12 (1987) 83-105
10. Dunn A.J., and Swiergiel A.H. Effects of interleukin-1 and endotoxin in the forced swim and tail suspension tests in mice. Pharmacol. Biochem. Behav. 81 (2005) 688-693
11. Dunn A.J., Swiergiel A.H., and de Beaurepaire R. Cytokines as mediators of depression: what can we learn from animal studies?. Neurosci. Biobehav. Rev. 29 (2005) 891-909
12. Galic M.A., Riazi K., Heida J.G., Mouihate A., Fournier N.M., Spencer S.J., Kalynchuk L.E., Teskey G.C., and Pittman Q.J. Postnatal inflammation increases seizure susceptibility in adult rats. J. Neurosci. 28 (2008) 6904-6913
13. Gilliam F.G., Maton B.M., Martin R.C., Sawrie S.M., Faught R.E., Hugg J.W., Viikinsalo M., and Kuzniecky R.I. Hippocampal 1H-MRSI correlates with severity of depression symptoms in temporal lobe epilepsy. Neurology 68 (2007) 364-368
14. Jackson B.P., Dietz S.M., and Wightman R.M. Fast-scan cyclic voltammetry of 5-hydroxytryptamine. Anal. Chem. 67 (1995) 1115-1120
15. Johnson S.A., Fournier N.M., and Kalynchuk L.E. Effect of different doses of corticosterone on depression-like behavior and HPA axis responses to a novel stressor. Behav. Brain Res. 168 (2006) 280-288
16. Kalliolias G.D., and Liossis S.N. The future of the IL-1 receptor antagonist anakinra: from rheumatoid arthritis to adult-onset Still's disease and systemic-onset juvenile idiopathic arthritis. Expert. Opin. Investig. Drugs 17 (2008) 349-359
17. Kanner A.M. Depression in epilepsy: prevalence, clinical semiology, pathogenic mechanisms, and treatment. Biol. Psychiatry 54 (2003) 388-398
18. Knedla A., Riepl B., Lefevre S., Kistella S., Grifka J., Straub R.H., Gay S., Scholmerich J., Muller-Ladner U., and Neumann E. The therapeutic use of osmotic minipumps in the severe combined immunodeficiency (SCID) mouse model for rheumatoid arthritis. Ann. Rheum. Dis. 68 (2009) 124-129
19. Kondziella D., Alvestad S., Vaaler A., and Sonnewald U. Which clinical and experimental data link temporal lobe epilepsy with depression?. J. Neurochem. 103 (2007) 2136-2152
20. Konsman J.P., Veeneman J., Combe C., Poole S., Luheshi G.N., and Dantzer R. Central nervous action of interleukin-1 mediates activation of limbic structures and behavioural depression in response to peripheral administration of bacterial lipopolysaccharide. Eur. J. Neurosci. 28 (2008) 2499-2510
21. Le Poul E., Laaris N., Doucet E., Laporte A.M., Hamon M., and Lanfumey L. Early desensitization of somato-dendritic 5-HT1A autoreceptors in rats treated with fluoxetine or paroxetine. Naunyn. Schmiedebergs Arch. Pharmacol. 352 (1995) 141-148
22. Leonard B.E. HPA and immune axes in stress: involvement of the serotonergic system. Neuroimmunomodulation 13 (2006) 268-276
23. Lothe A., Didelot A., Hammers A., Costes N., Saoud M., Gilliam F., and Ryvlin P. Comorbidity between temporal lobe epilepsy and depression: a [18F]MPPF PET study. Brain 131 (2008) 2765-2782
24. Man M.S., Young A.H., and McAllister-Williams R.H. Corticosterone modulation of somatodendritic 5-HT1A receptor function in mice. J. Psychopharmacol. 16 (2002) 245-252
25. Mann J.J., Arango V., Marzuk P.M., Theccanat S., and Reis D.J. Evidence for the 5-HT hypothesis of suicide. A review of post-mortem studies. Br. J. Psychiatry Suppl. (1989) 7-14
26. Marchi N., Fan Q., Ghosh C., Fazio V., Bertolini F., Betto G., Batra A., Carlton E., Najm I., Granata T., and Janigro D. Antagonism of peripheral inflammation reduces the severity of status epilepticus. Neurobiol. Dis. 33 (2009) 171-181
