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Volumn 11, Issue 6, 2009, Pages 456-462

Direct renin inhibition: An update

Author keywords

[No Author keywords available]

Indexed keywords

ALISKIREN; ALISKIREN PLUS HYDROCHLOROTHIAZIDE; ANGIOTENSIN RECEPTOR ANTAGONIST; ATENOLOL; BRAIN NATRIURETIC PEPTIDE; DIURETIC AGENT; HYDROCHLOROTHIAZIDE; IRBESARTAN; LOSARTAN; PLACEBO; PRORENIN RECEPTOR; RAMIPRIL; RENIN; VALSARTAN;

EID: 72549102335     PISSN: 15226417     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11906-009-0077-7     Document Type: Review
Times cited : (9)

References (26)
  • 1
    • 36348998335 scopus 로고    scopus 로고
    • Aliskiren, a direct renin inhibitor, provides antihypertensive efficacy and excellent tolerability independent of age or gender in patients with hypertension [abstract]
    • B. Dahlöf D.R. Anderson V. Arora, et al. 2007 Aliskiren, a direct renin inhibitor, provides antihypertensive efficacy and excellent tolerability independent of age or gender in patients with hypertension [abstract] J Clin Hypertens 9 SupplA A157
    • (2007) J Clin Hypertens , vol.9 , Issue.SUPPLA , pp. 157
    • Dahlöf, B.1    Anderson, D.R.2    Arora, V.3
  • 2
    • 34447521458 scopus 로고    scopus 로고
    • Efficacy and safety of combined use of aliskiren and valsartan in patients with hypertension: a randomised, double-blind trial
    • DOI 10.1016/S0140-6736(07)61124-6, PII S0140673607611246
    • S. Oparil S.A. Yarows S. Patel, et al. 2007 Efficacy and safety of combined use of aliskiren and valsartan in patients with hypertension: a randomised, double-blind trial Lancet 370 221 229 10.1016/S0140-6736(07)61124-6 1:CAS:528:DC%2BD2sXnvF2gsrc%3D 17658393 (Pubitemid 47069535)
    • (2007) Lancet , vol.370 , Issue.9583 , pp. 221-229
    • Oparil, S.1    Yarows, S.A.2    Patel, S.3    Fang, H.4    Zhang, J.5    Satlin, A.6
  • 3
    • 33645757377 scopus 로고    scopus 로고
    • Aliskiren, a novel orally effective renin inhibitor, provides antihypertensive efficacy and placebo-like tolerability similar to an AT1-receptor blocker in hypertensive patients [abstract]
    • 10.1016/j.amjhyper.2004.03.279
    • A.H. Gradman R.E. Schmieder R.L. Lins, et al. 2004 Aliskiren, a novel orally effective renin inhibitor, provides antihypertensive efficacy and placebo-like tolerability similar to an AT1-receptor blocker in hypertensive patients [abstract] Am J Hypertens 17 S108 10.1016/j.amjhyper.2004.03.279
    • (2004) Am J Hypertens , vol.17 , pp. 108
    • Gradman, A.H.1    Schmieder, R.E.2    Lins, R.L.3
  • 4
    • 0347479295 scopus 로고    scopus 로고
    • Blood Pressure Lowering in Essential Hypertension with an Oral Renin Inhibitor, Aliskiren
    • DOI 10.1161/01.HYP.0000101688.17370.87
    • A. Stanton C. Jensen J. Nussberger E. O'Brien 2003 Blood pressure lowering in essential hypertension with an oral renin inhibitor, aliskiren Hypertension 42 1137 1143 10.1161/01.HYP.0000101688.17370.87 1:CAS:528:DC%2BD3sXpsVGisrg%3D 14597641 (Pubitemid 37549068)
    • (2003) Hypertension , vol.42 , Issue.6 , pp. 1137-1143
    • Stanton, A.1    Jensen, C.2    Nussberger, J.3    OBrien, E.4
  • 5
    • 60549087324 scopus 로고    scopus 로고
    • Long-term antihypertensive efficacy and safety of the oral direct renin inhibitor aliskiren: A 12-month randomized, double-blind comparator trial with hydrochlorothiazide
    • 10.1161/CIRCULATIONAHA.107.750745 1:CAS:528:DC%2BD1MXpt1Cmsg%3D%3D 19139391
