Significance of high density lipoprotein-cholesterol in cardiovascular risk prevention: Recommendations of HDL Forum

American Journal of Cardiovascular Drugs

Volumn 4, Issue 5, 2004, Pages 299-314

  Ascaso, Juan F ^a   Fernández Cruz, Arturo ^b   González Santos, Pedro ^c   Hernández Mijares, Antonio ^d   Mangas Rojas, Alipio ^e   Millán, Jesús ^f   Pallardo, Luis Felipe ^g   Pedro Botet, Juan ^h   Pérez Jiménez, Francisco ⁱ   Pía, Gonzalo ^j   Pintó, Xavier ^k   Plaza, Ignacio ^g   Rubiés Prat, Juan ^h  

^a HOSPITAL CLÍNICO UNIVERSITARIO   (Spain)

^b UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

^c HOSPITAL UNIVERSITARIO VIRGEN DE LA VICTORIA   (Spain)

^d HOSPITAL UNIVERSITARIO DR PESET   (Spain)

^e HOSPITAL UNIVERSITARIO PUERTA DEL MAR   (Spain)

^f HOSPITAL GENERAL UNIVERSITARIO GREGORIO MARAÑÓN   (Spain)

^g HOSPITAL UNIVERSITARIO LA PAZ   (Spain)

^h UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

ⁱ HOSPITAL UNIVERSITARIO REINA SOFÍA   (Spain)

^j Internal Medicine Service   (Spain)

^k HOSPITAL UNIVERSITARI DE BELLVITGE   (Spain)

more..

Author keywords

[No Author keywords available]

Indexed keywords

BEZAFIBRATE; FENOFIBRATE; FIBRIC ACID DERIVATIVE; GEMFIBROZIL; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; LOW DENSITY LIPOPROTEIN CHOLESTEROL; NICOTINIC ACID; PRAVASTATIN; SIMVASTATIN;

CARDIOVASCULAR RISK; CHOLESTEROL BLOOD LEVEL; CLINICAL TRIAL; DISEASE ASSOCIATION; DISEASE EXACERBATION; DRUG EFFICACY; DRUG MECHANISM; DRUG TARGETING; DYSLIPIDEMIA; EXERCISE; FLUSHING; HUMAN; HYPERCHOLESTEROLEMIA; HYPERPIGMENTATION; HYPERTRIGLYCERIDEMIA; ISCHEMIC HEART DISEASE; LIFESTYLE; METABOLIC SYNDROME X; NON INSULIN DEPENDENT DIABETES MELLITUS; PEPTIC ULCER; PRIMARY PREVENTION; PRIORITY JOURNAL; RETROSPECTIVE STUDY; REVIEW; SECONDARY PREVENTION; SIDE EFFECT; SMOKING CESSATION; SUSTAINED RELEASE FORMULATION; WEIGHT REDUCTION;

ANTILIPEMIC AGENTS; BEZAFIBRATE; CARDIOVASCULAR DISEASES; CHOLESTEROL; CHOLESTEROL, HDL; GEMFIBROZIL; HUMANS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; HYPERLIPIDEMIAS; NIACIN; PROCETOFEN; RISK ASSESSMENT;

EID: 7244251733     PISSN: 11753277     EISSN: None     Source Type: Journal    
DOI: 10.2165/00129784-200404050-00003     Document Type: Review

References (96)

