Investigations on the humidity-induced transformations of salbutamol sulphate particles coated with L-leucine

Pharmaceutical Research

Volumn 25, Issue 10, 2008, Pages 2250-2261

  Raula, Janne ^a   Thielmann, Frank ^b   Kansikas, Jarno ^c   Hietala, Sami ^c   Annala, Minna ^a   Seppälä, Jukka ^a   Lähde, Anna ^a   Kauppinen, Esko I ^a,d  

^a AALTO UNIVERSITY   (Finland)

^b Application Science   (United Kingdom)

^c UNIVERSITY OF HELSINKI   (Finland)

^d VTT TECHNICAL RESEARCH CENTRE OF FINLAND   (Finland)

Author keywords

Crystallization; Humidity; L leucine coating; Salbutamol sulphate; Stability

Indexed keywords

LEUCINE; SALBUTAMOL SULFATE;

ARTICLE; CRYSTALLIZATION; DRUG COATING; DRUG STABILITY; DRUG STRUCTURE; DRUG TRANSFORMATION; HUMIDITY; PARTICLE SIZE; POWDER INHALER; PRIORITY JOURNAL;

ALBUTEROL; BRONCHODILATOR AGENTS; CALORIMETRY, DIFFERENTIAL SCANNING; CHEMISTRY, PHARMACEUTICAL; CRYSTALLIZATION; DRUG STABILITY; HUMIDITY; LEUCINE; MICROSCOPY, ELECTRON, SCANNING; PARTICLE SIZE; POWDERS; RHEOLOGY; TECHNOLOGY, PHARMACEUTICAL; TEMPERATURE; WATER;

EID: 51649108501     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-008-9613-4     Document Type: Article

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50. g drug Powder Technol 167 20 25