Isoleucine 69 and valine 325 form a specificity pocket in human muscle creatine kinase

Biochemistry

Volumn 43, Issue 43, 2004, Pages 13766-13774

  Novak, Walter R P ^a   Wang, Pan Fen ^b   McLeish, Michael J ^b   Kenyon, George L ^b   Babbitt, Patricia C ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF MICHIGAN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATALYSIS; ENZYMES; MUSCLE; MUTAGENESIS; SUBSTRATES;

CREATINE KINASE (CK); FLEXIBLE LOOPS; PHOSPHORYLATION;

HUMAN ENGINEERING;

ALANINE; CREATINE KINASE; CYCLOCREATINE; GLUTAMIC ACID; GUANIDINOACETIC ACID; ISOLEUCINE; MUSCLE ENZYME; VALINE;

AMINO ACID SEQUENCE; ARTICLE; ENZYME SPECIFICITY; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS;

AMINO ACID SEQUENCE; ANIMALS; ARGININE KINASE; CATALYSIS; CREATINE KINASE; CREATININE; ENZYME ACTIVATION; ENZYME STABILITY; GLYCINE; HUMANS; ISOENZYMES; ISOLEUCINE; KINETICS; MOLECULAR SEQUENCE DATA; MUSCLE, SKELETAL; MUTAGENESIS, SITE-DIRECTED; SPECIES SPECIFICITY; STRUCTURAL HOMOLOGY, PROTEIN; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY; VALINE;

EID: 7244234097     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi049060y     Document Type: Article

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