Simultaneous cultivation of human endothelial-like differentiated precursor cells and human marrow stromal cells on β-tricalcium phosphate

Tissue Engineering - Part C: Methods

Volumn 15, Issue 4, 2009, Pages 551-560

  Henrich, Dirk ^a   Seebach, Caroline ^a   Kaehling, Christopher ^a   Scherzed, Agmal ^a   Wilhelm, Kerstin ^a   Tewksbury, Robyn ^a   Powerski, MacIej ^a   Marzi, Ingo ^a  

^a GOETHE UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BIOACTIVITY; BIOMATERIALS; BONE; CYTOLOGY; DEFECTS; FLOWCHARTING; GENE EXPRESSION; PEPTIDES; SELF ASSEMBLY; TRANSMISSION CONTROL PROTOCOL;

BIOLOGIC ACTIVITIES; BONE DEFECT; BONE FORMATION; BONE HEALING; BONE-FORMING CELLS; CELL CONSTRUCTS; ENDOTHELIAL DIFFERENTIATION; ENDOTHELIAL PROGENITOR CELLS; GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE; HOUSEKEEPING GENE; HUMAN BONE MARROW; IN-VIVO; MARROW STROMAL CELL; MATRIX; METABOLIC ACTIVITY; NEOVASCULARIZATION; OSTEOCALCIN; OSTEOGENIC; OSTEOGENIC DIFFERENTIATION; PRECURSOR CELLS; TRI-CALCIUM PHOSPHATES; VASCULAR ENDOTHELIAL GROWTH FACTOR; VASCULARIZATION; VASCULOGENESIS;

ENDOTHELIAL CELLS;

CALCIUM PHOSPHATE; COLLAGEN TYPE 1; FIBRONECTIN; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; OSTEOCALCIN; TRANSCRIPTION FACTOR RUNX2; VASCULOTROPIN; VASCULOTROPIN RECEPTOR 2; VON WILLEBRAND FACTOR;

ANGIOGENESIS; ARTICLE; BONE DEVELOPMENT; BONE MARROW; BONE MASS; CELL DIFFERENTIATION; CELL SIZE; GENE EXPRESSION; HUMAN CELL CULTURE; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; NUCLEOTIDE SEQUENCE; OSSIFICATION; PRIORITY JOURNAL; RAT; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STEM CELL; STROMA CELL; VASCULARIZATION;

RATTUS;

EID: 72249087338     PISSN: 19373384     EISSN: 19373392     Source Type: Journal    
DOI: 10.1089/ten.tec.2008.0385     Document Type: Article

References (33)

