-
2
-
-
0030745855
-
-
(a) Han, Y.; Liao, S.; Qui, W.; Cai, C.; Hruby, V. J. Tetrahedron Lett. 1997, 38, 5135.
-
(1997)
Tetrahedron Lett.
, vol.38
, pp. 5135
-
-
Han, Y.1
Liao, S.2
Qui, W.3
Cai, C.4
Hruby, V.J.5
-
3
-
-
0030605167
-
-
(b) Liao, S.; Han, Y.; Qui, W.; Bruck, M.; Hruby, V. J. Tetrahedron Lett. 1996, 37, 7917.
-
(1996)
Tetrahedron Lett.
, vol.37
, pp. 7917
-
-
Liao, S.1
Han, Y.2
Qui, W.3
Bruck, M.4
Hruby, V.J.5
-
4
-
-
0002432346
-
-
Yamazaki, T.; Shinohara, N.; Kitazume, T.; Sato, S. J. Fluorine Chem. 1999, 97, 91.
-
(1999)
J. Fluorine Chem.
, vol.97
, pp. 91
-
-
Yamazaki, T.1
Shinohara, N.2
Kitazume, T.3
Sato, S.4
-
6
-
-
0026572606
-
-
(a) Schmidt, U.; Griesser, H.; Leitenberger, V.; Lieberknecht, A.; Mangold, R.; Meyer, R.; Riedl, B. Synthesis 1992, 487.
-
(1992)
Synthesis
, pp. 487
-
-
Schmidt, U.1
Griesser, H.2
Leitenberger, V.3
Lieberknecht, A.4
Mangold, R.5
Meyer, R.6
Riedl, B.7
-
7
-
-
1542741069
-
-
(b) Su, G.; Pan, C.; Wang, H.; Zeng, L. Synth. Commun. 2004, 34, 665.
-
(2004)
Synth. Commun.
, vol.34
, pp. 665
-
-
Su, G.1
Pan, C.2
Wang, H.3
Zeng, L.4
-
8
-
-
33751500661
-
-
Meanwell, N. A.; Roth, H. R.; Smith, E. C. R.; Wedding, D. L.; Wright, J. J. K. J. Org. Chem. 1991, 56, 6897.
-
(1991)
J. Org. Chem.
, vol.56
, pp. 6897
-
-
Meanwell, N.A.1
Roth, H.R.2
Smith, E.C.R.3
Wedding, D.L.4
Wright, J.J.K.5
-
9
-
-
0036001123
-
-
(a) Konkel, J. T.; Fan, J.; Jayachandran, B.; Kirk, K. L. J. Fluorine Chem. 2002, 115, 27.
-
(2002)
J. Fluorine Chem.
, vol.115
, pp. 27
-
-
Konkel, J.T.1
Fan, J.2
Jayachandran, B.3
Kirk, K.L.4
-
10
-
-
0023873335
-
-
(b) Kolycheva, M. T.; Yagupol'skii, Yu., L.; Zaitsev, L. M.; Gerus, I. J.; Kukhar', V. P.; Klebanov, B. M. Khim.-Farm. Zh. 1988, 22, 159.
-
(1988)
Khim.-farm. Zh.
, vol.22
, pp. 159
-
-
Kolycheva, M.T.1
Yagupol'skii, Yu.L.2
Zaitsev, L.M.3
Gerus, I.J.4
Kukhar, V.P.5
Klebanov, B.M.6
-
11
-
-
18544409605
-
-
(a) Alias, M.; Lopez, M. P.; Cativiela, C. Tetrahedron 2004, 60, 885.
-
(2004)
Tetrahedron
, vol.60
, pp. 885
-
-
Alias, M.1
Lopez, M.P.2
Cativiela, C.3
-
12
-
-
23844511897
-
-
(b) Schmidt, T.; Baumann, W.; Drexler, H.-J.; Arrieta, A.; Heller, D. Organometallics 2005, 24, 3842.
