A common mutation in paraoxonase-2 results in impaired lactonase activity

Journal of Biological Chemistry

Volumn 284, Issue 51, 2009, Pages 35564-35571

  Stoltz, David A ^a   Ozer, Egon A ^b   Recker, Thomas J ^a   Estin, Miriam ^a   Yang, Xia ^c   Shih, Diana M ^d   Lusis, Aldons J ^d,e   Zabner, Joseph ^a  

^a UNIVERSITY OF IOWA   (United States)

^b NORTHWESTERN UNIVERSITY   (United States)

^c ROSETTA INPHARMATICS   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYMATIC ACTIVITIES; HUMAN LUNG; IN-VIVO; INNATE IMMUNITY; LACTONASE ACTIVITY; PROTEIN PRODUCTION; SINGLE NUCLEOTIDE POLYMORPHISMS;

AMINO ACIDS; PASSIVE NETWORKS; POLYMORPHISM;

ENZYME ACTIVITY;

ARYLDIALKYLPHOSPHATASE 2; GLUCONOLACTONASE;

ANIMAL CELL; ARTICLE; CODON; CONTROLLED STUDY; DEGLYCOSYLATION; ENDOPLASMIC RETICULUM; ENZYME ACTIVITY; GENE FUNCTION; GENE LINKAGE DISEQUILIBRIUM; GENE MUTATION; GENETIC SCREENING; GENETIC VARIABILITY; GLYCOSYLATION; HETEROZYGOSITY; HOMOZYGOSITY; INNATE IMMUNITY; NONHUMAN; NUCLEIC ACID BASE SUBSTITUTION; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN LOCALIZATION; PROTEIN SYNTHESIS; SINGLE NUCLEOTIDE POLYMORPHISM;

AMINO ACID SUBSTITUTION; ANIMALS; ARYLDIALKYLPHOSPHATASE; ATHEROSCLEROSIS; CHO CELLS; CRICETINAE; CRICETULUS; GLYCOSYLATION; HUMANS; IMMUNITY, INNATE; LUNG; POLYMORPHISM, SINGLE NUCLEOTIDE;

EID: 72149121560     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.051706     Document Type: Article

References (40)

