Diallyl trisulfide protects rats from carbon tetrachloride-induced liver injury

Journal of Nutrition

Volumn 139, Issue 12, 2009, Pages 2252-2256

  Hosono Fukao, Tomomi ^a,b   Hosono, Takashi ^a,b   Seki, Taiichiro ^a   Ariga, Toyohiko ^a  

^a NIHON UNIVERSITY   (Japan)

^b NATIONAL CENTER FOR GERIATRICS AND GERONTOLOGY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; ALLYL METHYL TRISULFIDE; ASPARTATE AMINOTRANSFERASE; CARBON TETRACHLORIDE; CYTOCHROME P450 2E1; DIALLYL TRISULFIDE; DIBUTYL TRISULFIDE; DIETHYL TRISULFIDE; DIMETHYL TRISULFIDE; DIPROPYLTRISULFIDE; DRUG METABOLIZING ENZYME; GLUTATHIONE TRANSFERASE; SULFIDE; UNCLASSIFIED DRUG;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CONTROLLED STUDY; ENZYME ACTIVITY; HISTOLOGY; LIVER INJURY; LIVER PROTECTION; MALE; NONHUMAN; RAT; SPECTROPHOTOMETRY; WESTERN BLOTTING;

ALANINE TRANSAMINASE; ALLYL COMPOUNDS; ANIMALS; ASPARTATE AMINOTRANSFERASES; CARBON TETRACHLORIDE POISONING; CYTOCHROME P-450 CYP2B1; CYTOCHROME P-450 CYP2E1; LIVER; MALE; RATS; RATS, WISTAR; SOYBEAN OIL; SULFIDES; THIOBARBITURIC ACID REACTIVE SUBSTANCES; WEIGHT GAIN;

RATTUS;

EID: 72249112537     PISSN: 00223166     EISSN: 15416100     Source Type: Journal    
DOI: 10.3945/jn.109.109611     Document Type: Article

References (33)

