I. the little explored efficacy of magnetic fields in cancer treatment and postulation of the mechanism of action

Electromagnetic Biology and Medicine

Volumn 28, Issue 3, 2009, Pages 275-282

  Elson, Edward ^a  

^a UNIVERSITY OF MARYLAND   (United States)

Author keywords

Apoptosis in tumors; Biological effects of magnetic fields; Cancer treatment; DNA charge transfer; DNA conductivity; Faraday forces; Lorentz forces; Magnetic fields; Torsional modes in DNA

Indexed keywords

APOPTOSIS; APOPTOSIS IN TUMORS; BIOLOGICAL EFFECTS; BIOLOGICAL EFFECTS OF MAGNETIC FIELDS; CANCER TREATMENT; DNA CHARGE TRANSFER; DNA CONDUCTIVITY; TORSIONAL MODES;

ANIMAL CELL CULTURE; ANIMALS; BIOLOGICAL RADIATION EFFECTS; CELL CULTURE; CELL DEATH; CHARGE TRANSFER; ELECTROMAGNETIC FIELD MEASUREMENT; ELECTROMAGNETIC FIELDS; GENES; ION EXCHANGE; LORENTZ FORCE; MAGNETIC FIELD EFFECTS; MAGNETIC MATERIALS; MAGNETISM; MASS TRANSFER; NUCLEIC ACIDS; ONCOLOGY; TUMORS;

DNA;

ANIMALIA;

DNA;

ANIMAL; CHEMISTRY; GENETICS; HUMAN; MAGNETISM; MAGNETOTHERAPY; NEOPLASM; PATHOLOGY; REVIEW; TIME;

ANIMALS; DNA; HUMANS; MAGNETIC FIELD THERAPY; MAGNETICS; NEOPLASMS; TIME FACTORS;

EID: 72749127105     PISSN: 15368378     EISSN: 15368386     Source Type: Journal    
DOI: 10.3109/15368370903114271     Document Type: Article

References (26)

1. Benham, C. J. (1992). Energetics of the strand separation transition in superhelical DNA. J. Mol. Biol. 225:835-847.
2. Blank, M., Goodman, R. (2008). A mechanism for stimulation of biosynthesis by electromagnetic fields: Charge transfer in DNA and base pair separation. J. Cell. Physiol. 214:20-26.
3. Cameron, I. L., Sun, L.-Z., Short, N., et al. (2005). Therapeutic electromagnetic field (TEMF) and gamma irradiation on human breast cancer xenograft growth, angiogenesis and metastasis. Cancer Cell Int. 5:23-45.
4. de Seze, R., Tuffet, S., Moreau, J.-M., Veyret, B. (2000). Effects of 100mT time varying magnetic fields on the growth of tumors in mice. Bioelectromagnetics 21:107-111.
5. Devi Prasad, K. V., Prohofsky, E. W. (1984). Low-frequency lattice mode predictions in A-DNA compared to experimental observations and significance for A-to-B conformation change. Biopolymers 23:1795.
6. Funk, R. H., Monsees, T. K. (2006). Effects of electromagnetic fields on cells: Physiological and therapeutic approaches and molecular mechanisms of interaction A review. Cells Tissues Organs 182:59-78.
7. Goodman, R., Bassett, C. A. L., Henderson, A. (1983). Pulsing electromagnetic fields induce cellular transcription. Science 220:1283-1285.
8. Hallett, M. (2007). Transcranial magnetic stimulation: A primer. Neuron 55:187-199.
9. Hanahan, D., Weinberg, R. A. (2000). The hallmarks of cancer. Cell 100:57-70.
10. Ivanov, V., Zeng, T., Zocchi, G. (2004). Statistical mechanics of base stacking and pairing in DNA melting. Phys. Rev. E Statist. Nonlin. Soft Matter Phys. 70:051907.
11. Kohli, M., Mei, W. N., Prohofsky, E. W., Van Zandi, L. L. (1981). Calculated microwave absorption of double helical B-Conformation poly(dG).poly(dC). Biopolymers 20:853-864.
12. Kwee, S., Raskmark, R., Velizarov, S. (2001). Changes in cellular proteins due to environmental non-ionizing Heat-shock proteins. Electro Magnetobiol. 20:141-152.
13. Lai, H., Singh, N. P. (2004). Magnetic field induced DNA strand breaks in brain cells of the rat. Environ. Health Perspect. 112:687-694.
14. Levin, M., Ernst, S. G. (1995). Applied AC and DC magnetic fields cause alterations in the mitotic cycle of early sea urchin embryos. Bioelectromagnetics 16:231-240.
15. Liang, Y., Hannan, C. J., Chang, B. K., Schoenlein, P. V. (1997). Enhanced potency of Daunorubicin against multidrug resistant subline KB-Chr-8-5-11 by a pulsed magnetic field. Anticancer Res. 17:2083-2088.
16. Liboff, A. R., Williams, Jr., T., Strong, D. M., Wistar, Jr., R. (1984). Time-varying magnetic fields: Effect on DNA synthesis. Science 223:818-820.
17. Nossol, B., Buse, G., Silny, J. (1993). Influence of weak static and 50 Hz magnetic fields on the redox activity of cytochrome-C oxidase. Bioelectromagnetics 14:361-372.
18. Omote, Y., Hosokawa, M., Namieno, T., et al. (1990). Treatment of experimental tumors with a combination of a pulsing magnetic field and an antitumor drug. Japan J. Cancer Res. 81:956-961.
19. Polk, C., Postow, E., Eds. (1996). Handbook of Biological Effects of Electromagnetic Fields (2nd ed.). Boca Raton, FL: CRC Press.
20. -1 mode in DNA. J. Biomol. Struct. Dyn. 10:227-237.
21. Singh, N., Singh, Y. (2003). Statistical mechanics of thermal denaturation of DNA oligomers. Pramana 61:345-352.
22. Tofani, S., Barone, T., Cintorino, M., et al. (2001). Static and ELF magnetic fields induce tumor growth inhibition and apoptosis. Bioelectromagnetics 22:419-428.
23. Urabe, H., Tominaga, Y., Kubota, K. (1983). Experimental evidence of collective vibrations in DNA double helix (Raman spectroscopy). J. Chem. Phys. 78:5937-5939.
24. Volpe, P. (2003). Interactions of zero-frequency and oscillating magnetic fields with biostructures and biosystems. Photochem. Photobiol. Sci. 2:637-648.
25. Williams, C. D., Markov, M. S., Hardman, W. E., Cameron, I. L. (2001). Therapeutic electromagnetic field effects on angiogenesis and tumor growth. Anticancer Res. 21:3887-3891.
26. Zhuang, W., Chen, Y. A., Prohofsky, E. W. (1992). Description of base motion and role of excitations in the melting of poly(dG).poly(dC). J. Biomol. Struct. Dyn. 10:403-414.