1,3-Dipolar cycloaddition of C-aryl-N-phenylnitrones to (R)-1-(1-phenylethyl)-3-[(E)-arylmethylidene]tetrahydro-4(1H)-pyridinone s: Synthesis and antimycobacterial evaluation of enantiomerically pure spiroisoxazolidines

European Journal of Medicinal Chemistry

Volumn 45, Issue 1, 2010, Pages 124-133

  Kumar, Raju Suresh ^a   Perumal, Subbu ^a   Shetty, Krithika Arun ^b   Yogeeswari, Perumal ^b   Sriram, Dharmarajan ^b  

^a MADURAI KAMARAJ UNIVERSITY   (India)

^b BIRLA INSTITUTE OF TECHNOLOGY AND SCIENCE   (India)

Author keywords

[No Author keywords available]

Indexed keywords

1,3,4 TRIPHENYL 7 (1 PHENYLETHYL) 2 OXA 3,7 DIAZASPIRO[4.5]DECAN 10 ONE; 2,3 DIPHENYL 7 (1 PHENYLETHYL) 4 (2 THIENYL) 1 OXA 2,7 DIAZASPIRO[4.5]DECAN 10 ONE; 2,3,4 TRIPHENYL 7 (1 PHENYLETHYL) 1 OXA 2,7 DIAZASPIRO[4.5]DECAN 10 ONE; 3 (4 METHYLPHENYL) 2 PHENYL 7 (1 PHENYLETHYL) 4 (2 THIENYL) 1 OXA 2,7 DIAZASPIRO[4.5]DECAN 10 ONE; 3 (4 METHYLPHENYL) 2,4 PHENYL 7 (1 PHENYLETHYL) 1 OXA 2,7 DIAZASPIRO[4.5]DECAN 10 ONE; 3 (4 METHYLPHENYL) 4 (1 NAPHTHYL) 2 PHENYL 7 (1 PHENYLETHYL) 1 OXA 2,7 DIAZASPIRO[4.5]DECAN 10 ONE; 3,4 BIS(4 CHLOROPHENYL) 7 (1 PHENYLETHYL) 1 OXA 2,7 DIAZASPIRO[4.5]DEC 2 EN 10 ONE; 3,4 DI(4 METHYLPHENYL) 2 PHENYL 7 (1 PHENYLETHYL) 1 OXA 2,7 DIAZASPIRO[4.5]DECAN 10 ONE; 4 (1 NAPHTHYL) 2,3 DIPHENYL 7 (1 PHENYLETHYL) 1 OXA 2,7 DIAZASPIRO[4.5]DECAN 10 ONE; 4 (2 CHLOROPHENYL) 2,3 DIPHENYL 7 (1 PHENYLETHYL) 1 OXA 2,7 DIAZASPIRO[4.5]DEC 2 EN 10 ONE; 4 (2 CHLOROPHENYL) 3 (4 CHLOROPHENYL) 7 (1 PHENYLETHYL) 1 OXA 2,7 DIAZASPIRO[4.5]DEC 2 EN 10 ONE; 4 (2 CHLOROPHENYL) 3 (4 METHYLPHENYL) 2 PHENYL 7 (1 PHENYLETHYL) 1 OXA 2,7 DIAZASPIRO[4.5]DEC 10 ONE; 4 (4 CHLOROPHENYL) 3 (4 METHYLPHENYL) 2 PHENYL 7 (1 PHENYLETHYL) 1 OXA 2,7 DIAZASPIRO[4.5]DEC 2 EN 10 ONE; 4 (4 METHYLPHENYL) 1,3 DIPHENYL 7 (1 PHENYLETHYL) 2 OXA 3,7 DIAZASPIRO[4.5]DECAN 10 ONE; 4 (4 METHYLPHENYL) 2,3 DIPHENYL 7 (1 PHENYLETHYL) 1 OXA 2,7 DIAZASPIRO[4.5]DECAN 10 ONE; ETHAMBUTOL; ISOXAZOLIDINE DERIVATIVE; SPIROISOXAZOLIDINE DERIVATIVE; TUBERCULOSTATIC AGENT; UNCLASSIFIED DRUG;

AGAR DILUTION; ANTIBACTERIAL ACTIVITY; ARTICLE; CONTROLLED STUDY; CRYSTAL STRUCTURE; CYCLOADDITION; DRUG ACTIVITY; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; ENANTIOMER; MINIMUM INHIBITORY CONCENTRATION; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; STEREOCHEMISTRY;

ANTI-BACTERIAL AGENTS; DRUG DISCOVERY; MICROBIAL SENSITIVITY TESTS; MODELS, MOLECULAR; MOLECULAR CONFORMATION; MYCOBACTERIUM TUBERCULOSIS; NITROGEN OXIDES; OXAZOLES; PYRIDONES; STEREOISOMERISM;

EID: 72249100101     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2009.09.034     Document Type: Article

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