-
(2005)
Organometallics
, vol.24
, pp. 3842
-
-
Schmidt, T.1
Baumann, W.2
Drexler, H.-J.3
Arrieta, A.4
Heller, D.5
-
13
-
-
1842607456
-
-
(a) Roff, G. J.; Lloyd, R. C.; Turner, N. J. J. Am. Chem. Soc. 2004, 126, 4098.
-
(2004)
J. Am. Chem. Soc.
, vol.126
, pp. 4098
-
-
Roff, G.J.1
Lloyd, R.C.2
Turner, N.J.3
-
14
-
-
0142094000
-
-
(b) Enright, A.; Alexandre, F.-R.; Roff, G.; Fotheringham, I. G.; Dawson, M. J.; Turner, N. J. Chem. Commun. 2003, 2636.
-
(2003)
Chem. Commun.
, pp. 2636
-
-
Enright, A.1
Alexandre, F.-R.2
Roff, G.3
Fotheringham, I.G.4
Dawson, M.J.5
Turner, N.J.6
-
15
-
-
0037148008
-
-
(c) Alexandre, F.-R.; Pantaleone, D. P.; Taylor, P. P.; Fotheringham, I. G.; Ager, D. J.; Turner, N. J. Tetrahedron Lett. 2002, 43, 707.
-
(2002)
Tetrahedron Lett.
, vol.43
, pp. 707
-
-
Alexandre, F.-R.1
Pantaleone, D.P.2
Taylor, P.P.3
Fotheringham, I.G.4
Ager, D.J.5
Turner, N.J.6
-
17
-
-
11144231136
-
-
(a) Kimura, M.; Yamazaki, T.; Kitazume, T.; Kubota, T. Org. Lett. 2004, 6, 4651.
-
(2004)
Org. Lett.
, vol.6
, pp. 4651
-
-
Kimura, M.1
Yamazaki, T.2
Kitazume, T.3
Kubota, T.4
-
18
-
-
0026737513
-
-
(b) Eguchi, T.; Aoyama, T.; Kakinuma, K. Tetrahedron Lett. 1992, 38, 5545.
-
(1992)
Tetrahedron Lett.
, vol.38
, pp. 5545
-
-
Eguchi, T.1
Aoyama, T.2
Kakinuma, K.3
-
19
-
-
0041589245
-
-
(c) Pinna, G. A.; Cignarella, G.; Ruiu, S.; Loriga, G.; Murineddu, G.; Villa, S.; Grella, G. E.; Cossu, G.; Fratta, W. Bioorg. Med. Chem. 2003, 11, 4015.
-
(2003)
Bioorg. Med. Chem.
, vol.11
, pp. 4015
-
-
Pinna, G.A.1
Cignarella, G.2
Ruiu, S.3
Loriga, G.4
Murineddu, G.5
Villa, S.6
Grella, G.E.7
Cossu, G.8
Fratta, W.9
-
20
-
-
0027488908
-
-
(d) Carceller, E.; Merlos, M.; Giral, M.; Almansa, C.; Bartoli, J.; Garcia-Rafanell, J.; Forn, J. J. Med. Chem. 1993, 36, 2984.
-
(1993)
J. Med. Chem.
, vol.36
, pp. 2984
-
-
Carceller, E.1
Merlos, M.2
Giral, M.3
Almansa, C.4
Bartoli, J.5
Garcia-Rafanell, J.6
Forn, J.7
-
21
-
-
0030862913
-
-
For a reported example of predominant formation of Z-isomer, see: (e) Ohno, N.; Fukamiya, N.; Okano, M.; Tagahara, K.; Lee, K.-H. Bioorg. Med. Chem. 1997, 5, 1489.
-
(1997)
Bioorg. Med. Chem.