27. Marcon J., Gagliardi B., Balosso S., Maroso M., Noe F., Morin M., Lerner-Natoli M., Vezzani A., and Ravizza T. Age-dependent vascular changes induced by status epilepticus in rat forebrain: implications for epileptogenesis. Neurobiol. Dis. 34 (2009) 121-132
28. Mazarati A., Siddarth P., Baldwin R.A., Shin D., Caplan R., and Sankar R. Depression after status epilepticus: behavioural and biochemical deficits and effects of fluoxetine. Brain 131 (2008) 2071-2083
29. Mazarati A.M., Shin D., Kwon Y.S., Bragin A., Pineda E., Tio D., Taylor A.N., and Sankar R. Elevated plasma corticosterone level and depressive behavior in experimental temporal lobe epilepsy. Neurobiol. Dis. 34 (2009) 457-461
30. Mazarati A., Shin D., Bragin A., Tio D., Taylor A., and Sankar R. Hyperactivity of hypothalamo-pituitary-adrenocortical axis in a rat model of temporal lobe epilepsy: a mechanism of comorbidity between epilepsy and depression. Epilepsia 50 Suppl. 10 (2009) 68
31. Melik Parsadaniantz S., Dauge V., Roques B.P., and Kerdelhue B. Acute intrahippocampal injection of human interleukin-1beta stimulates the anterior pituitary POMC transcription and increases plasma levels of ACTH and corticosterone in the male rat. Neuroendocrinology 69 (1999) 77-87
32. Murphy D.L., Campbell L., and Costa J.L. The brain serotonergic system in the affective disorders. In: Lipton M.A., DiMascio A., and Killam K.F. (Eds). Psychopharmacology: A Generation of Progress (1978), Raven Press, New York 1235-1247
33. O'Connor J.C., Lawson M.A., Andre C., Moreau M., Lestage J., Castanon N., Kelley K.W., and Dantzer R. Lipopolysaccharide-induced depressive-like behavior is mediated by indoleamine 2,3-dioxygenase activation in mice. Mol. Psychiatry 14 (2009) 511-522
34. Pariante C.M., and Miller A.H. Glucocorticoid receptors in major depression: relevance to pathophysiology and treatment. Biol. Psychiatry 49 (2001) 391-404
35. Pohorecky L.A., Baumann M.H., and Benjamin D. Effects of chronic social stress on neuroendocrine responsiveness to challenge with ethanol, dexamethasone and corticotropin-releasing hormone. Neuroendocrinology 80 (2004) 332-342
36. Pucilowski O., and Overstreet D.H. Effect of chronic antidepressant treatment on responses to apomorphine in selectively bred rat strains. Brain Res. Bull. 32 (1993) 471-475
37. Pucilowski O., Overstreet D.H., Rezvani A.H., and Janowsky D.S. Chronic mild stress-induced anhedonia: greater effect in a genetic rat model of depression. Physiol. Behav. 54 (1993) 1215-1220
38. Ravizza T., Gagliardi B., Noe F., Boer K., Aronica E., and Vezzani A. Innate and adaptive immunity during epileptogenesis and spontaneous seizures: evidence from experimental models and human temporal lobe epilepsy. Neurobiol. Dis. 29 (2008) 142-160
39. Relton J.K., Martin D., Thompson R.C., and Russell D.A. Peripheral administration of interleukin-1 receptor antagonist inhibits brain damage after focal cerebral ischemia in the rat. Exp. Neurol. 138 (1996) 206-213
40. Riad M., Garcia S., Watkins K.C., Jodoin N., Doucet E., Langlois X., el Mestikawy S., Hamon M., and Descarries L. Somatodendritic localization of 5-HT1A and preterminal axonal localization of 5-HT1B serotonin receptors in adult rat brain. J. Comp. Neurol. 417 (2000) 181-194
41. Riazi K., Galic M.A., Kuzmiski J.B., Ho W., Sharkey K.A., and Pittman Q.J. Microglial activation and TNFalpha production mediate altered CNS excitability following peripheral inflammation. Proc. Natl. Acad. Sci. U. S. A. 105 (2008) 17151-17156
