Sleep fragmentation reduces hippocampal CA1 pyramidal cell excitability and response to adenosine

Neuroscience Letters

Volumn 469, Issue 1, 2010, Pages 1-5

  Tartar, Jaime L ^a   McKenna, James T ^a   Ward, Christopher P ^a   McCarley, Robert W ^a   Strecker, Robert E ^a   Brown, Ritchie E ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

A1 receptor; Input resistance; Sleep interruption; Whole cell

Indexed keywords

ADENOSINE; ADENOSINE A1 RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; COGNITIVE DEFECT; CONTROLLED STUDY; HIPPOCAMPUS; HYPERPOLARIZATION; LONG TERM POTENTIATION; MALE; MEMBRANE POTENTIAL; NERVE CELL EXCITABILITY; NONHUMAN; PATCH CLAMP; PREDICTION; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; RAT; SLEEP DEPRIVATION; SLEEP DISORDER; UPREGULATION; WHOLE CELL;

ACTION POTENTIALS; ADENOSINE; ANIMALS; CA1 REGION, HIPPOCAMPAL; MALE; MEMBRANE POTENTIALS; PYRAMIDAL CELLS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, ADENOSINE A1; SLEEP DEPRIVATION; SYNAPTIC MEMBRANES; UP-REGULATION;

EID: 72649104727     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2009.11.032     Document Type: Article

References (30)