    • R.E. Schmieder T. Philipp J. Guerediaga, et al. 2009 Long-term antihypertensive efficacy and safety of the oral direct renin inhibitor aliskiren: a 12-month randomized, double-blind comparator trial with hydrochlorothiazide Circulation 119 417 425 10.1161/CIRCULATIONAHA.107.750745 1:CAS:528:DC%2BD1MXpt1Cmsg%3D%3D 19139391
    • (2009) Circulation , vol.119 , pp. 417-425
    • Schmieder, R.E.1    Philipp, T.2    Guerediaga, J.3
  • 7
    • 34548087645 scopus 로고    scopus 로고
    • Aliskiren, a novel renin inhibitor, provides long-term suppression of the renin system, when used alone or in combination with hydrochlorothiazide in the treatment of hypertension
    • J. Pool A. Gradman R. Kolloch, et al. 2006 Aliskiren, a novel renin inhibitor, provides long-term suppression of the renin system, when used alone or in combination with hydrochlorothiazide in the treatment of hypertension Eur Heart J 119 suppl27 790
    • (2006) Eur Heart J , vol.119 , Issue.SUPPL27 , pp. 790
    • Pool, J.1    Gradman, A.2    Kolloch, R.3
  • 8
    • 75149128934 scopus 로고    scopus 로고
    • Maintenance of blood-pressure-lowering effect following a missed dose of aliskiren, irbesartan or ramipril: Results of a randomized, double-blind study
    • May 21 (Epub ahead of print)
    • Palatini P, Jung W, Shlyakhto E, et al.: Maintenance of blood-pressure-lowering effect following a missed dose of aliskiren, irbesartan or ramipril: results of a randomized, double-blind study. J Hum Hypertens 2009 May 21 (Epub ahead of print).
    • (2009) J Hum Hypertens
    • Palatini, P.1    Jung, W.2    Shlyakhto, E.3
  • 9
    • 33947182655 scopus 로고    scopus 로고
    • Aliskiren, an Oral Renin Inhibitor, Provides Dose-Dependent Efficacy and Sustained 24-Hour Blood Pressure Control in Patients With Hypertension
    • DOI 10.1016/j.jacc.2006.11.032, PII S0735109706032037
    • B.H. Oh J. Mitchell J.R. Herron, et al. 2007 Aliskiren, an oral renin inhibitor, provides dose-dependent efficacy and sustained 24-hour blood pressure control in patients with hypertension J Am Coll Cardiol 49 1157 1163 10.1016/j.jacc.2006.11.032 1:CAS:528:DC%2BD2sXjtVagurk%3D 17367658 (Pubitemid 46400330)
    • (2007) Journal of the American College of Cardiology , vol.49 , Issue.11 , pp. 1157-1163
    • Oh, B.-H.1    Mitchell, J.2    Herron, J.R.3    Chung, J.4    Khan, M.5    Keefe, D.L.6
  • 10
    • 33845366982 scopus 로고    scopus 로고
    • Renin inhibition with aliskiren provides additive antihypertensive efficacy when used in combination with hydrochlorothiazide
    • DOI 10.1097/HJH.0b013e3280103a6b, PII 0000487220070100000030
    • A. Villamil S.G. Chrysant D. Calhoun, et al. 2007 Renin inhibition with aliskiren provides additive antihypertensive efficacy when used in combination with hydrochlorothiazide J Hypertens 25 217 226 10.1097/HJH.0b013e3280103a6b 1:CAS:528:DC%2BD28Xht1OhtrnM 17143194 (Pubitemid 44885684)
    • (2007) Journal of Hypertension , vol.25 , Issue.1 , pp. 217-226
    • Villamil, A.1    Chrysant, S.G.2    Calhoun, D.3    Schober, B.4    Hsu, H.5    Matrisciano-Dimichino, L.6    Zhang, J.7
  • 12
    • 56749085787 scopus 로고    scopus 로고
    • Effects of the direct renin inhibitor aliskiren and atenolol alone or in combination in patients with hypertension
    • 10.1177/1470320308096411 1:CAS:528:DC%2BD1cXhsFCku7jI 18957387
    • R. Dietz R. Dechend C.M. Yu, et al. 2008 Effects of the direct renin inhibitor aliskiren and atenolol alone or in combination in patients with hypertension J Renin Angiotensin Aldosterone Syst 9 163 175 10.1177/ 1470320308096411 1:CAS:528:DC%2BD1cXhsFCku7jI 18957387
    • (2008) J Renin Angiotensin Aldosterone Syst , vol.9 , pp. 163-175
