Low bone mineral density in adult patients with moderate to severe atopic dermatitis

British Journal of Dermatology

Volumn 161, Issue 6, 2009, Pages 1248-1254

  Haeck, I M ^a   Hamdy, N A T ^b   Timmer De Mik, L ^a   Lentjes, E G W M ^a   Verhaar, H J J ^a   Knol, M J ^a   De Bruin Weller, M S ^a   Bruijnzeel Koomen, C A F M ^a  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Atopic dermatitis; Bone mineral density; Topical corticosteroids

Indexed keywords

25 HYDROXYVITAMIN D; ALKALINE PHOSPHATASE BONE ISOENZYME; CARBOXY TERMINAL TELOPEPTIDE; CORTICOSTEROID; IMMUNOGLOBULIN E; OSTEOCLAST DIFFERENTIATION FACTOR; OSTEOPROTEGERIN; PARATHYROID HORMONE; RECEPTOR ACTIVATOR OF NUCLEAR FACTOR KAPPA B; THYMUS AND ACTIVATION REGULATED CHEMOKINE;

ADOLESCENT; ADULT; AGED; ARTICLE; ATOPIC DERMATITIS; BONE DENSITY; BONE METABOLISM; CONTROLLED STUDY; CORTICOSTEROID THERAPY; DISEASE ASSOCIATION; DISEASE COURSE; DISEASE SEVERITY; DOSE CALCULATION; DUAL ENERGY X RAY ABSORPTIOMETRY; ENZYME BLOOD LEVEL; FEMALE; HIP; HUMAN; IMMUNOGLOBULIN BLOOD LEVEL; LIFESTYLE; LUMBAR SPINE; MAJOR CLINICAL STUDY; MALE; OSTEOPENIA; OSTEOPOROSIS; PARATHYROID HORMONE BLOOD LEVEL; PRESCRIPTION; PREVALENCE; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN DETERMINATION; SEX DIFFERENCE; VITAMIN BLOOD LEVEL;

ABSORPTIOMETRY, PHOTON; ADRENAL CORTEX HORMONES; ADULT; AGED; AGED, 80 AND OVER; BONE DENSITY; DERMATITIS, ATOPIC; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HUMANS; LIFE STYLE; MALE; MIDDLE AGED; OSTEOPOROSIS; PREVALENCE; QUESTIONNAIRES; RISK FACTORS; SEVERITY OF ILLNESS INDEX; YOUNG ADULT;

EID: 72649103377     PISSN: 00070963     EISSN: 13652133     Source Type: Journal    
DOI: 10.1111/j.1365-2133.2009.09327.x     Document Type: Article

References (30)

