Expression profile of the small heat-shock protein alpha-B-crystallin in operated-on non-small-cell lung cancer patients: clinical implication

European Journal of Cardio-thoracic Surgery

Volumn 37, Issue 1, 2010, Pages 44-50

  Cherneva, Radostina ^a   Petrov, Danail ^a   Georgiev, Ognian ^a   Slavova, Yanina ^a   Toncheva, Draga ^a   Stamenova, Maria ^a   Trifonova, Nedka ^a  

^a Department of Internal Medicine ^*  (Bulgaria)

Author keywords

Alpha B crystallin; Biomarker; Molecular substaging; NSCLC; Poor prognosis

Indexed keywords

ALPHA B CRYSTALLIN; SMALL HEAT SHOCK PROTEIN; UNCLASSIFIED DRUG;

ADULT; AGE; AGED; ARTICLE; CANCER STAGING; CANCER SURVIVAL; CARCINOGENESIS; FEMALE; GENDER; HUMAN; IMMUNOHISTOCHEMISTRY; LUNG NON SMALL CELL CANCER; MAJOR CLINICAL STUDY; MALE; METASTASIS; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ADULT; AGED; ALPHA-CRYSTALLIN B CHAIN; CARCINOMA, NON-SMALL-CELL LUNG; CELL NUCLEUS; CYTOPLASM; EPIDEMIOLOGIC METHODS; FEMALE; HUMANS; LUNG NEOPLASMS; MALE; MIDDLE AGED; NEOPLASM PROTEINS; NEOPLASM STAGING; PNEUMONECTOMY; PROGNOSIS; TISSUE ARRAY ANALYSIS; TUMOR MARKERS, BIOLOGICAL;

EID: 72749119478     PISSN: 10107940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejcts.2009.06.038     Document Type: Article

References (23)

