2.6 Å X-ray crystal structure of human p53R2, a p53-inducible ribonucleotide reductase

Biochemistry

Volumn 48, Issue 46, 2009, Pages 11134-11141

  Smith, Peter ^a   Zhou, Bingsen ^b   Ho, Nam ^a   Yuan, Yate Ching ^b   Su, Leila ^b   Tsai, Shiou Chuan ^a   Yen, Yun ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b CITY OF HOPE NATIONAL MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL FUNCTIONS; CELL CYCLE; DNA REPLICATIONS; IRON CENTERS; REGULATION MECHANISMS; RIBONUCLEOTIDE REDUCTASE; S-PHASE; SEQUENCE IDENTITY; SMALL SUBUNITS; STRUCTURAL DIFFERENCES; STRUCTURAL WORKS; STRUCTURE-FUNCTION CORRELATION; TRANSFER PATHWAY; X RAY CRYSTAL STRUCTURES;

LAWS AND LEGISLATION; NUCLEIC ACIDS;

CRYSTAL STRUCTURE;

RIBONUCLEOTIDE REDUCTASE; CELL CYCLE PROTEIN; CYSTEINE; ENZYME INHIBITOR; IRON; PROTEIN P53; RECOMBINANT PROTEIN; RIBONUCLEOSIDE DIPHOSPHATE REDUCTASE; RIBONUCLEOTIDE REDUCTASE M2; RRM2B PROTEIN, HUMAN; TYROSINE;

ARTICLE; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL CYCLE S PHASE; CRYSTAL STRUCTURE; DNA REPAIR; DNA REPLICATION; ENZYME ANALYSIS; ENZYME STRUCTURE; HUMAN; PRIORITY JOURNAL; X RAY ANALYSIS; BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; DRUG ANTAGONISM; DRUG DESIGN; GENETICS; HYDROGEN BOND; HYDROPHOBICITY; METABOLISM; PROTEIN QUATERNARY STRUCTURE; PROTEIN SECONDARY STRUCTURE; STATIC ELECTRICITY; X RAY CRYSTALLOGRAPHY;

BINDING SITES; CELL CYCLE PROTEINS; CRYSTALLOGRAPHY, X-RAY; CYSTEINE; DRUG DESIGN; ENZYME INHIBITORS; HUMANS; HYDROGEN BONDING; HYDROPHOBICITY; IRON; MODELS, MOLECULAR; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, SECONDARY; RECOMBINANT PROTEINS; RIBONUCLEOSIDE DIPHOSPHATE REDUCTASE; RIBONUCLEOTIDE REDUCTASES; STATIC ELECTRICITY; TUMOR SUPPRESSOR PROTEIN P53; TYROSINE;

EID: 72749119232     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi9001425     Document Type: Article

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