Screening ionisation and chromatography conditions for quantitative LC/MS methods

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 877, Issue 29, 2009, Pages 3581-3588

  Sillén, Henrik ^a   Magnell, Niklas ^a  

^a ASTRAZENECA R AND D   (Sweden)

Author keywords

Bioanalysis; HPLC columns; Interfaces; Ionisation; LC MS; Method development; Mobile phase buffer effects; Optimisation; Quantitative

Indexed keywords

BIOANALYSIS; IONISATION; METHOD DEVELOPMENT; MOBILE PHASE BUFFER; OPTIMISATIONS;

ATMOSPHERIC MOVEMENTS; ATMOSPHERIC PRESSURE; CHROMATOGRAPHIC ANALYSIS; CHROMATOGRAPHY; DISSOLUTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HIGH PRESSURE LIQUID CHROMATOGRAPHY; IONIZATION; MASS SPECTROMETERS; OPTIMIZATION; SPECTROMETRY;

PHASE INTERFACES;

1 (CYCLOHEXYLAMINO) 3 [(2 METHYL 1H INDOL 4 YL)OXY] 2 PROPANOL; 2 (1 AMANTYL)QUINOLINE 4 CARBOXYLIC ACID; 2 [(4 CHLOROBENZYL)AMINO] 1,1 DIPHENYL 1 ETHANOL; 2 BENZYLAMINO 1,1 DIPHENYL 1 ETHANOL; ACETONITRILE; ACICLOVIR; CAFFEINE; DINAPHTHYLPROLINOL; METHANOL; PINDOLOL; QUINOLINE DERIVATIVE; SOLVENT; TESTOSTERONE; THEOPHYLLINE; UNCLASSIFIED DRUG;

ANALYTIC METHOD; ARTICLE; CHEMICAL STRUCTURE; CHROMATOGRAPHY; FLOW INJECTION ANALYSIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INTERMETHOD COMPARISON; IONIZATION; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SCREENING;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHROMATOGRAPHY, LIQUID; MASS SPECTROMETRY;

EID: 72149093798     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2009.08.049     Document Type: Article

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