Parity and the risk of breast and ovarian cancer in BRCA1 and BRCA2 mutation carriers

Breast Cancer Research and Treatment

Volumn 119, Issue 1, 2010, Pages 221-232

  Milne, Roger L ^a   Osorio, Ana ^a   Ramón Y Cajal, Teresa ^b   Baiget, Montserrat ^b   Lasa, Adriana ^b   Diaz Rubio, Eduardo ^c   De La Hoya, Miguel ^c   Caldés, Trinidad ^c   Teulé, Alex ^d   Lázaro, Conxi ^d   Blanco, Ignacio ^d   Balmaña, Judith ^e   Sánchez Ollé, Gessamí ^e   Vega, Ana ^f   Blanco, Ana ^f   Chirivella, Isabel ^g,h   Esteban Cardeñosa, Eva ^h,i   Durán, Mercedes ^j   Velasco, Eladio ^j   Martínez De Dueñas, Eduardo ^h,k   Tejada, María Isabel ^l   Miramar, María Dolores ^m   Calvo, María Teresa ^m   Guillén Ponce, Carmen ^h,n   Salazar, Raquel ^o   San Román, Carlos ^p   Urioste, Miguel ^a,q   Benítez, Javier ^a,q   more..

^a Centro Nacional de Investigaciones Oncológicas   (Spain)

^b HOSPITAL DE LA SANTA CREU I SANT PAU   (Spain)

^c HOSPITAL CLÍNICO SAN CARLOS   (Spain)

^d CATALAN INSTITUTE OF ONCOLOGY   (Spain)

^e HOSPITAL UNIVERSITARI VALL D HEBRON   (Spain)

^f UNIVERSITY OF SANTIAGO DE COMPOSTELA   (Spain)

^g UNIVERSITY OF VALENCIA   (Spain)

^h Grupo de Cáncer Hereditario de la Comunidad Valenciana   (Spain)

ⁱ HOSPITAL UNIVERSITARIO LA FE   (Spain)

^j Universidad de Valladolid y Consejo Superior de Investigaciones Científicas   (Spain)

^k Instituto Oncológico Consorcio Hospitalario Provincial de Castellón   (Spain)

^l HOSPITAL DE CRUCES   (Spain)

^m HOSPITAL UNIVERSITARIO MIGUEL SERVET   (Spain)

ⁿ HOSPITAL GENERAL UNIVERSITARIO DE ELCHE   (Spain)

^o Centro de Investigacion del Cancer   (Spain)

^p HOSPITAL RAMÓN Y CAJAL   (Spain)

^q CENTRO DE INVESTIGACIÓN BIOMÉDICA EN RED DE ENFERMEDADES RARAS CIBERER   (Spain)

more..

Author keywords

BRCA1; BRCA2; Breast cancer; Ovarian cancer; Parity

Indexed keywords

BRCA1 PROTEIN; BRCA2 PROTEIN;

ADULT; AGED; ARTICLE; BRCA2 GENE; BREAST CANCER; CANCER RISK; FEMALE; GENE MUTATION; GENETIC ASSOCIATION; HAZARD RATIO; HETEROZYGOTE; HUMAN; LIVE BIRTH; MAJOR CLINICAL STUDY; ONCOGENE; OVARY CANCER; PARITY; POPULATION; PRIORITY JOURNAL; PROPORTIONAL HAZARDS MODEL;

ADOLESCENT; ADULT; AGED; BREAST NEOPLASMS; DNA MUTATIONAL ANALYSIS; FEMALE; GENES, BRCA1; GENES, BRCA2; HETEROZYGOTE; HUMANS; MATERNAL AGE; MIDDLE AGED; MUTATION; OVARIAN NEOPLASMS; PARITY; PREGNANCY; RISK;

EID: 72449127102     PISSN: 01676806     EISSN: 15737217     Source Type: Journal    
DOI: 10.1007/s10549-009-0394-1     Document Type: Article

References (28)