    • Dietz, R.1    Dechend, R.2    Yu, C.M.3
  • 13
    • 34247644329 scopus 로고    scopus 로고
    • Aliskiren, the First Renin Inhibitor for Treating Hypertension: Reactive Renin Secretion May Limit Its Effectiveness
    • DOI 10.1016/j.amjhyper.2007.04.001, PII S0895706107001732
    • J.E. Sealey J.H. Laragh 2007 Aliskiren, the first renin inhibitor for treating hypertension: reactive renin secretion may limit its effectiveness Am J Hypertens 20 587 597 10.1016/j.amjhyper.2007.04.001 1:CAS:528: DC%2BD2sXkvF2jt7k%3D 17485026 (Pubitemid 46678721)
    • (2007) American Journal of Hypertension , vol.20 , Issue.5 , pp. 587-597
    • Sealey, J.E.1    Laragh, J.H.2
  • 14
    • 37349091464 scopus 로고    scopus 로고
    • Interpretation of plasma renin concentration in patients receiving aliskiren therapy
    • DOI 10.1161/HYPERTENSIONAHA.107.101287
    • D.J. Campbell 2008 Interpretation of plasma renin concentration in patients receiving aliskiren therapy Hypertension 51 15 18 10.1161/ HYPERTENSIONAHA.107.101287 1:CAS:528:DC%2BD2sXhsVagurbL 17984367 (Pubitemid 350307093)
    • (2008) Hypertension , vol.51 , Issue.1 , pp. 15-18
    • Campbell, D.J.1
  • 15
    • 42049104395 scopus 로고    scopus 로고
    • The renin rise with aliskiren: It's simply stoichiometry
    • DOI 10.1161/HYPERTENSIONAHA.108.109967, PII 0000426820080400000031
    • A.H. Danser A. Charney D.L. Feldman, et al. 2008 The renin rise with aliskiren: it's simply stoichiometry Hypertension 51 e27 e28 10.1161/HYPERTENSIONAHA.108.109967 1:CAS:528:DC%2BD1cXmsFamtbg%3D 18285609 (Pubitemid 351654714)
    • (2008) Hypertension , vol.51 , Issue.4
    • Jan Danser, A.H.1    Charney, A.2    Feldman, D.L.3    Nussberger, J.4    Fisher, N.5    Hollenberg, N.6
  • 16
    • 79954528566 scopus 로고    scopus 로고
    • Aliskiren does not cause paradoxical rises in blood pressure [abstract P-56]
    • A. Stanton A.H. Gradman R. Schmieder, et al. 2009 Aliskiren does not cause paradoxical rises in blood pressure [abstract P-56] J Clin Hypertens 11s1 A39
    • (2009) J Clin Hypertens , vol.111 , pp. 39
    • Stanton, A.1    Gradman, A.H.2    Schmieder, R.3
  • 17
    • 34848907212 scopus 로고    scopus 로고
    • Aliskiren, a novel renin inhibitor, is renoprotective in a model of advanced diabetic nephropathy in rats
    • DOI 10.1007/s00125-007-0795-9
    • D.J. Kelly Y. Zhang G. Moe, et al. 2007 Aliskiren, a novel renin inhibitor, is renoprotective in a model of advanced diabetic nephropathy in rats Diabetologia 50 2398 2404 10.1007/s00125-007-0795-9 1:CAS:528: DC%2BD2sXhtFSlsL%2FI 17828524 (Pubitemid 47512400)
    • (2007) Diabetologia , vol.50 , Issue.11 , pp. 2398-2404
    • Kelly, D.J.1    Zhang, Y.2    Moe, G.3    Naik, G.4    Gilbert, R.E.5
  • 18
    • 46449118638 scopus 로고    scopus 로고
    • Effects of aliskiren on blood pressure, albuminuria, and (pro)renin receptor expression in diabetic TG(mRen-2)27 rats
    • 10.1161/HYPERTENSIONAHA.107.108845 1:CAS:528:DC%2BD1cXntVaisL0%3D 18490518
    • D.L. Feldman L. Jin H. Xuan, et al. 2008 Effects of aliskiren on blood pressure, albuminuria, and (pro)renin receptor expression in diabetic TG(mRen-2)27 rats Hypertension 52 130 136 10.1161/HYPERTENSIONAHA.107.108845 1:CAS:528:DC%2BD1cXntVaisL0%3D 18490518
    • (2008) Hypertension , vol.52 , pp. 130-136
    • Feldman, D.L.1    Jin, L.2    Xuan, H.3
  • 19
    • 47049093197 scopus 로고    scopus 로고
    • Renal and hormonal responses to direct renin inhibition with aliskiren in healthy humans
    • 10.1161/CIRCULATIONAHA.108.767202 1:CAS:528:DC%2BD1cXnt1ehs70%3D 18559696
