Effect of phytomedicines, AM-1, niprisan® and nifadin on the pharmacokinetics of chloroquine in rats

European Journal of Drug Metabolism and Pharmacokinetics

Volumn 34, Issue 3-4, 2009, Pages 151-155

  Mustapha, K B ^a   Bakare Odunola, M T ^b   Garba, M ^b   Obodozie, O O ^a   Enemali, I S ^b   Inyan, U S ^a  

^a NATIONAL INSTITUTE FOR PHARMACEUTICAL RESEARCH AND DEVELOPMENT   (Nigeria)

^b AHMADU BELLO UNIVERSITY   (Nigeria)

Author keywords

Chloroquine; Drug interaction; Pharmacokinetics; Phytomedicines; Rats

Indexed keywords

ANTIMALARIAL AGENT; CHLOROQUINE; HERBACEOUS AGENT; NIFADIN; NIPRISAN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DRUG ABSORPTION; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG HALF LIFE; HERB DRUG INTERACTION; HERBAL MEDICINE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MALE; MAXIMUM PLASMA CONCENTRATION; NONHUMAN; RAT;

EID: 72149130520     PISSN: 03787966     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF03191166     Document Type: Article

References (12)

1. Kean B.H. (1979): Chloroquine-resistant falciparum malaria from Africa. JAMA, 241, 95.
2. Nicholas W. (1999): Antimalarial Drug resistance and combination chemotherapy. Trans. R. Soc. Lond., Pp. 739-749.
3. Trape J.F. (2001): The public health impact of chloroquine resistance in Africa. Am. J. Hygen. Trop. Med., 64: 12-17.
4. Hall A.P. (1973): Quinine and chloroquine antagonism in falciparum malarial. Tran. R. Soc. Trop. Med. Hyg., 67: 425-428.
5. Lown K.S., Bailey D.G., Fontana R.J., Janardan S.K., Adair C.H., Fortlage L.A. (1997): Grapefruit juice felodipine oral availability in human by decreasing intestinal CYP3A4 protein expression. J. Clin. Invest., 99: 2545-2553.
6. Bailey D.G., Malcolm J., Arnold O. and Spence J.D. (1998): Grapefruit juice-drug interaction [review]. Br. J. Clin. Pharmacol., 46: 101-110.
7. McNeece J (2002): Grapefruit juice interactions. Aust. Prescr., 25: 37-38.
8. Piscitelli S.C, Brstein A.H, Weldon N., Gallicano K.D. and Falloon J. (2002): The effect of garlic supplements on the pharmacokinetics of saquinavir. Clin. Infect. Dis., 34: 234-338.
9. Koury R.T.G.A. (2003): Issues warning on Hericum. J. Aust. Trad. Med. Soc., 6: 47-49.
10. th European Congress of Bio-harmaceutics and Pharmacokinetics. pp 43-46.
11. Ademowo O.G., Sodeinde O., Walker M.D. (2000): The disposition of chloroquine and its main metabolite desethyl-chloroquine in volunteers with and without chloroquine- induced pruritus: Evidence for decreased chloroquine metabolism in volunteers with pruritus. Clin. Pharmac. Therap., 67: 237-243.
12. Nwafor S.V., Peter A.A., Charles O.O., Adaoma C.O. and Chukwuemeka S.N. (2003): Interaction between chloroquine sulphate and aqueous extract of Azadirachta indica A. Juss (Meliaceae) in rabbits. Acta Pharm.,53: 305-311.