The protective effects of Mucuna pruriens seed extract against histopathological changes induced by Malayan cobra (Naja sputatrix) venom in rats

Tropical Biomedicine

Volumn 26, Issue 1, 2009, Pages 80-84

  Fung, S Y ^a   Tan, N H ^a   Liew, S H ^b   Sim, S M ^a   Aguiyi, J C ^c  

^a UNIVERSITY OF MALAYA   (Malaysia)

^b Assunta Hospital   (Malaysia)

^c UNIVERSITY OF JOS   (Nigeria)

Author keywords

[No Author keywords available]

Indexed keywords

PLANT EXTRACT; SNAKE VENOM; VENOM ANTISERUM;

ANIMAL; ARTICLE; CHEMISTRY; DRUG ANTAGONISM; HEART MUSCLE; ISOLATION AND PURIFICATION; LIVER; MALE; PATHOLOGY; PLANT SEED; RAT; SNAKE; SPRAGUE DAWLEY RAT; VELVET BEAN;

ANIMALS; ANTIVENINS; COBRA; COBRA VENOMS; LIVER; MALE; MUCUNA; MYOCARDIUM; PLANT EXTRACTS; RATS; RATS, SPRAGUE-DAWLEY; SEEDS;

EID: 72449175317     PISSN: 01275720     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (7)

1. Aguiyi, J.C., Igweh, A.C., Egesie, U.G. & Leoncini, R. (1999). Studies on possible protection against snake venom using Mucuna pruriens protein immunization. Fitoterapia 70: 21-24.
2. Cher, C.D.N., Armugam, A., Zhu, Y.Z. & Jeyaseelan, K. (2005). Molecular basis of cytotoxicity upon cobra envenomation. Cellular and Molecular Life Sciences 62: 105-118.
3. Guerranti, R., Aguiyi J.C., Errico, E., Pagani, R. & Marinello, E. (2001). Effects of Mucuna pruriens extract on activation of prothrombin by Echis carinatus venom. Journal of Ethanopharmacology 75: 175-180.
4. Guerranti, R., Aguiyi, J.C., Neri, S., Leoncini, R., Pagani, R. & Marinello, E. (2002). Proteins from Mucuna pruriens and enzymes from Echis carinatus venom: Characterization and cross reactions. Journal of Biological Chemistry 277: 17072-17078.
5. Howard-Jones, N.A. (1985). A CIOMS ethicalcode for animal experimentation. WHO Chronicle 39: 51-56.
6. Sim, S.M., Fung, S.Y., Tan, N.H., Marinello, E, Roberto, G. & Aguiyi, J.C. (2006). Effect of pretreatment with Mucuna pruriens seed extract on the pharmacological effects of Naja naja sputatrix (Malayan cobra) venom in rats. Acta Pharmacologica Sinica s1: p326.
7. Tan, N.H. (1991) The Biochemistry of venoms of some venomous snakes of Malaysia - A review. Tropical Biomedicine 8: 91-103.