    • N.D. Fisher A.H. Jan Danser J. Nussberger, et al. 2008 Renal and hormonal responses to direct renin inhibition with aliskiren in healthy humans Circulation 117 3199 3205 10.1161/CIRCULATIONAHA.108.767202 1:CAS:528: DC%2BD1cXnt1ehs70%3D 18559696
    • (2008) Circulation , vol.117 , pp. 3199-3205
    • Fisher, N.D.1    Jan Danser, A.H.2    Nussberger, J.3
  • 20
    • 0036266596 scopus 로고    scopus 로고
    • Pivotal role of the renin/prorenin receptor in angiotensin II production and cellular responses to renin
    • 1:CAS:528:DC%2BD38XktlWlu78%3D 12045255
    • G. Nguyen F. Delarue C. Burckle, et al. 2002 Pivotal role of the renin/prorenin receptor in angiotensin II production and cellular responses to renin J Clin Invest 109 1417 1427 1:CAS:528:DC%2BD38XktlWlu78%3D 12045255
    • (2002) J Clin Invest , vol.109 , pp. 1417-1427
    • Nguyen, G.1    Delarue, F.2    Burckle, C.3
  • 22
    • 44849114597 scopus 로고    scopus 로고
    • Aliskiren combined with losartan in type 2 diabetes and nephropathy
    • DOI 10.1056/NEJMoa0708379
    • H.H. Parving F. Persson J.B. Lewis AVOID Study Investigators, et al. 2008 Aliskiren combined with losartan in type 2 diabetes and nephropathy N Engl J Med 358 2433 2446 10.1056/NEJMoa0708379 1:CAS:528:DC%2BD1cXmvFKmtLY%3D 18525041 (Pubitemid 351793017)
    • (2008) New England Journal of Medicine , vol.358 , Issue.23 , pp. 2433-2446
    • Parving, H.-H.1    Persson, F.2    Lewis, J.B.3    Lewis, E.J.4    Hollenberg, N.K.5
  • 23
    • 61349170589 scopus 로고    scopus 로고
    • Effect of the direct renin inhibitor aliskiren, the angiotensin receptor blocker losartan, or both on left ventricular mass in patients with hypertension and left ventricular hypertrophy
    • 10.1161/CIRCULATIONAHA.108.826214 1:CAS:528:DC%2BD1MXpt1eksA%3D%3D 19153265
    • S.D. Solomon E. Appelbaum W. A. i. L. V. H. Manning, et al. 2009 Effect of the direct renin inhibitor aliskiren, the angiotensin receptor blocker losartan, or both on left ventricular mass in patients with hypertension and left ventricular hypertrophy Circulation 119 530 537 10.1161/CIRCULATIONAHA.108. 826214 1:CAS:528:DC%2BD1MXpt1eksA%3D%3D 19153265
    • (2009) Circulation , vol.119 , pp. 530-537
    • Solomon, S.D.1    Appelbaum, E.2    Manning, W.A.I.L.V.H.3
  • 24
    • 57449084151 scopus 로고    scopus 로고
    • Renin inhibition improves cardiac function and remodeling after myocardial infarction independent of blood pressure
    • 10.1161/HYPERTENSIONAHA.108.116350 1:CAS:528:DC%2BD1cXhsVWrt7vN 18955663
    • D. Westermann A. Riad O. Lettau, et al. 2008 Renin inhibition improves cardiac function and remodeling after myocardial infarction independent of blood pressure Hypertension 52 1068 1075 10.1161/HYPERTENSIONAHA.108.116350 1:CAS:528:DC%2BD1cXhsVWrt7vN 18955663
    • (2008) Hypertension , vol.52 , pp. 1068-1075
    • Westermann, D.1    Riad, A.2    Lettau, O.3
  • 26
    • 79958249630 scopus 로고    scopus 로고
    • Effects of the oral direct renin inhibitor aliskiren in patients with symptomatic heart failure
    • 10.1161/CIRCHEARTFAILURE.107.740704 1:CAS:528:DC%2BD1cXosFGnsLY%3D 19808266
    • J.J.V. McMurray B. Pitt R. f. t. A. O. o. H. F. T. Latini, et al. 2008 Effects of the oral direct renin inhibitor aliskiren in patients with symptomatic heart failure Circ Heart Fail 1 17 24 10.1161/CIRCHEARTFAILURE.107. 740704 1:CAS:528:DC%2BD1cXosFGnsLY%3D 19808266
    • (2008) Circ Heart Fail , vol.1 , pp. 17-24
    • McMurray, J.J.V.1    Pitt, B.2    Latini, R.F.T.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.