1. Vacanti, J.P., Langer, R., Upton, J., and Marler, J.J. Transplantation of cells in matrices for tissue regeneration. Adv Drug Deliv Rev 33, 165, 1998.
2. Maus, U., Andereya, S., Gravius, S., Ohnsorge, J.A., Niedhart, C., and Siebert, C.H. BMP-2 incorporated in a tricalcium phosphate bone substitute enhances bone remodeling in sheep. J Biomater Appl 22, 559, 2008.
3. Pittenger, M.F., Mackay, A.M., Beck, S.C., Jaiswal, R.K., Douglas, R., Mosca, J.D., Moorman, M.A., Simonetti, D.W., Craig, S., and Marshak, D.R. Multilineage potential of adult human mesenchymal stem cells. Science 284, 143, 1999.
4. Peng, H., Wright, V., Usas, A., Gearhart, B., Shen, H.C., Cummins, J., and Huard, J. Synergistic enhancement of bone formation and healing bystem cell-expressed VEGF and bone morphogenetic protein-4. J Clin Invest 110, 751, 2002.
5. Arkudas, A., Beier, J.P., Heidner, K., Tjiawi, J., Polykandriotis, E., Srour, S., Sturzl, M., Horch, R.E., and Kneser, U. Axial prevascularization of porous matrices using an arteriovenous loop promotes survival and differentiation of transplanted autologous osteoblasts. Tissue Eng 13, 1549, 2007.
6. Asahara, T., Murohara, T., Sullivan, A., Silver, M., van der Zee, R., Li, T., Witzenbichler, B., Schatteman, G., and Isner, J.M. Isolation of putative progenitor endothelial cells for angiogenesis. Science 14, 964, 1997.
7. Frank, J., Gorantla, V.S., Anderson, G.L., Laurentin-Perez, L., Maldonado, C., and Barker, J.H. Microcirculation research for microsurgeons: basic concepts and potential applications. Eur J Trauma 4, 153, 2001.
8. Crosby, J.R., Kaminski, W.E., Schatteman, G., Martin, P.J., Raines, E.W., Seifert, R.A., and Bowen-Pope, D.F. Endothelial cells of hematopoetic origin make a significant contribution to adult blood vessel formation. Circ Res 87, 728, 2000.
9. Zhang, S.J., Zhang, H., Hou, M., Zheng, Z., Zhou, J., Su, W., Wei, Y., and Hu, S. Is it possible to obtain ''true endothelial progenitor cells'' by in vitro culture of bone marrow mono-nuclear cells? Stem Cells Dev 16, 683, 2007.
10. Assmus, B., Schachinger, V., Teupe, C., Britten, M., Lehmann, R., Dobert, N., Grunwald, F., Aicher, A., Urbich, C., Martin, H., Hoelzer, D., Dimmeler, S., and Zeiher, A.M. Transplantation of progenitor cells and regeneration enhancement in acute myocardial infarction (TOPCARE-AMI). Circulation 106, 3009, 2002.
11. Fernandez Pujol, B., Lucibello, F.C., Zuzarte, M., Lutjens, P., Muller, R., and Havemann, K. Dendritic cells derived from peripheral monocytes express endothelial markers and in the presence of angiogenic growth factors differentiate into endothelial-like cells. Eur J Cell Biol 80, 99, 2001.
12. Rehman, J., Li, J., Orschell, C.M., and March, K.L. Peripheral blood ''endothelial progenitor cells'' are derived from monocyte=macrophages and secrete angiogenic growth factors. Circulation 107, 1164, 2003.
13. Henrich, D., Hahn, P., Wahl, M., Wilhelm, K., Dernbach, E., Dimmeler, S., and Marzi, I. Serum derived from multiple trauma patients promotes the differentiation of endothelial progenitor cells in vitro: possible role of transforming growth factor-beta1 and vascular endothelial growth factor165. Shock 21, 13, 2004.
14. Henrich, D., Seebach, C., Wilhelm, K., and Marzi, I. High dosage of simvastatin reduces TNF-alpha-induced ap-optosis of endothelial progenitor cells but fails to prevent apoptosis induced by IL-1beta in vitro. J Surg Res 142, 13, 2007.
15. Seebach, C., Henrich, D., Tewksbury, R., Wilhelm, K., and Marzi, I. Number and proliferative capacity of human mesenchymal stem cells are modulated positively in multiple trauma patients and negatively in atrophic nonunions. Calcif Tissue Int 80, 294, 2007.
16. Ohura, K., Hamanishi, C., Tanaka, S., and Matsuda, N. Healing of segmental bone defects in rats induced by a beta-TCP-MCPM cement combined with rhBMP-2. J Biomed Mater Res 44, 168, 1999.
17. Boo, J.S., Yamada, Y., Okazaki, Y., Hibino, Y., Okada, K., Hata, K., Yoshikawa, T., Sugiura, Y., and Ueda, M. Tissue-engineered bone using mesenchymal stem cells and a biodegradable scaffold. J Cranio Fac Surg 13, 231, 2002.
