Urea clearance: A new method to register local changes in blood flow in rat skeletal muscle based on microdialysis

Clinical Physiology and Functional Imaging

Volumn 30, Issue 1, 2010, Pages 57-63

  Farnebo, S ^a   Samuelsson, A ^a   Henriksson, J ^b   Karlander, L E ^a   Sjoberg F ^a,c  

^a LINKÖPING UNIVERSITY HOSPITAL   (Sweden)

^b KAROLINSKA INSTITUTE   (Sweden)

^c LINKÖPING UNIVERSITY   (Sweden)

Author keywords

Extracellular fluid; Glucose; Lactate; Metabolism; Recovery

Indexed keywords

GLUCOSE; LACTIC ACID; NORADRENALIN; PYRUVIC ACID;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; GRACILIS MUSCLE; MALE; METABOLIC CLEARANCE RATE; METABOLITE; MICRODIALYSIS; MUSCLE BLOOD FLOW; MUSCLE PERFUSION; NONHUMAN; PRIORITY JOURNAL; RAT; REPRODUCIBILITY; SENSITIVITY ANALYSIS; SPRAGUE DAWLEY RAT; UREA BLOOD LEVEL; UREA CLEARANCE; UREA CYCLE;

ANIMALS; BLOOD GLUCOSE; LACTIC ACID; MALE; MICRODIALYSIS; MUSCLE, SKELETAL; NOREPINEPHRINE; PYRUVIC ACID; RATS; RATS, SPRAGUE-DAWLEY; REGIONAL BLOOD FLOW; UREA; VASOCONSTRICTOR AGENTS;

EID: 72549083779     PISSN: 14750961     EISSN: 1475097X     Source Type: Journal    
DOI: 10.1111/j.1475-097X.2009.00904.x     Document Type: Article

References (24)

1. Abrahamsson P, Winso O. An assessment of calibration and performance of the microdialysis system. J Pharm Biomed Anal 2005, 39:730-734.
2. Boutsiouki P, Thompson JP, Clough GF. Effects of local blood flow on the percutaneous absorption of the organophosphorus compound malathion: a microdialysis study in man. Arch Toxicol 2001, 75:321-328.
3. Brunton LL, Lazo J, Parker K. Goodman and Gillman′s The Pharmacological Basis of Therapeutics 2005, McGraw Hill Publishing, New York, USA
4. Chaurasia CS. In vivo microdialysis sampling: theory and applications. Biomed Chromatogr 1999, 13:317-332.
5. Clough GF, Boutsiouki P, Church MK, Michel CC. Effects of blood flow on the in vivo recovery of a small diffusible molecule by microdialysis in human skin. J Pharmacol Exp Ther 2002, 302:681-686.
6. Delgado JM, DeFeudis FV, Roth RH, Ryugo DK, Mitruka BM. Dialytrode for long term intracerebral perfusion in awake monkeys. Arch Int Pharmacodyn Ther 1972, 198:9-21.
7. Hickner RC, Rosdahl H, Borg I, Ungerstedt U, Jorfeldt L, Henriksson J. Ethanol may be used with the microdialysis technique to monitor blood flow changes in skeletal muscle: dialysate glucose concentration is blood-flow-dependent. Acta Physiol Scand 1991, 143:355-356.
8. Hickner RC, Bone D, Ungerstedt U, Jorfeldt L, Henriksson J. Muscle blood flow during intermittent exercise: comparison of the microdialysis ethanol technique and 133Xe clearance. Clin Sci (Lond) 1994, 86:15-25.
9. Hickner RC, Ekelund U, Mellander S, Ungerstedt U, Henriksson J. Muscle blood flow in cats: comparison of microdialysis ethanol technique with direct measurement. J Appl Physiol 1995, 79:638-647.
10. Newman JM, Di Maria CA, Rattigan S, Clark MG. Nutritive blood flow affects microdialysis O/I ratio for [(14)C]ethanol and (3)H(2)O in perfused rat hindlimb. Am J Physiol Heart Circ Physiol 2001, 281:H2731-H2737.
11. Newman JM, Rattigan S, Clark MG. Nutritive blood flow improves interstitial glucose and lactate exchange in perfused rat hindlimb. Am J Physiol Heart Circ Physiol 2002, 283:H186-H192.
12. Nowak G, Ungerstedt J, Wernerman J, Ungerstedt U, Ericzon BG. Clinical experience in continuous graft monitoring with microdialysis early after liver transplantation. Br J Surg 2002, 89:1169-1175.
13. Rosdahl H, Ungerstedt U, Jorfeldt L, Henriksson J. Interstitial glucose and lactate balance in human skeletal muscle and adipose tissue studied by microdialysis. J Physiol 1993, 471:637-657.
14. Rosdahl H, Hamrin K, Ungerstedt U, Henriksson J. Metabolite levels in human skeletal muscle and adipose tissue studied with microdialysis at low perfusion flow. Am J Physiol 1998, 274:E936-E945.
15. Samuelsson A, Steinvall I, Sjoberg F. Microdialysis shows metabolic effects in skin during fluid resuscitation in burn-injured patients. Crit Care 2006, 10:R172.
16. Schwalbe O, Buerger C, Plock N, Joukhadar C, Kloft C. Urea as an endogenous surrogate in human microdialysis to determine relative recovery of drugs: analytics and applications. J Pharm Biomed Anal 2006, 41:233-239.
17. Setala L, Papp A, Romppanen EL, Mustonen P, Berg L, Harma M. Microdialysis detects postoperative perfusion failure in microvascular flaps. J Reconstr Microsurg 2006, 22:87-96.
18. Stallknecht B, Donsmark M, Enevoldsen LH, Fluckey JD, Galbo H. Estimation of rat muscle blood flow by microdialysis probes perfused with ethanol, [14C]ethanol, and 3H2O. J Appl Physiol 1999, 86:1054-1061.
19. Stallknecht B, Kiens B, Helge JW, Richter EA, Galbo H. Interstitial glycerol concentrations in human skeletal muscle and adipose tissue during graded exercise. Acta Physiol Scand 2004, 180:367-377.
20. Strindberg L, Lonnroth P. Validation of an endogenous reference technique for the calibration of microdialysis catheters. Scand J Clin Lab Invest 2000, 60:205-211.
21. Ungerstedt U. Microdialysis - principles and applications for studies in animals and man. J Intern Med 1991, 230:365-373.
22. Ungerstedt U, Pycock C. Functional correlates of dopamine neurotransmission. Bull Schweiz Akad Med Wiss 1974, 30:44-55.
23. Vespa PM. The implications of cerebral ischemia and metabolic dysfunction for treatment strategies in neurointensive care. Curr Opin Crit Care 2006, 12:119-123.
24. Wilson TE, Monahan KD, Short DS, Ray CA. Effect of age on cutaneous vasoconstrictor responses to norepinephrine in humans. Am J Physiol Regul Integr Comp Physiol 2004, 287:R1230-R1234.