1. Goldberg IJ. Diabetic dyslipidemia: causes and consequences. J Clin Endocrinol Metab 2001; 86: 965-71
2. Stein O, Stein Y. Atheroprotective mechanisms of HDL. Atherosclerosis 1999; 144: 285-301
3. Badimon JJ, Badimon L, Fuster V. Regression of atherosclerosis lesions by HDL plasma fraction in the cholesterol-fed rabbit. J Clin Invest 1990; 85: 1234-41
4. Ginsberg HN. Lipoprotein physiology. Endocrinol Metab Clin North Am 1998; 27: 503-19
5. Nissen SE, Tsunoda T, Murat Tuzcu E, et al. Effect of recombinant apoA-I milano on coronary atherosclerosis in patients with acute coronary syndromes: a randomized controlled trial. JAMA 2003; 290: 2292-300
6. National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). Executive summary of the third report of the National Cholesterol Education Program (NCEP). JAMA 2001; 285: 2486-97
7. De Backer G, Ambrosioni E, Borch-Johnsen K, et al. European guidelines on cardiovascular disease prevention in clinical practice: Third Joint Task Force of European and Other Societies on Cardiovascular Disease Prevention in Clinical Practice. Eur Heart J 2003; 24: 1601-10
8. Austin MA, Hokanson JE, Edwards KL. Hypertrigliceridemia as a cardiovascular risk factor. Am J Cardiol 1998; 81 (4 Suppl.): 7B-12B
9. Grundy SM. Low density lipoprotein, non-high density lipoprotein and apolipoprotein B as a targets of lipid-lowering therapy. Circulation 2002; 106: 2526-9
10. Sacks FM. The role of high density lipoprotein (HDL) cholesterol in the prevention and treatment of coronary heart disease: Expert Group recommendations. The Expert Group on HDL Cholesterol. Am J Cardiol 2002; 90: 139-43
11. Salonen JT, Salonen R, Seppanen K, et al. HDL, HDL2 and HDL3 subfractions and the risk of acute myocardial infarction: a prospective population study in eastern Finnish men. Circulation 1991; 84: 129-39
12. Assmann G, Schulte H, von Eckardstein A, et al. High density lipoprotein cholesterol as a predictor of coronary heart disease risk: the PROCAM experience and pathophysiological implications for reverse cholesterol transport. Atherosclerosis 1996; 124 Suppl.: S11-20
13. Durrington P. Hyperlipidaemia: diagnosis and management. Oxford: Butterworth and Heinemann, 1995: 82
14. Corti MC, Guralnik JM, Salive ME, et al. HDL cholesterol predicts coronary heart disease mortality in older persons. JAMA 1995; 274: 539-44
15. Lu W, Resnick HE, Jablonski KA, et al. Non-HDL cholesterol as a predictor of cardiovascular disease in type 2 diabetes: the Strong Heart Study. Diabetes Care 2003; 26: 16-23
16. Gordon DJ, Probstfield JL, Garrison JR, et al. High density lipoprotein cholesterol and cardiovascular disease: four prospective American studies. Circulation 1989; 79: 8-15
17. Plaza I, Mariscal RP, Muõz MT, et al. Estudio de Fuenlabrada: asociación entre los niveles de lípidos y lipoproteínas en niños y adolescentes con la prevalencia de cardiopatía isquémica en sus familiares. Rev Esp Cardiol 1990; 43: 212-8
18. Ministerio de Sanidad y Consumo. Control de la colesterolemia en España 2000: un instrumento para la prevención cardiovascular. Madrid: Ministerio de Sanidad y Consumo, 2000
19. Castelli WP, Garrison RJ, Wilson W, et al. Incidence of coronary heart disease and lipoprotein cholesterol levels: the Framingham study. JAMA 1986; 256: 2835-8
20. Pekkanen J, Linn S, Heiss G, et al. Ten year mortality from cardiovascular disease in relation to cholesterol level among men with and without preexisting cardiovascular disease. N Engl J Med 1990; 322: 1700-7
21. Grover SA, Palmer CS, Coupall L. Serum lipid screening to identify high risk individuals for coronary death: the results of the Lipid Research Clinics prevalence cohort. Arch Intern Med 1994; 154: 679-84
22. Diabetes Atherosclerosis Intervention Study Investigators. Effect of fenofibrate on progression of coronary-artery disease in type 2 diabetes: the Diabetes Atherosclerosis Intervention Study, a randomised study. Lancet 2001; 357: 905-10
23. Ericsson CG, Nilsson J, Grip L, et al. Effect of bezafibrate over five years on coronary plaques causing 20% to 50% diameter narrowing. The Bezafibrate Coronary Atherosclerosis Intervention Trial (BECAIT). Am J Cardiol 1997; 80: 1125-9
24. Frick MH, Syvänne M, Nieminen MS, et al. Prevention of the angiographic progression of coronary and vein-graft atherosclerosis by gemfibrozil after coronary bypass surgery in men with low levels of HDL cholesterol: the Lopid Coronary Angiography Trial (LOCAT) Study Group. Circulation 1997; 96: 2137-43