18. Bruder, S.P., Kurth, A.A., Shea, M., Hayes, W.C., Jaiswal, N., and Kadiyala, S. Bone regeneration by implantation of purified, culture-expanded human mesenchymal stem cells. J Orthop Res 16, 155, 1998.
19. Takahashi, Y., Yamamoto, M., and Tabata, Y. Osteogenic differentiation of mesenchymal stem cells in biodegradable sponges composed of gelatin and beta-tricalcium phosphate. Biomaterials 26, 3587, 2005.
20. Okuyama, H., Krishnamachary, B., Zhou, Y.F., Nagasawa, H., Bosch-Marce, M., and Semenza, G.L. Expression of vascular endothelial growth factor receptor 1 in bone marrow-derived mesenchymal cells is dependent on hypoxia-inducible factor 1. J Biol Chem 281, 15554, 2006.
21. Liu, J.W., Dunoyer-Geindre, S., Serre-Beinier, V., Mai, G., Lambert, J.F., Fish, R.J., Pernod, G., Buehler, L., Bouna-meaux, H., and Kruithof, E.K. Characterization of endothe-lial-like cells derived from human mesenchymal stem cells. J Thromb Haemost 5, 826, 2007.
22. Takahashi, T., Kalka, C., Masuda, H., Chen, D., Silver, M., Kearney, M., Magner, M., Isner, J.M., and Asahara, T. Ischemia-and cytokine induced mobilization of bone-marrow derived endothelial progenitor cells for neovascu-larization. Nat Med 5, 434, 1999.
23. Suh, W., Kim, K.L., Kim, J.M., Shin, I.S., Lee, Y.S., Lee, J.Y., Jang, H.S., Lee, J.S., Byun, J., Choi, J.H., Jeon, E.S., and Kim, D.K. Transplantation of endothelial progenitor cells accelerates dermal wound healing with increased recruitment of monocytes=macrophages and neovascularization. Stem Cells 23, 1571, 2005.
24. Schmeisser, A., Garlichs, C.D., Zhang, H., Eskafi, S., Graffy, C., Ludwig, J., Strasser, R.H., and Daniel, W.G. Monocytes express endothelial and macrophagocytic lineage markers and form cord-like structures in Matrigel under angiogenic conditions. Cardiovasc Res 49, 671, 2001.
25. Kubarev, O.L., Komlev, V.S., Maitz, M., and Barinov, S.M. Bioactive composite ceramics in the hydroxyapatite-tricalcium phosphate system. Dokl Chem 413, 72, 2007.
26. Schmal, H., Niemeyer, P., Roesslein, M., Hartl, D., Loop, T., Südkamp, N.P., Stark, G.B., and Mehlhorn, A.T. Comparison of cellular functionality of human mesenchymal stromal cells and PBMC. Cytotherapy 9, 69, 2007.
27. Vogel, J.P., Szalay, K., Geiger, F., Kramer, M., Richter, W., and Kasten, P. Platelet-rich plasma improves expansion of human mesenchymal stem cells and retains differentiation capacity and in vivo bone formation in calcium phosphate ceramics. Platelets 17, 462, 2006.
28. Ball, S.G., Shuttleworth, A.C., and Kielty, C.M. Direct cell contact influences bone marrow mesenchymal stem cell fate. Int J Biochem Cell Biol 36, 714, 2004.
29. Sun, H., Qu, Z., Guo, Y., Zang, G., and Yang, B. In vitro and in vivo effects of rat kidney vascular endothelial cells on osteogenesis of rat bone marrow mesenchymal stem cells growing on polylactide-glycoli acid (PLGA) scaffolds. Biomed Eng Online 6, 41, 2007.
30. Kaigler, D., Krebsbach, P.H., Wang, Z., West, E.R., Horger, K., and Mooney, D.J. Transplanted endothelial cells enhance orthotopic bone regeneration. J Dent Res 85, 633, 2006.
31. Usami, K., Mizuno, H., Okada, K., Narita, Y., Aoki, M., Kondo, T., Mizuno, D., Mase, J., Nishiguchi, H., Kagami, H., and Ueda, M. Composite implantation of mesenchymal stem cells with endothelial progenitor cells enhances tissue-engineered bone formation.JBiomed Mater Res 90A, 730, 2008.
32. Kähling, C., Seebach, C., Henrich, D., and Marzi, I. Early vascularization and new bone formation in a critical bone defect is improved by co-culture of endothelial progenitor cells (EPC) and mesenchymal stem cells (MSC) in rats. 2nd International Symposium on Biotechnology in Muscosceletal Repair, October 2-4, 2008, Lausanne, Switzerland.
33. Kuwana, M., Okazaki, Y., Kodama, H., Satoh, T., Kawakami, Y., and Ikeda, Y. Endothelial differentiation potential of human monocyte-derived multipotential cells. Stem Cells 24, 2733, 2006.