The results of the RE-LY study promise more effective, safer and easier prevention of embolic complications in patients with non-valvular atrial fibrillation;Výsledky studie RE-LY slibují účinně jší, bezpečnější a jednodušší prevenci embolických komplikací u nemocných s nevalvulární fibrilací síní

Vnitrni Lekarstvi

Volumn 55, Issue 11, 2009, Pages 1085-1088

  Vojáček, Jan ^a  

^a UNIVERSITY HOSPITAL HRADEC KRALOVE   (Czech Republic)

Author keywords

Cerebrovascular event; Dabigatran; Non valvular atrial fibrillation; Systemic embolisation; Warfarin

Indexed keywords

DABIGATRAN; WARFARIN;

ARTIFICIAL EMBOLISM; BLEEDING; BRAIN HEMORRHAGE; CONTROLLED STUDY; EMBOLISM; HEART ATRIUM FIBRILLATION; HUMAN; INCIDENCE; LABORATORY TEST; MAJOR CLINICAL STUDY; MONITORING; MORTALITY; REVIEW; RISK FACTOR;

ANTICOAGULANTS; ATRIAL FIBRILLATION; BENZIMIDAZOLES; EMBOLISM; HUMANS; PYRIDINES; WARFARIN;

EID: 72549105159     PISSN: 0042773X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (10)

1. Ezekowitz MD, Connolly S, Parekh A et al. Rationale and design of RE-LY: randomized evaluation of long-term anticoagulant therapy, warfarin, compared with dabigatran. Am Heart J 2009; 157: 805-810.
2. Greenlee RT, Vidaillet H. Recent progress in the epidemiology of atrial fibrillation. Review. Curr Opin Cardiol 2005; 20: 7-14.
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4. Hart RG, Pearce LA, Aguilar MI. Meta-analysis: antithrombotic therapy to prevent stroke in patients who have nonvalvular atrial fibrillation. Ann Intern Med 2007; 146: 857-867.
5. Fuster V, Rydén LE, Cannom DS et al. ACC/AHA/ESC 2006 guidelines for the management of patients with atrial fibrillation: full text A report of the American College of Cardiology/American Heart Association Task Force on practice guidelines and the European Society of Cardiology Committee for Practice Guidelines (Writing Committee to Revise the 2001 Guidelines for the Management of Patients With Atrial Fibrillation) developed in collaboration with the European Heart Rhythm Association and the Heart Rhythm Society. Europace 2006; 8: 651-745.
6. van Walraven C, Hart RG, Wells GA et al. A clinical prediction rule to identify patients with atrial fibrillation and a low risk for stroke while taking aspirin. Arch Intern Med 2003; 163: 936-943.
7. Connolly S, Pogue J, Hart R et al. ACTIVE Investigators. Clopidogrel plus aspirin versus oral anticoagulation for atrial fibrillation in the Atrial fibrillation Clopidogrel Trial with Irbesartan for prevention of Vascular Events (ACTIVE W): a randomised controlled trial. Lancet 2006; 367: 1903-1912.
8. Connolly SJ, Pogue J, Hart RG et al. ACTIVE Investigators. Effect of clopidogrel added to aspirin in patients with atrial fibrillation. N Engl J Med 2009; 360: 2066-2078.
9. Connolly S, Ezekowitz MD, Yusuf S et al. RE-LY Steering Committee and Investigators. Dabigatran versus Warfarin in Patients with Atrial Fibrillation. N Engl J Med 2009; 361: 1139-1151.
10. Gage BF. Can We Rely on RE-LY? N Engl J Med 2009; 361: 1200-1202.