1. A Antoniou PD Pharoah S Narod, et al. 2003 Average risks of breast and ovarian cancer associated with BRCA1 or BRCA2 mutations detected in case series unselected for family history: a combined analysis of 22 studies Am J Hum Genet 72 5 1117 1130 10.1086/375033 10.1086/375033 1:CAS:528:DC%2BD3sXjslagtbg%3D 12677558 (Pubitemid 36530000)
2. D Goldgar V Venne T Conner, et al. 2007 BRCA phenocopies or ascertainment bias? J Med Genet 44 8 e86 17673440 (author reply e88)
3. J Gronwald C Cybulski J Lubinski, et al. 2007 Phenocopies in breast cancer 1 (BRCA1) families: implications for genetic counselling J Med Genet 44 4 e76 10.1136/jmg.2006.048462 10.1136/jmg.2006.048462 17400795
4. A Smith A Moran MC Boyd, et al. 2007 Phenocopies in BRCA1 and BRCA2 families: evidence for modifier genes and implications for screening J Med Genet 44 1 10 15 10.1136/jmg.2006.043091 10.1136/jmg.2006.043091 1:CAS:528: DC%2BD2sXhvVGisro%3D 17079251 (Pubitemid 46142833)
5. RL Milne A Osorio T Ramón y Cajal, et al. 2008 The average cumulative risks of breast and ovarian cancer for carriers of mutations in BRCA1 and BRCA2 attending genetic counselling units in Spain Clin Cancer Res 14 9 2861 2869 10.1158/1078-0432.CCR-07-4436 10.1158/1078-0432.CCR-07-4436 1:CAS:528:DC%2BD1cXlsFSjs7g%3D 18451254
6. L Tryggvadottir H Sigvaldason GH Olafsdottir, et al. 2006 Population-based study of changing breast cancer risk in Icelandic BRCA2 mutation carriers, 1920-2000 J Natl Cancer Inst 98 2 116 122 1:CAS:528:DC%2BD28Xmsl2rsg%3D%3D 16418514
7. MC King JH Marks JB Mandell 2003 Breast and ovarian cancer risks due to inherited mutations in BRCA1 and BRCA2 Science 302 5645 643 646 10.1126/science.1088759 10.1126/science.1088759 1:CAS:528:DC%2BD3sXotlWqt7Y%3D 14576434 (Pubitemid 37310920)
8. S Narod H Lynch T Conway, et al. 1993 Increasing incidence of breast cancer in family with BRCA1 mutation Lancet 341 8852 1101 1102 10.1016/0140-6736(93)92468-9 10.1016/0140-6736(93)92468-9 1:STN:280: DyaK3s3isFOmug%3D%3D 8097005
9. JL Kelsey MD Gammon EM John 1993 Reproductive factors and breast cancer Epidemiol Rev 15 1 36 47 1:STN:280:DyaK2c%2FgvFCisQ%3D%3D 8405211
10. K Elmasry SA Gayther 2006 Ovarian cancer aetiology: facts and fiction J Fam Plan Reprod Health Care 32 2 82 86 10.1783/147118906776276297 10.1783/147118906776276297
11. Milne R, Chenevix-Trench G (2007) Breast cancer risk modifiers. In: Isaacs C, Rebbeck TR (eds) Hereditary breast cancer, 1st edn. Informa Healthcare, New York
12. Collaborative Group on Hormonal Factors in Breast Cancer 2002 Breast cancer and breastfeeding: collaborative reanalysis of individual data from 47 epidemiological studies in 30 countries, including 50302 women with breast cancer and 96973 women without the disease Lancet 360 9328 187 195 10.1016/S0140-6736(02)09454-0 10.1016/S0140-6736(02)09454-0 (Pubitemid 34804645)
13. AS Whittemore R Harris J Itnyre 1992 Characteristics relating to ovarian cancer risk: collaborative analysis of 12 US case-control studies. II. Invasive epithelial ovarian cancers in white women. Collaborative ovarian cancer group Am J Epidemiol 136 10 1184 1203 1:STN:280:DyaK3s7hvVKgsQ%3D%3D 1476141 (Pubitemid 23026890)
14. CA Cullinane J Lubinski SL Neuhausen, et al. 2005 Effect of pregnancy as a risk factor for breast cancer in BRCA1/BRCA2 mutation carriers Int J Cancer 117 6 988 991 10.1002/ijc.21273 10.1002/ijc.21273 1:CAS:528:DC%2BD2MXht1CntLfJ 15986445 (Pubitemid 41688574)