, vol.5
, pp. 1489
-
-
Ohno, N.1
Fukamiya, N.2
Okano, M.3
Tagahara, K.4
Lee, K.-H.5
-
22
-
-
72449130199
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note
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Interestingly, examination of experimental details in various reports of HWE olefination of phenyl trifluoromethyl ketone in THF or toluene using NaH as a base might suggest an opposite hold-time/selectivity relationship.
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23
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72449133548
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note
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Walphos 8-1: (R)-1-[(R)-2-(22 -dicyclohexylphosphinophenyl-)ferrocenyl] ethyldi(bis-(3,5-trifluoromethyl)phenyl)phosphine, available from Solvias, SL-W008-1; nbd: norbornadiene.
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-
-
24
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0000744779
-
-
(a) Evans, D. A.; Britton, T. C.; Dorow, R. L.; Dellaria, J. F. Tetrahedron 1988, 44, 5525.
-
(1988)
Tetrahedron
, vol.44
, pp. 5525
-
-
Evans, D.A.1
Britton, T.C.2
Dorow, R.L.3
Dellaria, J.F.4
-
26
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20744436699
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Anti-diastereomer formation with up to 80% de was reported for a similar substrate with electron-rich aryl substituent and BnBr as an electrophile; 62% de and low conversion was reported for Nelectrophile. Tamura, K.; Yamazaki, T.; Kitazume, T.; Kubota, T. J. Fluorine Chem. 2005, 126, 918.
-
(2005)
J. Fluorine Chem.
, vol.126
, pp. 918
-
-
Tamura, K.1
Yamazaki, T.2
Kitazume, T.3
Kubota, T.4
-
27
-
-
72449181575
-
Production of pure chiral amino alcohol intermediates, derivatives thereof, and uses thereof
-
U.S. Patent Publ. Appl. US 2007/249869, 2007
-
(a) Sellstedt, J.; Cheal, G.; Noureldin, R.; Chan, A.W.-Y.; Raveendranath, P.; Caggiano, T. J. Production of Pure Chiral Amino Alcohol Intermediates, Derivatives Thereof, and Uses Thereof. U.S. Patent Publ. Appl. US 2007/249869, 2007; Chem. Abstr. 2007, 147, 486150.
-
(2007)
Chem. Abstr.
, vol.147
, pp. 486150
-
-
Sellstedt, J.1
Cheal, G.2
Noureldin, R.3
Chan, A.W.-Y.4
Raveendranath, P.5
Caggiano, T.J.6
-
28
-
-
0033435122
-
-
(b) Prashad, M.; Liu, Y.; Kim, H.-Y.; Repic, O.; Blacklock, T. J. Tetrahedron: Asymmetry 1999, 10, 3479.
-
(1999)
Tetrahedron: Asymmetry
, vol.10
, pp. 3479
-
-
Prashad, M.1
Liu, Y.2
Kim, H.-Y.3
Repic, O.4
Blacklock, T.J.5
-
29
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72449164193
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note
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Once again, the (R)-enantiomer of benzyloxazolidinone chiral auxiliary needed for introduction of (S)-stereocenter at the β-position that way would not generate the required diastereomer after α-azidation.
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31
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72449161836
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note
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In a typical run, 4-5 HPLC area % of 18 was formed, with 2.1% remaining after crystallization.
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-
-
32
-
-
0025324609
-
-
Evans, D. A.; Britton, T. C.; Ellman, J. A.; Dorow, R. L. J. Am. Chem. Soc. 1990, 112, 4011.
-
(1990)
J. Am. Chem. Soc.
, vol.112
, pp. 4011
-
-
Evans, D.A.1
Britton, T.C.2
Ellman, J.A.3
Dorow, R.L.4
-
33
-
-
43949160561
-
-
For triisopropylsulfonyl azide stability data, see: Tuma, L. D. Thermochim. Acta 1994, 243, 161.
-
(1994)
Thermochim. Acta
, vol.243
, pp. 161
-
-
Tuma, L.D.1
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