1. Primo-Parmo, S. L., Sorenson, R. C., Teiber, J., and La Du, B. N. (1996) Genomics 33, 498-507
2. Mochizuki, H., Scherer, S. W., Xi, T., Nickle, D. C., Majer, M., Huizenga, J. J., Tsui, L. C., and Prochazka, M. (1998) Gene 213, 149-157
3. Camps, J., Marsillach, J., and Joven, J. (2009) Crit. Rev. Clin. Lab. Sci. 46, 83-106
4. Durrington, P. N., Mackness, B., and Mackness, M. I. (2001) Arterioscler. Thromb. Vasc. Biol. 21, 473-480
5. Furlong, C. E. (2007) J. Biochem. Mol. Toxicol. 21, 197-205
6. Bhattacharyya, T., Nicholls, S. J., Topol, E. J., Zhang, R., Yang, X., Schmitt, D., Fu, X., Shao, M., Brennan, D. M., Ellis, S. G., Brennan, M. L., Allayee, H., Lusis, A. J., and Hazen, S. L. (2008) JAMA 299, 1265-1276
7. Erlich, P. M., Lunetta, K. L., Cupples, L. A., Huyck, M., Green, R. C., Baldwin, C. T., and Farrer, L. A. (2006) Hum. Mol. Genet. 15, 77-85
8. Humbert, R., Adler, D. A., Disteche, C. M., Hassett, C., Omiecinski, C. J., and Furlong, C. E. (1993) Nat. Genet. 3, 73-76
9. Zintzaras, E., and Hadjigeorgiou, G. M. (2004) J. Hum. Genet. 49, 474-481
10. Furlong, C. E., Cole, T. B., Jarvik, G. P., Pettan-Brewer, C., Geiss, G. K., Richter, R. J., Shih, D. M., Tward, A. D., Lusis, A. J., and Costa, L. G. (2005) Neurotoxicology 26, 651-659
11. Draganov, D. I., and La Du, B. N. (2004) Naunyn. Schmiedebergs Arch. Pharmacol. 369, 78-88
12. Khersonsky, O., and Tawfik, D. S. (2005) Biochemistry 44, 6371-6382
13. Ozer, E. A., Pezzulo, A., Shih, D. M., Chun, C., Furlong, C., Lusis, A. J., Greenberg, E. P., and Zabner, J. (2005) FEMS Microbiol. Lett. 253, 29-37
14. Teiber, J. F., Horke, S., Haines, D. C., Chowdhary, P. K., Xiao, J., Kramer, G. L., Haley, R. W., and Draganov, D. I. (2008) Infect. Immun. 76, 2512-2519
15. Draganov, D. I., Teiber, J. F., Speelman, A., Osawa, Y., Sunahara, R., and La Du, B. N. (2005) J. Lipid Res. 46, 1239-1247
16. Teiber, J. F., Draganov, D. I., and La Du, B. N. (2003) Biochem. Pharmacol. 66, 887-896
17. Bassler, B. L., and Losick, R. (2006) Cell 125, 237-246
18. Parsek, M. R., and Greenberg, E. P. (2000) Proc. Natl. Acad. Sci. U.S.A. 97, 8789-8793
19. Stoltz, D. A., Ozer, E. A., Ng, C. J., Yu, J. M., Reddy, S. T., Lusis, A. J., Bourquard, N., Parsek, M. R., Zabner, J., and Shih, D. M. (2007) Am. J. Physiol. Lung Cell. Mol. Physiol. 292, L852-L860
20. Chun, C. K., Ozer, E. A., Welsh, M. J., Zabner, J., and Greenberg, E. P. (2004) Proc. Natl. Acad. Sci. U.S.A. 101, 3587-3590
21. Stoltz, D. A., Ozer, E. A., Taft, P. J., Barry, M., Liu, L., Kiss, P. J., Moninger, T. O., Parsek, M. R., and Zabner, J. (2008) J. Clin. Invest. 118, 3123-3131
22. Pearson, J. P., Gray, K. M., Passador, L., Tucker, K. D., Eberhard, A., Iglewski, B. H., and Greenberg, E. P. (1994) Proc. Natl. Acad. Sci. U.S.A. 91, 197-201
23. Karp, P. H., Moninger, T., Weber, S. P., Nesselhauf, T. S., Launspach, J., Zabner, J., and Welsh, M. J. (2002) in Epithelial Cell Culture Protocols (Wise, C., ed) pp. 115-137, Humana Press, Inc., Totowa, NJ
24. Josse, D., Ebel, C., Stroebel, D., Fontaine, A., Borges, F., Echalier, A., Baud, D., Renault, F., Le Maire, M., Chabrieres, E., and Masson, P. (2002) J. Biol. Chem. 277, 33386-33397
25. Gan, K. N., Smolen, A., Eckerson, H. W., and La Du, B. N. (1991) Drug Metab. Dispos. 19, 100-106
26. Horke, S., Witte, I., Wilgenbus, P., Krüger, M., Strand, D., and Förstermann, U. (2007) Circulation 115, 2055-2064
27. Martinelli, N., Girelli, D., Olivieri, O., Stranieri, C., Trabetti, E., Pizzolo, F., Friso, S., Tenuti, I., Cheng, S., Grow, M. A., Pignatti, P. F., and Corrocher, R. (2004) Eur. J. Clin. Invest. 34, 14-20
28. Chen, Q., Reis, S. E., Kammerer, C. M., McNamara, D. M., Holubkov, R., Sharaf, B. L., Sopko, G., Pauly, D. F., Merz, C. N., and Kamboh, M. I. (2003) Am. J. Hum. Genet. 72, 13-22
29. Leus, F. R., Zwart, M., Kastelein, J. J., and Voorbij, H. A. (2001) Atherosclerosis 154, 641-649
30. Shi, J., Zhang, S., Tang, M., Liu, X., Li, T., Han, H., Wang, Y., Guo, Y., Zhao, J., Li, H., and Ma, C. (2004) Brain Res. Mol. Brain Res. 120, 201-204
31. Slowik, A., Wloch, D., Szermer, P., Wolkow, P., Malecki, M., Pera, J., Turaj, W., Dziedzic, T., Klimkowicz-Mrowiec, A., Kopec, G., Figlewicz, D. A., and Szczudlik, A. (2007) Cerebrovasc. Dis. 23, 395-400
32. Richter, R. J., and Furlong, C. E. (1999) Pharmacogenetics 9, 745-753
33. Jarvik, G. P., Rozek, L. S., Brophy, V. H., Hatsukami, T. S., Richter, R. J., Schellenberg, G. D., and Furlong, C. E. (2000) Arterioscler. Thromb. Vasc. Biol. 20, 2441-2447
34. Wills, A. M., Landers, J. E., Zhang, H., Richter, R. J., Caraganis, A. J., Cudkowicz, M. E., Furlong, C. E., and Brown, R. H., Jr. (2008) Neurology 70, 929-934
35. Harel, M., Aharoni, A., Gaidukov, L., Brumshtein, B., Khersonsky, O., Meged, R., Dvir, H., Ravelli, R. B., McCarthy, A., Toker, L., Silman, I., Sussman, J. L., and Tawfik, D. S. (2004) Nat. Struct. Mol. Biol. 11, 412-419
36. Kuo, C. L., and La Du, B. N. (1995) Drug Metab. Dispos. 23, 935-944
37. Brushia, R. J., Forte, T. M., Oda, M. N., La Du, B. N., and Bielicki, J. K. (2001) J. Lipid Res. 42, 951-958
38. Billecke, S., Draganov, D., Counsell, R., Stetson, P., Watson, C., Hsu, C., and La Du, B. N. (2000) Drug Metab. Dispos. 28, 1335-1342
39. Josse, D., Xie, W., Renault, F., Rochu, D., Schopfer, L. M., Masson, P., and Lockridge, O. (1999) Biochemistry 38, 2816-2825
40. Altshuler, D., Daly, M. J., and Lander, E. S. (2008) Science 322, 881-888