1. Moyano J.V., Evans J.R., Chen F., Lu M., Werner M.E., Yehiely F., Diaz L.K., Turbin D., Karaca G., Wiley E., Nielsen T.O., Perou C.M., and Cryns V.L. Alpha-B-crystallin is a novel oncoprotein that predicts poor clinical outcome in breast cancer. J Clin Invest 116 1 (2006) 261-270
2. Pinder S.E., Balsitis M., Ellis I.O., Landon M., Mayer R.J., and Lowe J. The expression of alpha B-crystallin in epithelial tumours: a useful tumour marker?. J Pathol 174 3 (1994) 209-215
3. Wittig R., Nessling M., Will R.D., Mollenhauer J., Salowsky R., Münstermann E., Schick M., Helmbach H., Gschwendt B., Korn B., Kioschis P., Lichter P., Schadendorf D., and Poustka A. Candidate genes for cross-resistance against DNA-damaging drugs. Cancer Res 62 22 (2002) 6698-6705
4. Lin D.I., Barbash O., Kumar K.G., Weber J.D., Harper J.W., Klein-Szanto A.J., Rustgi A., Fuchs S.Y., and Diehl J.A. Phosphorylation-dependent ubiquitination of cyclin D1 by the SCF (FBX4-alphaB crystallin) complex. Mol Cell 24 3 (2006) 355-366
5. Dimberg A., Rylova S., Dieterich L.C., Olsson A.K., Schiller P., Wikner C., Bohman S., Botling J., Lukinius A., Wawrousek E.F., and Claesson-Welsh L. Alpha-B-crystallin promotes tumor angiogenesis by increasing vascular survival during tube morphogenesis. Blood 111 4 (2008) 2015-2023
6. Kamradt M.C., Lu M., Werner M.E., Kwan T., Chen F., Strohecker A., Oshita S., Wilkinson J.C., Yu C., Oliver P.G., Duckett C.S., Buchsbaum D.J., LoBuglio A.F., Jordan V.C., and Cryns V.L. The small heat shock protein alpha B-crystallin is a novel inhibitor of TRAIL-induced apoptosis that suppresses the activation of caspase-3. J Biol Chem 280 12 (2005) 11059-11066
7. Sitterding S.M., Wiseman W.R., Schiller C.L., Luan C., Chen F., Moyano J.V., Watkin W.G., Wiley E.L., Cryns V.L., and Diaz L.K. Alpha-B-crystallin: a novel marker of invasive basal-like and metaplastic breast carcinomas. Ann Diagn Pathol 12 1 (2008) 33-40
8. Hanahan D., and Weinberg R.A. The Hallmarks of cancer. Cell 100 (2000) 57-67
9. Head M.W., Hurwitz L., Kegel K., and Goldman J.E. AlphaB-crystalline regulates intermediate filament organization in situ. NeuroReport 11 (2000) 361-365
10. Narberhaus F. Alpha-crystallin type heat shock proteins: socializing minichaperones in the context of a multichaperone network. Microbiol Mol Biol Rev 66 (2002) 64-93
11. MacRae T.H. Structure and function of small heat shock/alpha crystalline proteins: established concepts and emerging ideas. Cell Mol Life Sci 57 (2000) 899-913
12. Kamradt M.C., Chen F., and Cryns V.L. The small heat shock protein alpha B-crystallin negatively regulates cytochrome c- and caspase-8-dependent activation of caspase-3 by inhibiting its autoproteolytic maturation. J Biol Chem 276 19 (2001) 16059-16063
13. Mao Y.W., Liu J.P., Xiang H., and Li D.W. Human alphaA- and alphaB-crystallins bind to Bax and Bcl-X(S) to sequester their translocation during staurosporine induced apoptosis. Cell Death Differ 11 5 (2004) 512-526
14. Liu S., Li J., Tao Y., and Xiao X. Small heat shock protein alphaB-crystallin binds to p53 to sequester its translocation to mitochondria during hydrogen peroxide-induced apoptosis. Biochem Biophys Res Commun 354 1 (2007) 109-114
15. Gruvberger S., and Parsons R. Is the small heat shock protein alpha-B-crystallin an oncogene?. J Clin Invest 116 (2006) 30-32
16. Chelouche-Lev D., Kluge H.M., Berger A.J., and Rimm D.L. αB-crystallin as a marker of lymph node involvement in breast. Carcinoma Cancer 100 (2004) 2543-2548
17. Ghosh J., Shenoy A., and Clark J. Interactions between important regulatory proteins and human αB crystalline. Biochemistry 46 21 (2007) 6308-6317
18. Klemenz R., Fröhli E., Steiger R., Schäfer R., and Aoyama A. αB crystalline is a small heat shock protein. Proc Natl Acad Sci 88 (1991) 3652-3656
19. Voorter Ch, Wintjes L., Bloemendal H., and Jong W. Relocalization of alpha-B-crystallin by heat shock in ovarian carcinoma cells. FEBS 309 2 (1992) 111-114
20. Adhikari A., Rao S., Rangaraj N., Parniak V., and Rao Ch. Heat stress-induced localization of small heat shock proteins in mouse myoblasts: intranuclear lamin A/C speckles as target for alpha-B crystalline and Hsp25. Exp Cell Res 299 (2004) 393-403
21. IJessel P., Wheelock R., Prescott A., Russel P., and Quinlan R. Nuclear speckle localization of the small heat shock protein alphaB-crystallin and its inhibition by the R120G cardiomyopathy-linked mutation. Exp Cell Res 287 (2003) 249-261
22. Chen J., He Q.Y., Yuen A.P., and Chiu J.F. Proteomics of buccal squamous cell carcinoma: the involvement of multiple pathways in tumorigenesis. Proteomics 4 8 (2004) 2465-2475
23. Chin D., Boyle G., Williams R., Ferguson K., Pandeya N., Pedley J., Campbell C., Theile D., Parsons P., and Coman W. Alpha-B crystalline, a new independent marker for poor prognosis in head and neck cancer. Laryngoscope 115 (2005) 1239-1242