1. Kay J, Gawkrodger DJ, Mortimer MJ et al. The prevalence of childhood atopic eczema in a general population. J Am Acad Dermatol 1994 30 : 35 9.
2. Laughter D, Istvan JA, Tofte SJ et al. The prevalence of atopic dermatitis in Oregon schoolchildren. J Am Acad Dermatol 2000 43 : 649 655.
3. Bieber T. Atopic dermatitis. N Engl J Med 2008 358 : 1483 1494.
4. Munro DD. Topical corticosteroid therapy and its effect on the hypothalamic-pituitary-adrenal axis. Dermatologica 1976 152 (Suppl. 1 173 180.
5. Kristmundsdottir F, David TJ. Growth impairment in children with atopic eczema. J R Soc Med 1987 80 : 9 12.
6. Cowan A, Klauder JV. Frequency of occurrence of cataract in atopic dermatitis. Arch Ophthal 1950 43 : 759 768.
7. Carruthers JA, August PJ, Staughton RC. Observations on the systemic effect of topical clobetasol propionate (Dermovate). Br Med J 1975 4 : 203 204.
8. Report of a WHO Study Group. Assessment of fracture risk and its application to screening for postmenopausal osteoporosis. World Health Organ Tech Rep Ser 1994 843 : 1 129.
9. Bernstein CN, Leslie WD. The pathophysiology of bone disease in gastrointestinal disease. Eur J Gastroenterol Hepatol 2003 15 : 857 864.
10. Bernstein CN, Leslie WD, Leboff MS. AGA technical review on osteoporosis in gastrointestinal diseases. Gastroenterology 2003 124 : 795 841.
11. Da Silva JA, Jacobs JW, Kirwan JR et al. Safety of low dose glucocorticoid treatment in rheumatoid arthritis: published evidence and prospective trial data. Ann Rheum Dis 2006 65 : 285 293.
12. Walsh NC, Crotti TN, Goldring SR et al. Rheumatic diseases: the effects of inflammation on bone. Immunol Rev 2005 208 : 228 251.
13. Hanifin JM, Rajka G. Diagnostic features of atopic dermatitis. Acta Derm Venereol 1980 92 : 44 7.
14. Hijnen D, De Bruin-Weller M, Oosting B et al. Serum thymus and activation-regulated chemokine (TARC) and cutaneous T cell-attracting chemokine (CTACK) levels in allergic diseases: TARC and CTACK are disease-specific markers for atopic dermatitis. J Allergy Clin Immunol 2004 113 : 334 340.
15. Holick MF. Vitamin D deficiency. N Engl J Med 2007 357 : 266 281.
16. Holick MF. Optimal vitamin D status for the prevention and treatment of osteoporosis. Drugs Aging 2007 24 : 1017 1029.
17. Bartram SA, Peaston RT, Rawlings DJ et al. Multifactorial analysis of risk factors for reduced bone mineral density in patients with Crohn's disease. World J Gastroenterol 2006 12 : 5680 5686.
18. Sasaki N, Kusano E, Ando Y et al. Changes in osteoprotegerin and markers of bone metabolism during glucocorticoid treatment in patients with chronic glomerulonephritis. Bone 2002 30 : 853 858.
19. Sasaki N, Kusano E, Ando Y et al. Effects of low-dose prednisone on bone metabolism. J Bone Miner Res 2005 20 : 464 470.
20. Vidal NO, Brandstrom H, Jonsson KB et al. Osteoprotegerin mRNA is expressed in primary human osteoblast-like cells: down-regulation by glucocorticoids. J Endocrinol 1998 159 : 191 195.
21. Sasaki N, Kusano E, Ando Y et al. Glucocorticoid decreases circulating osteoprotegerin (OPG): possible mechanism for glucocorticoid induced osteoporosis. Nephrol Dial Transplant 2001 16 : 479 482.
22. Kearns AE, Khosla S, Kostenuik PJ. Receptor activator of nuclear factor kappaB ligand and osteoprotegerin regulation of bone remodeling in health and disease. Endocr Rev 2008 29 : 155 192.
23. Nymann P, Kollerup G, Jemec GB et al. Decreased bone mineral density in patients with pustulosis palmaris et plantaris. Dermatology 1996 192 : 307 311.
24. Millard TP, Antoniades L, Evans AV et al. Bone mineral density of patients with chronic plaque psoriasis. Clin Exp Dermatol 2001 26 : 446 448.
25. Aalto-Korte K, Turpeinen M. Bone mineral density in patients with atopic dermatitis. Br J Dermatol 1997 136 : 172 175.
26. van Staa TP, Geusens P, Bijlsma JW et al. Clinical assessment of the long-term risk of fracture in patients with rheumatoid arthritis. Arthritis Rheum 2006 54 : 3104 3112. (Pubitemid 44622079)
27. Gough AK, Lilley J, Eyre S et al. Generalised bone loss in patients with early rheumatoid arthritis. Lancet 1994 344 : 23 7.
28. Lodder MC, de Jong Z, Kostense PJ et al. Bone mineral density in patients with rheumatoid arthritis: relation between disease severity and low bone mineral density. Ann Rheum Dis 2004 63 : 1576 1580.
29. Laan RF, Buijs WC, Verbeek AL et al. Bone mineral density in patients with recent onset rheumatoid arthritis: influence of disease activity and functional capacity. Ann Rheum Dis 1993 52 : 21 6.
30. Vahavihu K, Ylianttila L, Salmelin R et al. Heliotherapy improves vitamin D balance and atopic dermatitis. Br J Dermatol 2008 158 : 1323 1328.