A novel chiral resolving reagent, bis((s)-mandelic acid)-3-nitrophthalate, for amlodipine racemate resolution: Scalable synthesis and resolution process

Organic Process Research and Development

Volumn 13, Issue 6, 2009, Pages 1382-1386

  Lee, Hong Woo ^a   Shin, Sung Jae ^a   Yu, Hosung ^a   Kang, Sung Kwon ^a   Yoo, Choong Leol ^a  

^a Chong Kun Dang Research Institute   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 72449207066     PISSN: 10836160     EISSN: 1520586X     Source Type: Journal    
DOI: 10.1021/op900070c     Document Type: Article

References (12)

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12. For each of new chiral resolving reagent in Figure 2, about 20 sets of prescreening were run with the solvents chosen from ICH class 2 or class 3 solvents.