Toxicity and carcinogenicity studies of methylene blue trihydrate in F344N rats and B6C3F1 mice

Food and Chemical Toxicology

Volumn 48, Issue 1, 2010, Pages 169-177

  Auerbach, Scott S ^a   Bristol, Douglas W ^a   Peckham, John C ^a   Travlos, Gregory S ^a   Hébert, Charles D ^b   Chhabra, Rajendra S ^a  

^a NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^b SOUTHERN RESEARCH INSTITUTE   (United States)

Author keywords

Carcinogenicity; Chronic toxicity; Methemoglobin; Methylene blue trihydrate

Indexed keywords

METHYLENE BLUE;

ANEMIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARCINOGENICITY; CONTROLLED STUDY; FEMALE; FISCHER 344 RAT; LYMPHOMA; MALE; MALIGNANT TRANSFORMATION; MOUSE; NONHUMAN; PANCREAS ADENOMA; PANCREAS CARCINOMA; PANCREAS ISLET CELL HYPERPLASIA; PANCREAS ISLET CELL TUMOR; RAT; SMALL INTESTINE CARCINOMA; SURVIVAL RATE;

ANIMALS; BLOOD CELL COUNT; BODY WEIGHT; CARCINOGENICITY TESTS; CARCINOGENS; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HEMATOPOIETIC STEM CELLS; HYPERPLASIA; KAPLAN-MEIERS ESTIMATE; LUNG; MALE; MAMMARY NEOPLASMS, EXPERIMENTAL; METHYLENE BLUE; MICE; MICE, INBRED STRAINS; NEOPLASMS; RATS; RATS, INBRED F344; SEX CHARACTERISTICS; SPECIES SPECIFICITY; SURVIVAL ANALYSIS;

MUS; RATTUS;

EID: 72449209139     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fct.2009.09.034     Document Type: Article

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