메뉴 건너뛰기




Volumn 11, Issue 24, 2009, Pages 5638-5641

An aldol approach to the total synthesis of pamamycin 621 A

Author keywords

[No Author keywords available]

Indexed keywords

MACROLIDE; PAMAMYCIN 621 A;

EID: 72849116100     PISSN: 15237060     EISSN: None     Source Type: Journal    
DOI: 10.1021/ol902290v     Document Type: Article
Times cited : (20)

References (58)
  • 41
    • 72849114700 scopus 로고    scopus 로고
    • Without the TMS protection, the two C-10 epimers (19a and 19b without the TMS group on C-8 OH) were inseparable on silica gel.
    • Without the TMS protection, the two C-10 epimers (19a and 19b without the TMS group on C-8 OH) were inseparable on silica gel.
  • 42
    • 72849111020 scopus 로고    scopus 로고
    • Essentially no reaction occurred if using Zn or Mg salt of 7. The asymmetric protocol of Carreira see
    • (a) Essentially no reaction occurred if using Zn or Mg salt of 7. The asymmetric protocol of Carreira (see,
  • 44
    • 72849140615 scopus 로고    scopus 로고
    • The relative configurations of 19a/b were established through NOEs of their C-8 OH/C-10 OH acetonides.
    • (c) The relative configurations of 19a/b were established through NOEs of their C-8 OH/C-10 OH acetonides.
  • 45
    • 0001408299 scopus 로고
    • For a literature precedent using a primary amine for such a purpose, see
    • For a literature precedent using a primary amine for such a purpose, see: Czech, B. P.; Barsch, R. A. J. Org. Chem. 1984, 49, 4076-4078.
    • (1984) J. Org. Chem. , vol.49 , pp. 4076-4078
    • Czech, B.P.1    Barsch, R.A.2
  • 46
    • 72849122705 scopus 로고    scopus 로고
    • We are not aware of similar precedents in the literature; such an etherification usually occurs only under basic conditions.
    • We are not aware of similar precedents in the literature; such an etherification usually occurs only under basic conditions.
  • 47
    • 72849106746 scopus 로고    scopus 로고
    • We are not aware of any literature precedents.
    • We are not aware of any literature precedents.
  • 53
    • 72849127289 scopus 로고    scopus 로고
    • We are not aware of any precedents of application of this protocol to complex enals with an eliminable ethereal group at the allylic position.
    • We are not aware of any precedents of application of this protocol to complex enals with an eliminable ethereal group at the allylic position.
  • 55
    • 72849109802 scopus 로고    scopus 로고
    • In other routes involving similar coupling, the C-8 OH was all masked as either a TBS ether or an acetate (ref 2a,g,f).
    • In other routes involving similar coupling, the C-8 OH was all masked as either a TBS ether or an acetate (ref 2a,g,f).
  • 58
    • 72849134281 scopus 로고    scopus 로고
    • 3
    • 3!


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.