15. J Gronwald T Byrski T Huzarski, et al. 2006 Influence of selected lifestyle factors on breast and ovarian cancer risk in BRCA1 mutation carriers from Poland Breast Cancer Res Treat 95 2 105 109 10.1007/s10549-005-9051-5 10.1007/s10549-005-9051-5 16261399
16. H Jernstrom C Lerman P Ghadirian, et al. 1999 Pregnancy and risk of early breast cancer in carriers of BRCA1 and BRCA2 Lancet 354 9193 1846 1850 10.1016/S0140-6736(99)04336-6 10.1016/S0140-6736(99)04336-6 1:STN:280: DC%2BD3c%2FkvFCitw%3D%3D 10584720
17. N Andrieu DE Goldgar DF Easton, et al. 2006 Pregnancies, breast-feeding, and breast cancer risk in the international BRCA1/2 carrier cohort study (IBCCS) J Natl Cancer Inst 98 8 535 544 16622123
18. AC Antoniou A Shenton ER Maher, et al. 2006 Parity and breast cancer risk among BRCA1 and BRCA2 mutation carriers Breast Cancer Res 8 6 R72 10.1186/bcr1630 10.1186/bcr1630 17187672 (Pubitemid 350201709)
19. J Kotsopoulos J Lubinski HT Lynch, et al. 2007 Age at first birth and the risk of breast cancer in BRCA1 and BRCA2 mutation carriers Breast Cancer Res Treat 105 2 221 228 10.1007/s10549-006-9441-3 10.1007/s10549-006-9441-3 17245541 (Pubitemid 47366879)
20. TR Rebbeck Y Wang PW Kantoff, et al. 2001 Modification of BRCA1- and BRCA2-associated breast cancer risk by AIB1 genotype and reproductive history Cancer Res 61 14 5420 5424 1:CAS:528:DC%2BD3MXlsVChs7g%3D 11454686
21. JR McLaughlin HA Risch J Lubinski, et al. 2007 Reproductive risk factors for ovarian cancer in carriers of BRCA1 or BRCA2 mutations: a case-control study Lancet Oncol 8 1 26 34 10.1016/S1470-2045(06)70983-4 10.1016/S1470-2045(06) 70983-4 1:CAS:528:DC%2BD2sXhsFGmuw%3D%3D 17196508 (Pubitemid 46001033)
22. AC Antoniou M Rookus N Andrieu, et al. 2009 Reproductive and hormonal factors, and ovarian cancer risk for BRCA1 and BRCA2 mutation carriers: results from the International BRCA1/2 carrier cohort study Cancer Epidemiol Biomarkers Prev 18 2 601 610 10.1158/1055-9965.EPI-08-0546 10.1158/1055-9965.EPI-08-0546 1:CAS:528:DC%2BD1MXhslShu7k%3D 19190154
23. AC Antoniou DE Goldgar N Andrieu, et al. 2005 A weighted cohort approach for analysing factors modifying disease risks in carriers of high-risk susceptibility genes Genet Epidemiol 29 1 1 11 10.1002/gepi.20074 10.1002/gepi.20074 15880399 (Pubitemid 40911295)
24. StataCorp (2007) Stata Statistical Software: Release 10. StataCorp LP, College Station, TX, USA
25. HO Adami CC Hsieh M Lambe, et al. 1994 Parity, age at first childbirth, and risk of ovarian cancer Lancet 344 8932 1250 1254 10.1016/S0140-6736(94) 90749-8 10.1016/S0140-6736(94)90749-8 1:STN:280:DyaK2M%2FlslGmug%3D%3D 7967985 (Pubitemid 24334680)
26. T Riman PW Dickman S Nilsson, et al. 2002 Risk factors for invasive epithelial ovarian cancer: results from a Swedish case-control study Am J Epidemiol 156 4 363 373 10.1093/aje/kwf048 10.1093/aje/kwf048 12181107 (Pubitemid 34858005)
27. M Booth V Beral P Smith 1989 Risk factors for ovarian cancer: a case-control study Br J Cancer 60 4 592 598 1:STN:280:DyaK3c%2FivVSgtA%3D%3D 2679848
28. A Polychronopoulou A Tzonou CC Hsieh, et al. 1993 Reproductive variables, tobacco, ethanol, coffee and somatometry as risk factors for ovarian cancer Int J Cancer 55 3 402 407 10.1002/ijc.2910550312 10.1002/ijc.2910550312 1:STN:280:DyaK3szovVSitw%3D%3D 8375923 (Pubitemid 23300588)