25. Rubins HB, Robins SJ, Collins D, et al. Gemfibrozil for the secondary prevention of coronary heart disease in men with low levels of high density lipoprotein cholesterol: the Veterans Affairs High Density Lipoprotein Cholesterol Intervention Trial Study Group. N Engl J Med 1999; 341: 410-8
26. Wannamethee SG, Shaper AG, Ebrahim S. HDL-Cholesterol, total cholesterol, and the risk of stroke in middle-aged British men. Stroke 2000; 31: 1882-8
27. Reaven G. Metabolic syndrome: pathophysiology and implications for management of cardiovascular disease. Circulation 2002; 106: 286-8
28. Balkau B, Charles MA. Comment on the provisional report from the WHO consultation: the European Group for the Study of Insulin Resistance (EGIR). Diabetic Medicine 1999; 16: 442-3
29. Zimmet P, Alberti KGMM, Shaw J. Global and societal implications of the diabetes epidemic. Nature 2001; 414: 782-7
30. Isomaa B, Algrem P, Tuomi T. Cardiovascular morbidity and mortality associated with the metabolic syndrome. Diabetes Care 2001; 24: 683-9
31. Lakka HM, Laaksonen DE, Lakka TA, et al. The metabolic syndrome and total and cardiovascular disease mortality in middle-aged men. JAMA 2002; 288: 2709-16
32. Heinchen OP, Frick MH. Coronary heart disease incidence in NIDDM patients in the Helsinki Heart Study. Diabetes Care 1992; 15: 820-5
33. Downs JR, Clearfield M, Weiss S, et al. Primary prevention of acute coronary events with lovastatin in men and women with average cholesterol levels. JAMA 1998; 279: 1615-22
34. Elkeles RS, Diamond JR, Poulter C, et al. Cardiovascular outcomes in type 2 diabetes. Diabetes Care 1998; 21: 641-8
35. Pyörala K, Pedersen TR, Kjekshus J, et al. The Scandinavian Simvastatin Survival Study (4S) Group. Cholesterol lowering with simvastatin improves prognosis of diabetic patients with coronary heart disease. Diabetes Care 1997; 20: 614-20
36. The Long-term Intervention with Pravastatin in Ischaemic Disease (LIPID) Study Group. Prevention of cardiovascular events and death with pravastatin in patients with coronary heart disease and a broad range of initial cholesterol levels. N Engl J Med 1998; 339: 1349-57
37. Goldberg RB, Mellies MJ, Sacks FM, et al. Cardiovascular events and their reduction with pravastatin in diabetic and glucose intolerant myocardial infarction survivors with average cholesterol levels: subgroup analyses in the Cholesterol and Recurrent Events (CARE) trial. Circulation 1998; 98: 2513-9
38. Heart Protection Study Collaborative Group. MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20536 high risk individuals: a randomised placebo-controlled trial. Lancet 2002; 360: 7-22
39. Goldbourt U, Yaari S, Medalie JH. Isolated low HDL cholesterol as a risk factor for coronary heart disease mortality: a 21-year follow-up of 8000 men. Arterioscler Thromb Vasc Biol 1997; 17: 107-13
40. Alberti KGMM, Zimmet PZ. Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: Diagnosis and classification of diabetes mellitus, provisional report of a WHO consultation. Diabet Med 1998; 15: 539-53
41. González-Santos P, Abarca M, Aguado F, et al. Hiperlipidemia y enfermedad coronaria en la diabetes mellitus no insulinodependiente (DMNID). In: de Oya M, Garcés C, editors. Metabolismo Lipídico. Madrid: IDEPSA, 1997: 22-35
42. Friedewald WT, Levy RI, Fredrickson DS. Estimation of the concentration of low density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin Chem 1972; 18: 499-502
43. Boizel R, Benhamou PY, Lardy B, et al. Ratio of triglycerides to HDL cholesterol is an indicator of LDL particle size in patients with type 2 diabetes and normal HDL cholesterol levels. Diabetes Care 2000; 23: 1679-85
44. Assmann G, Cullen P, Schulte H. Simple scoring scheme for calculating the risk of acute coronary events based on the 10 year follow up of the prospective cardiovascular Munster PROCAM study. Circulation 2002; 105: 310-5
45. Assmann G, Cullen P, Schulte H. The Munster Heart Study (PROCAM): results of follow-up at 8 years. Eur Heart J 1998; 19 Suppl. A: A2-A11
46. Stampfer MJ, Sacks FM, Salvini S, et al. A prospective study of cholesterol, apolipoproteins, and the risk of myocardial infarction. N Engl J Med 1991; 325: 373-81
47. Kannel WB. Prevalence, incidence, and mortality of coronary heart disease. In: Fuster V, Ross R, Topol E, editors. Atherosclerosis and coronary artery disease. Philadelphia (PA): Lippincott-Raven, 1996: 13-21