1. Thomson M, Ali M. Garlic. Curr Cancer Drug Targets. 2003;3:67-81.
2. Peleg A, Hershcovici T, Lipa R, Anbar R, Redler M, Beigel Y. Effect of garlic on lipid profile and psychopathologic parameters in people with mild to moderate hypercholesterolemia. Isr Med Assoc J. 2003;5: 637-640 (Pubitemid 37203532)
3. Lamm DL, Riggs DR. Enhanced immunocompetence by garlic: role in bladder cancer and other malignancies. J Nutr. 2001;131:S1067-70.
4. Ou CC, Tsao SM, Lin MC, Yin MC. Protective action on human LDL against oxidation and glycation by four organosulfur compounds derived from garlic. Lipids. 2003;38:219-224
5. Fleischauer AT, Arab L. Garlic and cancer: a critical review of the epidemiologic literature. J Nutr. 2001;131:S1032-40.
6. Block E. The chemistry of garlic and onions. Sci Am. 1985;252:114-119
7. Fukao T, Hosono T, Misawa S, Seki T, Ariga T. The effects of allyl sulfides on the induction of phase II detoxification enzymes and liver injury by carbon tetrachloride. Food Chem Toxicol. 2004;42:743-749 (Pubitemid 38376341)
8. Fukao T, Hosono T, Misawa S, Seki T, Ariga T. Chemoprotective effect of diallyl trisulfide from garlic against carbon tetrachloride-induced acute liver injury of rats. Biofactors. 2004;21:171-174 (Pubitemid 40921849)
9. Shaik IH, George JM, Thekkumkara TJ, Mehvar R. Protective effects of diallyl sulfide, a garlic constituent, on the warm hepatic ischemiareperfusion injury in a rat model. Pharm Res. 2008;25:2231-2242
10. Raucy JL, Kraner JC, Lasker JM. Bioactivation of halogenated hydrocarbons by cytochrome P4502E1. Crit Rev Toxicol. 1993;23: 1-20.
11. Weber LW, Boll M, Stampfl A. Hepatotoxicity and mechanism of action of haloalkanes: carbon tetrachloride as a toxicological model. Crit Rev Toxicol. 2003;33:105-136 (Pubitemid 36432872)
12. Milligan B, Saville B, Swan JM. New syntheses of trisulphides. J Chem Soc. 1961;4850-4853
13. Chang TK, Crespi CL, Waxman DJ. Spectrophotometric analysis of human CYP2E1-catalyzed p-nitrophenol hydroxylation. Methods Mol Biol. 1998;107:147-152
14. Habig WH, Pabst MJ, Jakoby WB. Glutathione S-transferases. The first enzymatic step in mercapturic acid formation. J Biol Chem. 1974; 249:7130-7139
15. Ernster L. DT diaphorase. Methods Enzymol. 1967;10:309-317
16. Kikugawa K, Kojima T, Yamaki S, Kosugi H. Interpretation of the thiobarbituric acid reactivity of rat liver and brain homogenates in the presence of ferric ion and ethylenediaminetetraacetic acid. Anal Biochem. 1992;202:249-255
17. Munday R, Munday JS, Munday CM. Comparative effects of mono-, di-, tri-, and tetrasulfides derived from plants of the Allium family: redox cycling in vitro and hemolytic activity and Phase 2 enzyme induction in vivo. Free Radic Biol Med. 2003;34:1200-1211 (Pubitemid 36423369)
18. Sheweita SA, El-Gabar MA, Bastawy M. Carbon tetrachloride changes the activity of cytochrome P450 system in the liver of male rats: role of antioxidants. Toxicology. 2001;169:83-92. (Pubitemid 33082115)
19. Zhou S, Gao Y, Jiang W, Huang M, Xu A, Paxton JW. Interactions of herbs with cytochrome P450. Drug Metab Rev. 2003;35:35-98.
20. Koop DR. Oxidative and reductive metabolism by cytochrome P450 2E1. FASEB J. 1992;6:724-730
21. Nordmann R, Ribiere C, Rouach H. Implication of free radical mechanisms in ethanol-induced cellular injury. Free Radic Biol Med. 1992;12:219-240
22. Zaher H, Buters JT, Ward JM, Bruno MK, Lucas AM, Stern ST, Cohen SD, Gonzalez FJ. Protection against acetaminophen toxicity in CYP1A2 and CYP2E1 double-null mice. Toxicol Appl Pharmacol. 1998;152: 193-199 (Pubitemid 28498688)
23. Wong FW, Chan WY, Lee SS. Resistance to carbon tetrachlorideinduced hepatotoxicity in mice which lack CYP2E1 expression. Toxicol Appl Pharmacol. 1998;153:109-118
24. Avasarala S, Yang L, Sun Y, Leung AW, Chan WY, Cheung WT, Lee SS. A temporal study on the histopathological, biochemical and molecular responses of CCl4-induced hepatotoxicity in Cyp2e1-null mice. Toxicology. 2006;228:310-322 (Pubitemid 44708458)
25. Morishima Y, Peng HM, Lin HL, Hollenberg PF, Sunahara RK, Osawa Y, Pratt WB. Regulation of cytochrome P450 2E1 by heat shock protein 90-dependent stabilization and CHIP-dependent proteasomal degradation. Biochemistry. 2005;44:16333-16340 (Pubitemid 41785832)
26. Morris CR, Chen SC, Zhou L, Schopfer LM, Ding X, Mirvish SS. Inhibition by allyl sulfides and phenethyl isothiocyanate of methyl-npentylnitrosamine depentylation by rat esophageal microsomes, human and rat CYP2E1, and rat CYP2A3. Nutr Cancer. 2004;48:54-63. (Pubitemid 38823546)
27. Hosono T, Fukao T, Ogihara J, Ito Y, Shiba H, Seki T, Ariga T. Diallyl trisulfide suppresses the proliferation and induces apoptosis of human colon cancer cells through oxidative modification of b-tubulin. J Biol Chem. 2005;280:41487-41493 (Pubitemid 41832209)
28. Hosono T, Hosono-Fukao T, Inada K, Tanaka R, Yamada H, Iitsuka Y, Seki T, Hasegawa I, Ariga T. Alkenyl group is responsible for the disruption of microtubule network formation in human colon cancer cell line HT-29 cells. Carcinogenesis. 2008;29:1400-1406
29. Robertson IG, Jensson H, Mannervik B, Jernstrom B. Glutathione transferases in rat lung: the presence of transferase 7-7, highly efficient in the conjugation of glutathione with the carcinogenic (+)-7b, 8adihydroxy- 9a, 10a-oxy-7,8,9,10- tetrahydrobenzo[a]pyrene. Carcinogenesis. 1986;7:295-299
30. Berhane K, Widersten M, Engstrom A, Kozarich JW, Mannervik B. Detoxication of base propenals and other a, b-unsaturated aldehyde products of radical reactions and lipid peroxidation by human glutathione transferases. Proc Natl Acad Sci USA. 1994;91:1480-1484 (Pubitemid 24059036)
31. Henderson CJ, Smith AG, Ure J, Brown K, Bacon EJ, Wolf CR. Increased skin tumorigenesis in mice lacking pi class glutathione Stransferases. Proc Natl Acad Sci USA. 1998;95:5275-5280 (Pubitemid 28208588)
32. Nakae D, Denda A, Kobayashi Y, Akai H, Kishida H, Tsujiuchi T, Konishi Y, Suzuki T, Muramatsu M. Inhibition of early-phase exogenous and endogenous liver carcinogenesis in transgenic rats harboring a rat glutathione S-transferase placental form gene. Jpn J Cancer Res. 1998;89:1118-1125 (Pubitemid 29007992)
33. Munday R, Munday CM. Induction of phase II detoxification enzymes in rats by plant-derived isothiocyanates: comparison of allyl isothiocyanate with sulforaphane and related compounds. J Agric Food Chem. 2004;52:1867-1871