Crystal Structures of cobalamin-independent methionine synthase complexed with zinc, homocysteine, and methyltetrahydrofolate

Journal of Biological Chemistry

Volumn 279, Issue 43, 2004, Pages 44235-44238

  Ferrer, Jean Luc ^a   Ravanel, Stéphane ^b   Robert, Mylène ^b   Dumas, Renaud ^b  

^a INSTITUT DE BIOLOGIE STRUCTURALE   (France)

^b CEA GRENOBLE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CATALYSIS; ENZYMES; MOLECULAR STRUCTURE; ORGANOMETALLICS;

BINDING SITES; CATIONIC LOOPS; METALLOENZYMES; MONOMERIC STRUCTURES;

CRYSTAL STRUCTURE;

5 METHYLTETRAHYDROFOLIC ACID; ASPARTIC ACID; CATION; COBALAMIN; CYSTEINE; GLUTAMIC ACID; HISTIDINE; HOMOCYSTEINE; ISOLEUCINE; METHIONINE SYNTHASE; METHYL GROUP; MONOMER; PTERIN; SERINE; SULFUR; TRYPTOPHAN; WATER; ZINC;

AMINO TERMINAL SEQUENCE; ARABIDOPSIS; ARTICLE; ATOM; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CELL SURFACE; COMPLEX FORMATION; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME BINDING; ENZYME STABILITY; ENZYME SUBSTRATE; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION;

5-METHYLTETRAHYDROFOLATE-HOMOCYSTEINE S-METHYLTRANSFERASE; ARABIDOPSIS; BINDING SITES; CATIONS; CRYSTALLOGRAPHY, X-RAY; CYSTEINE; ESCHERICHIA COLI; FOLIC ACID; FOURIER ANALYSIS; HISTIDINE; HOMOCYSTEINE; METHIONINE; METHYLTRANSFERASES; MODELS, MOLECULAR; PLASMIDS; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; SULFUR; TETRAHYDROFOLATES; VITAMIN B 12; ZINC;

ARABIDOPSIS; ARABIDOPSIS THALIANA;

EID: 7244220083     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.C400325200     Document Type: Article

References (27)

1. Gonzalez, J. C., Banerjee, R. V., Huang, S., Sumner, J. S., and Matthews, R. G. (1992) Biochemistry 31, 6045-6056
2. Matthews, R. G. (2001) Acc. Chem. Res. 34, 681-689
3. Kacprzak, M. M., Lewandowska, I., Matthews, R. G., and Paszewski, A. (2003) Biochem. J. 376, 517-524
4. Ravanel, S., Block, M. A., Rippert, P., Jabrin, S., Curien, G., Rebeille, F., and Douce, R. (2004) J. Biol. Chem. 279, 22548-22557
5. Sunden, S. L., Renduchintala, M. S., Park, E. I., Miklasz, S. D., and Garrow, T. A. (1997) Arch. Biochem. Biophys. 345, 171-174
6. Incharoensakdi, A., and Waditee, R. (2000) Curr. Microbiol. 41, 227-231
7. Neuhierl, B., Thanbichler, M., Lottspeich, F., and Bock, A. (1999) J. Biol. Chem. 274, 5407-5414
8. Ranocha, P., Bourgis, F., Ziemak, M. J., Rhodes, D., Gage, D. A., and Hanson, A. D. (2000) J. Biol. Chem. 275, 15962-15968
9. Matthews, R. G., and Goulding, C. W. (1997) Curr. Opin. Chem. Biol. 1, 332-339
10. Evans, J. C., Huddler, D. P., Jiracek, J., Castro, C., Millian, N. S., Garrow, T. A., and Ludwig, M. L. (2002) Structure (Lond.) 10, 1159-1171
11. Gonzalez, B., Pajares, M. A., Martinez-Ripoll, M., Blundell, T. L., and Sanz-Aparicio, J. (2004) J. Mol. Biol. 338, 771-782
12. Evans, J. C., Huddler, D. P., Hilgers, M. T., Romanchuk, G., Matthews, R. G., and Ludwig, M. L. (2004) Proc. Natl. Acad. Sci. U. S. A. 101, 3729-3736
13. Zhou, Z. S., Peariso, K., Penner-Hahn, J. E., and Matthews, R. G. (1999) Biochemistry 38, 15915-15926
14. Peariso, K., Zhou, Z. S., Smith, A. E., Matthews, R. G., and Penner-Hahn, J. E. (2001) Biochemistry 40, 987-993
15. Roth, M., Carpentier, P., Kaïkati, O., Joly, J., Charrault, P., Pirocchi, M., Kahn, R., Fanchon, E., Jacquamet, L., Borel, F., Bertoni, A., Israel-Gouy, P., and Ferrer, J.-L. (2002) Acta Crystallogr. Sect. D Biol. Crystallogr. 58, 805-814
16. Kabsch, W. (1993) J. Appl. Crystallogr. 26, 795-800
17. Terwilliger, T. C., and Berendzen, J. (1999) Acta Crystallogr. Sect. D Biol. Crystallogr. 55, 849-861
18. Terwilliger, T. C. (1999) Acta Crystallogr. Sect. D Biol. Crystallogr. 55, 1863-1871
19. Jones, T. A., Zou, J.-Y., Cowan, S. W., and Kjeldgaard, M. (1993) Acta Crystallogr. Sect. A 49, 148-157
20. Brunger, A. T., Adams, P. D., Clore, G. M., DeLano, W. L., Gros, P., Grosse-Kunstleve, R. W., Jiang, J.-S., Kuszewski, J., Nilges, N., Pannu, N. S., Read, R. J., Rice, L. M., Simonson, T., and Warren, G. L. (1998) Acta Crystallogr. Sect. D Biol. Crystallogr. 54, 905-921
21. Yeates, T. O. (1997) Methods Enzymology 276, 344-358
22. Kraulis, P. J. (1991) J. Appl. Crystallogr. 24, 946-950
23. Fu, T.-F., Scarsdale, J. N., Kazanina, G., Schirch, V., and Wright, H. T. (2003) J. Biol. Chem. 278, 2645-2653
24. Eckermann, C., Eichel, J., and Schröder, J. (2000) Biol. Chem. 381, 695-703
25. Whitfield, C. D., Steers, E. J., Jr., and Weissbach, H. (1970) J. Biol. Chem. 245, 390-401
26. Whitfield, C. D., and Weissbach, H. (1970) J. Biol. Chem. 245, 402-409
27. Schröder, I., and Thauer, E. K. (1999) Eur. J. Biochem. 263, 789-796