48. Chobanian AV, Bakris GL, Black HR, et al. The seventh report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure: the JNC 7 report. JAMA 2003; 289 (19): 2560-72
49. National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). Third report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) final report. Circulation 2002; 106: 3143-421
50. American Diabetes Association. Management of dyslipidemia in adults with diabetes. Diabetes Care 2003; 26 Suppl. 1: S83-6
51. World Health Organization. Tobacco or health: a global status report. Geneva: WHO, 1997
52. Thompson SG, Pyke SD, Word DA. Using a coronary risk store for screening and intervention in general practice: British Family Heart Study. J Cardiovasc Risk 1996; 3: 301-6
53. Day D. Population-based screening with the Coronary Heart Disease Risk Factor Calculator. Adv Ther 2001; 18: 21-32
54. National Cholesterol Education Program. Detection, evaluation, and treatment of high blood cholesterol in adults (Adult Treatment Panel III) [online]. Available from URL: http://www.nhlbi.nih.gov/guidelines/cholesterol/ [Accessed 2004 Jul 1]
55. Statcoder.com [online]. Available from URL: http://www.statcoder.com/cardiac.htm [Accessed 2004 Sep 8]
56. Marrugat J, Solanas P, D'Agostino R, et al. Estimación del riesgo coronario en España mediante la ecuación de Framingham calibrada. Rev Esp Cardiol 2003; 56: 253-61
57. International Task Force for Prevention of Coronary Heart Disease. PROCAM Risk Calculator [online]. Available from URL: http://www.chd-taskforce.de [Accessed 2004 Sep 8]
58. Conroy RM, Pyorala K, Fitzgerald AP, et al. Estimation of ten-year risk of fatal cardiovascular disease in Europe: the SCORE Project group. Eur Heart J 2003; 24: 987-1003
59. Wood D, De Backer G, Faergeman O, et al. Prevention of coronary heart disease in clinical practice: recommendations of the Second Joint Task Force of European and other Societies on Coronary Prevention. Atherosclerosis 1998; 140: 199-270
60. Pearson TA, Blair SN, Daniels SR, et al. AHA guidelines for primary prevention of cardiovascular disease and stroke, 2002 update: consensus panel guide to comprehensive risk reduction for adult patients without coronary or other atherosclerotic vascular diseases. Circulation 2002; 106: 388-91
61. AHA/ACC guidelines for preventing heart attack and death in patients with atherosclerotic cardiovascular disease, 2001 update: a statement for healthcare professionals from the American Heart Association and the American College of Cardiology. Circulation 2001; 104: 1577-9
62. Stampfer MJ, Krauss RM, Ma J, et al. A prospective study of triglyceride level, low density lipoprotein particle diameter, and risk of myocardial infarction. JAMA 1996; 276: 882-8
63. Criqui MH, Golomb BA. Epidemiologic aspects of lipid abnormalities. Am J Med 1998; 105 Suppl. 1A: 48S-57S
64. Pintó X, Meco JF, Corbella E, et al. Programa de prevención secundaria de la arteriosclerosis del hospital universitario de Bellvitge: resultados principales y predictores del curso clínico. Med Clin (Barc.) 2003; 120: 768-72
65. Kinosian B, Glick H, Garland G. Cholesterol and coronary heart disease: predicting risks by levels and ratios. Ann Intern Med 1994; 121: 641-7
66. Gordon T, Kannel WB. Multiple risk functions for predicting coronary heart disease: the concept, accuracy, and application. Am Heart J 1982; 103: 1031-9
67. Frohlich J, Fodor G, McPherson R, et al. Rationale for and outline of the recommendations of the Working Group on Hypercholesterolemia and Other Dyslipidemias: interim report. Can J Cardiol 1998; 14 Suppl. A: 17-21
68. International Lipid Information Bureau. The ILIB lipid handbook for clinical practice: blood lipids and coronary heart disease. 2nd ed. New York: ILIB, 2000
69. Plaza Pérez I. Programas de prevención secundaria y rehabilitación cardiaca en España. Rev Esp Cardiol 2003; 56: 757-60
70. Pedro-Botet J, Sentí M, Rubiés-Prat J, et al. When to treat dyslipidaemia of patients with chronic renal failure on haemodialysis? A need to define specific guidelines. Nephrol Dial Transplant 1996; 11: 308-13
71. Wanner C. Importance of hyperlipidaemia and therapy in renal patients. Nephrol Dial Transplant 2000; 15 Suppl. 5: 92-6
72. Dube MP, Sprecher D, Henry WK, et al. Preliminary guidelines for the evaluation and management of dyslipidemia in adults infected with human immunodeficiency virus and receiving antiretroviral therapy: 8 recommendations of the Adult AIDS Clinical Trial Group Cardiovascular Disease Focus Group. Clin Infect Dis 2000; 31: 1216-24