1. Arai A., Kessler M., and Lynch G. The effects of adenosine on the development of long-term potentiation. Neurosci. Lett. 119 (1990) 41-44
2. Arrigoni E., Chamberlin N.L., Saper C.B., and McCarley R.W. Adenosine inhibits basal forebrain cholinergic and non-cholinergic neurons in vitro. Neuroscience 140 (2006) 403-413
3. Basheer R., Bauer A., Elmenhorst D., Ramesh V., and McCarley R.W. Sleep deprivation upregulates A1 adenosine receptors in the rat basal forebrain. Neuroreport 18 (2007) 1895-1899
4. Basheer R., Strecker R.E., Thakkar M.M., and McCarley R.W. Adenosine and sleep-wake regulation. Prog. Neurobiol. 73 (2004) 379-396
5. Bonnet M.H. Sleep fragmentation. In: Lenfant C. (Ed). Sleep Deprivation (2005), Marcel Dekker, New York 103-117
6. Brown R.E., Franciosi S., McKenna J.T., Winston S., Yanagawa Y., and McCarley R.W. Electrophysiological and pharmacological characterization of cortically projecting basal forebrain neurons in the mouse. Soc. Neurosci. Abstr. (2008) 384.16
7. Brown R.E., Winston S., Basheer R., Thakkar M.M., and McCarley R.W. Electrophysiological characterization of neurons in the dorsolateral pontine rapid-eye-movement sleep induction zone of the rat: intrinsic membrane properties and responses to carbachol and orexins. Neuroscience 143 (2006) 739-755
8. Chen C., Hardy M., Ziang J., LaHoste G.J., and Bazan N.G. Altered NMDA receptor trafficking contributes to sleep deprivation-induced hippocampal synaptic and cognitive impairments. Biochem. Biophys. Res. Commun. 340 (2006) 435-440
9. Coleman R.M., Roffwarg H.P., Kennedy S.J., Guilleminault C., Cinque J., Cohn M.A., Karacan I., Kupfer D.J., Lemmi H., Miles L.E., Orr W.C., Phillips E.R., Roth T., Sassin J.F., Schmidt H.S., Weitzman E.D., and Dement W.C. Sleep-wake disorders based on a polysomnographic diagnosis. A national cooperative study. JAMA 247 (1982) 997-1003
10. Dunwiddie T.V., and Fredholm B.B. Adenosine A1 receptors inhibit adenylate cyclase activity and neurotransmitter release and hyperpolarize pyramidal neurons in rat hippocampus. J. Pharmacol. Exp. Ther. 249 (1989) 1-7
11. Dunwiddie T.V., and Haas H.L. Adenosine increases synaptic facilitation in the in vitro rat hippocampus: evidence for a presynaptic site of action. J. Physiol. 369 (1985) 365-377
12. Dunwiddie T.V., and Masino S.A. The role and regulation of adenosine in the central nervous system. Ann. Rev. Neurosci. 24 (2001) 31-55
13. Elmenhorst D., Basheer R., McCarley R.W., and Bauer A. Sleep deprivation increases A(1) adenosine receptor density in the rat brain. Brain Res. 1258 (2009) 53-58
14. Elmenhorst D., Meyer P.T., Winz O.H., Matusch A., Ermert J., Coenen H.H., Basheer R., Haas H.L., Zilles K., and Bauer A. Sleep deprivation increases A1 adenosine receptor binding in the human brain: a positron emission tomography study. J. Neurosci. 27 (2007) 2410-2415
15. Gerber U., Greene R.W., Haas H.L., and Stevens D.R. Characterization of inhibition mediated by adenosine in the hippocampus of the rat in vitro. J. Physiol. 417 (1989) 567-578
16. Greene R.W., and Haas H.L. The electrophysiology of adenosine in the mammalian central nervous system. Prog. Neurobiol. 36 (1991) 329-341
17. Huston J.P., Haas H.L., Boix F., Pfister M., Decking U., Schrader J., and Schwarting R.K. Extracellular adenosine levels in neostriatum and hippocampus during rest and activity periods of rats. Neuroscience 73 (1996) 99-107
18. Kopp C., Longordo F., Nicholson J.R., and Luthi A. Insufficient sleep reversibly alters bidirectional synaptic plasticity and NMDA receptor function. J. Neurosci. 26 (2006) 12456-12465
19. Longordo F., Kopp C., Mishina M., Lujan R., and Luthi A. NR2A at CA1 synapses is obligatory for the susceptibility of hippocampal plasticity to sleep loss. J. Neurosci. 29 (2009) 9026-9041
20. McCoy J.G., Tartar J.L., Bebis A.C., Ward C.P., McKenna J.T., Baxter M.G., McGaughy J., McCarley R.W., and Strecker R.E. Experimental sleep fragmentation impairs attentional set-shifting in rats. Sleep 30 (2007) 52-60
21. McDermott C.M., Hardy M.N., Bazan N.G., and Magee J.C. Sleep deprivation-induced alterations in excitatory synaptic transmission in the CA1 region of the rat hippocampus. J. Physiol. 570 (2006) 553-565
22. McDermott C.M., LaHoste G.J., Chen C., Musto A., Bazan N.G., and Magee J.C. Sleep deprivation causes behavioral, synaptic, and membrane excitability alterations in hippocampal neurons. J. Neurosci. 23 (2003) 9687-9695
23. McKenna J.T., Tartar J.L., Ward C.P., Thakkar M.M., Cordeira J.W., McCarley R.W., and Strecker R.E. Sleep fragmentation elevates behavioral, electrographic and neurochemical measures of sleepiness. Neuroscience 146 (2007) 1462-1473
24. Moyer J.R., Thomson L.T., and Disterhoft J.F. Trace eyeblink conditioning increases CA1 excitability in a transient and learning-specific manner. J. Neurosci. 16 (1996) 5536-5546
25. Porkka-Heiskanen T., Strecker R.E., and McCarley R.W. Brain site-specificity of extracellular adenosine concentration changes during sleep deprivation and spontaneous sleep: an in vivo microdialysis study. Neuroscience 99 (2000) 507-517
26. Stepanski E.J. The effect of sleep fragmentation on daytime function. Sleep 25 (2002) 268-276
27. Tartar J.L., Ward C.P., McKenna J.T., Thakkar M.M., Arrigoni E., McCarley R.W., Brown R.E., and Strecker R.E. Hippocampal synaptic plasticity and spatial learning are impaired in a rat model of sleep fragmentation. Eur. J. Neurosci. 23 (2006) 2739-2748
28. Thomson S.M., Haas H.L., and Gaehwiler B.H. Comparison of the actions of adenosine at pre- and postsynaptic receptors in the rat hippocampus in vitro. J. Physiol. 451 (1992) 347-363
29. Ward C.P., McCarley R.W., and Strecker R.E. Experimental sleep fragmentation impairs spatial reference but not working memory in Fischer/Brown Norway rats. J. Sleep Res. 18 (2009) 238-244
30. Wetherington J.P., and Lambert N.A. Differential desensitization of responses mediated by presynaptic and postsynaptic A1 adenosine receptors. J. Neurosci. 22 (2002) 1248-1255