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note
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For intramolecular UCs. we found that the amount of deiodized material could be minimized by the addition of the SM (1 mmol in 25 mL of DMF) via syringe pump (4.1 mL/h) to a suspension of 2.7 equiv of Cu powder in DMF (25 mL) preheated to 115 °C.
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note
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0343965734
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For the preparation and resolution of (R)- and (S)-2-hydroxy-3,3- dimethylbutanoic acid, see: Kontos, Z.; Huszthy, P.; Bradshaw, J. S.; Izatt, R. M. Tetrahedron: Asymmetry 1999, 10, 2087.
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