42. Rigau V., Morin M., Rousset M.C., de Bock F., Lebrun A., Coubes P., Picot M.C., Baldy-Moulinier M., Bockaert J., Crespel A., and Lerner-Natoli M. Angiogenesis is associated with blood-brain barrier permeability in temporal lobe epilepsy. Brain 130 (2007) 1942-1956
43. Sandberg J.O., Eizirik D.L., Sandler S., Tracey D.E., and Andersson A. Treatment with an interleukin-1 receptor antagonist protein prolongs mouse islet allograft survival. Diabetes 42 (1993) 1845-1851
44. Sanderson K.L., Raghupathi R., Saatman K.E., Martin D., Miller G., and McIntosh T.K. Interleukin-1 receptor antagonist attenuates regional neuronal cell death and cognitive dysfunction after experimental brain injury. J. Cereb. Blood Flow. Metab. 19 (1999) 1118-1125
45. Steimer T., Python A., Schulz P.E., and Aubry J.M. Plasma corticosterone, dexamethasone (DEX) suppression and DEX/CRH tests in a rat model of genetic vulnerability to depression. Psychoneuroendocrinology 32 (2007) 575-579
46. Stockmeier C.A., Shapiro L.A., Dilley G.E., Kolli T.N., Friedman L., and Rajkowska G. Increase in serotonin-1A autoreceptors in the midbrain of suicide victims with major depression-postmortem evidence for decreased serotonin activity. J. Neurosci. 18 (1998) 7394-7401
47. Swaab D.F., Bao A.M., and Lucassen P.J. The stress system in the human brain in depression and neurodegeneration. Ageing. Res. Rev. 4 (2005) 141-194
48. van den Biggelaar A.H., Gussekloo J., de Craen A.J., Frolich M., Stek M.L., van der Mast R.C., and Westendorp R.G. Inflammation and interleukin-1 signaling network contribute to depressive symptoms but not cognitive decline in old age. Exp. Gerontol. 42 (2007) 693-701
49. Vezzani A., Balosso S., and Ravizza T. The role of cytokines in the pathophysiology of epilepsy. Brain. Behav. Immun. 22 (2008) 797-803
50. Vezzani A., Conti M., De Luigi A., Ravizza T., Moneta D., Marchesi F., and De Simoni M.G. Interleukin-1beta immunoreactivity and microglia are enhanced in the rat hippocampus by focal kainate application: functional evidence for enhancement of electrographic seizures. J. Neurosci. 19 (1999) 5054-5065
51. Vezzani A., and Granata T. Brain inflammation in epilepsy: experimental and clinical evidence. Epilepsia 46 (2005) 1724-1743
52. Vezzani A., Moneta D., Conti M., Richichi C., Ravizza T., De Luigi A., De Simoni M.G., Sperk G., Andell-Jonsson S., Lundkvist J., Iverfeldt K., and Bartfai T. Powerful anticonvulsant action of IL-1 receptor antagonist on intracerebral injection and astrocytic overexpression in mice. Proc. Natl. Acad. Sci. U. S. A. 97 (2000) 11534-11539
53. Vezzani A., Moneta D., Richichi C., Aliprandi M., Burrows S.J., Ravizza T., Perego C., and De Simoni M.G. Functional role of inflammatory cytokines and antiinflammatory molecules in seizures and epileptogenesis. Epilepsia 43 Suppl. 5 (2002) 30-35
54. Watson S., Gallagher P., Smith M.S., Ferrier I.N., and Young A.H. The dex/CRH test-is it better than the DST?. Psychoneuroendocrinology 31 (2006) 889-894
55. Wrona M.Z., and Dryhurst G. Oxidation chemistry of 5-hydroxytryptamine. 1. Mechanism and products formed at micromolar concentrations. J. Org. Chem. 52 (1987) 2817-2825
56. Yirmiya R. Endotoxin produces a depressive-like episode in rats. Brain Res. 711 (1996) 163-174
57. Zobel A., Wellmer J., Schulze-Rauschenbach S., Pfeiffer U., Schnell S., Elger C., and Maier W. Impairment of inhibitory control of the hypothalamic pituitary adrenocortical system in epilepsy. Eur. Arch. Psychiatry Clin. Neurosci. 254 (2004) 303-311