73. Penzak SR, Chuck SK. Hyperlipidemia associated with HIV protease inhibitor use: pathophysiology, prevalence, risk factors and treatment. Scand J Infect Dis 2000; 32: 111-23
74. Mooser V, Carr A. Antiretroviral therapy-associated hyperlipidaemia in HIV disease. Curr Opin Lipidol 2001; 12: 313-9
75. Kaplan NM. Treatment of hypertension: drug therapy. In: Kaplan NM, editor. Kaplan's clinical hypertension. Philadelphia (PA): Lippincott Williams & Wilkins, 2002: 237-338
76. Sever PS, Dahlof B, Poulter NR, et al. Prevention of coronary and stroke events with atorvastatin in hypertensive patients who have average or lower-than-average cholesterol concentrations in the Anglo-Scandinavian Cardiac Outcomes Trial, Lipid Lowering Arm (ASCOT-LLA): a multicentre randomised controlled trial. Lancet 2003; 361: 1149-58
77. Dattilo AM, Kris-Etherton PM. Effects of weight reduction on blood lipids and lipoproteins: a meta-analysis. Am J Clin Nutr 1992; 56: 320-8
78. Perez-Jimenez F, Castro P, Lopez-Miranda J, et al. Circulating levels of endothelial function are modulated by dietary monounsaturated fat. Atherosclerosis. 1999; 145: 351-8
79. Ginsberg HN. Nonpharmacologic management of low levels of high density lipoprotein cholesterol. Am J Cardiol 2000; 86 (12A): 41L-5L
80. Marrugat J, Elosua R, Covas M-I, et al. Amount and intensity of physical activity, physical fitness, and serum lipids in men. Am J Epidemiol 1996; 143: 562-569. Erratum in: Am J Epidemiol 1996; 144 (3): 317
81. Hardman AE. Role of exercise and weight loss in maximizing LDL cholesterol reduction. Eur Heart J Suppl 1999; 1 Suppl. S: S123-31
82. Clark RW, Sutfin TA, Ruggeri RB, et al. Raising high density lipoprotein in humans through inhibition of cholesteryl ester transfer protein. Arterioscler Thromb Vasc Biol 2004; 24: 490-7
83. Frick H, Elo O, Haapa K, et al. Helsinki Heart Study. Primary prevention trial with gemfibrozil in middle-aged men with dyslipidemia: safety of treatment, changes in risk factors, and incidence of coronary heart disease. N Engl J Med 1987; 317: 1237-45
84. The BIP Study Group. Secondary prevention by raising HDL-cholesterol and reducing triglycerides in patients with coronary artery disease: the Bezafibrate Infarction Prevention (BIP) Study. Circulation 2000; 102: 21-7
85. Guichard JP, Blouquin P, Qing Y. A new formulation of fenofibrate: suprabioavailable tablets. Curr Med Res Opin 2000; 16 (2): 134-8
86. Packard KA, Backes JM, Lenz TL, et al. Comparison of gemfibrozil and fenofibrate in patients with dyslipidemic coronary heart disease. Pharmacotherapy 2002 Dee; 22 (12): 1527-32
87. Balfour JA, McTavish D, Heel RC. Fenofibrate: a review of its pharmacodynamic and pharmacokinetics properties and therapeutic use in dyslipidaemia. Drugs 1990; 40: 260-90
88. Keating GM, Ormrod D. Micronised fenofibrate: an updated review of its clinical efficacy in the management of dyslipidaemia. Drugs 2002; 62 (13): 1909-44
89. Fruchart JC, Brewer HB, Leitersdorf E. Consensus for the use of fibrates in the treatment of dyslipoproteinemia and coronary heart disease. Am J Cardiol 1998; 81: 912-21
90. Goldberg RB, Mellies MJ, Sacks FM, et al. Cardiovascular events and their reduction with pravastatin in diabetic and glucose-intolerant myocardial infarction survivors with average cholesterol levels: subgroup analyses in the cholesterol and recurrent events (CARE) trial. The CARE investigators. Circulation 1998; 98 (23): 2513-9
91. Fruchart JC, Duriez P. HDL and triglyceride as therapeutic targets. Curr Opin Lipidol 2002; 13: 605-16
92. Bowen PH, Guyton JR. Nonpharmacologic and pharmacologic treatment of patients with low levels of high density lipoprotein cholesterol. Curr Atheroscler Rep 2000; 2: 58-63
93. Morgan JM, Capuzzi DM, Baksh RI, et al. Effects of extended-release niacin on lipoprotein subclass distribution. Am J Cardiol 2003; 91: 1432-6
94. DiPalma JR, Thayer WS. Use of niacin as a drug. Ann Rev Nutr 1991; 11: 169-87
95. Kamanna VS, Kashyap ML. Mechanism of action of niacin on lipoprotein metabolism. Curr Atheroscler Rep 2000; 2: 36-46
96. Scandinavian Simvastatin Survival Study Group. Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease. The Scandinavian Simvastatin Survival Study (4S) Group. Lancet 1994; 344: 1383-9