Interleukin-6 -174 G/C promoter polymorphism and nasal polyposis

Rhinology

Volumn 47, Issue 4, 2009, Pages 400-404

  Kosugi, Eduardo Macoto ^a,b   De Camargo Kosugi, Cíntia Meirelles ^a   Weckx, Luc Louis Maurice ^a   Guerreiro da Silva, Ismael Dale Cotrim ^a   Gregório, Luiz Carlos ^a  

^a FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

^b João de Oliveira Torres ^*  (Brazil)

Author keywords

Genetic polymorphism; Interleukin 6; Nasal polyps; Restriction fragment length polymorphism; Single nucleotide polymorphism

Indexed keywords

EID: 72849112405     PISSN: 03000729     EISSN: None     Source Type: Journal    
DOI: 10.4193/rhin08.226     Document Type: Article

References (19)

1. Pawankar R. Nasal polyposis: an update. Cur Opin Allergy Clin Immunol 2003; 3: 1-6.
2. Fokkens W, Lund V, Mullol J, European Position Paper on Rhinosinusitis and Nasal Polyps group. European position paper on rhinosinusitis and nasal polyps 2007. Rhinol Suppl 2007; 20: 1136.
3. 3. Rinia AB, Kostamo K, Ebbens FA, van Drunen CM, Fokkens WJ. Nasal polyposis: a cellular-based approach to answering questions. Allergy 2007; 62: 348-358. (Pubitemid 46398804)
4. Watelet JB, Van Zele T, Gjomarkaj M, et al. Tissue remodeling in upper airways: where is the link with lower airway remodeling? Allergy 2006; 61: 1249-1258.
5. Figueiredo CR, Silva IDGC, Weckx LLM. Inflamatory Genes in Nasal Polyposis. Curr Opin Otolaryngol Head Neck Surg 2008; 16: 18-21.
6. Danielsen A, Tynning T, Brokstad KA, Olofsson J, Davidson A. Interleukin 5, IL6, IL12, IFN-γ, RANTES and Fractalkine in human nasal polyps, turbinate mucosa and serum. Eur Arch Otorhinolaryngol 2006; 263: 282-289.
7. 7. Haruna S, Nakanishi M, Otori N, Moriyama H. Histopathological features of nasal polyps with asthma association: an immunohistochemical study. Am J Rhinol 2004; 18: 165-172. (Pubitemid 39029214)
8. Nogueira de Souza NC, Brenna SMF, Campos F, Syrjänen KJ, Baracat EC e Silva IDCG. Interleukin-6 polymorphisms and the risk of cervical cancer. Int J Gynecol Cancer 2006; 16: 1278-1282.
9. Terry CF, Loukaci V, Green FR. Cooperative Influence of Genetic Polymorphisms on Interleukin-6 Transcriptional Regulation. J Biol Chem 2000; 275(24): 18138-18144.
10. Payne SC, Han JK, Huyett P, Negri J, Kropf EZ, Borish L, et al. Microarray analysis of distinct gene transcription profiles in noneosinophilic chronic sinusitis with nasal polyps. Am J Rhinol 2008; 22: 568-581.
11. Park SK, Jang WH, Yang YI. Expression of pro-angiogenic cytokines and their inhibition by dexamethasone in na ex vivo model of nasal polyps. Biochem Biophys Res Commun. 2009; 379: 255-260.
12. Xu G, Xia JH, Zhou H, Yu CZ, Zhang Y, Zuo KJ, et al. Interleukin-6 is essential for Saphylococcal exotoxin B - induced T regulatory cell insufficiency in nasal polyps. Clin Exp Allergy. 2009; 39: 829-837.
13. Fishman D, Faulds G, Jeffery R, et al. The Effect of Novel Polymorphisms in the Interleukin-6 Gene on IL-6 Transcription and Plasma IL-6 Levels, and an Association with Systemic-Onset Juvenile Chronic Arthritis. J Clin Invest 1998; 102(7): 1369-1376.
14. Naugler WE, Karin M. The wolf in sheep's clothing: the role of interleukin-6 in immunity, inflammation and cancer. Trends Mol Med 2008; 14 (3): 109-119.
15. Hurst SM, Wilkinson TS, McLoughlin RM, et al. IL-6 and its soluble receptor orchestrate a temporal switch in the patter of leukocyte recruitment seen during acute inflammation. Immunity 2001; 14 (6): 705-714.
16. Iwakura Y, Ishigame H. The IL-23/IL-17 axis in inflammation. J Clin Invest 2006; 116: 1218-1222.
17. Bradley DT, Kountakis SE. Role of Interleukins and Transforming Growth Factor- in Chronic Rhinosinusitis and Nasal Polyposis. Laryngoscope 2005; 115: 684-686.
18. 18. Karjalainen J, Joke-Erkkilä VP, Huikkonen J, et al. The ILIA genotype is associated with nasal polyposis in asthmatic adults. Allergy 2003; 58: 393-396. (Pubitemid 36605727)
19. Park SK, Heo KW, Jung H, Yea SS e Yang YII. Expression of ciclooxygenase-2 and 5-lipoxygenase in nasal polyps associated with interleukin-4 promoter polymorphism -590. Otolaryngol Head Neck Surg 2006; 135: 928-932.