Long-lasting antinociceptive spinal effects in primates of the novel nociceptin/orphanin FQ receptor agonist UFP-112

Pain

Volumn 148, Issue 1, 2010, Pages 107-113

  Hu, Eric ^a   Calò, Girolamo ^b   Guerrini, Remo ^c   Ko, Mei Chuan ^a,d  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b Neuroscience Center   (Italy)

^c UNIVERSITY OF FERRARA   (Italy)

^d NATIONAL CHENGCHI UNIVERSITY   (Taiwan)

Author keywords

Capsaicin; Morphine; Nociceptin orphanin FQ; NOP receptors; Spinal cord; UFP 112

Indexed keywords

1 (1 CYCLOOCTYLMETHYL 3 HYDROXYMETHYL 4 PIPERIDYL) 3 ETHYL 1,3 DIHYDRO 2H BENZIMIDAZOL 2 ONE; CAPSAICIN; MORPHINE; NALTREXONE; NOCICEPTIN RECEPTOR AGONIST; PHENYLALANYLALPHAAMINOISOBUTYRIC ACID ARGINYLLYSINE; UFP 112; UNCLASSIFIED DRUG;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINOCICEPTION; ARTICLE; CONTROLLED STUDY; DRUG ANTAGONISM; DRUG EFFECT; DRUG MECHANISM; EXPERIMENTAL MONKEY; FEMALE; HYPERALGESIA; MALE; NOCICEPTIVE STIMULATION; NONHUMAN; PRIORITY JOURNAL; PRURITUS; SCRATCHING; SINGLE DRUG DOSE; TREATMENT DURATION; TREATMENT RESPONSE;

ANALGESICS; ANIMALS; BENZIMIDAZOLES; CAPSAICIN; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HYPERALGESIA; INJECTIONS, SPINAL; MACACA MULATTA; MALE; MORPHINE; NALTREXONE; OPIOID PEPTIDES; PAIN MEASUREMENT; PAIN THRESHOLD; PIPERIDINES;

EID: 72449191199     PISSN: 03043959     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pain.2009.10.026     Document Type: Article

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