Effects of Mucuna pruriens extract on activation of prothrombin by Echis carinatus venom

Journal of Ethnopharmacology

Volumn 75, Issue 2-3, 2001, Pages 175-180

  Guerranti, Roberto ^a   Aguiyi, John Chinyere ^b   Errico, Enza ^a   Pagani, Roberto ^a   Marinello, Enrico ^a  

^a UNIVERSITY OF SIENA   (Italy)

^b UNIVERSITY OF JOS   (Nigeria)

Author keywords

Coagulation; Phospholipase A2; Plant extracts; Prothrombin; Snake venom

Indexed keywords

CHROMOGENIC SUBSTRATE; DOPA; MUCUNA PRURIENS EXTRACT; PHOSPHOLIPASE A2; PLANT EXTRACT; PROTEIN; PROTHROMBIN; SNAKE VENOM; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; ASSAY; BLEEDING; BLOOD CLOTTING; CHROMOGENIC ASSAY; CONTROLLED STUDY; MEDICINAL PLANT; MOUSE; NONHUMAN; PARKINSON DISEASE; PLANT; PLANT SEED; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTECTION; TRADITIONAL MEDICINE; VELVET BEAN;

ANIMALS; ANTIVENINS; ELECTROPHORESIS, POLYACRYLAMIDE GEL; MICE; MICE, INBRED ICR; PLANT EXTRACTS; PROTHROMBIN; ROSALES; VIPER VENOMS;

EID: 0035070378     PISSN: 03788741     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-8741(00)00401-3     Document Type: Article

References (23)

1. Mechanism of action of the aqueous seed extract of Mucuna pruriens on the guinea pig ileum
2. Studies on possible protection against snake venom using Mucuna pruriens protein immunization
3. Antidiabetic evaluation of Mucuna pruriens, Linn seeds
4. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
5. Venoms, antivenoms and immunotherapy
6. Alkaloids of Mucuna pruriens: chemistry and pharmacology
7. Characterization of the factor responsible for the antisnake activity of Mucuna pruriens seeds
8. Analgesic and antipyretic effects of Mucuna pruriens
9. 2 from Indian saw-scaled viper (Echis carinatus) venom: characterization of antigenic, catalytic and pharmacological properties
10. 2 from Indian saw-scaled viper (Echis carinatus)
11. 2 from Naja nigricollis venom binds to coagulation factor Xa to inhibit the Prothrominase complex
12. 2
13. 2
14. Cleavage of structural proteins during the assembly of the head of bacteriophage T4
15. An alternative medicine treatment for Parkinson's disease: results of a multicenter clinical trial. HP-200 in Parkinson's Disease Study Group
16. Isolation and characterization of a forssman antigen-binding lectin from velvet bean (mucuna derringiana) seeds
17. Purification and properties of prothrombin activator from the venom of Echis carinatus
18. 2 from Echis carinatus (saw-scaled viper)
19. cDNA cloning and deduced amino acid sequence of prothrombin activator (Ecarin) from Kenian Echis carinatus venom
20. 2: purification, characterization and computer modelling of an enzymically active Ser-49 phospholipase A2
21. The relationship between enzymatic activity and pharmacological properties of phospholipases in natural poisons
22. Clinical features of envenoming of snake bites
23. Isolation and characterization of carinactivase, a novel prothrombin activator in Echis carinatus venom with a unique catalytic mechanism